Abstract:
:The purpose of the present study was to examine the effects of a newly developed water-soluble reduced chitosan on Streptococcus mutans, plaque regrowth, and biofilm vitality. A 1.0%, water-soluble reduced chitosan, with pH ranging from 6.0 to 6.5, molecular weights between 3,000 and 5,000 Da, and 70% degree of deacetylation, was used. To determine antibacterial and antiplaque potency of chitosan, minimal inhibitory concentrations (MICs) for S. mutans and S. sanguinis (formerly S. sanguis), short-term exposure to S. mutans, and clinical trial of plaque regrowth and biofilm vitality were conducted. Twelve dental students volunteered to participate in the 6-week, double blind, randomized clinical trial using the classical 4-day plaque regrowth design. The MIC of water-soluble reduced chitosan for S. mutans was 1.25 g/l. While the cells exposed to distilled water (DW) grew rapidly, with a maximum turbidity reached by 16 h postinoculation, S. mutans exposed to chitosan (5.0 g/l) exhibited a substantial delay in growth and reached a maximum turbidity by 32 h postinoculation. The chitosan solution reduced the plaque index and the vitality of the plaque flora significantly when compared to DW, but this was less than the reductions found with the positive control of 0.1% chlorhexidine solution. The water-soluble reduced chitosan exhibited potent antibacterial effect on S. mutans, and displayed a significant antibacterial and plaque-reducing action during the 4-day plaque regrowth.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Bae K,Jun EJ,Lee SM,Paik DI,Kim JBdoi
10.1007/s00784-006-0038-3keywords:
subject
Has Abstractpub_date
2006-06-01 00:00:00pages
102-7issue
2eissn
1432-6981issn
1436-3771journal_volume
10pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:The present study aimed to identify and quantify the elution of monomers of five different resin-based CAD/CAM blocks (RCBs) using HPLC. METHODS:Five different RCBs were used in the study: GC Cerasmart (CS), Voco Grandio blocs (GR), 3M Lava Ultimate (LU), Shofu Block (SB), and Vita Enamic (VE). Fifteen sampl...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03377-3
更新日期:2021-01-01 00:00:00
abstract::The aims of the present study were: a) to assess the impact of the intraoral location on the rate of biofilm growth, and b) to establish an in vivo biofilm model to examine intraoral biofilm growth. Eight healthy volunteers wore acrylic splints with 15 glass slabs each in the upper and lower jaws to build up plaque. A...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-004-0255-6
更新日期:2004-06-01 00:00:00
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journal_title:Clinical oral investigations
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doi:10.1007/s00784-020-03662-1
更新日期:2020-11-05 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1167-0
更新日期:2014-11-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0570-7
更新日期:2012-06-01 00:00:00
abstract:INTRODUCTION:Decay of teeth, erosion and disintegration of hard dental tissue are a clinically often seen side effect after radiotherapy for tumours in the head and neck region. To investigate if these side effects are due to structural changes in dental hard tissues, the current literature was searched. It can influen...
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pub_type: 杂志文章,评审
doi:10.1007/s00784-013-1034-z
更新日期:2014-01-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0787-0
更新日期:2013-05-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s00784-014-1376-1
更新日期:2015-03-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03499-8
更新日期:2020-08-10 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-013-1169-y
更新日期:2014-11-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1825-0
更新日期:2017-04-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-009-0314-0
更新日期:2010-08-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03430-1
更新日期:2020-07-29 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
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更新日期:2020-02-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1247-9
更新日期:2015-03-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0582-3
更新日期:2012-04-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1929-6
更新日期:2017-03-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,meta分析,评审
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更新日期:2015-07-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0805-2
更新日期:2013-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2017-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00784-007-0120-5
更新日期:2007-09-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-0985-4
更新日期:2014-01-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840050038
更新日期:1998-03-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840050087
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the periodontal healing pattern of dehiscence-type defects following different chemical root conditioning modalities. MATERIALS AND METHODS:Buccal osseous dehiscence defects were created on six teeth of seven dogs. After dental plaque accumulation, defects were tr...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0848-4
更新日期:2013-07-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-003-0238-z
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVES:The purpose of this prospective clinical trial was to examine the clinical and patient outcomes following esthetic reconstruction of interdental papilla loss in anterior teeth, using an injectable, non-animal-based, hyaluronic acid gel. MATERIALS AND METHODS:Ten systemically healthy adults, with at least on...
journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章
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更新日期:2016-09-01 00:00:00
abstract::Denture-related stomatitis (DRS) is still a dilemma in removable prosthodontics. The aim of this study was to investigate the relationship of DRS with the presence of Candida albicans hyphae and Lactobacillus. A total of 91 patients wearing maxillary and mandibular complete dentures were included in the present study ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-008-0240-6
更新日期:2009-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-12-01 00:00:00