Abstract：
OBJECTIVE:Information about the spectrum of microorganisms in the intraimplant cavities of two-piece dental implants is scarce. The purpose of this study was to assess the intraimplant microflora of two-piece dental implants by conventional biochemical testing, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), and 16 s rDNA gene sequencing. MATERIALS AND METHODS:Ten patients (six men and four women; average age = 66.7 years; age range = 58-78 years) received 35 two-piece titanium implants carrying ball attachments. Biofilm sampling was performed with sterile microbrushes, and nonadherent microbial samples were obtained by injection and reuptake of predefined volumes of NaCl solution. The samples were cultured and analyzed by conventional biochemical testing, MALDI-TOF MS, and 16 s rDNA gene sequencing. RESULTS:Of the 103 species detected, 27 and 33 were identified only in the biofilm and nonadherent microbial samples, respectively. Forty-three species were identified in both types of samples. CONCLUSIONS:Two-piece dental implants harbored a broad spectrum of gram-positive and gram-negative aerobes and anaerobes, especially rods and cocci. CLINICAL RELEVANCE:These findings confirm bacterial translocation from the oral cavity to intraimplant cavities. Microbiological methods as used in this study are necessary to reveal the complete vital microflora of intraimplant cavities.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Harder S,Podschun R,Grancicova L,Mehl C,Kern Mdoi
10.1007/s00784-012-0805-2subject
Has Abstractpub_date
2013-05-01 00:00:00pages
1135-42issue
4eissn
1432-6981issn
1436-3771journal_volume
17pub_type
杂志文章abstract：OBJECTIVES:A multicentric randomized, 3-year prospective study was conducted to determine for how long Biodentine, a new biocompatible dentine substitute, can remain as a posterior restoration. MATERIALS AND METHODS:First, Biodentine was compared to the composite Z100®, to evaluate whether and for how long it could be...
journal_title：Clinical oral investigations
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00784-012-0701-9
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to evaluate the effect of simulated gastric acid solution on surface topography and bending properties of esthetic coated nickel-titanium (NiTi) archwires. MATERIALS AND METHODS:Three brands of as-received white-coated superelastic NiTi upper archwires were used in this study: D...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03438-7
更新日期：2020-07-03 00:00:00
abstract：:The aim of this study was to evaluate the clinical long-term performance of a visible light-cured resin (VLCR) denture base material and to compare it to a well-established polymethylmethacrylate (PMMA)-based denture acrylic in a randomized split-mouth clinical long-term study. One hundred removable partial dentures i...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-011-0572-5
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVE:Azithromycin is a macrolide antibiotic that appears to have both antibacterial and anti-inflammatory properties. This study aimed to investigate the effect of azithromycin on the production of pro-inflammatory cytokines and chemokines by human gingival fibroblasts (HGF) in vitro. MATERIALS AND METHODS:The ef...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-014-1249-7
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVES:A group of adolescents with oral piercings was studied to determine the presence of metallic particles in cells exfoliated from the mucosa surrounding their metal oral piercings and the association between such particles and the metal jewelry, and to evaluate subsequent tissue implications. MATERIALS AND ME...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2626-4
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVES:The aim of the present study is to provide a detailed macroscopic mapping of the palatal and tuberal blood supply applying anatomical methods and studying specific anastomoses to bridge the gap between basic structural and empirical clinical knowledge. MATERIALS AND METHODS:Ten cadavers (three dentate, seve...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2538-3
更新日期：2019-03-01 00:00:00
abstract：:The aims of this study were threefold: (1) to describe iatrogenic lesions to oral branches of the trigeminal nerve, signs and symptoms, and functional status, (2) to report on a simple neurosensory examination method, and (3) to discuss means of prevention of iatrogenic injury. The etiology and functional status of 44...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-006-0089-5
更新日期：2007-06-01 00:00:00
abstract：OBJECTIVES:The purpose of this experimental in vivo investigation was to evaluate the influence of modifying the implant surface by adding a monolayer of multi-phosphonate molecules on the development of experimental peri-implantitis. MATERIAL AND METHODS:Eight beagle dogs received 5 tests and 5 control implants each ...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03708-4
更新日期：2021-01-06 00:00:00
abstract：OBJECTIVES:The aim of this study was to compare the palatal total support tissues (TSTs) and bone support tissues (BSTs) at 5-mm paramedian section to the midsagittal suture between mouth breathers with high-narrow palates and nose breathers with normal palates and confirm the practicability and limitation on superimpo...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-019-03004-w
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to quantify the symmetry of the alveolar process of the maxilla and palate during the first year of life in healthy infants with the help of a semiautomatic segmentation technique. MATERIALS AND METHODS:Maxillary plaster models of seventy healthy babies at 0, 3, 6, 9, and 12 mo...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03403-4
更新日期：2020-06-24 00:00:00
abstract：OBJECTIVES:To evaluate the diagnostic efficacy of CBCT-MRI fused images for articular disc calcification of temporomandibular joint (TMJ). MATERIALS AND METHODS:Twenty patients (24 TMJs) whose image examinations showed dense bodies in the TMJ space were included in the study. The locations of dense bodies evaluated by...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03497-w
更新日期：2020-08-12 00:00:00
abstract：OBJECTIVES:Most patients with bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) report a previous tooth extraction at the necrosis site before the diagnosis was made. At older ages, most teeth are extracted due to periodontal disease, which is per se another BP-ONJ trigger factor. The aim of this study was t...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-013-0974-7
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:The aim of this investigation was to assess the currently available evidence concerning the complications and risk factors influencing the outcome of autotransplantation of teeth in humans. MATERIALS AND METHODS:Electronic searches were conducted to identify randomized controlled and prospective clinical tr...
journal_title：Clinical oral investigations
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00784-015-1473-9
更新日期：2015-07-01 00:00:00
abstract：:This study evaluated by standardised digitised periapical radiography the crestal bone maintenance around modified diameter internal hex implants with variable thread design and narrow neck loaded with different procedures. Forty implants were placed in 25 patients. Twenty implants were conventionally loaded, 20 ones ...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-009-0314-0
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVES:Τhis study aims at determining the ability of cone beam computed tomography (CBCT) to visualize critical-size defects (CSD) created at rat calvaria and filled with 75/25 w/w nano-hydroxyapatite/chitosan (nHAp/CS) scaffolds, prior to their histological investigation. MATERIALS AND METHODS:Thirty adult Spragu...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-019-02939-4
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVES:This systematic review (SR) aimed to summarise and critically appraise available evidence about the association between the synergistic consumption of alcohol and tobacco and the occurrence of oral squamous cell carcinoma (OSCC). MATERIALS AND METHODS:Observational studies investigating the association betw...
journal_title：Clinical oral investigations
pub_type： 杂志文章,meta分析
doi：10.1007/s00784-019-02958-1
更新日期：2019-07-01 00:00:00
abstract：:The purpose of this study was to determine the risk of microbiological transmission into the dental laboratory via impressions and dental stone models. Metal master models were contaminated with Bacillus subtilis and Streptococcus sanguis. Impressions in alginate, polyvinylsiloxane, and polyether were used, and models...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-002-0174-3
更新日期：2002-09-01 00:00:00
abstract：INTRODUCTION:Decay of teeth, erosion and disintegration of hard dental tissue are a clinically often seen side effect after radiotherapy for tumours in the head and neck region. To investigate if these side effects are due to structural changes in dental hard tissues, the current literature was searched. It can influen...
journal_title：Clinical oral investigations
pub_type： 杂志文章,评审
doi：10.1007/s00784-013-1034-z
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:Sialolithiasis is the most common cause of chronic sialadenitis of the submandibular gland (SMG). Symptomatic superficial lobe stones are often treated by submandibulectomy. A gland preserving operation allows for transoral stone removal through endoscopically assisted sialolithotomy. Herein, we provide clin...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-019-02853-9
更新日期：2019-11-01 00:00:00
abstract：:This paper presents a short review of three groups of tools which can be or are used for the tissue engineering of mineralized oral structures: growth factor delivery systems (GFDS) and surface bioactivation with covalent bound peptides or with nanomechanically linked proteins. According to the reported personal exper...
journal_title：Clinical oral investigations
pub_type： 杂志文章,评审
doi：10.1007/s007840050128
更新日期：2000-06-01 00:00:00
abstract：:The aim of this study was to evaluate the influence of caries-detecting dyes on the microleakage of adhesive materials. Sixty cubic class V cavities were prepared on buccal and lingual surfaces of 30 human third molars. Coronal margins were located in enamel and gingival margins in cementum. The teeth were randomly di...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-002-0182-3
更新日期：2002-12-01 00:00:00
abstract：OBJECTIVES:The aim of this study is to investigate the relationship between periodontal morphometric parameters and to develop a biotype classification based on the variables examined with the use of cone-beam computed tomography (CBCT). MATERIALS AND METHODS:Forty-two periodontally healthy subjects that underwent a C...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1694-y
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVES:Intermittent parathyroid hormone (PTH) exerts anabolic effects on bone and has been approved for osteoporosis therapy. The dual actions of PTH are mediated primarily through the parathyroid hormone 1 receptor (PTH1R). Upon ligand binding, PTH1R activates diverse signaling pathways, including cAMP/protein kin...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-013-0985-4
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:It is well accepted that stage-specific embryonic antigen (SSEA)-4 is an antigen that is useful to isolate adult stem cells analogous to embryonic stem cells. Therefore, in the present study, we investigated whether SSEA-4 can also be used as a marker to identify human deciduous dental pulp (D-DP) stem cells...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-014-1260-z
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to evaluate the effect of different seating forces during cementation in cement-ceramic microtensile bond strength (μTBS). MATERIALS AND METHODS:Forty-five blocks (5 × 5 × 4 mm(3)) of a glass-infiltrated alumina-based ceramic (In-Ceram Alumina) were fabricated according to the manu...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-011-0668-y
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVES:BioAggregate™ is a novel material introduced for use as a root-end filling material. It is tricalcium silicate-based, free of aluminium and uses tantalum oxide as radiopacifier. BioAggregate contains additives to enhance the material performance. The purpose of this research was to characterize the un-hydrat...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-014-1292-4
更新日期：2015-04-01 00:00:00
abstract：OBJECTIVES:Facial asymmetries in oculoauriculovertebral spectrum (OAVS) patients might require surgical corrections that are mostly based on qualitative approach and surgeon's experience. The present study aimed to develop a quantitative 3D CT imaging-based procedure suitable for maxillo-facial surgery planning in OAVS...
journal_title：Clinical oral investigations
pub_type： 杂志文章,评审
doi：10.1007/s00784-015-1660-8
更新日期：2016-03-01 00:00:00
abstract：:The present study examines the three-dimensional (3D) morphology of early approximal subsurface enamel caries lesions and subjacent dentin reactions in deciduous molars. Twenty-three extracted primary molars were embedded in Technovit 9100 and serial sections were cut using a saw microtome. Forty approximal lesions we...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s007840050066
更新日期：1998-12-01 00:00:00
abstract：:The use of the vascularized fibula graft has already been established for reconstruction of the mandible following ablative surgery. In order to reconstruct the vertical height of the alveolar process and improve implant position as well as angulation, some therapeutic options are available, including primary use of t...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-011-0582-3
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVES:The aim of the meta-analysis was to clarify the efficacy of non-surgical periodontal treatment (NSPT) in improving rheumatoid arthritis (RA) disease activity. METHODS:A systematic literature search was conducted using the PubMed, Embase, and Cochrane databases up to October 2020. A total of nine studies wer...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-021-03807-w
更新日期：2021-01-29 00:00:00
