Abstract:
:The effect of fluoride released by bioadhesive tablets was evaluated in an in situ model in human volunteers. Eight volunteers carried four to six polished human enamel samples in a lower lingual device for a period of 5 days without fluoride supplements (control) and 5 days using one bioadhesive tablet (0.5 mg F) per day, placed in the lower buccal sulcus. Changes in mineral content were measured in terms of surface microhardness indentation length (load 0.98 N, Knoop diamond indenter). Some enamel samples were analyzed for their fluoride content by means of a surface etch biopsy. The indentation length increased significantly in both experiments, but demineralization was less pronounced with fluoride (indentation length increased from 44 +/- 7 to 48 +/- 13 microns) than in the control (44 +/- 7 to 58 +/- 13 microns). The fluoride concentration and the amount of calcium in the acid etch biopsy specimens of the enamel samples did not differ significantly between the two groups. Bioadhesive, fluoride-releasing tablets have therefore demonstrated the potential to reduce demineralization by elevating salivary and plaque fluoride concentration for a period of several hours. This self-administered device can be a supplementary means for prevention of caries.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Bottenberg P,Cleymaet R,Röhrkasten K,Lampert Fdoi
10.1007/s007840000076keywords:
subject
Has Abstractpub_date
2000-09-01 00:00:00pages
153-6issue
3eissn
1432-6981issn
1436-3771journal_volume
4pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVES:To explore whether a computed tomography (CT) examination of the head and neck region induces biological damage and whether the damage was correlated with the radiation dose. MATERIALS AND METHODS:Peripheral blood was taken from 33 individuals who received head and neck CT examinations. Blood samples were d...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03331-3
更新日期:2020-12-01 00:00:00
abstract::The aim of this study was to compare detection of non-cavitated approximal caries lesions in images from seven solid-state intraoral digital receptors, with particular focus on two task-specific enhancement filters. One hundred and sixty approximal non-cavitated surfaces were radiographed under standardized conditions...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-007-0173-5
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVES:Facial asymmetries in oculoauriculovertebral spectrum (OAVS) patients might require surgical corrections that are mostly based on qualitative approach and surgeon's experience. The present study aimed to develop a quantitative 3D CT imaging-based procedure suitable for maxillo-facial surgery planning in OAVS...
journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s00784-015-1660-8
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:This study aimed to evaluate and correlate the efficacy and cytotoxicity of a 35 % hydrogen peroxide (HP) bleaching gel after different application times on dental enamel. MATERIALS AND METHODS:Enamel/dentin disks in artificial pulp chambers were placed in wells containing culture medium. The following grou...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0883-1
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:Stud attachments are often too adhesive and too susceptible to damage for use in geriatric patients, especially when implants are angulated. This study aimed to evaluate alternative anchoring systems comprising individual and prefabricated polyvinylsiloxane (PVS) attachments. MATERIALS AND METHODS:A total o...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2568-x
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:The aim of this study is to investigate the relationship between periodontal morphometric parameters and to develop a biotype classification based on the variables examined with the use of cone-beam computed tomography (CBCT). MATERIALS AND METHODS:Forty-two periodontally healthy subjects that underwent a C...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1694-y
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:Postoperative pain management is of highest interest for patients undergoing maxillofacial surgery including microvascular reconstructive surgery. Currently, there is a lack of information regarding process and outcome of postoperative pain management after microvascular reconstruction. MATERIALS AND METHOD...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1809-0
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:It was the aim of the study to analyse the prevalence of maxillofacial trauma (MFT) in severely injured patients after road traffic accidence (RTA) and to investigate associated factors. MATERIALS AND METHODS:In a retrospective study, data from patients after RTA by the TraumaRegister DGU® from 1993 to 2014...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03024-6
更新日期:2020-01-01 00:00:00
abstract::The purpose of this study was to test the hypothesis of multidimensionality of oral and general health behaviour. To evaluate the proposed behavioural dimensions, relationships with individual beliefs and socio-economic factors were explored. A simple random sample of 1190 residents born in 1972 was drawn from the pop...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840000102
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVE:SLC22A4/5 single nucleotide polymorphisms (SNPs) have been reported to affect inflammatory diseases. We report the relationship of these polymorphisms with adiposity and tooth loss as elucidated in a 10-year follow-up study. METHODS:Participants of the Study of Health in Pomerania (SHIP, N = 4105) were genot...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03594-w
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVES:The present study evaluated the effect of an enamel matrix derivative (EMD) and platelet-rich fibrin (PRF)-modified porcine-derived collagen matrix (PDCM) on human umbilical vein endothelial cells (HUVEC) in vitro. MATERIALS AND METHODS:PDCM (mucoderm®) was prepared to 6 mm (±0.1 mm) diameter discs. PDCM sa...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2170-7
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:This study aimed to assess self- and proxy-rated changes in the oral health-related quality of life (OHRQoL) in adult patients with intellectual disabilities after dental treatment in general anesthesia. METHODS:The OHRQoL in 52 adult patients with intellectual and developmental disabilities was assessed pr...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02820-4
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:The use of the autogenous periosteal graft as biological barrier has been proposed for periodontal regeneration. The aim of this study was to evaluate the histometric findings of the subepithelial connective tissue graft as barrier in intrabony defects compared to a bioabsorbable membrane. METHODS:Three-wal...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1323-1
更新日期:2015-06-01 00:00:00
abstract::The alveolar cleft in patients with clefts of lip, alveolus and palate (CLAP) is usually reconstructed with an autologous bone graft. Harvesting of autologous bone grafts is associated with more or less donor site morbidity. Donor site morbidity could be eliminated if bone is fabricated by growth factor-aided tissue e...
journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s00784-011-0547-6
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:A group of adolescents with oral piercings was studied to determine the presence of metallic particles in cells exfoliated from the mucosa surrounding their metal oral piercings and the association between such particles and the metal jewelry, and to evaluate subsequent tissue implications. MATERIALS AND ME...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2626-4
更新日期:2019-04-01 00:00:00
abstract::Recently, resin-based dental restorative materials have been targeted as potential sources of xenoestrogens, specifically bisphenol A (BPA) and bisphenol A dimethacrylate (BAD), which could contribute to overall estrogen load and result in deleterious side effects. The present study used high-pressure liquid chromatog...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840050087
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the chemokine expression profiles in gingival crevicular fluid (GCF) and serum in patients with advanced chronic periodontitis and to assess the impact of smoking on local and systemic levels of chemokines. MATERIALS AND METHODS:Thirty patients with chronic periodonti...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1314-2
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to evaluate and compare the osteoblastic differentiation ability of dedifferentiated fat (DFAT) cells and adipose stem cells (ASCs) from the buccal fat pad (BFP). MATERIALS AND METHODS:We isolated human DFAT cells and ASCs from the BFP of a patient who underwent oral and maxill...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1166-1
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:The aims of this study were to investigate the antimicrobial efficacy of antiseptics in saliva-derived microcosm biofilms, and to examine phenotypic adaption of bacteria upon repeated exposure to sub-inhibitory antiseptic concentrations. METHODS:Saliva-derived biofilms were formed mimicking caries- or gingi...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03613-w
更新日期:2020-10-08 00:00:00
abstract:OBJECTIVE:The aim of this in vitro study was to compare fluorescence-aided caries excavation with conventional excavation based on the Martens and Vickers hardness of dentin at the cavity floor after caries removal. MATERIALS AND METHODS:In total, 20 extracted human teeth with dentin caries were bisected through the l...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-0999-y
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to introduce a novel three-dimensional (3D) method to quantify the relative amount of different tissue components in bone substitute-treated defects by means of integration of confocal laser imaging into micro-computed tomography (μCT) analysis. MATERIALS AND METHODS:One standardize...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1081-5
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:The aim of this article is to compare the influence of surface treatment on the integration (at 2, 4 and 8 weeks) of 120 dental implants inserted in 60 tibiae of rabbits. MATERIALS AND METHODS:Four different surfaces were double-blind tested: blasted, acid-etched and discrete crystal deposition (DCD) (group ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1241-2
更新日期:2015-03-01 00:00:00
abstract:INTRODUCTION:To compare, by Micro-CT and confocal laser scanning microscopy (CLSM), the ability of the Wave One Gold and Wave One systems to remove filling material from mesial canals of mandibular molars, effective time spent; quantity of extruded material, and percentage of sealer in the dentinal tubules after retrea...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2441-y
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:The present longitudinal study aimed to compare changes in the lower third molar position and nerve involvement in orthodontically treated patients with and without premolar extractions. MATERIALS AND METHODS:The sample consisted of pretreatment and posttreatment panoramic radiographs of 349 orthodontically...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1148-3
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the contamination level of toothbrushes by mutans streptococci (MS) and the efficacy of antimicrobial solutions: cetylpyridinium chloride 0.05 % (CPC; Cepacol™) and chlorhexidine 0.12 % (CHX; Periogard™), to disinfect toothbrushes of preschool-aged children in day-care centers. MATERIAL AND METHO...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-013-1169-y
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:To assess the quality of clinical practice guidelines (CPGs) on screening and diagnosis of oral cancer and to describe the characteristics of their recommendations. MATERIALS AND METHODS:We systematically searched EMBASE, MEDLINE, CPG' websites, and dentistry and oncology scientific societies to identify CP...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2668-7
更新日期:2019-05-01 00:00:00
abstract::The objective of this study is to evaluate flexural strength, flexural modulus, compressive strength, curing temperature, curing depth, volumetric shrinkage, water sorption, and hygroscopic expansion of two self-, three dual-, and three light-curing resin-based core materials. Flexural strength and water sorption were...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-010-0405-y
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the periodontal healing pattern of dehiscence-type defects following different chemical root conditioning modalities. MATERIALS AND METHODS:Buccal osseous dehiscence defects were created on six teeth of seven dogs. After dental plaque accumulation, defects were tr...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0848-4
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVES:In this single-blinded, prospective, randomized, controlled clinical trial, the effectiveness of an ozone gas or NaOCl/CHX disinfection protocol was compared within the root canal treatment of apical periodontitis. MATERIALS AND METHODS:Sixty permanent teeth were randomly allocated to one technique. The cli...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-016-1849-5
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:Cell-free DNA (cfDNA) harboring mutations has been found in patients with diseases. Experimental studies have shown that cfDNA can be transmitted, leading to transformations in the host. In the present study, we evaluated whether bone allograft material contains cfDNA and whether this foreign cfDNA can be re...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02867-3
更新日期:2019-12-01 00:00:00