当前位置： SCI文献检索 > Clinical Oral Investigations期刊下所有文献 > Impact of periodontitis on chemokines in smokers.

Impact of periodontitis on chemokines in smokers.

Abstract：

OBJECTIVE:The aim of this study was to investigate the chemokine expression profiles in gingival crevicular fluid (GCF) and serum in patients with advanced chronic periodontitis and to assess the impact of smoking on local and systemic levels of chemokines. MATERIALS AND METHODS:Thirty patients with chronic periodontitis (CP; 20 smokers and 10 non-smokers) and 20 periodontally healthy subjects (10 smokers and 10 non-smokers) were recruited. Clinical parameters included the plaque index (PI), gingival index (GI), and bleeding on probing (BOP). Macrophage inflammatory protein-1 alpha (MIP-1α), macrophage inflammatory protein-1 beta (MIP-1β), monocyte chemoattractant protein-1 (MCP-1), and regulated on activation normal T cell expressed and secreted chemokine (RANTES) were measured in gingival crevicular fluid (GCF) and serum using a multiplex immunoassay. RESULTS:MIP-1α levels were significantly lower (10.15 ± 1.48; p = 0.039) while MIP-1β levels were significantly higher (42.05 ± 8.21; p = 0.005) in sera from non-smoker patients with CP compared to non-smoker healthy subjects. MCP-1 concentration in sera was significantly higher in smoker periodontitis patients (8.89 ± 1.65) compared to non-smoker patients with periodontitis (8.14 ± 0.97; p = 0.004). MIP-1α and RANTES were significantly higher in GCF of the patients with CP (p = 0.001) while there were no statistically significant correlations between the GCF levels of these analytes and the smoking status. CONCLUSION:Periodontal inflammation increases the chemokine concentrations in the GCF while smoking suppresses chemokine levels in serum suggesting that different local and systemic mechanisms are involved during the response to periodontitis in smokers. CLINICAL RELEVANCE:Understanding the local and systemic chemokine responses in smokers will enable the development of biologically-based treatment methods for chronic periodontitis.

journal_name

Clin Oral Investig

journal_title

Clinical oral investigations

authors

Haytural O,Yaman D,Ural EC,Kantarci A,Demirel K

doi

10.1007/s00784-014-1314-2

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

979-86

issue

5

eissn

1432-6981

issn

1436-3771

journal_volume

19

pub_type

杂志文章

相关文献

Clinical Oral Investigations文献大全
  • Levobupivacaine vs. bupivacaine for third molar surgery: quality of anaesthesia, postoperative analgesia and local vascular effects.

    abstract：OBJECTIVES:The main purpose of this prospective, double-blind, randomized study was to evaluate anaesthetic parameters, postoperative analgesia and vasoactive properties of levobupivacaine and bupivacaine for lower third molar surgery. MATERIAL AND METHODS:Sixty patients (ASA I) were scheduled for lower third molar su...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-013-1114-0

    authors： Brajkovic D,Brkovic B,Milic M,Biocanin V,Krsljak E,Stojic D

    更新日期：2014-01-01 00:00:00

  • CXCL1, CCL2, and CCL5 modulation by microbial and biomechanical signals in periodontal cells and tissues-in vitro and in vivo studies.

    abstract：OBJECTIVES:This study was established to investigate whether the chemokines CXCL1, CCL2, and CCL5 are produced in periodontal cells and tissues and, if so, whether their levels are regulated by microbial and/or mechanical signals. MATERIALS AND METHODS:The chemokine expression and protein levels in gingival biopsies f...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-020-03244-1

    authors： Rath-Deschner B,Memmert S,Damanaki A,Nokhbehsaim M,Eick S,Cirelli JA,Götz W,Deschner J,Jäger A,Nogueira AVB

    更新日期：2020-10-01 00:00:00

  • Dyes for caries detection: influence on composite and compomer microleakage.

    abstract：:The aim of this study was to evaluate the influence of caries-detecting dyes on the microleakage of adhesive materials. Sixty cubic class V cavities were prepared on buccal and lingual surfaces of 30 human third molars. Coronal margins were located in enamel and gingival margins in cementum. The teeth were randomly di...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-002-0182-3

    authors： Piva E,Meinhardt L,Demarco FF,Powers JM

    更新日期：2002-12-01 00:00:00

  • Experimental peri-implantitis around titanium implants with a chemically modified surface with a monolayer of multi-phosphonate molecules: a preclinical in vivo investigation.

    abstract：OBJECTIVES:The purpose of this experimental in vivo investigation was to evaluate the influence of modifying the implant surface by adding a monolayer of multi-phosphonate molecules on the development of experimental peri-implantitis. MATERIAL AND METHODS:Eight beagle dogs received 5 tests and 5 control implants each ...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-020-03708-4

    authors： Sanz-Esporrin J,Di Raimondo R,Pla R,Luengo F,Vignoletti F,Núñez J,Antonoglou GJ,Blanco J,Sanz M

    更新日期：2021-01-06 00:00:00

  • Effect of gastric acids on surface topography and bending properties of esthetic coated nickel-titanium orthodontic archwires.

    abstract：OBJECTIVE:The purpose of this study was to evaluate the effect of simulated gastric acid solution on surface topography and bending properties of esthetic coated nickel-titanium (NiTi) archwires. MATERIALS AND METHODS:Three brands of as-received white-coated superelastic NiTi upper archwires were used in this study: D...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-020-03438-7

    authors： Elsaka S,Hassan A,Elnaghy A

    更新日期：2020-07-03 00:00:00

  • DNA double-strand breaks of human peripheral blood lymphocyte induced by CT examination of oral and maxillofacial region.

    abstract：OBJECTIVES:To explore whether a computed tomography (CT) examination of the head and neck region induces biological damage and whether the damage was correlated with the radiation dose. MATERIALS AND METHODS:Peripheral blood was taken from 33 individuals who received head and neck CT examinations. Blood samples were d...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-020-03331-3

    authors： Yang P,Wang S,Liu D,Zhao H,Li G

    更新日期：2020-12-01 00:00:00

  • Reduced CD8+ T cells infiltration can be associated to a malignant transformation in potentially malignant oral epithelial lesions.

    abstract：OBJECTIVE:The aim of this study was to evaluate the immunohistochemical expressions of PD1, CD4+, and CD8+ in premalignant lesions (OPML) that were transformed into oral squamous cell carcinoma OSCC (OPML-OSCC), in OSCC and also in premalignant lesions that were not transformed into OSCC (OPML-NOSSC). MATERIALS AND ME...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-018-2622-8

    authors： Chaves ALF,Silva AG,Maia FM,Lopes GFM,de Paulo LFB,Muniz LV,Dos Santos HB,Soares JMA,Souza AA,de Oliveira Barbosa LA,Loyola AM,Murta EFC,Michelin MA,de Azambuja Ribeiro RIM

    更新日期：2019-04-01 00:00:00

  • The effect of glass ionomer cement or composite resin bases on restoration of cuspal stiffness of endodontically treated premolars in vitro.

    abstract：:The purpose of the present study was to decide whether composite resin or conventional glass ionomer cement should be preferred as a base material in endodontically treated premolars. Twelve extracted human maxillary premolars were mounted in a universal testing machine at a 35 degrees angle. Cuspal stiffness was dete...

    journal_title：Clinical oral investigations

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/s007840050049

    authors： Hofmann N,Just N,Haller B,Hugo B,Klaiber B

    更新日期：1998-06-01 00:00:00

  • A novel three-dimensional analysis of standardized bone defects by means of confocal scanner and micro-computed tomography.

    abstract：OBJECTIVES:The aim of the study was to introduce a novel three-dimensional (3D) method to quantify the relative amount of different tissue components in bone substitute-treated defects by means of integration of confocal laser imaging into micro-computed tomography (μCT) analysis. MATERIALS AND METHODS:One standardize...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-013-1081-5

    authors： Clozza E,Obrecht M,Dard M,Coelho PG,Dahlin C,Engebretson SP

    更新日期：2014-05-01 00:00:00

  • Orthodontic cell stress modifies proinflammatory cytokine expression in human PDL cells and induces immunomodulatory effects via TLR-4 signaling in vitro.

    abstract：OBJECTIVE:Biomechanical orthodontics loading of the periodontium initiates a cascade of inflammatory signaling events that induce periodontal remodeling and finally facilitate orthodontic tooth movement. Pattern recognition receptors such as toll-like receptors (TLRs) have been well characterized for their ability to i...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-019-03111-8

    authors： Marciniak J,Lossdörfer S,Knaup I,Bastian A,Craveiro RB,Jäger A,Wolf M

    更新日期：2020-04-01 00:00:00

  • The association with xerostomia from sialadenitis and the jaw osteonecrosis in head and neck cancer population: a nationwide cohort study.

    abstract：OBJECTIVES:Determine the association between sialadenitis and osteonecrosis of the jaw (ONJ) in head and neck cancer (HNC) patients with varying severity of sialadenitis, treatment modalities, and cancer locations. MATERIALS AND METHODS:A total of 40,168 HNC patients, including 1907 ONJ subjects and 7559 matched compa...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-018-2465-3

    authors： Huang YF,Muo CH,Tsai CH,Liu SP,Chang CT

    更新日期：2019-02-01 00:00:00

  • Diagnostic performance of the universal visual scoring system (UniViSS) on occlusal surfaces.

    abstract：:Aim of this investigation was to evaluate the validity and reproducibility of the universal visual scoring systems (UniViSS) on occlusal surfaces in vitro. The validity study included 65 third molars. Following to reach a UniViSS consensus diagnosis for each surface, all teeth were histologically prepared and evaluate...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-010-0390-1

    authors： Kühnisch J,Bücher K,Henschel V,Albrecht A,Garcia-Godoy F,Mansmann U,Hickel R,Heinrich-Weltzien R

    更新日期：2011-04-01 00:00:00

  • Comparing the effects of three different fluoride-releasing agents on white spot lesion prevention in patients treated with full coverage rapid maxillary expanders.

    abstract：OBJECTIVE:The aim of this study was to assess the effects of three different fluoride-releasing agents on preventing white spot lesions that occur during treatment with full coverage rapid maxillary expanders. MATERIALS AND METHODS:A total of 48 patients with transverse maxillary deficiency were randomly assigned to f...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-018-2749-7

    authors： Korkmaz YN,Yagci A

    更新日期：2019-08-01 00:00:00

  • Re: Does smoking habit increase the micronuclei frequency in the oral mucosa of adults compared to non-smokers? A systematic review and meta-analysis. de Geus et al., Clin Oral Investig. 2018 Jan; 22(1):81-91.

    abstract：: ...

    journal_title：Clinical oral investigations

    pub_type： 评论,信件

    doi：10.1007/s00784-018-2788-0

    authors： Nersesyan A

    更新日期：2019-01-01 00:00:00

  • Limited antimicrobial efficacy of oral care antiseptics in microcosm biofilms and phenotypic adaptation of bacteria upon repeated exposure.

    abstract：OBJECTIVES:The aims of this study were to investigate the antimicrobial efficacy of antiseptics in saliva-derived microcosm biofilms, and to examine phenotypic adaption of bacteria upon repeated exposure to sub-inhibitory antiseptic concentrations. METHODS:Saliva-derived biofilms were formed mimicking caries- or gingi...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-020-03613-w

    authors： Schwarz SR,Hirsch S,Hiergeist A,Kirschneck C,Muehler D,Hiller KA,Maisch T,Al-Ahmad A,Gessner A,Buchalla W,Cieplik F

    更新日期：2020-10-08 00:00:00

  • Coronal and apical lesions, environmental factors: study in a modern and an archeological population.

    abstract：:Apical periodontitis (AP) are frequent findings in contemporary dental practice in association with dental pathology or dental care. They have also been studied from an anthropological background. The purpose of this study was to compare the prevalence of apical and dental lesions in an archeological Middle Ages sampl...

    journal_title：Clinical oral investigations

    pub_type： 历史文章,杂志文章

    doi：10.1007/s00784-005-0318-3

    authors： Chazel JC,Valcarcel J,Tramini P,Pelissier B,Mafart B

    更新日期：2005-09-01 00:00:00

  • Methodological considerations concerning the development of oral dental erosion indexes: literature survey, validity and reliability.

    abstract：:Within the context of preventing non-communicable diseases, the World Health Report (2002) and the WHO Global Oral Health Program (2003) put forward a new strategy of disease prevention and health promotion. Greater emphasis is placed on developing global policies in oral health promotion and oral disease prevention. ...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章,评审

    doi：10.1007/s00784-007-0178-0

    authors： Berg-Beckhoff G,Kutschmann M,Bardehle D

    更新日期：2008-03-01 00:00:00

  • Oral rehabilitation with dental implants and quality of life following mandibular reconstruction with free fibular flap.

    abstract：OBJECTIVES:Bony reconstruction of jaw defects using the free fibular flap and dental rehabilitation mostly requires insertion of dental implants within the transferred fibula bone. The aim of this paper was to discuss results of the implant stability with data on the possible benefit for the patient's quality of life a...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-015-1487-3

    authors： Jacobsen HC,Wahnschaff F,Trenkle T,Sieg P,Hakim SG

    更新日期：2016-01-01 00:00:00

  • Material selection for tooth-supported single crowns-a survey among dentists in Germany.

    abstract：OBJECTIVES:This study aimed to survey dentists in Germany to identify their favored materials for the fabrication of tooth-supported single crowns (SCs) depending on the location of the abutment teeth and the preparation margin. MATERIALS AND METHODS:The survey included questions regarding demographic characteristics ...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-020-03363-9

    authors： Rauch A,Schrock A,Schierz O,Hahnel S

    更新日期：2021-01-01 00:00:00

  • Association between patient satisfaction with complete dentures and oral health-related quality of life: two-year longitudinal assessment.

    abstract：:The objective was to evaluate the development of oral health-related quality of life (OHRQoL) in patients with complete dentures and the association between OHRQoL and patient satisfaction. Fifty-two patients (mean age, 66.3, 48.1% male) received dentures in at least one jaw. The analysis was conducted on participants...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-010-0483-x

    authors： Stober T,Danner D,Lehmann F,Séché AC,Rammelsberg P,Hassel AJ

    更新日期：2012-02-01 00:00:00

  • Reconstruction of the alveolar cleft: can growth factor-aided tissue engineering replace autologous bone grafting? A literature review and systematic review of results obtained with bone morphogenetic protein-2.

    abstract：:The alveolar cleft in patients with clefts of lip, alveolus and palate (CLAP) is usually reconstructed with an autologous bone graft. Harvesting of autologous bone grafts is associated with more or less donor site morbidity. Donor site morbidity could be eliminated if bone is fabricated by growth factor-aided tissue e...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章,评审

    doi：10.1007/s00784-011-0547-6

    authors： van Hout WM,Mink van der Molen AB,Breugem CC,Koole R,Van Cann EM

    更新日期：2011-06-01 00:00:00

  • Competing interplay between systemic and periodontal inflammation: obesity overrides the impact of oral periphery.

    abstract：OBJECTIVES:We aimed at investigating whether the interaction between the local inflammation, periodontitis, and obesity is independently associated with systemic inflammation. METHODS:From the population-based Study of Health in Pomerania, 3366 participants, without (2366) and with (1000) obesity, were studied for the...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-020-03514-y

    authors： Meisel P,Pink C,Pitchika V,Nauck M,Völzke H,Kocher T

    更新日期：2020-08-22 00:00:00

  • Impact of the intraoral location on the rate of biofilm growth.

    abstract：:The aims of the present study were: a) to assess the impact of the intraoral location on the rate of biofilm growth, and b) to establish an in vivo biofilm model to examine intraoral biofilm growth. Eight healthy volunteers wore acrylic splints with 15 glass slabs each in the upper and lower jaws to build up plaque. A...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-004-0255-6

    authors： Auschill TM,Hellwig E,Sculean A,Hein N,Arweiler NB

    更新日期：2004-06-01 00:00:00

  • Root groove depth and inter-orifice canal distance as anatomical predictive factors for danger zone in the mesial root of mandibular first molars.

    abstract：OBJECTIVES:This study evaluated the danger zone (DZ) in mesial roots of mandibular molars and the correlation between anatomical references of the DZ and some anatomical landmarks including tooth/root length, depth of mesial and distal grooves, and inter-canal orifices distance. MATERIAL AND METHODS:Twenty-eight mesia...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-020-03686-7

    authors： De-Deus G,Rodrigues EA,Lee JK,Kim J,da Silva EJNL,Belladonna FG,Cavalcante DM,Simões-Carvalho M,Oliveira DDS,Versiani MA,Souza EM

    更新日期：2020-11-24 00:00:00

  • The eligibility of the free fibula graft for masticatory rehabilitation using monocortical implants insertion--a morphologic and biomechanical study.

    abstract：:The use of the vascularized fibula graft has already been established for reconstruction of the mandible following ablative surgery. In order to reconstruct the vertical height of the alveolar process and improve implant position as well as angulation, some therapeutic options are available, including primary use of t...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-011-0582-3

    authors： Hakim SG,Jeske G,Jacobsen HC,Sieg P

    更新日期：2012-04-01 00:00:00

  • Outcome of secondary root canal treatment filled with Thermafil: a 5-year follow-up of retrospective cohort study.

    abstract：OBJECTIVES:The aim of the present retrospective cohort study was to assess the 5-year outcome and survival of secondary root canal treatments (2°RCT), exploring the influence of pre-, intra-, and post-operative variables. MATERIALS AND METHODS:One hundred thirty-two endodontically retreated teeth were radiographically...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-017-2229-5

    authors： Pirani C,Iacono F,Gatto MR,Fitzgibbon RM,Chersoni S,Shemesh H,Prati C

    更新日期：2018-04-01 00:00:00

  • TGF-βRI kinase activity mediates Emdogain-stimulated in vitro osteoclastogenesis.

    abstract：OBJECTIVES:Emdogain, containing an extract of fetal porcine enamel matrix proteins, is a potent stimulator of in vitro osteoclastogenesis. The underlying molecular mechanisms are, however, unclear. MATERIAL AND METHODS:Here, we have addressed the role of transforming growth factor-beta receptor type 1 (TGF-βRI) kinase...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-013-1129-6

    authors： Gruber R,Roos G,Caballé-Serrano J,Miron R,Bosshardt DD,Sculean A

    更新日期：2014-07-01 00:00:00

  • Masticatory rehabilitation following upper and lower jaw reconstruction using vascularised free fibula flap and enossal implants-19 years of experience with a comprehensive concept.

    abstract：OBJECTIVES:Conventional prosthesis is generally inapplicable following reconstruction with free fibula flaps (FFF) due to impaired bone and soft tissue conditions, and rehabilitation via enossal implants in FFF is relatively novel. This retrospective study aimed to document the surgical aspects of this option and to de...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-014-1247-9

    authors： Hakim SG,Kimmerle H,Trenkle T,Sieg P,Jacobsen HC

    更新日期：2015-03-01 00:00:00

  • No deficit in neurocortical information processing in patients with cleft lip and palate.

    abstract：BACKGROUND:Cleft lip and palate (CLP) represents the most common malformation of the midfacial region worldwide. It can be suggested that the facial stigmatization, the speech impediment, and the long-standing pressure of treatment cause a range of life stressors. Neurocortical information is influenced by physiologica...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-015-1465-9

    authors： Gassling V,Receveur K,Niederberger U,Koos B,Overath CH,Birkenfeld F,Wiltfang J,Gerber WD,Siniatchkin M

    更新日期：2016-01-01 00:00:00

  • Selective vs stepwise removal of deep carious lesions in primary molars: 24 months follow-up from a randomized controlled trial.

    abstract：OBJECTIVES:For well-defined deep (> 2/3 dentin extension) carious lesions, selective (SE) or stepwise (SW) carious tissue removals have been recommended, while there is limited comparative evidence for both. We compared SE and SW over 24 months in a randomized controlled trial. METHODS:A two-arm superiority trial was ...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s00784-020-03536-6

    authors： Elhennawy K,Finke C,Paris S,Reda S,Jost-Brinkmann PG,Schwendicke F

    更新日期：2021-02-01 00:00:00