Abstract：
OBJECTIVES:We aimed at investigating whether the interaction between the local inflammation, periodontitis, and obesity is independently associated with systemic inflammation. METHODS:From the population-based Study of Health in Pomerania, 3366 participants, without (2366) and with (1000) obesity, were studied for the association of periodontitis, measured as probing depth (PD) and plaque together with body mass index (BMI) on C-reactive protein (CRP). Quantile regression was used to evaluate the association between periodontal, anthropometric, and inflammatory variables (outcomes). RESULTS:The overall prevalence of obesity in this adult population was 31.4% in men and 28.1% in women. Both PD and plaque were positively associated with CRP, revealing an increasing impact across the CRP concentration distribution. Adjusting the regression of CRP or fibrinogen on PD for waist circumference attenuated but did not abolish the PD coefficients. Dental plaque was similarly associated with these interrelations. Association between PD and a dental plaque was different among participants with low-, medium-, or high-risk CRP concentrations. CONCLUSION:Local and systemic sources of inflammation contribute to blood levels of inflammatory markers. The respective contributions depend on the relative rate in each of the inflammation-inducing risks and are dominated by adiposity. CLINICAL RELEVANCE:Keeping systemic inflammation low in order to prevent age-related disease sequelae.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Meisel P,Pink C,Pitchika V,Nauck M,Völzke H,Kocher Tdoi
10.1007/s00784-020-03514-ysubject
Has Abstractpub_date
2020-08-22 00:00:00eissn
1432-6981issn
1436-3771pii
10.1007/s00784-020-03514-ypub_type
杂志文章abstract：:The use of the vascularized fibula graft has already been established for reconstruction of the mandible following ablative surgery. In order to reconstruct the vertical height of the alveolar process and improve implant position as well as angulation, some therapeutic options are available, including primary use of t...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-011-0582-3
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVES:The purpose of this prospective clinical trial was to examine the clinical and patient outcomes following esthetic reconstruction of interdental papilla loss in anterior teeth, using an injectable, non-animal-based, hyaluronic acid gel. MATERIALS AND METHODS:Ten systemically healthy adults, with at least on...
journal_title：Clinical oral investigations
pub_type： 临床试验,杂志文章
doi：10.1007/s00784-015-1677-z
更新日期：2016-09-01 00:00:00
abstract：:Apical periodontitis (AP) are frequent findings in contemporary dental practice in association with dental pathology or dental care. They have also been studied from an anthropological background. The purpose of this study was to compare the prevalence of apical and dental lesions in an archeological Middle Ages sampl...
journal_title：Clinical oral investigations
pub_type： 历史文章,杂志文章
doi：10.1007/s00784-005-0318-3
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to assess postoperative pain in a prospective randomized clinical trial comparing two groups, using the Reciproc® system in one group and the ProTaper® rotary system in the other. MATERIAL AND METHODS:The study included 78 male patients, aged 18-64 years (mean age of 26 years), wit...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-015-1692-0
更新日期：2016-11-01 00:00:00
abstract：:This study evaluated by standardised digitised periapical radiography the crestal bone maintenance around modified diameter internal hex implants with variable thread design and narrow neck loaded with different procedures. Forty implants were placed in 25 patients. Twenty implants were conventionally loaded, 20 ones ...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-009-0314-0
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to determine the frequency and quality of root canal fillings (RCF) and the prevalence of apical radiolucency (AR) in a German population. MATERIAL AND METHODS:Five hundred randomly selected full-size CBCT images (Planmeca ProMax 3D, FOV = 8 × 8 cm, voxel size 160 μm or 200 μm) wer...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-019-02985-y
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the systemic and periodontal conditions, as well as the determinants of health in pregnant women with and without obesity/overweight during the second and third trimesters of pregnancy and after delivery. MATERIALS AND METHODS:In the second trimester (T1), 93 pregnant women were divided into two ...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-019-02932-x
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVES:The aim of the present study was the qualitative and quantitative evaluation of osseous graft consolidation using allogeneic bone blocks for vertical bone augmentation in an animal model. MATERIAL AND METHODS:Standardised allogeneic and autologous bone blocks were fixed on the frontal skull of 20 adult fema...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-019-03151-0
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVES:In this in vitro study, we assessed filling characteristics (adaptation, homogeneity, sealer percentage, position of the carrier) of warm and cold obturation methods in curved root canals. MATERIALS AND METHODS:A reciprocating method was used to prepare 90 curved roots (25 ° average curvature) to an apical ...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1674-2
更新日期：2016-09-01 00:00:00
abstract：:From a preventive point of view collection of data concerning carious and non-carious cervical tooth defects is definitely important. Consequently, the prevalence and distribution of different root lesions were studied and correlated with behavioral and biological factors in 50- to 60-year-old German individuals (n = ...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s007840050097
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVE:Aggregatibacter actinomycetemcomitans, specially its highly leucotoxic strain (JP2 clone), represents an etiological factor for the onset and progression of aggressive types of periodontitis. The aims of this investigation were to investigate the most relevant periodontal pathogens in the subgingival microbio...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1653-7
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to compare the effects of periodontal treatment on the inflammatory markers in gingival crevicular fluid and the concentration of salivary cortisol between non-pregnant and pregnant women with gingivitis. MATERIALS AND METHODS:This study included 30 non-pregnant women (mean age 27....
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2569-9
更新日期：2018-07-31 00:00:00
abstract：:The aim of this randomized double-blinded preliminary study was to evaluate the clinical and microbiological long-term effects of an essential-oil-containing mouth rinse as the active agent utilized in the "one-stage full-mouth disinfection protocol." Probing pocket depth and plaque and gingival indices were evaluated...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-008-0219-3
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVES:To assess the perception of oral health and oral care needs, barriers and current practices as perceived by managers and caregivers in organizations for people with disabilities in Flanders. MATERIALS AND METHODS:Two questionnaires were developed, one for managers and one for caregivers. The questionnaires ...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-019-03071-z
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to evaluate and compare the osteoblastic differentiation ability of dedifferentiated fat (DFAT) cells and adipose stem cells (ASCs) from the buccal fat pad (BFP). MATERIALS AND METHODS:We isolated human DFAT cells and ASCs from the BFP of a patient who underwent oral and maxill...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-013-1166-1
更新日期：2014-11-01 00:00:00
abstract：:This study compared shear bond strengths of six self-adhesive resin cements to zirconium oxide ceramic with and without air-particle abrasion. One hundred twenty zirconia samples were air-abraded (group SB; n = 60) or left untreated (group NO). Composite cylinders were bonded to the zirconia samples with either BisCem...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-009-0278-0
更新日期：2010-04-01 00:00:00
abstract：:The aim of the current study was to evaluate the prevalence of psychopathological symptoms in patients who self-reported different forms of bruxism by means of clinical and anamnestic diagnostic criteria. Eighty-five participants were divided into four groups as sleep bruxers (12), awake bruxers (24), sleep-awake brux...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-010-0492-9
更新日期：2012-02-01 00:00:00
abstract：:Squamous cell carcinoma (SCC) of the oral cavity is an extremely invasive tumour of stratified squamous epithelium that spreads throughout degradation of the basement membrane (BM) and extra-cellular matrix. Oral verrucous carcinoma (VC) is a rare low-grade variant of oral SCC that penetrates into the subepithelial co...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-009-0296-y
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVES:The purpose of this case series was to evaluate the new bone formation following guided bone regeneration (GBR) with a calcium phosphosilicate (CPS), alloplastic bone putty at peri-implant dehiscence defects and to assess survival rate of implants placed in the augmented sites after 12 months of function. M...
journal_title：Clinical oral investigations
pub_type： 杂志文章,多中心研究
doi：10.1007/s00784-014-1268-4
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:This work aimed to study the role of inflammation in medication-related osteonecrosis of the jaw (MRONJ) in rats with focus on Wnt signaling. METHODS:A total of 36 female Wistar rats (12 weeks ± 200 g) were divided into 2 groups (n = 6) in 3 experiments: saline (SAL) and zoledronic acid (ZOL). For MRONJ indu...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03551-7
更新日期：2021-02-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to investigate whether the osteoinductive properties of bone-conditioned medium (BCM) harvested from cortical bone chips within a clinically relevant short-term period can enhance the biologic characteristics of deproteinized bovine bone mineral (DBBM) in vitro. MATERIALS AND METHOD...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03528-6
更新日期：2020-09-01 00:00:00
abstract：AIM:The aim of this study was to compare the effectiveness of 2% articaine and 2% lignocaine in achieving adequate anesthesia in children between the age group of 6-13 years using inferior alveolar nerve block. METHODS:A triple blinded randomized controlled trial was conducted in 180 participants (90 patients- 2% arti...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-018-2775-5
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVES:Targeted modifications of the bulk implant surfaces using bioactive agents provide a promising tool for improvement of the long-term bony and soft tissue integration of dental implants. In this study, we assessed the cellular responses of primary human gingival fibroblasts (HGF) to different surface modifica...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-016-1784-5
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVES:Previous research revealed that autogenous tooth roots may be biologically equivalent to conventional bone grafts for lateral ridge augmentation. However, these analyses were limited to two dimensions, whereas healing is a volumetric process. The present study aimed at volumetrically assessing the microstruc...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2723-4
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:The aim of this prospective, randomized, clinical study was to assess the effect of photobiomodulation therapy (PBM) with low-level laser irradiation (LLLI) on postoperative pain after endodontic treatment. MATERIALS AND METHODS:Sixty patients, diagnosed with irreversible pulpitis in lower molar teeth, parti...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-018-2435-9
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVES:To date, scarce evidence exists around the application of subgingival air polishing during treatment of severe periodontitis. The aim of this study was to evaluate the benefits of subgingival air polishing during non-surgical treatment of deep bleeding pockets in stages III-IV periodontitis patients MATERIAL...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-020-03648-z
更新日期：2021-02-01 00:00:00
abstract：OBJECTIVE:The objective of this in vitro study was to investigate fracture load, fracture types, and impact of chewing simulation of human molars restored with 3D printed indirect polyetheretherketone (PEEK) inlays and compare these with milled indirect PEEK inlays, direct resin composite fillings, and sound teeth. MA...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03216-5
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVES:Geranylgeraniol (GGOH) has been reported as a potential treatment option for bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ). The aim of this study was to analyze the effects of GGOH on endothelial progenitor cells (EPC) after bisphosphonate treatment in vitro. MATERIALS AND METHODS:EPC were in...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-014-1394-z
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVES:Analgesics are one of the most frequently used medicines. Self-medication and misuse have been described in the literature. The purpose of this study was to document analgesic (mis)use in a population seeking emergency dental treatment. MATERIAL AND METHODS:Patients consulting a dental emergency service wer...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-017-2228-6
更新日期：2018-04-01 00:00:00
abstract：OBJECTIVES:The present study aims to investigate the relevance of immunohistochemical p53 expression in carcinomas of the oral cavity and of the head and neck region. Long-term clinical and histopathological follow-up findings as well as HPV status are correlated with the results of this examination. MATERIALS AND MET...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-013-0939-x
更新日期：2014-01-01 00:00:00
