Effectiveness of 2% Articaine as an anesthetic agent in children: randomized controlled trial.

Abstract:

AIM:The aim of this study was to compare the effectiveness of 2% articaine and 2% lignocaine in achieving adequate anesthesia in children between the age group of 6-13 years using inferior alveolar nerve block. METHODS:A triple blinded randomized controlled trial was conducted in 180 participants (90 patients- 2% articaine, 90 patients-2% lignocaine). Effectiveness of the anesthetic agent was determined at 3 points determined by subjective evaluation of pain using pain scales (FPS-R). Paired sample t-test and chi square test were performed for statistical significance. RESULT:Anesthetic success for 2% articaine were 64.4%, 42.2% and 81.8% respectively. The anesthetic success of 2% lignocaine was 66.7%, 48.9% and 85.7% at point one, point two and point three respectively (p > 0.05). CONCLUSION:This study concludes that 2% articaine in 1:2,00,000 did not demonstrate superior clinical effectiveness in comparison to 2% lignocaine. CLINICAL SIGNIFICANCE:Lignocaine has always been considered the gold standard. With its unique chemical structure and increased potency, Articaine has been gaining popularity. Its efficacy in 2% concentration had not been compared to 2% lignocaine. 2% articaine did not show clinical superiority but its comparable effectiveness with lignocaine can encourage further research in using articaine in reduced concentrations to improve effectiveness.

journal_name

Clin Oral Investig

authors

Ramadurai N,Gurunathan D,Samuel AV,Subramanian E,Rodrigues SJL

doi

10.1007/s00784-018-2775-5

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

3543-3550

issue

9

eissn

1432-6981

issn

1436-3771

pii

10.1007/s00784-018-2775-5

journal_volume

23

pub_type

杂志文章,随机对照试验
  • Why, when, and how general practitioners restore endodontically treated teeth: a representative survey in Germany.

    abstract:OBJECTIVE:The purpose of this study was to assess current opinions, applied techniques, and materials for the restoration of endodontically treated teeth (ETT) in a nationwide survey in Germany. MATERIAL AND METHODS:Completed questionnaires from 1,648 dentists were returned (response rate 63%). RESULTS:In general, po...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-015-1505-5

    authors: Naumann M,Neuhaus KW,Kölpin M,Seemann R

    更新日期:2016-03-01 00:00:00

  • Aberrant expression of β-catenin and its association with ΔNp63, Notch-1, and clinicopathological factors in oral squamous cell carcinoma.

    abstract::The present study focuses on the correlation between the expression pattern of β-catenin (component of Wnt signaling), ΔNp63 (proliferation marker), and Notch 1 (transmembrane receptor) in oral squamous cell carcinoma. The study also aims to investigate the interaction between β-catenin and ΔNp63 in oral cancer. Furth...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-011-0605-0

    authors: Ravindran G,Devaraj H

    更新日期:2012-08-01 00:00:00

  • Investigation of the prevalence, clinical features, and risk factors of dentin hypersensitivity in a selected Brazilian population.

    abstract:OBJECTIVES:To evaluate the prevalence, clinical features, and risk factors of dentin hypersensitivity (DH) in a Brazilian population. MATERIALS AND METHODS:300 patients at the Dentistry Clinic of the University of São Paulo participated in this study. The subjects completed a questionnaire regarding their personal inf...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-013-1008-1

    authors: Scaramucci T,de Almeida Anfe TE,da Silva Ferreira S,Frias AC,Sobral MA

    更新日期:2014-01-01 00:00:00

  • Efficacy of cleansing agents in killing microorganisms in mixed species biofilms present on silicone facial prostheses--an in vitro study.

    abstract:OBJECTIVES:The purpose of this study was to assess the efficacy of different cleansing agents in killing mixed species biofilms on silicone facial prostheses. MATERIALS AND METHODS:Two bacterial and three yeast strains, isolated from silicone facial prostheses, were selected for the mixed species biofilms. A variety o...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-015-1453-0

    authors: Ariani N,Visser A,Teulings MR,Dijk M,Rahardjo TB,Vissink A,van der Mei HC

    更新日期:2015-12-01 00:00:00

  • Osteogenic gene array of osteoblasts cultured on a novel osteoinductive biphasic calcium phosphate bone grafting material.

    abstract:OBJECTIVES:Recently, novel biphasic calcium phosphate (BCP) scaffolds have emerged as a new class of bone grafts with osteoinductive potential demonstrating the ability to form ectopic bone in extra-skeletal sites. The aim of the present study was to perform an osteogenic gene array to target possible genes responsible...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-016-1825-0

    authors: Miron RJ,Shuang Y,Bosshardt DD,Caballé-Serrano J,Chandad F,Zhang Y

    更新日期:2017-04-01 00:00:00

  • Fluoride toothpaste supplemented with sodium hexametaphosphate reduces enamel demineralization in vitro.

    abstract:OBJECTIVE:The aim of this study was to evaluate the effect of fluoride dentifrices combined with sodium hexametaphosphate (HMP) on enamel demineralization in vitro. MATERIAL AND METHODS:Enamel bovine blocks were selected by initial surface hardness (SHi) and then divided into five experimental groups (n = 12): placebo...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-015-1707-x

    authors: da Camara DM,Pessan JP,Francati TM,Souza JA,Danelon M,Delbem AC

    更新日期:2016-11-01 00:00:00

  • Reply to: letter to the editor about the article published in Clinical Oral Investigations tilted: impacted and transmigrated mandibular canines: an analysis of 3D radiographic imaging data (Bertl MH, Frey C, Bertl K, Giannis K, Gahleitner A, Strbac GD (2

    abstract:: ...

    journal_title:Clinical oral investigations

    pub_type: 评论,信件

    doi:10.1007/s00784-018-2636-2

    authors: Bertl MH,Frey C,Bertl K,Giannis K,Gahleitner A,Strbac GD

    更新日期:2018-11-01 00:00:00

  • Effect of an intensified treatment with 40% chlorhexidine varnish on plaque acidogenicity.

    abstract::Previous work showed that a single application of 40% chlorhexidine varnish, EC40, reduced plaque acidogenicity upon sucrose challenge during less than 3 weeks. It was questioned whether lactic acid production could be reduced significantly longer when the treatment was intensified. Therefore, the effects of three con...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-006-0079-7

    authors: Gerardu VA,Buijs MJ,ten Cate JM,van Loveren C

    更新日期:2007-03-01 00:00:00

  • Removal of stones from the superficial lobe of the submandibular gland (SMG) via an intraoral endoscopy-assisted sialolithotomy.

    abstract:OBJECTIVES:Sialolithiasis is the most common cause of chronic sialadenitis of the submandibular gland (SMG). Symptomatic superficial lobe stones are often treated by submandibulectomy. A gland preserving operation allows for transoral stone removal through endoscopically assisted sialolithotomy. Herein, we provide clin...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-019-02853-9

    authors: Sproll C,Naujoks C,Holtmann H,Kübler NR,Singh DD,Rana M,Lommen J

    更新日期:2019-11-01 00:00:00

  • Experimental peri-implantitis around titanium implants with a chemically modified surface with a monolayer of multi-phosphonate molecules: a preclinical in vivo investigation.

    abstract:OBJECTIVES:The purpose of this experimental in vivo investigation was to evaluate the influence of modifying the implant surface by adding a monolayer of multi-phosphonate molecules on the development of experimental peri-implantitis. MATERIAL AND METHODS:Eight beagle dogs received 5 tests and 5 control implants each ...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-020-03708-4

    authors: Sanz-Esporrin J,Di Raimondo R,Pla R,Luengo F,Vignoletti F,Núñez J,Antonoglou GJ,Blanco J,Sanz M

    更新日期:2021-01-06 00:00:00

  • P53 immunohistochemical expression does not correlate with clinical features in 207 carcinomas of the oral cavity and in the head and neck region.

    abstract:OBJECTIVES:The present study aims to investigate the relevance of immunohistochemical p53 expression in carcinomas of the oral cavity and of the head and neck region. Long-term clinical and histopathological follow-up findings as well as HPV status are correlated with the results of this examination. MATERIALS AND MET...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-013-0939-x

    authors: Gröbe A,Hanken H,Al-Dam A,Cachovan G,Smeets R,Krohn A,Clauditz T,Grob T,Simon R,Sauter G,Kluwe L,Heiland M,Blessmann M

    更新日期:2014-01-01 00:00:00

  • Do edible oils reduce bacterial colonization of enamel in situ?

    abstract:OBJECTIVE:Edible oils are an empiric approach for the prevention of oral diseases. The present in situ study investigated the effect of edible oils on initial bacterial colonization of enamel surfaces. METHODS AND MATERIALS:Initial biofilm formation was performed on enamel specimens mounted on maxillary splints and ca...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00784-012-0734-0

    authors: Hannig C,Kirsch J,Al-Ahmad A,Kensche A,Hannig M,Kümmerer K

    更新日期:2013-03-01 00:00:00

  • Non-surgical periodontal treatment improves rheumatoid arthritis disease activity: a meta-analysis.

    abstract:OBJECTIVES:The aim of the meta-analysis was to clarify the efficacy of non-surgical periodontal treatment (NSPT) in improving rheumatoid arthritis (RA) disease activity. METHODS:A systematic literature search was conducted using the PubMed, Embase, and Cochrane databases up to October 2020. A total of nine studies wer...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-021-03807-w

    authors: Sun J,Zheng Y,Bian X,Ge H,Wang J,Zhang Z

    更新日期:2021-01-29 00:00:00

  • Comparison of the efficacy of a novel sustained release clotrimazole varnish and clotrimazole troches for the treatment of oral candidiasis.

    abstract:OBJECTIVES:Candida albicans is a common fungal infection and is commensal in 40-65 % of healthy adults. The development and pharmacokinetics of a novel sustained release clotrimazole varnish (Clot-SRV) for topical oral use have been reported. The aim of this study was to compare the efficacy of this varnish with clotri...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-014-1259-5

    authors: Czerninski R,Pikovsky A,Gati I,Friedman M,Steinberg D

    更新日期:2015-03-01 00:00:00

  • Platform switching vs standard implants in partially edentulous patients using the Dental Tech Implant System: clinical and radiological results from a prospective multicenter study.

    abstract:OBJECTIVES:The main objective of this study was to evaluate clinical and radiographic outcomes of implant-supported fixed partial prostheses, comparing platform switching and standard platform concepts. MATERIALS AND METHODS:Patients with single or multiple partial edentulism were included in this prospective multicen...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00784-015-1462-z

    authors: Del Fabbro M,Bianchessi C,Del Lupo R,Landi L,Taschieri S,Corbella S

    更新日期:2015-12-01 00:00:00

  • Competing interplay between systemic and periodontal inflammation: obesity overrides the impact of oral periphery.

    abstract:OBJECTIVES:We aimed at investigating whether the interaction between the local inflammation, periodontitis, and obesity is independently associated with systemic inflammation. METHODS:From the population-based Study of Health in Pomerania, 3366 participants, without (2366) and with (1000) obesity, were studied for the...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-020-03514-y

    authors: Meisel P,Pink C,Pitchika V,Nauck M,Völzke H,Kocher T

    更新日期:2020-08-22 00:00:00

  • Microstructural volumetric analysis of lateral ridge augmentation using differently conditioned tooth roots.

    abstract:OBJECTIVES:Previous research revealed that autogenous tooth roots may be biologically equivalent to conventional bone grafts for lateral ridge augmentation. However, these analyses were limited to two dimensions, whereas healing is a volumetric process. The present study aimed at volumetrically assessing the microstruc...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-018-2723-4

    authors: Becker K,Jandik K,Stauber M,Mihatovic I,Drescher D,Schwarz F

    更新日期:2019-07-01 00:00:00

  • Halogen and LED light curing of composite: temperature increase and Knoop hardness.

    abstract::This study assessed the Knoop hardness and temperature increase provided by three light curing units when using (1) the manufacturers' recommended times of photo-activation and (2) standardizing total energy density. One halogen--XL2500 (3M/ESPE)--and two light-emitting diode (LED) curing units--Freelight (3M/ESPE) an...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-005-0028-x

    authors: Schneider LF,Consani S,Correr-Sobrinho L,Correr AB,Sinhoreti MA

    更新日期:2006-03-01 00:00:00

  • Analysis of blood supply in the hard palate and maxillary tuberosity-clinical implications for flap design and soft tissue graft harvesting (a human cadaver study).

    abstract:OBJECTIVES:The aim of the present study is to provide a detailed macroscopic mapping of the palatal and tuberal blood supply applying anatomical methods and studying specific anastomoses to bridge the gap between basic structural and empirical clinical knowledge. MATERIALS AND METHODS:Ten cadavers (three dentate, seve...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-018-2538-3

    authors: Shahbazi A,Grimm A,Feigl G,Gerber G,Székely AD,Molnár B,Windisch P

    更新日期:2019-03-01 00:00:00

  • A clinical comparison of autogenous bone graft with and without autogenous periodontal ligament graft in the treatment of periodontal intrabony defects.

    abstract::The aim of the present study was to evaluate the efficacy of autogenous bone graft (ABG) with and without autogenous periodontal ligament graft (PDLG) in the management of human two-wall intrabony periodontal defects. Twenty-six similar two-wall intrabony periodontal defects with >or=5 mm probing depths and >or=3 mm d...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00784-008-0235-3

    authors: Shirmohammadi A,Chitsazi MT,Lafzi A

    更新日期:2009-09-01 00:00:00

  • Cell sheets of human dental pulp stem cells for future application in bone replacement.

    abstract:OBJECTIVES:To analyze the potential of human dental pulp stem cells (hDPSCs) for maintaining their undifferentiated status and osteogenic differentiation capacity when arranged in cell sheets (CSs) for future application in bone replacement. MATERIALS AND METHODS:CSs were formed after being induced for 10-15 days by c...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-018-2630-8

    authors: Pedroni ACF,Sarra G,de Oliveira NK,Moreira MS,Deboni MCZ,Marques MM

    更新日期:2019-06-01 00:00:00

  • Clinical performance of a light-cured denture base material compared to polymethylmethacrylate--a randomized clinical study.

    abstract::The aim of this study was to evaluate the clinical long-term performance of a visible light-cured resin (VLCR) denture base material and to compare it to a well-established polymethylmethacrylate (PMMA)-based denture acrylic in a randomized split-mouth clinical long-term study. One hundred removable partial dentures i...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00784-011-0572-5

    authors: Gohlke-Wehrße HL,Giese-Kraft K,Wöstmann B

    更新日期:2012-06-01 00:00:00

  • Analgesia (mis)usage on a dental emergency service: a patient survey.

    abstract:OBJECTIVES:Analgesics are one of the most frequently used medicines. Self-medication and misuse have been described in the literature. The purpose of this study was to document analgesic (mis)use in a population seeking emergency dental treatment. MATERIAL AND METHODS:Patients consulting a dental emergency service wer...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-017-2228-6

    authors: Hommez G,Ongena B,Cauwels RGEC,De Paepe P,Christiaens V,Jacquet W

    更新日期:2018-04-01 00:00:00

  • Could digital imaging be an alternative for digital colorimeters?

    abstract::This study evaluated the colour parameters of composite and ceramic shade guides determined using a colorimeter and digital imaging method with illuminants at different colour temperatures. Two different resin composite shade guides, namely Charisma (Heraeus Kulzer) and Premise (Kerr Corporation), and two different ce...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-009-0329-6

    authors: Caglar A,Yamanel K,Gulsahi K,Bagis B,Ozcan M

    更新日期:2010-12-01 00:00:00

  • Dyes for caries detection: influence on composite and compomer microleakage.

    abstract::The aim of this study was to evaluate the influence of caries-detecting dyes on the microleakage of adhesive materials. Sixty cubic class V cavities were prepared on buccal and lingual surfaces of 30 human third molars. Coronal margins were located in enamel and gingival margins in cementum. The teeth were randomly di...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-002-0182-3

    authors: Piva E,Meinhardt L,Demarco FF,Powers JM

    更新日期:2002-12-01 00:00:00

  • Enamel wear by antagonistic restorative materials under erosive conditions.

    abstract:OBJECTIVES:This study aimed to analyse loss of enamel worn against composite, leucite glass ceramic or enamel antagonists under non-erosive and alternating or simultanuous erosive-attritive conditions. MATERIALS AND METHODS:Flat human enamel specimens were loaded (1 Hz, 300 g loading weight, each subgroup n = 12) with...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-017-2071-9

    authors: Wiegand A,Credé A,Tschammler C,Attin T,Tauböck TT

    更新日期:2017-12-01 00:00:00

  • Regulation of p53 under hypoxic and inflammatory conditions in periodontium.

    abstract:OBJECTIVES:Different studies suggest that inflammation as well as hypoxia leads to an increase of p53 protein levels. However, the implication of p53 during oral inflammatory processes is still unknown. The aim of this study was therefore to investigate the effect of hypoxia and inflammation on p53 regulation in human ...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-015-1679-x

    authors: Memmert S,Gölz L,Pütz P,Jäger A,Deschner J,Appel T,Baumgarten G,Rath-Deschner B,Frede S,Götz W

    更新日期:2016-09-01 00:00:00

  • Effect of dentinal pretreatments on coronal dentin primary carious lesions: a field emission SEM study.

    abstract::The aim of the study was the morphological analysis of coronal dentin caries and the modifications induced by different pretreatments with phosphoric acid or sodium hypochlorite. Carious dentin specimens were obtained from human molars affected by carious lesions. Specimens were divided in four groups and submitted to...

    journal_title:Clinical oral investigations

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s00784-003-0221-8

    authors: Breschi L,Gobbi P,Falconi M,Ruggeri A Jr,Mazzotti G,Di Lenarda R,Prati C

    更新日期:2003-09-01 00:00:00

  • Apical filling characteristics of carrier-based techniques vs. single cone technique in curved root canals.

    abstract:OBJECTIVES:In this in vitro study, we assessed filling characteristics (adaptation, homogeneity, sealer percentage, position of the carrier) of warm and cold obturation methods in curved root canals. MATERIALS AND METHODS:A reciprocating method was used to prepare 90 curved roots (25 ° average curvature) to an apical ...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-015-1674-2

    authors: Neuhaus KW,Schick A,Lussi A

    更新日期:2016-09-01 00:00:00

  • Root lesions in a group of 50-60 year-old Germans related to clinical and social factors.

    abstract::From a preventive point of view collection of data concerning carious and non-carious cervical tooth defects is definitely important. Consequently, the prevalence and distribution of different root lesions were studied and correlated with behavioral and biological factors in 50- to 60-year-old German individuals (n = ...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s007840050097

    authors: Hahn P,Reinhardt D,Schaller HG,Hellwig E

    更新日期:1999-12-01 00:00:00