Osseous ingrowth in allogeneic bone blocks applied for vertical bone augmentation: a preclinical randomised controlled study.

Abstract:

OBJECTIVES:The aim of the present study was the qualitative and quantitative evaluation of osseous graft consolidation using allogeneic bone blocks for vertical bone augmentation in an animal model. MATERIAL AND METHODS:Standardised allogeneic and autologous bone blocks were fixed on the frontal skull of 20 adult female pigs and covered with a resorbable collagen membrane. Animals were sacrificed after 2 and 6 months. Specimens were histologically and histomorphometrically analysed focusing on the amount of vital bone, residual bone substitute material and connective tissue. Furthermore, the amount of expression of bone matrix proteins (collagen type I and osteocalcin) and de novo vessel formation (von Willebrand factor) were quantified by immunohistochemistry. RESULTS:Significantly more allogeneic bone blocks failed for both evaluation time points (p < 0.05). Allogeneic blocks showed significantly less vital bone with more connective tissue formation compared to autologous bone blocks. Increased vessel formation could be detected for both evaluation time points in the contact area of autologous bone with local bone. The expression of collagen type I and osteocalcin was significantly lower in the allogeneic bone graft. CONCLUSIONS:Allogeneic cancellous bone blocks showed a significantly higher failure rate compared to autologous bone blocks. Allogeneic bone blocks seemed to negatively affect bone formation or negatively influence the host in the long term, and increased connective tissue formation and block loss should be anticipated. CLINICAL RELEVANCE:In order to maintain patient safety and treatment success clinicians should be persuaded to make a conscious choice of the applied biomaterials with regard to their components and structure.

journal_name

Clin Oral Investig

authors

Moest T,Frabschka J,Kesting MR,Schmitt CM,Frohwitter G,Lutz R,Schlegel KA

doi

10.1007/s00784-019-03151-0

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

2867-2879

issue

8

eissn

1432-6981

issn

1436-3771

pii

10.1007/s00784-019-03151-0

journal_volume

24

pub_type

杂志文章
  • Histotomography of the odontoblast processes at the dentine-enamel junction of permanent healthy human teeth in the confocal laser scanning microscope.

    abstract::The translucency of teeth allows the non-destructive subsurface visualisation of their microstructure by confocal laser scanning microscopy (CLSM) at a level of about 150 microns below the surface. The dentine-enamel junction (DEJ) is accessible only directly adjacent to the cervix of the tooth. Therefore teeth have t...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s007840050038

    authors: Grötz KA,Duschner H,Reichert TE,de Aguiar EG,Götz H,Wagner W

    更新日期:1998-03-01 00:00:00

  • Resin composites: strength of the bond to dentin versus mechanical properties.

    abstract::This study (1) investigated whether the combination of an adhesive system from one manufacturer with a resin composite from the same manufacturer provides superior bonding of the resin composite to dentin compared with the combination of an adhesive system from one manufacturer with a resin composite from another manu...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-006-0077-9

    authors: Thomsen KB,Peutzfeldt A

    更新日期:2007-03-01 00:00:00

  • P53 immunohistochemical expression does not correlate with clinical features in 207 carcinomas of the oral cavity and in the head and neck region.

    abstract:OBJECTIVES:The present study aims to investigate the relevance of immunohistochemical p53 expression in carcinomas of the oral cavity and of the head and neck region. Long-term clinical and histopathological follow-up findings as well as HPV status are correlated with the results of this examination. MATERIALS AND MET...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-013-0939-x

    authors: Gröbe A,Hanken H,Al-Dam A,Cachovan G,Smeets R,Krohn A,Clauditz T,Grob T,Simon R,Sauter G,Kluwe L,Heiland M,Blessmann M

    更新日期:2014-01-01 00:00:00

  • A retrospective cephalometric investigation of two fixed functional orthodontic appliances in class II treatment: Functional Mandibular Advancer vs. Herbst appliance.

    abstract:OBJECTIVE:The objective of the study is to compare skeletal and dental changes in class II patients treated with fixed functional appliances (FFA) that pursue different biomechanical concepts: (1) FMA (Functional Mandibular Advancer) from first maxillary molar to first mandibular molar through inclined planes and (2) H...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-017-2111-5

    authors: Kinzinger GSM,Lisson JA,Frye L,Gross U,Hourfar J

    更新日期:2018-01-01 00:00:00

  • Treatment outcome of bimaxillary surgery for asymmetric skeletal class II deformity.

    abstract:OBJECTIVES:Facial asymmetry is one of the main concerns in patients with a dentofacial deformity. The aims of the study were to (1) evaluate the changes in facial asymmetry after bimaxillary surgery for asymmetric skeletal class II deformity and (2) compare preoperative and postoperative facial asymmetry of class II pa...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-018-2462-6

    authors: Chen YF,Liao YF,Chen YA,Chen YR

    更新日期:2019-02-01 00:00:00

  • Clinical performance of a nanofilled resin composite with and without an intermediary layer of flowable composite: a 2-year evaluation.

    abstract::The objective of this prospective clinical follow-up was to evaluate the 2-year clinical performance of a nanofilled resin composite in class II restorations. The restorations were made with and without intermediary layer of a nanofilled flowable resin composite studied in an intraindividual comparison. Each participa...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00784-010-0485-8

    authors: Stefanski S,van Dijken JW

    更新日期:2012-02-01 00:00:00

  • Digital subtraction radiography in detection of vertical root fractures: accuracy evaluation for root canal filling, fracture orientation and width variables. An ex-vivo study.

    abstract:OBJECTIVE:Ex-vivo evaluation of the detectability of vertical root fractures (VRFs) using digital subtraction radiography (DSR) and conventional digital periapical radiography (CDPR); investigation of the effect of root canal filling, x-ray angulation, and thickness of the VRF in the diagnostic accuracy. MATERIALS AND...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-020-03245-0

    authors: Kapralos V,Koutroulis A,Irinakis E,Kouros P,Lyroudia K,Pitas I,Mikrogeorgis G

    更新日期:2020-10-01 00:00:00

  • Diagnostic accuracy of ultrasound, ¹⁸F-FDG-PET/CT, and fused ¹⁸F-FDG-PET-MR images with DWI for the detection of cervical lymph node metastases of HNSCC.

    abstract:OBJECTIVE:This study aimed to compare (18)F-fluorodesoxyglucose positron emission tomography/MRI ((18)F-FDG-PET-MRI) fusion images, including diffusion-weighted imaging (DWI), (18)F-FDG-PET/CT, and ultrasound (US) regarding their performance in nodal staging of patients with head and neck squamous cell carcinoma (HNSCC...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-013-1050-z

    authors: Heusch P,Sproll C,Buchbender C,Rieser E,Terjung J,Antke C,Boeck I,Macht S,Scherer A,Antoch G,Heusner TA,Handschel J

    更新日期:2014-04-01 00:00:00

  • Reconstruction of the alveolar cleft: can growth factor-aided tissue engineering replace autologous bone grafting? A literature review and systematic review of results obtained with bone morphogenetic protein-2.

    abstract::The alveolar cleft in patients with clefts of lip, alveolus and palate (CLAP) is usually reconstructed with an autologous bone graft. Harvesting of autologous bone grafts is associated with more or less donor site morbidity. Donor site morbidity could be eliminated if bone is fabricated by growth factor-aided tissue e...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,评审

    doi:10.1007/s00784-011-0547-6

    authors: van Hout WM,Mink van der Molen AB,Breugem CC,Koole R,Van Cann EM

    更新日期:2011-06-01 00:00:00

  • Expression of growth mediators in the gingival crevicular fluid of patients with aggressive periodontitis undergoing periodontal surgery.

    abstract:OBJECTIVES:To describe changes in growth factor mediators in the gingival crevicular fluid (GCF) of patients with aggressive periodontitis (AgP) undergoing regenerative (GTR) and access flap (AF) surgery. MATERIALS AND METHODS:This was a 12-month, single-blind, split-mouth RCT involving 18 AgP patients with a bilatera...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-018-2752-z

    authors: Rakmanee T,Calciolari E,Olsen I,Darbar U,Griffiths GS,Petrie A,Donos N

    更新日期:2019-08-01 00:00:00

  • Position of lower wisdom teeth and their relation to the alveolar nerve in orthodontic patients treated with and without extraction of premolars: a longitudinal study.

    abstract:OBJECTIVES:The present longitudinal study aimed to compare changes in the lower third molar position and nerve involvement in orthodontically treated patients with and without premolar extractions. MATERIALS AND METHODS:The sample consisted of pretreatment and posttreatment panoramic radiographs of 349 orthodontically...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-013-1148-3

    authors: Miclotte A,Van Hevele J,Roels A,Elaut J,Willems G,Politis C,Jacobs R

    更新日期:2014-09-01 00:00:00

  • Imaging of nano-hydroxyapatite/chitosan scaffolds using a cone beam computed tomography device on rat calvarial defects with histological verification.

    abstract:OBJECTIVES:Τhis study aims at determining the ability of cone beam computed tomography (CBCT) to visualize critical-size defects (CSD) created at rat calvaria and filled with 75/25 w/w nano-hydroxyapatite/chitosan (nHAp/CS) scaffolds, prior to their histological investigation. MATERIALS AND METHODS:Thirty adult Spragu...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-019-02939-4

    authors: Chatzipetros E,Yfanti Z,Christopoulos P,Donta C,Damaskos S,Tsiambas E,Tsiourvas D,Kalogirou EM,Tosios KI,Tsiklakis K

    更新日期:2020-01-01 00:00:00

  • Pragmatic approach to manage new oral anticoagulants in patients undergoing dental extractions: a prospective case-control study.

    abstract:OBJECTIVES:The aim of this study was to validate a standardized pragmatic approach to manage new oral anticoagulants (NOACs) in patients who undergo dental extractions. MATERIALS AND METHODS:This prospective case-control study in patients undergoing dental extraction included 26 patients (mean age 76 years, 57% male) ...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-016-2010-1

    authors: Miclotte I,Vanhaverbeke M,Agbaje JO,Legrand P,Vanassche T,Verhamme P,Politis C

    更新日期:2017-09-01 00:00:00

  • Dental bleaching on teeth submitted to enamel microabrasion 30 years ago-a case report of patients' compliance during bleaching treatment.

    abstract:OBJECTIVES:The present dental bleaching case report describes a new method that precisely quantifies the daily wearing-times of the bleaching product by inserting a microsensor in the acetate custom tray. The bleaching efficacy was also discussed since the patient was previously submitted to enamel microabrasion. METH...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-018-2439-5

    authors: Sundfeld D,Pavani CC,Schott TC,Machado LS,Pini NIP,Bertoz APM,Sundfeld RH

    更新日期:2019-01-01 00:00:00

  • Autotransplantation of teeth in humans: a systematic review and meta-analysis.

    abstract:OBJECTIVES:The aim of this investigation was to assess the currently available evidence concerning the complications and risk factors influencing the outcome of autotransplantation of teeth in humans. MATERIALS AND METHODS:Electronic searches were conducted to identify randomized controlled and prospective clinical tr...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00784-015-1473-9

    authors: Almpani K,Papageorgiou SN,Papadopoulos MA

    更新日期:2015-07-01 00:00:00

  • Light transmittance and micro-mechanical properties of bulk fill vs. conventional resin based composites.

    abstract:OBJECTIVES:The aim of this study was to quantify the blue light that passes through different incremental thicknesses of bulk fill in comparison to conventional resin-based composites (RBCs) and to relate it to the induced mechanical properties. MATERIALS AND METHODS:Seven bulk fill, five nanohybrid and two flowable R...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-013-1177-y

    authors: Bucuta S,Ilie N

    更新日期:2014-11-01 00:00:00

  • Efficacy of fluoride varnish for preventing white spot lesions and gingivitis during orthodontic treatment with fixed appliances-a prospective randomized controlled trial.

    abstract:OBJECTIVES:The development of white spot lesions around orthodontic brackets and gingivitis is a common problem during orthodontic treatment with fixed appliances. This prospective randomized double-blind controlled clinical trial investigated the preventive efficacy of a one-time application of two commonly used fluor...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00784-016-1730-6

    authors: Kirschneck C,Christl JJ,Reicheneder C,Proff P

    更新日期:2016-12-01 00:00:00

  • Association between recurrent aphthous stomatitis and Helicobacter pylori infection: a meta-analysis.

    abstract:OBJECTIVES:Several studies have shown the possible involvement of Helicobacter pylori infection in individuals with recurrent aphthous stomatitis (RAS), but the relationship remains controversial. This meta-analysis was performed to validate the association between RAS and H. pylori infection. MATERIALS AND METHODS:Th...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00784-014-1230-5

    authors: Li L,Gu H,Zhang G

    更新日期:2014-07-01 00:00:00

  • Neoplasms and non-neoplastic pathologies in the oral and maxillofacial regions in children and adolescents of a Brazilian population.

    abstract:BACKGROUND:Few studies regarding the distribution of pediatric oral diseases are available. Thus, the aim of this study was to investigate the incidence and demographic profile of neoplasms and non-neoplastic lesions among children and adolescents (0-19 years old). METHODS:A retrospective descriptive cross-sectional s...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-018-2581-0

    authors: da Silva Barros CC,da Silva LP,Gonzaga AKG,de Medeiros AMC,de Souza LB,da Silveira ÉJD

    更新日期:2019-04-01 00:00:00

  • Multifactorial logistic regression analysis of factors associated with the incidence of erosive tooth wear among adults at different ages in Tokyo.

    abstract:OBJECTIVES:The aim of this study was to evaluate factors associated with the incidence of erosive tooth wear (ETW) among adults at different ages in Tokyo using multifactorial logistic regression analysis. MATERIALS AND METHODS:The study sample consisted of a total of 1108 subjects aged 15 to 89 years in Tokyo, Japan....

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-017-2065-7

    authors: Kitasako Y,Sasaki Y,Takagaki T,Sadr A,Tagami J

    更新日期:2017-11-01 00:00:00

  • Orthodontic cell stress modifies proinflammatory cytokine expression in human PDL cells and induces immunomodulatory effects via TLR-4 signaling in vitro.

    abstract:OBJECTIVE:Biomechanical orthodontics loading of the periodontium initiates a cascade of inflammatory signaling events that induce periodontal remodeling and finally facilitate orthodontic tooth movement. Pattern recognition receptors such as toll-like receptors (TLRs) have been well characterized for their ability to i...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-019-03111-8

    authors: Marciniak J,Lossdörfer S,Knaup I,Bastian A,Craveiro RB,Jäger A,Wolf M

    更新日期:2020-04-01 00:00:00

  • Evaluation of selective caries removal in deciduous teeth by a fluorescence feedback-controlled Er:YAG laser in vivo.

    abstract::This study investigated the ability and efficacy of an Er:YAG laser with a fluorescence feedback system for caries removal in deciduous teeth. Seventy-nine carious lesions were excavated using a fluorescence-controlled Er:YAG laser. Endpoint of treatment was defined by emission of fluorescence from the dentine surface...

    journal_title:Clinical oral investigations

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00784-007-0169-1

    authors: Krause F,Braun A,Lotz G,Kneist S,Jepsen S,Eberhard J

    更新日期:2008-09-01 00:00:00

  • Electromyographic activity of superficial masseter and anterior temporal muscles during unilateral mastication of artificial test foods with different textures in healthy subjects.

    abstract:OBJECTIVES:This study aimed to examine the electromyographic activity of superficial masseter and anterior temporal muscles during chewing gum and gummy jelly mastication in healthy subjects to reveal the difference of neuromuscular control of jaw-closing muscles, according to the food texture. MATERIALS AND METHODS:E...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-018-2754-x

    authors: Tomonari H,Seong C,Kwon S,Miyawaki S

    更新日期:2019-09-01 00:00:00

  • Identification and characterization of estrogen-like components in commercial resin-based dental restorative materials.

    abstract::Recently, resin-based dental restorative materials have been targeted as potential sources of xenoestrogens, specifically bisphenol A (BPA) and bisphenol A dimethacrylate (BAD), which could contribute to overall estrogen load and result in deleterious side effects. The present study used high-pressure liquid chromatog...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s007840050087

    authors: Lewis JB,Rueggeberg FA,Lapp CA,Ergle JW,Schuster GS

    更新日期:1999-09-01 00:00:00

  • Correction to: The effects of a novel herbal toothpaste on salivary lactate dehydrogenase as a measure of cellular integrity.

    abstract::In the original version of this article, the following were noted for correction. ...

    journal_title:Clinical oral investigations

    pub_type: 已发布勘误

    doi:10.1007/s00784-020-03657-y

    authors: Sreenivasan PK,Kakarla VVP,Sharda S,Setty Y

    更新日期:2020-10-26 00:00:00

  • Development of a validated process for manual preparation of dental transmission instruments.

    abstract::The goal of the study was to develop a validated manual preparation process that conforms to the requirements of validation guidelines. Twelve dental transmission devices from various manufacturers (turbines, handpieces, and contra-angle handpieces) were artificially contaminated with bovine hemoglobin for the test. T...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-010-0425-7

    authors: Büchter A,Kruse-Loesler B

    更新日期:2011-10-01 00:00:00

  • Analysis of the intraimplant microflora of two-piece dental implants.

    abstract:OBJECTIVE:Information about the spectrum of microorganisms in the intraimplant cavities of two-piece dental implants is scarce. The purpose of this study was to assess the intraimplant microflora of two-piece dental implants by conventional biochemical testing, matrix-assisted laser desorption/ionization time-of-flight...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-012-0805-2

    authors: Harder S,Podschun R,Grancicova L,Mehl C,Kern M

    更新日期:2013-05-01 00:00:00

  • Two-year clinical evaluation of composite resins in non-carious cervical lesions.

    abstract:OBJECTIVE:The purpose of this double-blind, randomised trial was to compare the clinical performance of a hybrid composite (Clearfil AP-X, Kuraray, Tokyo) and a nanocomposite (Filtek Z350, 3M ESPE, St. Paul, MN) over a period of 2 years in non-carious class V lesions using a modified US Public Health Service (USPHS) sy...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00784-012-0780-7

    authors: Qin W,Song Z,Ye YY,Lin ZM

    更新日期:2013-04-01 00:00:00

  • Analgesia (mis)usage on a dental emergency service: a patient survey.

    abstract:OBJECTIVES:Analgesics are one of the most frequently used medicines. Self-medication and misuse have been described in the literature. The purpose of this study was to document analgesic (mis)use in a population seeking emergency dental treatment. MATERIAL AND METHODS:Patients consulting a dental emergency service wer...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-017-2228-6

    authors: Hommez G,Ongena B,Cauwels RGEC,De Paepe P,Christiaens V,Jacquet W

    更新日期:2018-04-01 00:00:00

  • A retrospective comparison of three modalities for vestibuloplasty in the posterior mandible: apically positioned flap only vs. free gingival graft vs. collagen matrix.

    abstract:OBJECTIVES:This work aimed to comparatively evaluate the three modalities of vestibuloplasty around implants in the posterior mandible. MATERIALS AND METHODS:Forty patients who presented with a shallow vestibule and insufficient keratinized gingiva were divided into three groups: apically positioned flap only (APF gro...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章

    doi:10.1007/s00784-017-2320-y

    authors: Lim HC,An SC,Lee DW

    更新日期:2018-06-01 00:00:00