Abstract:
OBJECTIVE:This study aimed to compare (18)F-fluorodesoxyglucose positron emission tomography/MRI ((18)F-FDG-PET-MRI) fusion images, including diffusion-weighted imaging (DWI), (18)F-FDG-PET/CT, and ultrasound (US) regarding their performance in nodal staging of patients with head and neck squamous cell carcinoma (HNSCC). MATERIALS AND METHODS:Eighteen patients prospectively underwent ultrasound examination, (18)F-FDG- PET/CT, and MRI before oral tumor resection and bilateral neck dissection. PET data sets were fused with contrast-enhanced T1-weighted MR images. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy for nodal detection were calculated for all the imaging modalities. Furthermore, the accuracy of the correct N-staging was calculated for all methods. Detailed histopathology served as the standard of reference. RESULTS:The sensitivity, specificity, PPV, NPV, and accuracy for detection of lymph node metastases were 63, 99, 86, 96, and 95 % for ultrasound; 30, 97, 56, 92, and 90 % for (18)F-FDG-PET/CT; 52, 96, 59, 94, and 91 % for (18)F-FDG-PET-MRI; and 53, 97, 67, 95, and 92 % for (18)F-FDG-PET-MRI plus DWI, respectively. There was no significant difference in the diagnostic accuracy for lymph node metastasis detection between (18)F-FDG-PET-MRI and (18)F-FDG-PET/CT (p = 0.839) and between (18)F-FDG-PET-MRI plus DWI and (18)F-FDG-PET/CT (p = 0.286), respectively. US was significantly more accurate than (18)F-FDG-PET/CT (p = 0.009), whereas no significant difference was seen between (18)F-FDG-PET-MRI and US (p = 0.223) or (18)F-FDG-PET-MRI plus DWI and US (p = 0.115). The nodal stage was correctly rated by (18)F-FDG-PET-MRI in eight patients, (18)F-FDG-PET-MRI plus DWI in nine patients, US in 12 patients, and (18)F-FDG-PET/CT in five out of 18 patients. CONCLUSION:Software-based fusion of (18)F-FDG-PET-MRI and (18)F-FDG-PET-MRI plus DWI may not increase nodal detection and N-staging performance in patients with oral malignancies compared to US and (18)F-FDG-PET/CT. CLINICAL RELEVANCE:Surgical staging of cervical lymph nodes will not be replaced even by advanced imaging modalities in the near future.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Heusch P,Sproll C,Buchbender C,Rieser E,Terjung J,Antke C,Boeck I,Macht S,Scherer A,Antoch G,Heusner TA,Handschel Jdoi
10.1007/s00784-013-1050-zsubject
Has Abstractpub_date
2014-04-01 00:00:00pages
969-78issue
3eissn
1432-6981issn
1436-3771journal_volume
18pub_type
杂志文章abstract:OBJECTIVE:The study aimed to evaluate the effect of internal silver coating as a countermeasure to crestal bone loss around implants with or without multiple abutment disconnections/reconnections. MATERIALS AND METHODS:Following tooth extraction, 48 implants with connected healing abutments (24 implants internally coa...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03416-z
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVES:This study was established to investigate whether the chemokines CXCL1, CCL2, and CCL5 are produced in periodontal cells and tissues and, if so, whether their levels are regulated by microbial and/or mechanical signals. MATERIALS AND METHODS:The chemokine expression and protein levels in gingival biopsies f...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03244-1
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to investigate the caries-preventive effect of newly developed fluoride and fluoride-free toothpastes specially designed for erosion prevention. The hypothesis was that these products might also show superior caries-inhibiting effect than regular fluoride toothpastes, since they were...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1789-0
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:Postoperative pain management is of highest interest for patients undergoing maxillofacial surgery including microvascular reconstructive surgery. Currently, there is a lack of information regarding process and outcome of postoperative pain management after microvascular reconstruction. MATERIALS AND METHOD...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1809-0
更新日期:2017-01-01 00:00:00
abstract::In the original version of this article, the following were noted for correction. ...
journal_title:Clinical oral investigations
pub_type: 已发布勘误
doi:10.1007/s00784-020-03657-y
更新日期:2020-10-26 00:00:00
abstract:OBJECTIVES:To evaluate denosumab, a human monoclonal antibody that mimics the effects of osteoprotegerin in bone metabolism, as a topical treatment of root surface to be used prior to delayed tooth replantation. MATERIALS AND METHODS:Thirty-six rats' right incisors were used. Teeth were extracted and divided into: del...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03430-1
更新日期:2020-07-29 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess whether alveolar ridge preservation (ARP) can reduce the need of ridge augmentation at posterior tooth sites. MATERIAL AND METHODS:This study enrolled patients who received dental implants at posterior tooth sites during 2013-2019. Demographic data and dental treatment hi...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-021-03778-y
更新日期:2021-01-11 00:00:00
abstract::The aim of this study was to investigate the different variables in mesio-vertically positioned impacted or erupted third molars in a group of volunteers in Turkey to determine the angular changes and levels of eruption radiographically using standardised panoramic radiographs. There were 213 volunteers with impacted ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-001-0144-1
更新日期:2002-06-01 00:00:00
abstract:OBJECTIVES:This study evaluated the danger zone (DZ) in mesial roots of mandibular molars and the correlation between anatomical references of the DZ and some anatomical landmarks including tooth/root length, depth of mesial and distal grooves, and inter-canal orifices distance. MATERIAL AND METHODS:Twenty-eight mesia...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03686-7
更新日期:2020-11-24 00:00:00
abstract:OBJECTIVES:Facial asymmetries in oculoauriculovertebral spectrum (OAVS) patients might require surgical corrections that are mostly based on qualitative approach and surgeon's experience. The present study aimed to develop a quantitative 3D CT imaging-based procedure suitable for maxillo-facial surgery planning in OAVS...
journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s00784-015-1660-8
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to investigate different fluorescence-based, two-color viability assays for visualization and quantification of initial bacterial adherence and to establish reliable alternatives to the ethidium bromide staining procedure. MATERIALS AND METHODS:Bacterial colonization was att...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0792-3
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:The aim of this in vitro study was to compare fluorescence-aided caries excavation with conventional excavation based on the Martens and Vickers hardness of dentin at the cavity floor after caries removal. MATERIALS AND METHODS:In total, 20 extracted human teeth with dentin caries were bisected through the l...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-0999-y
更新日期:2014-01-01 00:00:00
abstract::This study evaluated the colour parameters of composite and ceramic shade guides determined using a colorimeter and digital imaging method with illuminants at different colour temperatures. Two different resin composite shade guides, namely Charisma (Heraeus Kulzer) and Premise (Kerr Corporation), and two different ce...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-009-0329-6
更新日期:2010-12-01 00:00:00
abstract::The aim of this study was to evaluate the clinical long-term performance of a visible light-cured resin (VLCR) denture base material and to compare it to a well-established polymethylmethacrylate (PMMA)-based denture acrylic in a randomized split-mouth clinical long-term study. One hundred removable partial dentures i...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-011-0572-5
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:The purpose of this double-blind, randomised trial was to compare the clinical performance of a hybrid composite (Clearfil AP-X, Kuraray, Tokyo) and a nanocomposite (Filtek Z350, 3M ESPE, St. Paul, MN) over a period of 2 years in non-carious class V lesions using a modified US Public Health Service (USPHS) sy...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-012-0780-7
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVES:Root canal treatment failures often correlate with persistent biomaterial-associated endodontic infections. The aim of the present study was to assess the impact of endodontic obturation material sampling from root canals with posttreatment apical periodontitis on improving standard study protocols. MATERIA...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1231-4
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the 12-year clinical performance of sintered (Duceram, Dentsply-Degussa, Dentsply International Inc., PA, USA)-D and pressable (IPS Empress, Ivoclar-Vivadent, Schaan, Leichtenstein)-IPS ceramic inlay and onlay restorations. METHODS:Eighty-six restorations were placed in...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1669-z
更新日期:2016-09-01 00:00:00
abstract::The aim of this study was to compare the short-term performance of a session of single photodynamic therapy (PDT) and of a conventional ultrasonic debridement (UST) in persistent pockets of maintenance patients. In a prospective, randomized, controlled, single-blind clinical study, patients with chronic periodontitis ...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-009-0347-4
更新日期:2010-12-01 00:00:00
abstract::The aim of this study was to compare different methods of detection of Helicobacter pylori (H. pylori) in the dental plaque of dyspeptic patients. After recording the clinical indices, culture and polymerase chain reaction (PCR) methods were performed on plaque samples, while rapid urease test in addition to these tes...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-007-0104-5
更新日期:2007-09-01 00:00:00
abstract::The objective was to evaluate the development of oral health-related quality of life (OHRQoL) in patients with complete dentures and the association between OHRQoL and patient satisfaction. Fifty-two patients (mean age, 66.3, 48.1% male) received dentures in at least one jaw. The analysis was conducted on participants...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-010-0483-x
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVES:To compare selective COX-2 inhibitors with ibuprofen in terms of analgesia, rescue medication consumption, and adverse effects after impacted third molar removal. MATERIALS AND METHODS:Electronic databases were searched. Single dose, double-blind, randomized, and controlled clinical trials comparing the ana...
journal_title:Clinical oral investigations
pub_type: 杂志文章,meta分析
doi:10.1007/s00784-019-02910-3
更新日期:2020-01-01 00:00:00
abstract::The translucency of teeth allows the non-destructive subsurface visualisation of their microstructure by confocal laser scanning microscopy (CLSM) at a level of about 150 microns below the surface. The dentine-enamel junction (DEJ) is accessible only directly adjacent to the cervix of the tooth. Therefore teeth have t...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840050038
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVES:The purpose of this case series was to evaluate the new bone formation following guided bone regeneration (GBR) with a calcium phosphosilicate (CPS), alloplastic bone putty at peri-implant dehiscence defects and to assess survival rate of implants placed in the augmented sites after 12 months of function. M...
journal_title:Clinical oral investigations
pub_type: 杂志文章,多中心研究
doi:10.1007/s00784-014-1268-4
更新日期:2015-03-01 00:00:00
abstract::This study aims to evaluate the inclinations of right and left sides the mandibular fossa in Asian population using computed tomography (CT) images and determine its effects according to the parameters of gender, age, and asymmetry. CT images of the heads of 198 Asian subjects [95 females aged 44.2 ± 20.7 years, range...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0518-y
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVES:The present dental bleaching case report describes a new method that precisely quantifies the daily wearing-times of the bleaching product by inserting a microsensor in the acetate custom tray. The bleaching efficacy was also discussed since the patient was previously submitted to enamel microabrasion. METH...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2439-5
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the periodontal healing pattern of dehiscence-type defects following different chemical root conditioning modalities. MATERIALS AND METHODS:Buccal osseous dehiscence defects were created on six teeth of seven dogs. After dental plaque accumulation, defects were tr...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0848-4
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVES:The study aimed at assessing, as primary objective, the periapical status and quality of root fillings, and, as secondary objective, the endodontic treatment need of a German urban population in a cross-sectional study 20 years after the first one. MATERIALS AND METHODS:Clinical and radiographic data of 353...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2566-z
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:To evaluate the effects of air-blowing time and storage time on microtensile bond strength (μTBS) of universal adhesives to dentin. MATERIALS AND METHODS:Ninety flat dentin surfaces from extracted human third molars were bonded with three universal adhesives (Clearfil Universal Bond-CU; G-Premio Bond-GP; Sc...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2656-y
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVES:Analgesics are one of the most frequently used medicines. Self-medication and misuse have been described in the literature. The purpose of this study was to document analgesic (mis)use in a population seeking emergency dental treatment. MATERIAL AND METHODS:Patients consulting a dental emergency service wer...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2228-6
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVES:Recently, novel biphasic calcium phosphate (BCP) scaffolds have emerged as a new class of bone grafts with osteoinductive potential demonstrating the ability to form ectopic bone in extra-skeletal sites. The aim of the present study was to perform an osteogenic gene array to target possible genes responsible...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1825-0
更新日期:2017-04-01 00:00:00