Abstract:
OBJECTIVES:To compare selective COX-2 inhibitors with ibuprofen in terms of analgesia, rescue medication consumption, and adverse effects after impacted third molar removal. MATERIALS AND METHODS:Electronic databases were searched. Single dose, double-blind, randomized, and controlled clinical trials comparing the analgesic effect of a selective COX-2 inhibitor versus at least one active control group using ibuprofen after impacted third molar removal were selected. RESULTS:Twelve studies were included for the qualitative synthesis and eight were included in the meta-analysis. No statistically significant differences were found between selective COX-2 inhibitors and ibuprofen in terms of pain relief after 6, 8, and 12 h. Rescue analgesia use after 24 h was significantly greater in the ibuprofen group than in the selective COX-2 inhibitor group. There were no statistically significant differences in the number of patients presenting one or more adverse events between the two groups, though ibuprofen intake was related with more nausea and vomiting. CONCLUSIONS:No statistically significant differences were found in terms of pain relief 6, 8, and 12 h post-medication between selective COX-2 inhibitors and ibuprofen following totally or partially impacted third molar removal. The patients who consumed selective COX-2 inhibitors needed less rescue analgesia after 24 h. The occurrence of one or more adverse events was similar in both groups, though patients who consumed ibuprofen had more nausea and vomiting. CLINICAL RELEVANCE:COX-2 inhibitors could be considered a suitable alternative to ibuprofen for pain relief after third molar extraction in patients at risk of developing nausea and vomiting. Also, COX-2 inhibitors seem to slightly reduce the need of rescue medication consumption.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
González-Barnadas A,Camps-Font O,Martín-Fatás P,Figueiredo R,Gay-Escoda C,Valmaseda-Castellón Edoi
10.1007/s00784-019-02910-3subject
Has Abstractpub_date
2020-01-01 00:00:00pages
79-96issue
1eissn
1432-6981issn
1436-3771pii
10.1007/s00784-019-02910-3journal_volume
24pub_type
杂志文章,meta分析abstract:OBJECTIVES:We evaluated the effects of low-level laser therapy (LLLT) using an infrared laser (IRL) and a red laser (RL) on the pulp of molar teeth in rats after dental bleaching to assess inflammation, collagen fiber maturation, and tertiary dentin formation. MATERIALS AND METHODS:Eighty Wistar rats (Rattus norvegicu...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03258-9
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to introduce a novel three-dimensional (3D) method to quantify the relative amount of different tissue components in bone substitute-treated defects by means of integration of confocal laser imaging into micro-computed tomography (μCT) analysis. MATERIALS AND METHODS:One standardize...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1081-5
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:To identify predictors in patient profiles, and to develop, internally validate, and calibrate prediction models for the persistence of self-reported orofacial pain at the 6-month and 12-month follow-up in patients with myofascial pain. MATERIALS AND METHODS:A cohort of 63 adult patients with moderate to se...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03570-4
更新日期:2020-09-10 00:00:00
abstract:OBJECTIVES:Previous research revealed that autogenous tooth roots may be biologically equivalent to conventional bone grafts for lateral ridge augmentation. However, these analyses were limited to two dimensions, whereas healing is a volumetric process. The present study aimed at volumetrically assessing the microstruc...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2723-4
更新日期:2019-07-01 00:00:00
abstract::The effect of fluoride released by bioadhesive tablets was evaluated in an in situ model in human volunteers. Eight volunteers carried four to six polished human enamel samples in a lower lingual device for a period of 5 days without fluoride supplements (control) and 5 days using one bioadhesive tablet (0.5 mg F) per...
journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s007840000076
更新日期:2000-09-01 00:00:00
abstract::The hypotheses tested were: survival rate of fully and partially retained glass-carbomer sealants is higher than those of high-viscosity glass-ionomer, with and without energy supplied, and that of resin composite; survival rate of fully and partially retained sealants of high-viscosity glass-ionomer with energy suppl...
journal_title:Clinical oral investigations
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00784-011-0633-9
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:Several theories have been proposed regarding the genesis of sialoliths, including the organic core theory, which suggests epithelial or bacterial etiology originating in the central core. Our aim was to use novel methodologies to analyze central areas (the core) of calculi from sialolithiasis patients. MAT...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0870-6
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVES:This study examines accuracy of dental impressions and following plaster models taken during treatment with fixed appliances. MATERIALS AND METHODS:A maxillary typodont was provided with brackets. Three examiners took impressions three times each of the variants: brackets only, archwire fixed by alastics, l...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1514-4
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:The clinical standard for alveolar cleft osteoplasty is augmentation with autologous bone being available in limited amounts and might be associated with donor site morbidity. The aim of the present study was the creation of tissue-engineered bone grafts and their in vivo evaluation regarding their potential...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2050-1
更新日期:2017-11-01 00:00:00
abstract::Squamous cell carcinoma (SCC) of the oral cavity is an extremely invasive tumour of stratified squamous epithelium that spreads throughout degradation of the basement membrane (BM) and extra-cellular matrix. Oral verrucous carcinoma (VC) is a rare low-grade variant of oral SCC that penetrates into the subepithelial co...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-009-0296-y
更新日期:2010-06-01 00:00:00
abstract::Dear Professor Dr. Matthias Hannig. Editor-in-Chief Clinical Oral Investigations. Following the publication of our paper by Calvo Guirado et al, 2015 [1] in Clinical Oral Investigations, it came to light that a certain part of the text at the materials and methods and results sections were similar. ...
journal_title:Clinical oral investigations
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00784-018-2763-9
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:The aim of this investigation was to assess the currently available evidence concerning the complications and risk factors influencing the outcome of autotransplantation of teeth in humans. MATERIALS AND METHODS:Electronic searches were conducted to identify randomized controlled and prospective clinical tr...
journal_title:Clinical oral investigations
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00784-015-1473-9
更新日期:2015-07-01 00:00:00
abstract::In the course of a prospectively designed long-term clinical trial, composite fillings and inlays were evaluated for clinical acceptability as restorative materials in one, two or more surface cavities of posterior teeth over a 1-year period. In 45 patients, 88 restorations were placed by nine student operators, under...
journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章
doi:10.1007/s007840050013
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVES:To assess the internal and external morphologies of the mesiobuccal (MB) root of maxillary molars presenting a third root canal (MB3), using micro-computed tomography (micro-CT). MATERIAL AND METHODS:Two-hundred and sixty-five extracted maxillary first and second molars with different root configurations we...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03284-7
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVES:A multicentric randomized, 3-year prospective study was conducted to determine for how long Biodentine, a new biocompatible dentine substitute, can remain as a posterior restoration. MATERIALS AND METHODS:First, Biodentine was compared to the composite Z100®, to evaluate whether and for how long it could be...
journal_title:Clinical oral investigations
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00784-012-0701-9
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to validate the reproducibility and observer variability of the Functional Implant Prosthodontic Score (FIPS), while considering the level of dental experience for intra- and inter-examiner analysis. MATERIALS AND METHODS:A total of 44 examiners (n = 31 undergraduate dental student...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2332-7
更新日期:2018-07-01 00:00:00
abstract::This study evaluated by standardised digitised periapical radiography the crestal bone maintenance around modified diameter internal hex implants with variable thread design and narrow neck loaded with different procedures. Forty implants were placed in 25 patients. Twenty implants were conventionally loaded, 20 ones ...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-009-0314-0
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to compare the effect of one-stage full-mouth disinfection (FMD) and conventional quadrant scaling in four weekly sessions (QS) on periodontal clinical parameters and halitosis among individuals with advanced chronic periodontitis. MATERIALS AND METHODS:In this randomized cont...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-016-1959-0
更新日期:2017-06-01 00:00:00
abstract::This study compared shear bond strengths of six self-adhesive resin cements to zirconium oxide ceramic with and without air-particle abrasion. One hundred twenty zirconia samples were air-abraded (group SB; n = 60) or left untreated (group NO). Composite cylinders were bonded to the zirconia samples with either BisCem...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-009-0278-0
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVES:The aim of this study is to compare wound healing and patient pain perception of single-incision (single-incision, modified single-incision) and trap-door surgical techniques to harvest subepithelial connective tissue grafts from the palate. MATERIAL AND METHODS:Thirty-six patients were selected for root co...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1204-7
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVES:This study aims to test the influence of different surface treatments and conditioning on the shear bond strength between polyetherketone (PEEK) and composite. MATERIALS AND METHODS:Surfaces (570 plates) were used untreated, etched, air-particle abraded or activated with silica-modified alumina oxide. Surfa...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1294-2
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:Reconstruction of large and complex bone segments is a challenging problem facing maxillofacial surgery. The majority of current regenerative approaches rely on extrinsic vascularization, which is deficient after cancer ablation and irradiation. The aim of the study was to investigate the efficacy of intrinsi...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1143-8
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:Facial asymmetry is one of the main concerns in patients with a dentofacial deformity. The aims of the study were to (1) evaluate the changes in facial asymmetry after bimaxillary surgery for asymmetric skeletal class II deformity and (2) compare preoperative and postoperative facial asymmetry of class II pa...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2462-6
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVES:Evaluate the effects of ionizing radiation on microarchitecture, the osteocyte lacunar network, and collagen maturity in a bone repair site. MATERIALS AND METHODS:Bone defects were created on tibias of 20 New Zealand rabbits. After 2 weeks, the animals were randomly divided into (n = 10) NoIr (nonirradiated...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03138-x
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:Edible oils are an empiric approach for the prevention of oral diseases. The present in situ study investigated the effect of edible oils on initial bacterial colonization of enamel surfaces. METHODS AND MATERIALS:Initial biofilm formation was performed on enamel specimens mounted on maxillary splints and ca...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-012-0734-0
更新日期:2013-03-01 00:00:00
abstract::The aim of this study was to evaluate the clinical performance of S(3) Bond (Kuraray Corp., Japan) and G-Bond (GC Corp., Japan) all-in-one bonding agents, over 3 years in non-carious cervical lesions (NCCLs). Ethics Committee approval was obtained, and 60 restorations were placed in 11 patients aged 45-84 years (mean ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0595-y
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:Geranylgeraniol (GGOH) has been reported as a potential treatment option for bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ). The aim of this study was to analyze the effects of GGOH on endothelial progenitor cells (EPC) after bisphosphonate treatment in vitro. MATERIALS AND METHODS:EPC were in...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1394-z
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:This study investigated the effect of passive ultrasonic irrigation (PUI) on diffusion of hydroxyl ions through radicular dentine. MATERIALS AND METHODS:After chemomechanical preparation of root canals in 60 human teeth, the cementoenamel junction and the apical 3 mm of each root were covered with fast-setti...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1500-x
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the effect of different endodontic solvents on the microtensile bond strength (μTBS) of various adhesives to pulp chamber dentin. MATERIAL AND METHODS:A total of 120 human third molars were selected. Canals were prepared with the ProTaper Universal system and obturated....
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1929-6
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to compare temperature variation during osteotomies with trephine drills under different irrigation conditions: without irrigation, external irrigation, and double irrigation. MATERIALS AND METHODS:Synthetic blocks of bone (type I density) were used for drilling procedures with ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1163-4
更新日期:2014-09-01 00:00:00