Abstract:
BACKGROUND:Few studies regarding the distribution of pediatric oral diseases are available. Thus, the aim of this study was to investigate the incidence and demographic profile of neoplasms and non-neoplastic lesions among children and adolescents (0-19 years old). METHODS:A retrospective descriptive cross-sectional study was performed and data regarding gender, age, anatomical location, and histopathological diagnosis were collected and categorized. Biopsy records were obtained from the archives of a Brazilian referral center between 1980 and 2016. RESULTS:A total of 2.114 pediatric patient biopsy records were analyzed, where most cases were diagnosed in patients aged 10 to 19 years old (80.7%). Females were more affected (n = 1180) and the lip (n = 507) was the most common anatomical site. Reactive and inflammatory lesions (n = 942) were the most prevalent non-neoplastic pathologies, followed by cysts (n = 308). Benign neoplasms were the most frequent among neoplasms (n = 346) and malignant cases were very rare (n = 11). CONCLUSIONS:An increase in the prevalence of lesions in the second decade of life was observed, where reactive and inflammatory lesions, cysts, and benign neoplasms were most frequent. CLINICAL RELEVANCE:Biopsy data allows for the real characterization of the incidence of oral and maxillofacial lesions and, thus, permits Brazilian dentists and pediatricians to diagnose these diseases.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
da Silva Barros CC,da Silva LP,Gonzaga AKG,de Medeiros AMC,de Souza LB,da Silveira ÉJDdoi
10.1007/s00784-018-2581-0subject
Has Abstractpub_date
2019-04-01 00:00:00pages
1587-1593issue
4eissn
1432-6981issn
1436-3771pii
10.1007/s00784-018-2581-0journal_volume
23pub_type
杂志文章abstract:OBJECTIVES:A group of adolescents with oral piercings was studied to determine the presence of metallic particles in cells exfoliated from the mucosa surrounding their metal oral piercings and the association between such particles and the metal jewelry, and to evaluate subsequent tissue implications. MATERIALS AND ME...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2626-4
更新日期:2019-04-01 00:00:00
abstract::The present study focuses on the correlation between the expression pattern of β-catenin (component of Wnt signaling), ΔNp63 (proliferation marker), and Notch 1 (transmembrane receptor) in oral squamous cell carcinoma. The study also aims to investigate the interaction between β-catenin and ΔNp63 in oral cancer. Furth...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0605-0
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:Emdogain, containing an extract of fetal porcine enamel matrix proteins, is a potent stimulator of in vitro osteoclastogenesis. The underlying molecular mechanisms are, however, unclear. MATERIAL AND METHODS:Here, we have addressed the role of transforming growth factor-beta receptor type 1 (TGF-βRI) kinase...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1129-6
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:Ex-vivo evaluation of the detectability of vertical root fractures (VRFs) using digital subtraction radiography (DSR) and conventional digital periapical radiography (CDPR); investigation of the effect of root canal filling, x-ray angulation, and thickness of the VRF in the diagnostic accuracy. MATERIALS AND...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03245-0
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:The aim of this in vitro study was to compare fluorescence-aided caries excavation with conventional excavation based on the Martens and Vickers hardness of dentin at the cavity floor after caries removal. MATERIALS AND METHODS:In total, 20 extracted human teeth with dentin caries were bisected through the l...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-0999-y
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To establish the association between adipokine levels and markers of periodontal involvement as risk indicators of early stages of RA (eRA) and the interaction between the presence of markers of periodontal disease with adipokine in eRA individuals. MATERIALS AND METHODS:Fifty-one patients with a diagnosis o...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03469-0
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to investigate different fluorescence-based, two-color viability assays for visualization and quantification of initial bacterial adherence and to establish reliable alternatives to the ethidium bromide staining procedure. MATERIALS AND METHODS:Bacterial colonization was att...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0792-3
更新日期:2013-04-01 00:00:00
abstract::The aim of this study was to evaluate the influence of caries-detecting dyes on the microleakage of adhesive materials. Sixty cubic class V cavities were prepared on buccal and lingual surfaces of 30 human third molars. Coronal margins were located in enamel and gingival margins in cementum. The teeth were randomly di...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-002-0182-3
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess whether and how the information obtained by means of cone beam computed tomography (CBCT) on maxillary posterior teeth differs from that obtained by panoramic radiography. MATERIALS AND METHOD:From 157 subjects (mean age 48 years, range 19-84 years; 89 females) referre...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-0963-x
更新日期:2014-01-01 00:00:00
abstract:AIM:The primary objective of this study was (1) to evaluate the 5-year clinical outcome of regenerative periodontal therapy (RPT) using minimally invasive surgery and a collagen-enriched bovine-derived xenograft and (2) to identify predictors for clinical attachment level (CAL) gain and vertical radiographic bone (RB) ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2208-x
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVES:This prospective randomized clinical trial aimed to evaluate the long-term behavior of metal-free double crown retained dentures with secondary crowns and dental frameworks made of the fiber-reinforced composite Vectris(©) on all-ceramic primary crowns (IPS Empress 2(©)) over a period of up to 14 years and t...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-015-1597-y
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:This study aimed to evaluate whether a specific interleukin-1 receptor-associated kinase-4 (IRAK4) gene polymorphism had any influence on the development of changes in maxillary sinus, particularly in the presence of etiological factors of dental origin. MATERIALS AND METHODS:The study population included 1...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1424-5
更新日期:2015-11-01 00:00:00
abstract::The aim of the study was the morphological analysis of coronal dentin caries and the modifications induced by different pretreatments with phosphoric acid or sodium hypochlorite. Carious dentin specimens were obtained from human molars affected by carious lesions. Specimens were divided in four groups and submitted to...
journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00784-003-0221-8
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the effect of simulated gastric acid solution on surface topography and bending properties of esthetic coated nickel-titanium (NiTi) archwires. MATERIALS AND METHODS:Three brands of as-received white-coated superelastic NiTi upper archwires were used in this study: D...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03438-7
更新日期:2020-07-03 00:00:00
abstract:OBJECTIVES:Platelet-rich plasma has been used in the treatment of extraction socket; however, randomized controlled clinical trial is still lacking to evaluate its effect on extraction socket healing. MATERIALS AND METHODS:Single center, assessor-blinded, parallel group, randomized controlled clinical trial was conduc...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-014-1278-2
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVES:To identify predictors in patient profiles, and to develop, internally validate, and calibrate prediction models for the persistence of self-reported orofacial pain at the 6-month and 12-month follow-up in patients with myofascial pain. MATERIALS AND METHODS:A cohort of 63 adult patients with moderate to se...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03570-4
更新日期:2020-09-10 00:00:00
abstract::Aim of this investigation was to evaluate the validity and reproducibility of the universal visual scoring systems (UniViSS) on occlusal surfaces in vitro. The validity study included 65 third molars. Following to reach a UniViSS consensus diagnosis for each surface, all teeth were histologically prepared and evaluate...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-010-0390-1
更新日期:2011-04-01 00:00:00
abstract::The goal of the study was to develop a validated manual preparation process that conforms to the requirements of validation guidelines. Twelve dental transmission devices from various manufacturers (turbines, handpieces, and contra-angle handpieces) were artificially contaminated with bovine hemoglobin for the test. T...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-010-0425-7
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to examine the influence of experience and gender on the radiographic detection of proximal caries lesions and on therapeutic decisions. MATERIALS AND METHODS:A survey of 220 examiners (students and employees at three universities and dentists in the field) was taken using a standa...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2078-2
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:Intrapapillary injection (IPI) has been suggested to improve pulpal anesthesia of mandibular teeth and to avoid complications from inferior alveolar nerve block (IANB). This study aimed to determine and compare clinical efficacies and prostaglandin E2 (PGE2) levels between IPI and IANB. MATERIALS AND METHODS...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-019-02954-5
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate factors associated with the incidence of erosive tooth wear (ETW) among adults at different ages in Tokyo using multifactorial logistic regression analysis. MATERIALS AND METHODS:The study sample consisted of a total of 1108 subjects aged 15 to 89 years in Tokyo, Japan....
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2065-7
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was the qualitative and quantitative evaluation of osseous graft consolidation using allogeneic bone blocks for vertical bone augmentation in an animal model. MATERIAL AND METHODS:Standardised allogeneic and autologous bone blocks were fixed on the frontal skull of 20 adult fema...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03151-0
更新日期:2020-08-01 00:00:00
abstract::The purpose of the present study was to decide whether composite resin or conventional glass ionomer cement should be preferred as a base material in endodontically treated premolars. Twelve extracted human maxillary premolars were mounted in a universal testing machine at a 35 degrees angle. Cuspal stiffness was dete...
journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s007840050049
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVES:Cell-free DNA (cfDNA) harboring mutations has been found in patients with diseases. Experimental studies have shown that cfDNA can be transmitted, leading to transformations in the host. In the present study, we evaluated whether bone allograft material contains cfDNA and whether this foreign cfDNA can be re...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02867-3
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:Noninvasive optical methods such as photoplethysmography, established for blood pulse detection in organs, have been proposed for vitality testing of human dental pulp. However, no information is available on the mechanism of action in a closed pulp chamber and on the impairing influence of other than pulpal ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1115-z
更新日期:2014-01-01 00:00:00
abstract::The goal of this investigation was to evaluate the effect of postoperative exposure of two different bioresorbable membranes on the guided tissue regeneration (GTR) healing results compared to nonexposed sites. In each of 25 patients one pair of contralateral intrabony lesions was treated either with polylactic acid (...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840050021
更新日期:1997-09-01 00:00:00
abstract::The present study compared the recovery of six periodontal pathogens by paper point samples from two different aspects of periodontal lesions by quantitative real-time polymerase chain reaction (PCR). Twenty patients with untreated chronic periodontitis were randomized into two groups. Before subgingival instrumentati...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-009-0333-x
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVES:Lithium disilicate can easily be machined by CAM techniques in its metasilicate status. Due to slightly inferior material properties, the material is not yet recommended for three-unit fixed dental prosthesis (FDP) as it is the case for the press material up to the second bicuspid. Therefore, the aim of this...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1191-8
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:The aim of this work was to evaluate the anti-inflammatory and antiresorptive effects of Calendula officinalis (CLO) on alveolar bone loss (ABL) in rats. MATERIAL AND METHODS:Male Wistar rats were subjected to ABL by ligature with nylon thread around the second upper left molar. The contralateral hemimaxilla...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2308-7
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:The aim of the present study is to evaluate the possible correlation between sealer penetration into dentinal tubules and sealing ability both in presence and absence of smear layer. MATERIALS AND METHODS:Fourteen maxillary central incisors were treated with 5.25 % NaOCl +10 % EDTA to remove the smear layer...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1878-0
更新日期:2017-05-01 00:00:00