Abstract:
OBJECTIVES:This in vitro study evaluated the effect of fiber insertion depth on antimicrobial efficacy of antimicrobial photodynamic therapy (aPDT) using a photosensitizer (PS; toluidine blue) and a red light-emitting diode (LED) in root canals infected with Enterococcus faecalis. MATERIALS AND METHODS:Single-rooted extracted teeth were prepared with nickel-titanium-instruments, sterilized, contaminated with E. faecalis, and incubated for 72 h. Roots were randomly divided into four experimental groups: PS only, LED only, aPDT with LED in the apical third, aPDT with LED in the coronal third, as well as into infection and sterile controls (each n = 10). Samples were taken by collecting standardized dentine shavings from the root canal walls. After serial dilution and culturing on blood agar, colony-forming units (CFU) were counted. RESULTS:Both aPDT groups showed a CFU reduction of 1-2 log10 steps compared with the infection control, whereas the effect of fiber insertion depth was negligible (<0.5 log10 steps). CFU reduction of approximately 0.5 log10 steps for PS alone was detected compared with the infection control, but PS alone was less effective than both aPDT groups. No antibacterial effect was detected for LED alone. CONCLUSIONS:aPDT reduced E. faecalis within the root canal, whereas fiber insertion depth had a negligible influence on antimicrobial effectiveness of aPDT. CLINICAL RELEVANCE:The insertion depth of the light-emitting diode may not influence the antibacterial efficacy of photodynamic therapy against E. faecalis in straight root canals.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Rödig T,Endres S,Konietschke F,Zimmermann O,Sydow HG,Wiegand Adoi
10.1007/s00784-016-1948-3subject
Has Abstractpub_date
2017-06-01 00:00:00pages
1753-1759issue
5eissn
1432-6981issn
1436-3771pii
10.1007/s00784-016-1948-3journal_volume
21pub_type
杂志文章abstract:OBJECTIVES:To assess the quality of clinical practice guidelines (CPGs) on screening and diagnosis of oral cancer and to describe the characteristics of their recommendations. MATERIALS AND METHODS:We systematically searched EMBASE, MEDLINE, CPG' websites, and dentistry and oncology scientific societies to identify CP...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2668-7
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE:Aggregatibacter actinomycetemcomitans, specially its highly leucotoxic strain (JP2 clone), represents an etiological factor for the onset and progression of aggressive types of periodontitis. The aims of this investigation were to investigate the most relevant periodontal pathogens in the subgingival microbio...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1653-7
更新日期:2016-09-01 00:00:00
abstract::The aim of the present study was to comparatively evaluate DNA damage (micronucleus) and cellular death (pyknosis, karyolysis, and karyorrhexis) in exfoliated oral mucosa cells from smokers and non-smokers submitted to dental X-ray using two anatomic sites: buccal mucosa and lateral border of the tongue. A total of 15...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-009-0345-6
更新日期:2010-12-01 00:00:00
abstract::The aims of this study were to evaluate clinically and microbiologically the effects of two resin-modified glass-ionomer cements (RMGICs) used as liners after incomplete dentine caries removal and to identify Streptococcus mutans and Streptococcus sobrinus strains isolated from dentine samples, before and after indire...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-009-0304-2
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVES:We sought to identify oral symptoms found in hyperparathyroidism and compare their rate of occurrence, as well as potential variations in sequelae between primary, secondary, and tertiary hyperparathyroidism. MATERIALS AND METHODS:Database searches were performed through EMBASE and PubMed, with a continual ...
journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s00784-017-2124-0
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:Investigate the biochemistry of in vivo healthy oral tissues through Raman spectroscopy. We aimed to characterize the biochemical features of healthy condition in oral subsites (buccal mucosa, lip, tongue, and gingiva) of healthy subjects. More specifically, we investigated Raman spectral characteristics and...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2714-5
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVES:This study aimed to investigate the effect of fracture orientation on the detection accuracy of vertical root fractures (VRFs) in non-endodontically treated teeth using four different cone beam computed tomography (CBCT) units. MATERIALS AND METHODS:Thirty eight out of 148 extracted human permanent teeth we...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02905-0
更新日期:2019-12-01 00:00:00
abstract::The alveolar cleft in patients with clefts of lip, alveolus and palate (CLAP) is usually reconstructed with an autologous bone graft. Harvesting of autologous bone grafts is associated with more or less donor site morbidity. Donor site morbidity could be eliminated if bone is fabricated by growth factor-aided tissue e...
journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s00784-011-0547-6
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:This study investigated the antibacterial properties and micro-hardness of polyacrylic acid (PAA)-coated copper iodide (CuI) nanoparticles incorporated into glass ionomer-based materials, and the effect of PAA-CuI on collagen degradation. MATERIALS AND METHODS:PAA-CuI nanoparticles were incorporated into gl...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1799-y
更新日期:2017-01-01 00:00:00
abstract::This retrospective study investigated the frequency and time history of chipping or facings failure of three-unit and four-unit tooth-supported metal ceramic (MC) fixed partial prostheses (FPDs). Six hundred fifty-four MC FPDs were inserted according to a standardized treatment protocol at the Department of Prosthodon...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0511-5
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare the palatal total support tissues (TSTs) and bone support tissues (BSTs) at 5-mm paramedian section to the midsagittal suture between mouth breathers with high-narrow palates and nose breathers with normal palates and confirm the practicability and limitation on superimpo...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03004-w
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:The objective of this in vitro study was to investigate fracture load, fracture types, and impact of chewing simulation of human molars restored with 3D printed indirect polyetheretherketone (PEEK) inlays and compare these with milled indirect PEEK inlays, direct resin composite fillings, and sound teeth. MA...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03216-5
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:To evaluate and compare the obturation quality of mineral trioxide aggregate (MTA) and Biodentine placed with hand condensation or indirect ultrasonic activation technique in teeth models simulating perforating internal root resorption (IRR) using micro-computed tomographic (micro-CT) imaging. MATERIALS AND...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2502-2
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVES:A group of adolescents with oral piercings was studied to determine the presence of metallic particles in cells exfoliated from the mucosa surrounding their metal oral piercings and the association between such particles and the metal jewelry, and to evaluate subsequent tissue implications. MATERIALS AND ME...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2626-4
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:The use of the autogenous periosteal graft as biological barrier has been proposed for periodontal regeneration. The aim of this study was to evaluate the histometric findings of the subepithelial connective tissue graft as barrier in intrabony defects compared to a bioabsorbable membrane. METHODS:Three-wal...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1323-1
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVES:The purpose of this systematic review was to examine if, in adult patients, the absence or presence of smoking influenced the prevalence of periapical periodontitis (PP). MATERIALS AND METHODS:Databases were searched, and original research manuscripts up to June 2019 were identified by two reviewers. The Ne...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03094-6
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:The aim was to study self-image and the level of psychological symptoms in patients with symptoms attributed to their dental restorative materials. MATERIALS AND METHODS:A questionnaire containing questions regarding dental and medical history was answered by 257 participants, one group with local oral symp...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2707-4
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:The aim of this prospective, randomized, clinical study was to assess the effect of photobiomodulation therapy (PBM) with low-level laser irradiation (LLLI) on postoperative pain after endodontic treatment. MATERIALS AND METHODS:Sixty patients, diagnosed with irreversible pulpitis in lower molar teeth, parti...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-018-2435-9
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:Albumin has a known capability to modulate free serum concentrations of proteins produced by tumour cells. The technique of spin probe labelling of albumin followed by electron paramagnetic resonance (EPR) spectroscopy may allow identification of these structural and functional changes, which regularly occur...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0655-3
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:Genome-wide association studies (GWAS) and literature have identified polymorphisms in the KCNJ11, HNF1A, IRS1, TCF7L2, CDKAL1, CDKN2B, RPSAP52, GPR45 HHEX, IL18, and RUNX2 genes associated with type 2 diabetes mellitus (T2DM) and/or periodontitis (P) in diverse populations, and we sought to evaluate them as ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03717-3
更新日期:2021-01-03 00:00:00
abstract:OBJECTIVES:This study aimed to investigate the root canal morphology of mandibular first premolar teeth in a population from southwestern China by micro-computed tomography (micro-CT). MATERIALS AND METHODS:Human mandibular first premolars (115) were selected and prepared for micro-CT analysis with a slice thickness o...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0778-1
更新日期:2013-04-01 00:00:00
abstract::Opisthorchis viverrini (O. viverrini; known as human liver fluke) is a major health problem in the northeastern region of Thailand. Infection with O. viverrini is the cause of hepatobiliary disease and cholangiocarcinoma (CCA). Previous studies demonstrated specific antibodies to crude O. viverrini antigens in serum f...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-010-0421-y
更新日期:2011-08-01 00:00:00
abstract::Complex human tissues harbour stem cells and/or precursor cells, which are responsible for tissue development or repair. Recently, dental tissues such as periodontal ligament (PDL), dental papilla or dental follicle have been identified as easily accessible sources of undifferentiated cells. The dental stem cell biolo...
journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s00784-007-0170-8
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the acidogenicity of dual-species biofilms of bifidobacteria and Streptococcus mutans. MATERIALS AND METHODS:The following strains were tested: Bifidobacterium dentium DSM20436, Parascardovia denticolens DSM10105, and Scardovia inopinata DSM10107. Streptococcus mutans UA...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1958-1
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:This aimed to assess the potential role of chronic stress in saliva secretion, xerostomia, and oral health in a population attending a saliva clinic. MATERIALS AND METHODS:Data of 114 patients who met the inclusion criteria and completed all questionnaires were analyzed in this study. Participants completed ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2393-2
更新日期:2018-12-01 00:00:00
abstract::The aim of this retrospective study was to determine the outcome of orthodontic treatment carried out on patients by postgraduate students at the Katholieke Universiteit Leuven, Belgium. The treatment outcome of 292 'final examination' patients and of 287 'control' patients was compared by means of the Peer Assessment...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840000094
更新日期:2001-03-01 00:00:00
abstract:INTRODUCTION:To compare, by Micro-CT and confocal laser scanning microscopy (CLSM), the ability of the Wave One Gold and Wave One systems to remove filling material from mesial canals of mandibular molars, effective time spent; quantity of extruded material, and percentage of sealer in the dentinal tubules after retrea...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2441-y
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To establish the association between adipokine levels and markers of periodontal involvement as risk indicators of early stages of RA (eRA) and the interaction between the presence of markers of periodontal disease with adipokine in eRA individuals. MATERIALS AND METHODS:Fifty-one patients with a diagnosis o...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03469-0
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:The aim of the present study is to provide a detailed macroscopic mapping of the palatal and tuberal blood supply applying anatomical methods and studying specific anastomoses to bridge the gap between basic structural and empirical clinical knowledge. MATERIALS AND METHODS:Ten cadavers (three dentate, seve...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2538-3
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to determine the prevalence of permanent first molar (P1M) extraction among Turkish adolescents and young adult subpopulation, and to investigate the effects of P1M extraction on development of the third molars (3Ms) in the same quadrant. MATERIALS AND METHODS:A retrospectiv...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1121-1
更新日期:2014-01-01 00:00:00