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Somatic stem cells for regenerative dentistry.

Abstract：

:Complex human tissues harbour stem cells and/or precursor cells, which are responsible for tissue development or repair. Recently, dental tissues such as periodontal ligament (PDL), dental papilla or dental follicle have been identified as easily accessible sources of undifferentiated cells. The dental stem cell biology might provide meaningful insights into the development of dental tissues and cellular differentiation processes. Dental stem cells could also be feasible tools for dental tissue engineering. Constructing complex structures like a periodontium, which provides the functional connection between a tooth or an implant and the surrounding jaw, could effectively improve modern dentistry. Dental precursor cells are attractive for novel approaches to treat diseases like periodontitis, dental caries or to improve dental pulp healing and the regeneration of craniofacial bone and teeth. These cells are easily accessible and, in contrast to bone-marrow-derived mesenchymal stem cells, are more closely related to dental tissues. This review gives a short overview of stem cells of dental origin.

journal_name

Clin Oral Investig

journal_title

Clinical oral investigations

authors

Morsczeck C,Schmalz G,Reichert TE,Völlner F,Galler K,Driemel O

doi

10.1007/s00784-007-0170-8

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

113-8

issue

2

eissn

1432-6981

issn

1436-3771

journal_volume

12

pub_type

杂志文章,评审

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