Apical pressure created during irrigation with the GentleWave™ system compared to conventional syringe irrigation.


OBJECTIVES:The purpose of this study is to compare pressures at the apical foramen created by conventional syringe irrigation and the GentleWave™ System, which releases high-velocity degassed irrigants to the pulp chamber and uses broad-spectrum sound energy for cleaning. MATERIALS AND METHODS:The apical pressure generated during irrigation was measured for palatal and distobuccal root canals of four extracted maxillary molars after no instrumentation, minimal instrumentation to a size #15/.04, instrumentation to a size #40/.04 taper, and after perforating the apical foramen to size #40. The root canals opened into an air-tight custom fixture coupled to a piezoresistive pressure transducer. Apical pressures were measured for the GentleWave™ System and syringe-needle irrigation at different irrigant flow rates, with the needle tip at 1 and 3 mm from the apical foramen using 30-gauge (G) open-ended or side-vented safety tip needles. RESULTS:The GentleWave™ System generated negative apical pressures (P < 0.001 compared with syringe irrigation); the mean pressures were between -13.07 and -17.19 mmHg. The 30 G needles could not reach the 1 and 3 mm from the working length in uninstrumented and 1 mm in minimally instrumented canals. The mean positive pressures between 6.46 and 110.34 mmHg were measured with needle irrigation depending on the flow rate, needle insertion depth, and size of the root canal. CONCLUSIONS:The GentleWave™ System creates negative pressure at the apical foramen during root canal cleaning irrespective of the size of canal instrumentation. Positive apical pressures were measured for syringe irrigation. CLINICAL RELEVANCE:Negative pressure during irrigation contributes to improved safety as compared to high-positive pressure.


Clin Oral Investig


Haapasalo M,Shen Y,Wang Z,Park E,Curtis A,Patel P,Vandrangi P




Has Abstract


2016-09-01 00:00:00














  • Study of temperature variation in cortical bone during osteotomies with trephine drills.

    abstract:OBJECTIVE:The purpose of this study was to compare temperature variation during osteotomies with trephine drills under different irrigation conditions: without irrigation, external irrigation, and double irrigation. MATERIALS AND METHODS:Synthetic blocks of bone (type I density) were used for drilling procedures with ...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Gehrke SA,Pazetto MK,de Oliveira S,Corbella S,Taschieri S,Mardegan FE

    更新日期:2014-09-01 00:00:00

  • Fit of 4-unit FDPs from CoCr and zirconia after conventional and digital impressions.

    abstract:OBJECTIVES:To evaluate the marginal and internal fit of CAD/CAM-generated frameworks for 4-unit, fixed dental prostheses (FDPs) from zirconia (Z) and cobalt-chromium alloy (C) made with conventional (CI) and digital impressions (DI). MATERIALS AND METHODS:A titanium model was digitized with an intraoral scanner (DI, L...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Ueda K,Beuer F,Stimmelmayr M,Erdelt K,Keul C,Güth JF

    更新日期:2016-03-01 00:00:00

  • Atraumatic restorative treatment-ART in early childhood caries in babies: 4 years of randomized clinical trial.

    abstract:OBJECTIVE:To assess the effectiveness of atraumatic restorative treatment (ART) performed 4 years ago in babies suffering from early childhood caries (ECC), and to compare the clinical performance of ART atraumatic restorations performed with two different high-viscosity glass ionomer cements (GIC). MATERIALS AND METH...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,随机对照试验


    authors: Faustino-Silva DD,Figueiredo MC

    更新日期:2019-10-01 00:00:00

  • Health services provision of 48 public tertiary dental hospitals during the COVID-19 epidemic in China.

    abstract:OBJECTIVES:To assess the status of health services provision of public tertiary dental hospitals during the COVID-19 epidemic in China and to evaluate the regional difference of telehealth. MATERIALS AND METHODS:The health services provision of public tertiary dental hospitals in China mainland during the COVID-19 epi...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Yang Y,Zhou Y,Liu X,Tan J

    更新日期:2020-05-01 00:00:00

  • The caries preventive effect of 1-year use of low-dose xylitol chewing gum. A randomized placebo-controlled clinical trial in high-caries-risk adults.

    abstract:OBJECTIVES:The caries preventive effect of long-term use (1 year) of low-dosage (2.5 g/die) of xylitol chewing gum in a high-caries-risk adult population was evaluated. MATERIALS AND METHODS:In this randomized clinical trial, 179 high-caries-risk adults were assigned to two experimental groups, xylitol and polyols. Ca...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,随机对照试验


    authors: Cocco F,Carta G,Cagetti MG,Strohmenger L,Lingström P,Campus G

    更新日期:2017-12-01 00:00:00

  • Surface characterization of passive film and elemental release analysis of a Ni-Cr alloy during bleaching, part I: effects of different bleaching agents.

    abstract::The aim of this study was to evaluate the elemental release from a Ni-Cr dental casting alloy subjected to 10% hydrogen peroxide (HP) or 10% carbamide peroxide (CP) solutions and to determine the composition of surface oxide layer formed on alloy samples. Cylinder-shaped 15 specimens were cast from a Ni-Cr alloy and d...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Tamam E,Aydın AK

    更新日期:2011-06-01 00:00:00

  • Screening and diagnosis of oral cancer: a critical quality appraisal of clinical guidelines.

    abstract:OBJECTIVES:To assess the quality of clinical practice guidelines (CPGs) on screening and diagnosis of oral cancer and to describe the characteristics of their recommendations. MATERIALS AND METHODS:We systematically searched EMBASE, MEDLINE, CPG' websites, and dentistry and oncology scientific societies to identify CP...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Madera M,Franco J,Solà I,Bonfill X,Alonso-Coello P

    更新日期:2019-05-01 00:00:00

  • Assessments of inclinations of the mandibular fossa by computed tomography in an Asian population.

    abstract::This study aims to evaluate the inclinations of right and left sides the mandibular fossa in Asian population using computed tomography (CT) images and determine its effects according to the parameters of gender, age, and asymmetry. CT images of the heads of 198 Asian subjects [95 females aged 44.2 ± 20.7 years, range...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Wu CK,Hsu JT,Shen YW,Chen JH,Shen WC,Fuh LJ

    更新日期:2012-04-01 00:00:00

  • Bisphosphonates inhibit cell functions of HUVECs, fibroblasts and osteogenic cells via inhibition of protein geranylgeranylation.

    abstract:OBJECTIVES:Bisphosphonate-associated osteonecrosis of the jaw is a severe side effect in patients receiving nitrogen-containing bisphosphonates (N-BPs). One characteristic is its high recurrence rate; therefore, basic research for new therapeutic options is necessary. N-BPs inhibit the farnesylpyrophosphate synthase in...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Hagelauer N,Ziebart T,Pabst AM,Walter C

    更新日期:2015-06-01 00:00:00

  • The perception of oral health and oral care needs, barriers and current practices as perceived by managers and caregivers in organizations for people with disabilities in Flanders, Belgium.

    abstract:OBJECTIVES:To assess the perception of oral health and oral care needs, barriers and current practices as perceived by managers and caregivers in organizations for people with disabilities in Flanders. MATERIALS AND METHODS:Two questionnaires were developed, one for managers and one for caregivers. The questionnaires ...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Phlypo I,Palmers E,Janssens L,Marks L,Jacquet W,Declerck D

    更新日期:2020-06-01 00:00:00

  • Comparison of two all-in-one adhesives bonded to non-carious cervical lesions--results at 3 years.

    abstract::The aim of this study was to evaluate the clinical performance of S(3) Bond (Kuraray Corp., Japan) and G-Bond (GC Corp., Japan) all-in-one bonding agents, over 3 years in non-carious cervical lesions (NCCLs). Ethics Committee approval was obtained, and 60 restorations were placed in 11 patients aged 45-84 years (mean ...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Burrow MF,Tyas MJ

    更新日期:2012-08-01 00:00:00

  • Preoperative imaging procedures for lower wisdom teeth removal.

    abstract::The aims of this paper were to critically review the role of radiographic imaging before lower third molar removal and to suggest a strategy for preoperative imaging based on available scientific evidence and clinical experience. Original articles and reviews including the MESH terms "third molar" and "radiography" we...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,评审


    authors: Flygare L,Ohman A

    更新日期:2008-12-01 00:00:00

  • Clinical investigation of gustatory and neurosensory alterations following mandibular third molar surgery: an observational prospective study.

    abstract:OBJECTIVE:This study aimed to prospectively observe gustatory and neurosensory alterations following surgical removal of mandibular third molars. MATERIAL AND METHODS:A prospective clinical study was conducted with patients who required mandibular third molar extraction, recruited from the Division of Oral and Maxillo...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Albuquerque AFM,Soares ECS,de Barros Silva PG,de Lima BB,Carvalho FSR,Ribeiro TR,de Sá Cavalcante D,Costa FWG

    更新日期:2019-07-01 00:00:00

  • Azithromycin suppresses P. gingivalis LPS-induced pro-inflammatory cytokine and chemokine production by human gingival fibroblasts in vitro.

    abstract:OBJECTIVE:Azithromycin is a macrolide antibiotic that appears to have both antibacterial and anti-inflammatory properties. This study aimed to investigate the effect of azithromycin on the production of pro-inflammatory cytokines and chemokines by human gingival fibroblasts (HGF) in vitro. MATERIALS AND METHODS:The ef...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Doyle CJ,Fitzsimmons TR,Marchant C,Dharmapatni AA,Hirsch R,Bartold PM

    更新日期:2015-03-01 00:00:00

  • Position of lower wisdom teeth and their relation to the alveolar nerve in orthodontic patients treated with and without extraction of premolars: a longitudinal study.

    abstract:OBJECTIVES:The present longitudinal study aimed to compare changes in the lower third molar position and nerve involvement in orthodontically treated patients with and without premolar extractions. MATERIALS AND METHODS:The sample consisted of pretreatment and posttreatment panoramic radiographs of 349 orthodontically...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Miclotte A,Van Hevele J,Roels A,Elaut J,Willems G,Politis C,Jacobs R

    更新日期:2014-09-01 00:00:00

  • Efficacy of fluoride varnish for preventing white spot lesions and gingivitis during orthodontic treatment with fixed appliances-a prospective randomized controlled trial.

    abstract:OBJECTIVES:The development of white spot lesions around orthodontic brackets and gingivitis is a common problem during orthodontic treatment with fixed appliances. This prospective randomized double-blind controlled clinical trial investigated the preventive efficacy of a one-time application of two commonly used fluor...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,随机对照试验


    authors: Kirschneck C,Christl JJ,Reicheneder C,Proff P

    更新日期:2016-12-01 00:00:00

  • Locking versus nonlocking plates in mandibular reconstruction with fibular graft--a biomechanical ex vivo study.

    abstract:OBJECTIVES:The main goal of the present study was to compare the biomechanical stability of locking plates and conventional miniplate combinations in human mandibles reconstructed with fibular grafts. MATERIALS AND METHODS:A specially developed and well-proven testing device reproduced the in vivo loading conditions o...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Trainotti S,Raith S,Kesting M,Eichhorn S,Bauer F,Kolk A,Lethaus B,Hölzle F,Steiner T

    更新日期:2014-05-01 00:00:00

  • Multibracket appliance: impression defaults and their reduction by blocking-out  -  a three-dimensional study.

    abstract:OBJECTIVES:This study examines accuracy of dental impressions and following plaster models taken during treatment with fixed appliances. MATERIALS AND METHODS:A maxillary typodont was provided with brackets. Three examiners took impressions three times each of the variants: brackets only, archwire fixed by alastics, l...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Wriedt S,Foersch M,Muhle JD,Schmidtmann I,Wehrbein H

    更新日期:2016-03-01 00:00:00

  • A new method for chlorhexidine (CHX) determination: CHX release after application of differently concentrated CHX-containing preparations on artificial fissures.

    abstract::Aims of the study were (1) to establish a method for quantification of chlorhexidine (CHX) in small volumes and (2) to determine CHX release from differently concentrated CHX-containing preparations, varnishes, and a CHX gel applied on artificial fissures. CHX determination was conducted in a microplate reader using p...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Attin T,Abouassi T,Becker K,Wiegand A,Roos M,Attin R

    更新日期:2008-09-01 00:00:00

  • Re: Does smoking habit increase the micronuclei frequency in the oral mucosa of adults compared to non-smokers? A systematic review and meta-analysis. de Geus et al., Clin Oral Investig. 2018 Jan; 22(1):81-91.

    abstract:: ...

    journal_title:Clinical oral investigations

    pub_type: 评论,信件


    authors: Nersesyan A

    更新日期:2019-01-01 00:00:00

  • Biochemical analysis of the articular disc of the temporomandibular joint with magnetic resonance T2 mapping: a feasibility study.

    abstract:OBJECTIVES:Symptoms of temporomandibular joint (TMJ) dysfunction can seriously compromise patients' quality of life. The aim of our study was to use magnetic resonance imaging (MRI) T2 mapping of the articular disc to determine whether T2 mapping of the TMJ disc is feasible in routine clinical imaging and to assess the...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Schmid-Schwap M,Bristela M,Pittschieler E,Skolka A,Szomolanyi P,Weber M,Piehslinger E,Trattnig S

    更新日期:2014-09-01 00:00:00

  • Effect of mold type, diameter, and uncured composite removal method on depth of cure.

    abstract:OBJECTIVE:This study compared the effects of mold material and diameter on the thickness of cured composite remnants and depth of cure (DOC) of resin-based composites (RBC). MATERIAL AND METHODS:One Polywave® curing light was used to photo-cure two shades of the same "bulk-fill" RBC in 4, 6, or 10-mm internal diameter...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Price RB,Rueggeberg FA,Harlow J,Sullivan B

    更新日期:2016-09-01 00:00:00

  • A retrospective cohort study of how alveolar ridge preservation affects the need of alveolar ridge augmentation at posterior tooth implant sites.

    abstract:OBJECTIVES:The aim of this study was to assess whether alveolar ridge preservation (ARP) can reduce the need of ridge augmentation at posterior tooth sites. MATERIAL AND METHODS:This study enrolled patients who received dental implants at posterior tooth sites during 2013-2019. Demographic data and dental treatment hi...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Hu KF,Lin YC,Huang YT,Chou YH

    更新日期:2021-01-11 00:00:00

  • A phase IIa randomized controlled pilot study evaluating the safety and clinical outcomes following the use of rhGDF-5/β-TCP in regenerative periodontal therapy.

    abstract::To present the safety profile, the early healing phase and the clinical outcomes at 24 weeks following treatment of human intrabony defects with open flap debridement (OFD) alone or with OFD and rhGDF-5 adsorbed onto a particulate β-tricalcium phosphate (β-TCP) carrier. Twenty chronic periodontitis patients, each with...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,随机对照试验


    authors: Windisch P,Stavropoulos A,Molnár B,Szendröi-Kiss D,Szilágyi E,Rosta P,Horváth A,Capsius B,Wikesjö UM,Sculean A

    更新日期:2012-08-01 00:00:00

  • Detection of non-cavitated approximal caries lesions in digital images from seven solid-state receptors with particular focus on task-specific enhancement filters. An ex vivo study in human teeth.

    abstract::The aim of this study was to compare detection of non-cavitated approximal caries lesions in images from seven solid-state intraoral digital receptors, with particular focus on two task-specific enhancement filters. One hundred and sixty approximal non-cavitated surfaces were radiographed under standardized conditions...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Haiter-Neto F,dos Anjos Pontual A,Frydenberg M,Wenzel A

    更新日期:2008-09-01 00:00:00

  • Three-unit CAD/CAM-generated lithium disilicate FDPs after a mean observation time of 46 months.

    abstract:OBJECTIVES:Lithium disilicate can easily be machined by CAM techniques in its metasilicate status. Due to slightly inferior material properties, the material is not yet recommended for three-unit fixed dental prosthesis (FDP) as it is the case for the press material up to the second bicuspid. Therefore, the aim of this...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Reich S,Endres L,Weber C,Wiedhahn K,Neumann P,Schneider O,Rafai N,Wolfart S

    更新日期:2014-12-01 00:00:00

  • Methodological considerations concerning the development of oral dental erosion indexes: literature survey, validity and reliability.

    abstract::Within the context of preventing non-communicable diseases, the World Health Report (2002) and the WHO Global Oral Health Program (2003) put forward a new strategy of disease prevention and health promotion. Greater emphasis is placed on developing global policies in oral health promotion and oral disease prevention. ...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,评审


    authors: Berg-Beckhoff G,Kutschmann M,Bardehle D

    更新日期:2008-03-01 00:00:00

  • Smoking affects quality of life in patients with oral squamous cell carcinomas.

    abstract::Smoking is a causative factor in oral squamous cell carcinomas (SCC). Unfortunately, only poor data exist regarding the quality of life of smokers vs non-smokers with SCC. The purpose of this study is to show a correlation between variables for comprehensive interdisciplinary rehabilitation and better patient quality ...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章,多中心研究


    authors: Krüskemper G,Handschel J

    更新日期:2012-10-01 00:00:00

  • Treatment and standard evaluation using the Peer Assessment Rating Index.

    abstract::The aim of this retrospective study was to determine the outcome of orthodontic treatment carried out on patients by postgraduate students at the Katholieke Universiteit Leuven, Belgium. The treatment outcome of 292 'final examination' patients and of 287 'control' patients was compared by means of the Peer Assessment...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Willems G,Heidbüchel R,Verdonck A,Carels C

    更新日期:2001-03-01 00:00:00

  • Tooth-implant-supported posterior fixed dental prostheses with zirconia frameworks: 3-year clinical result.

    abstract:OBJECTIVES:This case series compared the clinical survival of tooth-implant-supported (TI-S) and tooth-supported (T-S) three-unit fixed dental prostheses (FDPs) with zirconia frameworks and described the incidence of biological and technical complications. MATERIALS AND METHODS:Forty-four patients received 27 TI-S FDP...

    journal_title:Clinical oral investigations

    pub_type: 杂志文章


    authors: Beuer F,Sachs C,Groesser J,Gueth JF,Stimmelmayr M

    更新日期:2016-06-01 00:00:00