Abstract:
OBJECTIVE:The aim of this in vitro study is to evaluate the effects of resveratrol (RES) addition on the cytotoxicity and microtensile bond strength (μTBS) of different adhesives. MATERIALS AND METHODS:Five self-etching adhesives (G-aenial Bond-GC, Optibond All in One-Kerr, Gluma Self Etch-Kulzer, Clearfil S3 Bond-Kuraray, and Nova Compo-B Plus-Imicryl) were tested. They were applied to L-929 cell culture by the extract method. In the test groups, 0.5 μM RES (Sigma-Aldrich) was added into the medium. Cell viability was assessed by MTT assay after 24 h. Human extracted third molars were used for μTBS test (n = 7). The adhesives with or without 0.5 μM RES addition were applied on dentin surfaces. A composite build-up was constructed. Then, the specimens were sectioned into multiple beams with the non-trimming version of the microtensile test and subjected to microtensile forces. Statistical analysis was performed using ANOVA and post hoc Tukey test (p ˂ 0.05). RESULTS:The extracts of all adhesives decreased the cell viability. However, RES addition increased the cell viability in all groups (p ˂ 0.05). RES addition did not cause any decrease in μTBS values of the adhesives compared to baseline. Optibond All in One showed the highest μTBS after RES addition. It was followed by Clerafil S3 Bond and Nova Compo-B Plus. No difference was determined between the Optibond All in One and Clearfil S3 Bond. There was difference between Optibond All in One and Nova Compo-B Plus (p ˂ 0.05). CONCLUSION:RES addition may improve the biocompatibility without causing negative influence on μTBS of the adhesives. CLINICAL RELEVANCE:RES addition has clinical applicable potential to overcome the adverse biocompatibility of adhesives.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Atalayin C,Tezel H,Ergucu Z,Unlu N,Armagan G,Dagci T,Kose Tdoi
10.1007/s00784-018-2745-ysubject
Has Abstractpub_date
2019-08-01 00:00:00pages
3213-3218issue
8eissn
1432-6981issn
1436-3771pii
10.1007/s00784-018-2745-yjournal_volume
23pub_type
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0582-3
更新日期:2012-04-01 00:00:00
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journal_title:Clinical oral investigations
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更新日期:2018-01-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2723-4
更新日期:2019-07-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
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journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s007840050049
更新日期:1998-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00784-020-03493-0
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03413-2
更新日期:2020-08-01 00:00:00
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journal_title:Clinical oral investigations
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journal_title:Clinical oral investigations
pub_type: 杂志文章
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更新日期:2019-11-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1497-1
更新日期:2016-01-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,meta分析
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更新日期:2021-02-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2013-01-01 00:00:00
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更新日期:2015-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2013-09-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03708-4
更新日期:2021-01-06 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03091-9
更新日期:2020-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-09-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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更新日期:2019-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00784-015-1566-5
更新日期:2016-05-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
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更新日期:2021-01-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2015-12-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02905-0
更新日期:2019-12-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2749-7
更新日期:2019-08-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
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更新日期:2017-06-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1672-4
更新日期:2016-09-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-010-0485-8
更新日期:2012-02-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
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更新日期:2019-10-01 00:00:00