当前位置： SCI文献检索 > Clinical Oral Investigations期刊下所有文献 > Administration of systemic antibiotics during non-surgical periodontal therapy-a consensus report.

Administration of systemic antibiotics during non-surgical periodontal therapy-a consensus report.

Abstract：

AIM:The aim of this meta-review was to evaluate whether there is a meaningful clinical benefit regarding the use of systemic adjunctive antibiotics in the treatment of patients with periodontitis. Additionally, a consensus regarding possible recommendations for future administration of antibiotics should be reached. METHODS:A structured literature search was performed by two independent investigators focusing on systematic reviews (SR) covering adjunctive systemic antibiosis during non-surgical periodontal therapy. Additionally, recent randomized clinical trials (RCT, July 2015 to July 2017) were searched systematically to update the latest SR. Results were summarized and discussed in a plenary to reach a consensus. RESULTS:Mostly, systematic reviews and RCTs showed a significant positive effect of adjunctive systematic antibiosis compared to controls. These positive effects gain clinical relevance in patients with severe periodontal disease aged 55 years and younger. CONCLUSION:Systemic antibiotics as an adjunct to non-surgical periodontal therapy should be sensibly administered and restrictively used. Only certain groups of periodontitis patients show a significant and clinically relevant benefit after intake of systemic antibiosis during periodontal therapy. CLINICAL RELEVANCE:Avoiding antibiotic resistance and possible side effects on the human microbiome should be a focus of dentists and physicians. Thus, a sensible administration of antibiotics is mandatory. This manuscript suggests guidelines for a reasonable use.

journal_name

Clin Oral Investig

journal_title

Clinical oral investigations

authors

Pretzl B,Sälzer S,Ehmke B,Schlagenhauf U,Dannewitz B,Dommisch H,Eickholz P,Jockel-Schneider Y

doi

10.1007/s00784-018-2727-0

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

3073-3085

issue

7

eissn

1432-6981

issn

1436-3771

pii

10.1007/s00784-018-2727-0

journal_volume

23

pub_type

杂志文章,评审

相关文献

Clinical Oral Investigations文献大全
  • Influence of attachment design and material on the retention of resin-bonded attachments.

    abstract：OBJECTIVES:The purpose of this laboratory study was to evaluate the influence of the attachment design and material on the retention of resin-bonded attachments (RBAs) before and after dynamic loading. MATERIALS AND METHODS:Forty-eight caries-free human premolars were prepared for RBAs fabricated either from a CoCr al...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-018-2544-5

    authors： Jagodin S,Sasse M,Freitag-Wolf S,Kern M

    更新日期：2019-03-01 00:00:00

  • A new method for chlorhexidine (CHX) determination: CHX release after application of differently concentrated CHX-containing preparations on artificial fissures.

    abstract：:Aims of the study were (1) to establish a method for quantification of chlorhexidine (CHX) in small volumes and (2) to determine CHX release from differently concentrated CHX-containing preparations, varnishes, and a CHX gel applied on artificial fissures. CHX determination was conducted in a microplate reader using p...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-007-0166-4

    authors： Attin T,Abouassi T,Becker K,Wiegand A,Roos M,Attin R

    更新日期：2008-09-01 00:00:00

  • Polymerization pattern characterization within a resin-based composite cured using different curing units at two distances.

    abstract：OBJECTIVES:To investigate the relationship of the irradiance-beam-profile areas from six different light-curing units (LCUs) with the degree of conversion (DC), microhardness (KH), and cross-link density (CLD) throughout a resin-based composite (RBC) cured at two clinically relevant distances, and to explore the correl...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-019-02831-1

    authors： Al-Zain AO,Eckert GJ,Lukic H,Megremis S,Platt JA

    更新日期：2019-11-01 00:00:00

  • Effect of fracture orientation on detection accuracy of vertical root fractures in non-endodontically treated teeth using cone beam computed tomography.

    abstract：OBJECTIVES:This study aimed to investigate the effect of fracture orientation on the detection accuracy of vertical root fractures (VRFs) in non-endodontically treated teeth using four different cone beam computed tomography (CBCT) units. MATERIALS AND METHODS:Thirty eight out of 148 extracted human permanent teeth we...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-019-02905-0

    authors： Guo XL,Li G,Yin S,Ma RH,Guo YJ,Bornstein MM

    更新日期：2019-12-01 00:00:00

  • Is the oral cavity relevant in SARS-CoV-2 pandemic?

    abstract：OBJECTIVES:Recent scientific evidences suggest a relevant role of the oral cavity in the transmission and pathogenicity of SARS-CoV-2. METHODS:A literature search was performed in PubMed, up to April 30, 2020, focusing on SARS-CoV-2, COVID-19, oral cavity, and antimicrobial agents. RESULTS:Oral viral load of SARS-CoV...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-020-03413-2

    authors： Herrera D,Serrano J,Roldán S,Sanz M

    更新日期：2020-08-01 00:00:00

  • Analysis of the association of TNF-α, IL-1A, and IL-1B polymorphisms with peri-implantitis in a Chinese non-smoking population.

    abstract：OBJECTIVES:The purpose of this study was to investigate whether the genetic variations which could regulate inflammatory responses were associated with the risk of peri-implantitis. MATERIALS AND METHODS:We evaluated three genetic variants including tumor necrosis factor-alpha (TNF-α) - 308G/A, interleukin-1 alpha (IL...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-019-02968-z

    authors： He K,Jian F,He T,Tang H,Huang B,Wei N

    更新日期：2020-02-01 00:00:00

  • Patient-, tooth-, and dentist-related factors influencing long-term tooth retention after resective therapy in an academic setting-a retrospective study.

    abstract：OBJECTIVES:The aim of this study was to evaluate long-term (≥5 years) tooth survival after resective therapy of multi-rooted, periodontally treated teeth and investigate the influence of patient-, tooth-, and dentist-related risk factors on tooth loss. MATERIALS AND METHODS:A total of 128 patients with root-resected m...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-019-03091-9

    authors： El Sayed N,Cosgarea R,Rahim S,Giess N,Krisam J,Kim TS

    更新日期：2020-07-01 00:00:00

  • GTR treatment of intrabony defects with PLA/PGA copolymer or collagen bioresorbable membranes in combination with deproteinized bovine bone (Bio-Oss).

    abstract：:The objectives of this study were to evaluate the results of guided tissue regeneration (GTR) treatment of intrabony defects with two kinds of bioresorbable membranes, with deproteinized bovine bone (Bio-Oss) used as an adjunct. Twenty-eight patients with at least one intrabony defect with a probing pocket depth (PPD)...

    journal_title：Clinical oral investigations

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/s00784-004-0277-0

    authors： Stavropoulos A,Sculean A,Karring T

    更新日期：2004-12-01 00:00:00

  • Changes in periapical status, quality of root fillings and estimated endodontic treatment need in a similar urban German population 20 years later.

    abstract：OBJECTIVES:The study aimed at assessing, as primary objective, the periapical status and quality of root fillings, and, as secondary objective, the endodontic treatment need of a German urban population in a cross-sectional study 20 years after the first one. MATERIALS AND METHODS:Clinical and radiographic data of 353...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-018-2566-z

    authors： Connert T,Truckenmüller M,ElAyouti A,Eggmann F,Krastl G,Löst C,Weiger R

    更新日期：2019-03-01 00:00:00

  • Change in diet and oral hygiene over an 8-week period: effects on oral health and oral biofilm.

    abstract：:The aim of the study was to monitor changes in oral health and oral biofilm composition in vivo during an experiment simulating prehistoric lifestyle and diet and poor oral hygiene. Thirteen subjects lived for a period of 8 weeks under Neolithic conditions. The following clinical parameters were recorded before and af...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-009-0318-9

    authors： Al-Ahmad A,Roth D,Wolkewitz M,Wiedmann-Al-Ahmad M,Follo M,Ratka-Krüger P,Deimling D,Hellwig E,Hannig C

    更新日期：2010-08-01 00:00:00

  • Prognostic factors in direct pulp capping with mineral trioxide aggregate or calcium hydroxide: 2- to 6-year follow-up.

    abstract：OBJECTIVES:The aim of this retrospective study was to evaluate the influence of various predictors on healing outcomes after direct pulp capping (DPC) using either mineral trioxide aggregate (MTA) or calcium hydroxide (CH) as a pulp-dressing agent. MATERIALS AND METHODS:The present study included 172 mature asymptomat...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-016-1798-z

    authors： Çalışkan MK,Güneri P

    更新日期：2017-01-01 00:00:00

  • Socio-economic differences in patterns of health and oral health behaviour in 25 year old Norwegians.

    abstract：:The purpose of this study was to test the hypothesis of multidimensionality of oral and general health behaviour. To evaluate the proposed behavioural dimensions, relationships with individual beliefs and socio-economic factors were explored. A simple random sample of 1190 residents born in 1972 was drawn from the pop...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s007840000102

    authors： Astrøm AN,Rise J

    更新日期：2001-06-01 00:00:00

  • The improvement of biocompatibility of adhesives : The effects of resveratrol on biocompatibility and dentin micro-tensile bond strengths of self-etch adhesives.

    abstract：OBJECTIVE:The aim of this in vitro study is to evaluate the effects of resveratrol (RES) addition on the cytotoxicity and microtensile bond strength (μTBS) of different adhesives. MATERIALS AND METHODS:Five self-etching adhesives (G-aenial Bond-GC, Optibond All in One-Kerr, Gluma Self Etch-Kulzer, Clearfil S3 Bond-Kur...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-018-2745-y

    authors： Atalayin C,Tezel H,Ergucu Z,Unlu N,Armagan G,Dagci T,Kose T

    更新日期：2019-08-01 00:00:00

  • Mechanical sensitivity and psychological factors in patients with burning mouth syndrome.

    abstract：OBJECTIVES:The aim of this study was to compare mechanical sensitivity on the tongue using quantitative sensory testing (QST) and psychological factors using the General Health Questionnaire (GHQ) between burning mouth syndrome (BMS) patients and healthy participants. MATERIALS AND METHODS:Participants comprised 20 fe...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-018-2488-9

    authors： Honda M,Iida T,Kamiyama H,Masuda M,Kawara M,Svensson P,Komiyama O

    更新日期：2019-02-01 00:00:00

  • Functional characterization of the parathyroid hormone 1 receptor in human periodontal ligament cells.

    abstract：OBJECTIVES:Intermittent parathyroid hormone (PTH) exerts anabolic effects on bone and has been approved for osteoporosis therapy. The dual actions of PTH are mediated primarily through the parathyroid hormone 1 receptor (PTH1R). Upon ligand binding, PTH1R activates diverse signaling pathways, including cAMP/protein kin...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-013-0985-4

    authors： Abuduwali N,Lossdörfer S,Winter J,Kraus D,Guhlke S,Wolf M,Jäger A

    更新日期：2014-01-01 00:00:00

  • Efficacy and safety of selective COX-2 inhibitors for pain management after third molar removal: a meta-analysis of randomized clinical trials.

    abstract：OBJECTIVES:To compare selective COX-2 inhibitors with ibuprofen in terms of analgesia, rescue medication consumption, and adverse effects after impacted third molar removal. MATERIALS AND METHODS:Electronic databases were searched. Single dose, double-blind, randomized, and controlled clinical trials comparing the ana...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章,meta分析

    doi：10.1007/s00784-019-02910-3

    authors： González-Barnadas A,Camps-Font O,Martín-Fatás P,Figueiredo R,Gay-Escoda C,Valmaseda-Castellón E

    更新日期：2020-01-01 00:00:00

  • Isolation and characterization of SSEA-4-positive subpopulation of human deciduous dental pulp cells.

    abstract：OBJECTIVES:It is well accepted that stage-specific embryonic antigen (SSEA)-4 is an antigen that is useful to isolate adult stem cells analogous to embryonic stem cells. Therefore, in the present study, we investigated whether SSEA-4 can also be used as a marker to identify human deciduous dental pulp (D-DP) stem cells...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-014-1260-z

    authors： Kawanabe N,Fukushima H,Ishihara Y,Yanagita T,Kurosaka H,Yamashiro T

    更新日期：2015-03-01 00:00:00

  • Long-term effect of periodontal surgery on oral health and metabolic control of diabetics.

    abstract：OBJECTIVE:The objective of this study was to evaluate impact of periodontal surgery on periodontal health and on glycaemia control of type 1 and type 2 (T1DM; T2DM) diabetics with severe periodontitis, during 12 months follow-up, in comparison with non-diabetic controls. MATERIALS AND METHODS:A total of 23 T1DM and 10...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-016-1819-y

    authors： Pranckeviciene A,Siudikiene J,Ostrauskas R,Machiulskiene V

    更新日期：2017-04-01 00:00:00

  • Bleaching effect of activation of hydrogen peroxide using photon-initiated photoacoustic streaming technique.

    abstract：OBJECTIVES:This study aims to investigate the bleaching effectiveness of photon-initiated photoacoustic streaming (PIPS) using 35 % hydrogen peroxide on discolored teeth as compared with different devital bleaching techniques. MATERIALS AND METHODS:Fifty extracted human mandibular incisors were collected and artificia...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-014-1255-9

    authors： Arslan H,Akcay M,Yasa B,Hatirli H,Saygili G

    更新日期：2015-03-01 00:00:00

  • Effects of cachaça, a typical Brazilian alcoholic beverage, on submandibular glands of rats: a histomorphometric and biochemical study.

    abstract：OBJECTIVE:This study aimed to evaluate the effects of chronic consumption of cachaça, a Brazilian beverage containing alcohol, on submandibular glands (SM) of rats by using histomorphometric and biochemical parameters. MATERIALS AND METHODS:Twenty-four male rats (40 days of age) were assigned into the following four g...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-020-03290-9

    authors： Dal Prá KJ,de Fatima Moraes da Silva A,Chaves-Neto AH,Soubhia AMP

    更新日期：2020-12-01 00:00:00

  • Influence of the internal anatomy on the leakage of root canals filled with thermoplastic technique.

    abstract：OBJECTIVES:The aim of this paper is to evaluate the influence of the internal anatomy on the leakage of root canals filled with the thermoplastic technique. MATERIALS AND METHODS:The upper central incisors (UCI) and mesial roots of the lower molars (MRLM) (n = 12 each) were tested regarding leakage using the gas-enhan...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-017-2235-7

    authors： Al-Jadaa A,Attin T,Peltomäki T,Heumann C,Schmidlin PR,Paquè F

    更新日期：2018-04-01 00:00:00

  • Influence of two different cement space settings and three different cement types on the fit of polymer-infiltrated ceramic network material crowns manufactured using a complete digital workflow.

    abstract：OBJECTIVES:The study evaluates the influence of two spacer settings and three resin luting materials on the marginal and internal fit of polymer-infiltrated ceramic network (PICN) material crowns manufactured using a complete digital workflow. METHODS:Optical impressions of fifty identical dies were performed using th...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-019-03053-1

    authors： Dauti R,Lilaj B,Heimel P,Moritz A,Schedle A,Cvikl B

    更新日期：2020-06-01 00:00:00

  • Radiographic evaluation of the chronological development of permanent dentition in children infected with HIV.

    abstract：:The objective of this study is to determine if there is an association between HIV infection in children and alterations in the chronological development of permanent dentition detectable by radiographic examination. The sample comprised two groups of children: (1) 50 children infected with HIV by vertical transmissio...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-007-0124-1

    authors： Fernandes A,Cherubini K,Veeck EB,Grando LJ,Silva CL

    更新日期：2007-12-01 00:00:00

  • Evaluation of the bone regeneration potential of bioactive glass in implant site development surgeries: a systematic review of the literature.

    abstract：OBJECTIVES:The aim of this systematic review was to assess the efficacy of bioactive glass (BG) in bone regeneration for implant site development procedures. MATERIAL AND METHODS:The following specific question was formulated with reference to Population, Intervention, Control, Outcomes (PICO): "In persons that underg...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章,评审

    doi：10.1007/s00784-014-1376-1

    authors： Ioannou AL,Kotsakis GA,Kumar T,Hinrichs JE,Romanos G

    更新日期：2015-03-01 00:00:00

  • 3D accuracy of implant positions in template-guided implant placement as a function of the remaining teeth and the surgical procedure: a retrospective study.

    abstract：OBJECTIVE:The aim of this study was to investigate differences between the virtually planned and clinically achieved implant positions in completely template-guided implantations as a function of the type of edentulous space, the residual natural dentition, and the surgical implementation. MATERIALS AND METHODS:Fifty-...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-018-2339-8

    authors： Schnutenhaus S,Edelmann C,Rudolph H,Dreyhaupt J,Luthardt RG

    更新日期：2018-07-01 00:00:00

  • Quaternary ammonium compound as antimicrobial agent in resin-based sealants.

    abstract：OBJECTIVES:The aim of this study was to evaluate the influence of [2-(methacryloyloxy)ethyl] trimethylammonium chloride (METAC) in the physico-chemical properties, antibacterial activity and cytotoxicity of an experimental resin-based sealant. MATERIALS AND METHODS:An experimental resin-based sealant was formulated wi...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-019-02971-4

    authors： Garcia IM,Rodrigues SB,de Souza Balbinot G,Visioli F,Leitune VCB,Collares FM

    更新日期：2020-02-01 00:00:00

  • Azithromycin suppresses P. gingivalis LPS-induced pro-inflammatory cytokine and chemokine production by human gingival fibroblasts in vitro.

    abstract：OBJECTIVE:Azithromycin is a macrolide antibiotic that appears to have both antibacterial and anti-inflammatory properties. This study aimed to investigate the effect of azithromycin on the production of pro-inflammatory cytokines and chemokines by human gingival fibroblasts (HGF) in vitro. MATERIALS AND METHODS:The ef...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-014-1249-7

    authors： Doyle CJ,Fitzsimmons TR,Marchant C,Dharmapatni AA,Hirsch R,Bartold PM

    更新日期：2015-03-01 00:00:00

  • Non-surgical periodontal treatment improves rheumatoid arthritis disease activity: a meta-analysis.

    abstract：OBJECTIVES:The aim of the meta-analysis was to clarify the efficacy of non-surgical periodontal treatment (NSPT) in improving rheumatoid arthritis (RA) disease activity. METHODS:A systematic literature search was conducted using the PubMed, Embase, and Cochrane databases up to October 2020. A total of nine studies wer...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-021-03807-w

    authors： Sun J,Zheng Y,Bian X,Ge H,Wang J,Zhang Z

    更新日期：2021-01-29 00:00:00

  • Risk of chipping or facings failure of metal ceramic fixed partial prostheses--a retrospective data record analysis.

    abstract：:This retrospective study investigated the frequency and time history of chipping or facings failure of three-unit and four-unit tooth-supported metal ceramic (MC) fixed partial prostheses (FPDs). Six hundred fifty-four MC FPDs were inserted according to a standardized treatment protocol at the Department of Prosthodon...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-011-0511-5

    authors： Behr M,Winklhofer C,Schreier M,Zeman F,Kobeck C,Bräuer I,Rosentritt M

    更新日期：2012-04-01 00:00:00

  • Temperature rise and degree of photopolymerization conversion of nanocomposites and conventional dental composites.

    abstract：:The aim of the study was to investigate the temperature rise of a nanocomposite and a conventional hybrid dental composite during photopolymerization when cured with halogen curing lamp (QHT) and light-emitting diode (LED). Temperature rise during photopolymerization of two commercially available composites (Filtek Su...

    journal_title：Clinical oral investigations

    pub_type： 杂志文章

    doi：10.1007/s00784-008-0236-2

    authors： Atai M,Motevasselian F

    更新日期：2009-09-01 00:00:00