Abstract:
:The aim of the study was to monitor changes in oral health and oral biofilm composition in vivo during an experiment simulating prehistoric lifestyle and diet and poor oral hygiene. Thirteen subjects lived for a period of 8 weeks under Neolithic conditions. The following clinical parameters were recorded before and after the project: gingival and plaque index (Löe and Silness, Acta Odontol Scand 21:533, 1963; Silness and Löe, Acta Odontol Scand 22:121-135, 1964), probing pocket depth, and bleeding upon probing. In addition, supragingival plaque samples were collected both before and after the project and were analysed quantitatively using multiplex fluorescence in situ hybridization and confocal laser scanning microscopy. The following plaque bacteria were evaluated: Streptococcus spp., Veillonella spp., Fusobacterium nucleatum, and Actinomyces naeslundii. The plaque index increased significantly from 1.12 up to 1.55 over the 8-week period (gingival index before, 0.46; after, 0.93; p < 0.05). A strong correlation of both indices was recorded before (r = 0.77) and after (r = 0.83) participation in the study. Each of the children in the study showed a progression of carious lesions and/or new areas of demineralisation. The probing pocket depth and bleeding upon probing were not affected. All subjects yielded an intra-individual shift in biofilm composition. The proportion of F. nucleatum decreased across all subjects. The proportion of Veillonella spp. increased among the children. Poor oral hygiene and change of diet lead to an increase in oral plaque and gingival inflammation. The inter-individual comparison indicated a shift in bacterial composition.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Al-Ahmad A,Roth D,Wolkewitz M,Wiedmann-Al-Ahmad M,Follo M,Ratka-Krüger P,Deimling D,Hellwig E,Hannig Cdoi
10.1007/s00784-009-0318-9subject
Has Abstractpub_date
2010-08-01 00:00:00pages
391-6issue
4eissn
1432-6981issn
1436-3771journal_volume
14pub_type
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journal_title:Clinical oral investigations
pub_type: 杂志文章
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更新日期:2014-12-01 00:00:00
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更新日期:2020-04-01 00:00:00
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更新日期:2019-03-01 00:00:00
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journal_title:Clinical oral investigations
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840050038
更新日期:1998-03-01 00:00:00
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journal_title:Clinical oral investigations
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更新日期:2016-01-01 00:00:00
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更新日期:2017-09-01 00:00:00
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journal_title:Clinical oral investigations
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更新日期:2004-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-07-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2016-12-01 00:00:00
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更新日期:2020-10-01 00:00:00
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pub_type: 评论,信件
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更新日期:2019-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2008-12-01 00:00:00
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更新日期:2016-03-01 00:00:00
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更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2016-09-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
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更新日期:2021-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-08-15 00:00:00
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pub_type: 杂志文章
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journal_title:Clinical oral investigations
pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-06-01 00:00:00