Abstract:
:The aim of the present study was to comparatively evaluate DNA damage (micronucleus) and cellular death (pyknosis, karyolysis, and karyorrhexis) in exfoliated oral mucosa cells from smokers and non-smokers submitted to dental X-ray using two anatomic sites: buccal mucosa and lateral border of the tongue. A total of 15 heavy smokers and 17 non-smokers were submitted to panoramic dental radiography for orthodontic reasons. Individuals had epithelial cells from cheek and lateral border of the tongue mechanically exfoliated, placed in fixative, and dropped in clean slides which were checked for the above nuclear phenotypes. The results pointed out no significant statistically differences (p > 0.05) of micronucleated oral mucosa cells before versus after X-ray exposure for both oral sites evaluated either to smokers or to non-smokers. X-ray exposure was able to increase other nuclear alterations closely related to cytotoxicity such as karrhyorexis, pyknosis, and karyolysis for two groups evaluated. Nevertheless, the most pronunciated effects were found to lateral border of the tongue of smokers. In summary, these data indicate that panoramic X-ray is able to induce cellular death in oral mucosa cells. It seems that lateral border of the tongue is more sensitive site to cytotoxic insult induced by ionizing radiation combined with continuous cigarette smoke exposure.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Angelieri F,de Cássia Gonçalves Moleirinho T,Carlin V,Oshima CT,Ribeiro DAdoi
10.1007/s00784-009-0345-6subject
Has Abstractpub_date
2010-12-01 00:00:00pages
669-74issue
6eissn
1432-6981issn
1436-3771journal_volume
14pub_type
杂志文章abstract::The goal of this investigation was to evaluate the effect of postoperative exposure of two different bioresorbable membranes on the guided tissue regeneration (GTR) healing results compared to nonexposed sites. In each of 25 patients one pair of contralateral intrabony lesions was treated either with polylactic acid (...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840050021
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVES:There is an increasing number of oral squamous cell carcinoma (OSCC) associated with HPV-16. However, p16 expression by immunohistochemistry as the current gold standard for a surrogate marker for virus infection reveals unsatisfying diagnostic accuracy. The aim of this study was to investigate a new rapid t...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03601-0
更新日期:2020-10-23 00:00:00
abstract:OBJECTIVES:Resin polymerisation shrinkage reduces the congruence of the denture base with denture-bearing tissues and thereby decreases the retention of conventionally fabricated dentures. CAD/CAM denture manufacturing is a subtractive process, and polymerisation shrinkage is not an issue anymore. Therefore, CAD/CAM de...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2369-2
更新日期:2018-11-01 00:00:00
abstract::The objectives of this study were to evaluate the results of guided tissue regeneration (GTR) treatment of intrabony defects with two kinds of bioresorbable membranes, with deproteinized bovine bone (Bio-Oss) used as an adjunct. Twenty-eight patients with at least one intrabony defect with a probing pocket depth (PPD)...
journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00784-004-0277-0
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVES:The main purpose of this prospective, double-blind, randomized study was to evaluate anaesthetic parameters, postoperative analgesia and vasoactive properties of levobupivacaine and bupivacaine for lower third molar surgery. MATERIAL AND METHODS:Sixty patients (ASA I) were scheduled for lower third molar su...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1114-0
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare the palatal total support tissues (TSTs) and bone support tissues (BSTs) at 5-mm paramedian section to the midsagittal suture between mouth breathers with high-narrow palates and nose breathers with normal palates and confirm the practicability and limitation on superimpo...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03004-w
更新日期:2020-03-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03686-7
更新日期:2020-11-24 00:00:00
abstract:OBJECTIVES:Targeted modifications of the bulk implant surfaces using bioactive agents provide a promising tool for improvement of the long-term bony and soft tissue integration of dental implants. In this study, we assessed the cellular responses of primary human gingival fibroblasts (HGF) to different surface modifica...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1784-5
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:To develop and evaluate predictive nomogram for extended duration of surgery in patients following mandibular third molars (M3M) removal. MATERIALS AND METHODS:A retrospectively observational study was performed and designed. A credible random split-sample method was used to divide data into training and va...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03499-8
更新日期:2020-08-10 00:00:00
abstract::At a dental office in Münster, Germany, the majority of gold inlays incorporated between July 1969 and August 1999 (n=2,071) in 531 patients were checked with reference to the dental records and assessed retrospectively to determine their longevity. One hundred seventy-five gold inlays were rated as failures (no longe...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840100119
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVES:Most patients with bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) report a previous tooth extraction at the necrosis site before the diagnosis was made. At older ages, most teeth are extracted due to periodontal disease, which is per se another BP-ONJ trigger factor. The aim of this study was t...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-0974-7
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:To assess the perception of oral health and oral care needs, barriers and current practices as perceived by managers and caregivers in organizations for people with disabilities in Flanders. MATERIALS AND METHODS:Two questionnaires were developed, one for managers and one for caregivers. The questionnaires ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03071-z
更新日期:2020-06-01 00:00:00
abstract::In the original version of this article, the following were noted for correction. ...
journal_title:Clinical oral investigations
pub_type: 已发布勘误
doi:10.1007/s00784-020-03657-y
更新日期:2020-10-26 00:00:00
abstract::The aims of the present study were: a) to assess the impact of the intraoral location on the rate of biofilm growth, and b) to establish an in vivo biofilm model to examine intraoral biofilm growth. Eight healthy volunteers wore acrylic splints with 15 glass slabs each in the upper and lower jaws to build up plaque. A...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-004-0255-6
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVES:The aim of the meta-analysis was to clarify the efficacy of non-surgical periodontal treatment (NSPT) in improving rheumatoid arthritis (RA) disease activity. METHODS:A systematic literature search was conducted using the PubMed, Embase, and Cochrane databases up to October 2020. A total of nine studies wer...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-021-03807-w
更新日期:2021-01-29 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03138-x
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the effect of daily exposure to a denture cleanser on a multispecies biofilm. MATERIALS AND METHODS:Multispecies biofilms (five bacteria and Candida albicans) were developed for 64.5 h on acrylic resin specimens and randomized into control and experimental groups. In the...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-014-1210-9
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to compare the effect of one-stage full-mouth disinfection (FMD) and conventional quadrant scaling in four weekly sessions (QS) on periodontal clinical parameters and halitosis among individuals with advanced chronic periodontitis. MATERIALS AND METHODS:In this randomized cont...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-016-1959-0
更新日期:2017-06-01 00:00:00
abstract::The aim of this retrospective study was to determine the outcome of orthodontic treatment carried out on patients by postgraduate students at the Katholieke Universiteit Leuven, Belgium. The treatment outcome of 292 'final examination' patients and of 287 'control' patients was compared by means of the Peer Assessment...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840000094
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:Interleukin 8 (IL-8) is a pro-angiogenic, pro-inflammatory mediator that belongs to the family of chemokines. Due to its pro-angiogenic characteristic, it may play a vital role in tumour angiogenesis and progression. OBJECTIVES:This study was designed to estimate the levels of salivary IL-8 in oral precance...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0723-3
更新日期:2013-03-01 00:00:00
abstract::The alveolar cleft in patients with clefts of lip, alveolus and palate (CLAP) is usually reconstructed with an autologous bone graft. Harvesting of autologous bone grafts is associated with more or less donor site morbidity. Donor site morbidity could be eliminated if bone is fabricated by growth factor-aided tissue e...
journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s00784-011-0547-6
更新日期:2011-06-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03528-6
更新日期:2020-09-01 00:00:00
abstract:: ...
journal_title:Clinical oral investigations
pub_type: 信件
doi:10.1007/s00784-018-2619-3
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:Azithromycin is a macrolide antibiotic that appears to have both antibacterial and anti-inflammatory properties. This study aimed to investigate the effect of azithromycin on the production of pro-inflammatory cytokines and chemokines by human gingival fibroblasts (HGF) in vitro. MATERIALS AND METHODS:The ef...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1249-7
更新日期:2015-03-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2194-z
更新日期:2018-03-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03177-4
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVES:This study aimed to evaluate and correlate the efficacy and cytotoxicity of a 35 % hydrogen peroxide (HP) bleaching gel after different application times on dental enamel. MATERIALS AND METHODS:Enamel/dentin disks in artificial pulp chambers were placed in wells containing culture medium. The following grou...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0883-1
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate long-term (≥5 years) tooth survival after resective therapy of multi-rooted, periodontally treated teeth and investigate the influence of patient-, tooth-, and dentist-related risk factors on tooth loss. MATERIALS AND METHODS:A total of 128 patients with root-resected m...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03091-9
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVES:Investigate the biochemistry of in vivo healthy oral tissues through Raman spectroscopy. We aimed to characterize the biochemical features of healthy condition in oral subsites (buccal mucosa, lip, tongue, and gingiva) of healthy subjects. More specifically, we investigated Raman spectral characteristics and...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2714-5
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVES:This case series compared the clinical survival of tooth-implant-supported (TI-S) and tooth-supported (T-S) three-unit fixed dental prostheses (FDPs) with zirconia frameworks and described the incidence of biological and technical complications. MATERIALS AND METHODS:Forty-four patients received 27 TI-S FDP...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1594-1
更新日期:2016-06-01 00:00:00