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Getting a "Hold" on NPC2.

Abstract：

:Lipoprotein cholesterol is mobilized from lysosomes by actions of the NPC1 and NPC2 proteins. In this issue of Cell Metabolism, Harrison et al. report on identification of an NPC2-interacting protein, the Nogo-B receptor, that regulates NPC2 protein levels. NPC2 stabilization may represent a novel mechanism through which cells respond to endocytosed cholesterol.

journal_name

Cell Metab

journal_title

Cell metabolism

authors

Ory DS

doi

10.1016/j.cmet.2009.08.006

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

161-2

issue

3

eissn

1550-4131

issn

1932-7420

pii

S1550-4131(09)00235-6

journal_volume

10

pub_type

评论,杂志文章

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