Abstract:
:In 584 consecutive patients with no previous history of cancer or polypectomy, 769 adenomas were excised endoscopically and classified retrospectively according to the following parameters: macroscopic growth pattern, size, histological type, grade of dysplasia, anatomical site, presence of adenocarcinoma (ADK), number of adenomas and sex and age of the patient. A multivariate logistic analysis confirmed that size and histological type are the 2 most important predictors of ADK, both in solitary and in multiple adenomas. Adenomas located in the sigmoid portion and in the rectum have an increased probability of ADK, independent of size and histology. Multiple polyps, when compared to solitary polyps, were more frequent in males (p less than 0.01) and were more often larger than 2 cm. Significant similarities in histology, morphology and degree of dysplasia were observed among multiple adenomas from the same patient.
journal_name
Int J Cancerjournal_title
International journal of cancerauthors
Gatteschi B,Costantini M,Bruzzi P,Merlo F,Torcoli R,Nicolo Gdoi
10.1002/ijc.2910490406subject
Has Abstractpub_date
1991-10-21 00:00:00pages
509-12issue
4eissn
0020-7136issn
1097-0215journal_volume
49pub_type
杂志文章abstract::Although a screening program for gastric cancer, using barium X-ray examination, has been carried out widely in Japan for the past 3 decades, there is insufficient evidence to confirm its effectiveness in terms of reducing mortality. To evaluate the effectiveness of the screening, a population-based case-control study...
journal_title:International journal of cancer
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更新日期:2008-06-01 00:00:00
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