Comparison of assay methods for detection of circulating tumor cells in metastatic breast cancer: AdnaGen AdnaTest BreastCancer Select/Detect™ versus Veridex CellSearch™ system.

abstract：:Serum vitamin D3-binding protein (Gc protein) is the precursor for the principal macrophage activating factor (MAF). The MAF precursor activity of serum Gc protein of breast cancer patients was lost or reduced because Gc protein was deglycosylated by serum alpha-N-acetylgalactosaminidase (Nagalase) secreted from cance...

journal_title：International journal of cancer

authors： Yamamoto N,Suyama H,Yamamoto N,Ushijima N

更新日期：2008-01-15 00:00:00

abstract：:Sprague-Dawley rats were given combinations of aminopyrine or oxytetracycline and sodium nitrite in drinking water. Of 30 animals receiving 0.1% (1,000 ppm) of aminopyrine and sodium nitrite for 30 weeks, 29 died with hemangioendothelial sarcomas of the liver. The same tumor caused death in 26 of 30 animals that recei...

journal_title：International journal of cancer

authors： Taylor HW,Lijinsky W

更新日期：1975-08-15 00:00:00

abstract：:Many studies have focused on global hypomethylation or hypermethylation of tumor suppressor genes, but less is known about the impact of promoter hypomethylation of oncogenes. We previously showed that promoter methylation may gradually increase or decrease during the transition from gastric mucosa (GM) to intestinal ...

journal_title：International journal of cancer

authors： Seo EH,Kim HJ,Kim JH,Lim B,Park JL,Kim SY,Lee SI,Jeong HY,Song KS,Kim YS

更新日期：2020-06-15 00:00:00

abstract：:To assess the effect of different hospital types or surgical volume on the survival of ovarian cancer patients, a nationwide and population-based analysis was carried out in Finland. The study included all 3,851 ovarian cancer patients operated from 1983-94. The patients were classified according to the hospital of th...

journal_title：International journal of cancer

authors： Kumpulainen S,Grénman S,Kyyrönen P,Pukkala E,Sankila R

更新日期：2002-12-10 00:00:00

abstract：:Caspase recruitment domain-containing protein 9 (CARD9) is an adaptor protein and highly expressed in myeloid cells. Our previous study demonstrates a critical protective effect of CARD9 in the development of colitis-associated colon cancer. Nevertheless, the effect of CARD9 in lung cancer remains unclear. Here, using...

journal_title：International journal of cancer

authors： Qu J,Liu L,Xu Q,Ren J,Xu Z,Dou H,Shen S,Hou Y,Mou Y,Wang T

更新日期：2019-10-15 00:00:00

abstract：:The human MUC1 gene expresses at least 2 type 1 membrane proteins: MUC1/REP, a polymorphic high m.w. MUC1 glycoprotein often highly expressed in breast cancer tissues and containing a variable number of tandem 20 amino acid repeat units, and the MUC1/Y protein, which lacks this repeat array and, therefore, is not poly...

journal_title：International journal of cancer

authors： Baruch A,Hartmann M,Zrihan-Licht S,Greenstein S,Burstein M,Keydar I,Weiss M,Smorodinsky N,Wreschner DH

更新日期：1997-05-29 00:00:00

abstract：:High circulating glucose, insulin resistance and obesity appear to be associated with increased risk of breast cancer (BC). We sought further insight into the relation of these variables to BC. We assessed associations of BC risk with serum fasting glucose, insulin, homeostasis model assessment-insulin resistance (HOM...

journal_title：International journal of cancer

authors： Sieri S,Muti P,Claudia A,Berrino F,Pala V,Grioni S,Abagnato CA,Blandino G,Contiero P,Schunemann HJ,Krogh V

更新日期：2012-02-15 00:00:00

abstract：:The transcription factor OTX2 has been implicated as an oncogene in medulloblastoma, which is the most common malignant brain tumor in children. It is highly expressed in most medulloblastomas and amplified in a subset of them. To study the role OTX2 has in medulloblastoma we investigated the downstream pathway of OTX...

journal_title：International journal of cancer

authors： Bunt J,Hasselt NE,Zwijnenburg DA,Hamdi M,Koster J,Versteeg R,Kool M

更新日期：2012-07-15 00:00:00

abstract：:In a proportion of patients presenting mismatch repair (MMR)-deficient tumors, no germline MMR mutations are identified, the so-called Lynch-like syndrome (LLS). Recently, MMR-deficient tumors have been associated with germline mutations in POLE and MUTYH or double somatic MMR events. Our aim was to elucidate the mole...

journal_title：International journal of cancer

authors： Vargas-Parra GM,González-Acosta M,Thompson BA,Gómez C,Fernández A,Dámaso E,Pons T,Morak M,Del Valle J,Iglesias S,Velasco À,Solanes A,Sanjuan X,Padilla N,de la Cruz X,Valencia A,Holinski-Feder E,Brunet J,Feliubadaló L

更新日期：2017-10-01 00:00:00

abstract：:Cancer initiation is presumed to occur in utero for many childhood cancers and it has been hypothesized that advanced paternal age may have an impact due to the increasing number of mutations in the sperm DNA with increasing paternal age. We examined the association between paternal age and specific types of childhood...

journal_title：International journal of cancer

authors： Urhoj SK,Raaschou-Nielsen O,Hansen AV,Mortensen LH,Andersen PK,Nybo Andersen AM

更新日期：2017-06-01 00:00:00

abstract：:Survival for breast cancer (BC) is lower in eastern than northern/central Europe, and in older than younger women. We analysed how comorbidities at diagnosis affected whether selected standard treatments (STs) were given, across Europe and over time, also assessing consequences for survival/relapse. We analysed 7581 s...

journal_title：International journal of cancer

authors： Minicozzi P,Van Eycken L,Molinie F,Innos K,Guevara M,Marcos-Gragera R,Castro C,Rapiti E,Katalinic A,Torrella A,Žagar T,Bielska-Lasota M,Giorgi Rossi P,Larrañaga N,Bastos J,Sánchez MJ,Sant M,European HR Working Group on

更新日期：2019-05-01 00:00:00

abstract：:The Eph receptor A2 (EphA2) is overexpressed in a range of human epithelial cancers, a phenotype that is associated with cancer cell proliferation, progression and angiogenesis. Mouse models of mammary neoplasia have confirmed the role of EphA2 as mice carrying a knockout allele of EphA2 were resistant to breast cance...

journal_title：International journal of cancer

authors： Bogan C,Chen J,O'Sullivan MG,Cormier RT

更新日期：2009-03-15 00:00:00

abstract：:Two groups of rabbits were inoculated on the day of birth or at 4 weeks of age with a human T-cell leukemia virus type-I (HTLV-I)-infected and transformed rabbit cell line (Ra-I). Rabbits seroconverted to HTLV-I, as determined by indirect immunofluorescence, by 3 weeks after inoculation and remained persistently serop...

journal_title：International journal of cancer

authors： Cockerell GL,Lairmore M,De B,Rovnak J,Hartley TM,Miyoshi I

更新日期：1990-01-15 00:00:00

abstract：:To investigate the association between hysterectomy and thyroid cancer subtypes based on histopathology. They did a nationwide, population-based, cohort study from 1973 to 2009 in Sweden. All women above 18 years of age during the period between January 1, 1973 and December 31, 2009 from the Register of Population (n ...

journal_title：International journal of cancer

authors： Falconer H,Yin L,Bellocco R,Altman D

更新日期：2017-04-15 00:00:00

abstract：:We have examined, in proliferating neoplastic cells, the effect on DNA of EGTA (a chelator of Ca2+) and W7 (an inhibitor of calmodulin). The treatment results in release of single-stranded DNA fragments (2-10 kb) from pre-labelled HMW DNA. When DNA from synchronized neoplastic cells in S phase is examined, almost all ...

journal_title：International journal of cancer

authors： Lönn U,Lönn S

更新日期：1986-06-15 00:00:00

abstract：:Human papillomavirus (HPV) is an important factor for the development of tonsillar squamous cell carcinoma (TSCC). In addition, patients with HPV-positive TSCC have a better clinical outcome than patients with HPV-negative TSCC. Although, HPV is an important prognostic marker, additional biomarkers are needed to bette...

journal_title：International journal of cancer

authors： Näsman A,Andersson E,Nordfors C,Grün N,Johansson H,Munck-Wikland E,Massucci G,Dalianis T,Ramqvist T

更新日期：2013-01-01 00:00:00

abstract：:Leukocyte functions (superoxide production and phagocytosis) were evaluated in patients with testicular cancer who had undergone super-high-dose chemotherapy (SHDT) with peripheral blood stem cell transplantation (PBSCT). In 5 patients with advanced or relapsed testicular cancer who received 8 cycles of SHDT with PBSC...

journal_title：International journal of cancer

authors： Yamada Y,Hara I,Gohji K,Okada H,Arakawa S,Kamidono S

更新日期：1997-07-03 00:00:00

abstract：:In our study, we aimed to investigate the expression of N-cadherin and E-cadherin and their dependency on epithelial-mesenchymal transition regulators SNAI1, SIP1 and TWIST in human colon cancer. Expression of E-cadherin and N-cadherin was examined by immunohistochemistry in 80 colon carcinomas by using paraffin embed...

journal_title：International journal of cancer

authors： Rosivatz E,Becker I,Bamba M,Schott C,Diebold J,Mayr D,Höfler H,Becker KF

更新日期：2004-09-20 00:00:00

abstract：:The treatment of human peripheral blood mononuclear cells (PBMC) with micromolar concentrations of SV-IV, a major protein secreted from the rat seminal vesicle epithelium, promotes in this cell population a marked cytotoxic activity against the Raji lymphoblastoid cell line. This activity is apparently due to cell-to-...

journal_title：International journal of cancer

authors： Peluso G,Marchese M,Furgi A,Ranieri M,Russo Spena S,Ravagnan G,Fuggetta MP,Porta R,Metafora V,Metafora S

更新日期：1997-07-17 00:00:00

abstract：:DNA sequences coding for simian virus 40 (SV40) large T antigen have been detected at different frequencies in human non-Hodgkin's lymphomas (NHL) by PCR techniques as well as immunohistochemistry. A highly sensitive quantitative real-time PCR specific for a sequence of SV40 large T antigen was established to test whe...

journal_title：International journal of cancer

authors： Schüler F,Dölken SC,Hirt C,Dölken MT,Mentel R,Gürtler LG,Dölken G

更新日期：2006-01-15 00:00:00

abstract：:Recently, air pollution has been classified as a carcinogen largely on the evidence of epidemiological studies of lung cancer. However, there have been few prospective studies that have evaluated associations between fine particulate matter (PM2.5 ) and cancer at lower concentrations. We conducted a prospective analys...

journal_title：International journal of cancer

authors： Tomczak A,Miller AB,Weichenthal SA,To T,Wall C,van Donkelaar A,Martin RV,Crouse DL,Villeneuve PJ

更新日期：2016-11-01 00:00:00

abstract：:We showed earlier that interferon-gamma is a powerful inducer of differentiation of human neuroblastoma (NB) cells. Although 2',5' oligo-adenylate synthetase (2,5 OAS) may play a role in mediating the anti-proliferative and/or differentiative effects of interferons (IFNs), direct evidence is lacking. We have investiga...

journal_title：International journal of cancer

authors： Corrias MV,Gribaudo G,Guarnaccia F,Ponzoni M

更新日期：1995-07-17 00:00:00

abstract：:The amplification of the q21 band of chromosome 8 (8q21) occurs in a large percentage of breast cancers. WWP1, an HECT domain-containing ubiquitin E3 ligase located in the 8q21 region, negatively regulates the TGF-beta tumor suppressor pathway. To characterize the role of WWP1 in breast cancer, we analyzed WWP1 gene d...

journal_title：International journal of cancer

authors： Chen C,Zhou Z,Ross JS,Zhou W,Dong JT

更新日期：2007-07-01 00:00:00

abstract：:Microarray analysis of paired cultures of normal and cancerous urothelial cells revealed differences in cytokeratin and adhesion gene expression. Normal cells expressed autocrine growth factor genes more strongly whereas carcinoma cells were distinguished by concomitant expression of urothelial and epidermal different...

journal_title：International journal of cancer

authors： Dokun OY,Florl AR,Seifert HH,Wolff I,Schulz WA

更新日期：2008-12-15 00:00:00

abstract：:We studied the in vivo growth-inhibitory effect of the new S-adenosylmethionine decarboxylase inhibitor 4-amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A). L1210-bearing DBA-2 mice were treated with increasing CGP 48664A doses from 1 day after i.p. L1210 cell inoculation. Treatment was continued for 4 days, after w...

journal_title：International journal of cancer

authors： Dorhout B,Te Velde RJ,Ferwerda H,Kingma AW,De Hoog E,Muskiet FA

更新日期：1995-04-10 00:00:00

abstract：:In a series of consecutive 51chromium (51Cr) assays, 21 melanoma and 14 colo-rectal carcinoma patients were tested for their in vitro cell-mediated immune reactions to melanoma, rectal adenocarcinoma, and normal fibroblast target cells. Blood lymphocytes (BL) from four individuals were included in each experiment. In ...

journal_title：International journal of cancer

authors： Steele G Jr,Sjögren HO,Stadenberg I

更新日期：1976-01-15 00:00:00

abstract：:Chicken embryo fibroblasts and hepatocytes were studied in the presence of catalase and superoxide dismutase in order to establish whether these enzymes had the capacity to favour cell multiplication as previously shown for in vitro tumour ascites cells (ATP C+). The results indicate that, unlike ATP C+ cells, both fi...

journal_title：International journal of cancer

authors： Liotti FS,Bodo M,Menghini AR,Guerrieri P,Mariucci G,Bruschelli G

更新日期：1987-09-15 00:00:00

abstract：:Human papillomavirus (HPV) genomes usually persist as episomal molecules in HPV associated preneoplastic lesions whereas they are frequently integrated into the host cell genome in HPV-related cancers cells. This suggests that malignant conversion of HPV-infected epithelia is linked to recombination of cellular and vi...

journal_title：International journal of cancer

authors： Luft F,Klaes R,Nees M,Dürst M,Heilmann V,Melsheimer P,von Knebel Doeberitz M

更新日期：2001-04-01 00:00:00

abstract：:Heat shock protein 90 (Hsp90) is a molecular chaperone that promotes the conformational maturation of numerous client proteins, many of which play critical roles in tumor cell growth and survival. The ansamycin-based Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) is currently in Phase III clinical tes...

journal_title：International journal of cancer

authors： Yin X,Zhang H,Lundgren K,Wilson L,Burrows F,Shores CG

更新日期：2010-03-01 00:00:00

abstract：:Multiple myeloma, a neoplasm of plasma cells, accounts for approximately approximately 15% of lymphatohematopoietic cancers (LHC) and 2% of all cancers in the US. Incidence rates increase with age, particularly after age 40, and are higher in men, particularly African American men. The etiology is unknown with no esta...

journal_title：International journal of cancer

authors： Alexander DD,Mink PJ,Adami HO,Cole P,Mandel JS,Oken MM,Trichopoulos D

更新日期：2007-01-01 00:00:00