Detection of integrated papillomavirus sequences by ligation-mediated PCR (DIPS-PCR) and molecular characterization in cervical cancer cells.

abstract：:Human lymphoblastoid interferon inhibited the growth in vitro of fibroblasts and epithelial cells from normal, hyperplastic and neoplastic human breast tissue. At an interferon concentration of 10(3) inter-national units (IU) per ml, the inhibitory effects on monolayer growth were completely reversible but the growth ...

journal_title：International journal of cancer

authors： Balkwill F,Watling D,Taylor-Papadimitriou J

更新日期：1978-09-15 00:00:00

abstract：:Peptidylarginine deiminases (PADs) catalyze the conversion of arginine residues to citrulline residues on target proteins in the presence of calcium ions. This elaborate type of posttranslational modification is termed citrullination. PADs may regulate gene transcriptional activity via histone citrullination. There ha...

journal_title：International journal of cancer

authors： Wang Y,Chen R,Gan Y,Ying S

更新日期：2021-01-15 00:00:00

abstract：:Cancer-germline genes (CGGs) code for immunogenic antigens that are present on various human tumors but not on normal tissues. The importance of CGGs in cancer immunotherapy has led to detailed studies of their expression in a range of human tumors. We measured the levels of expression of 12 CGGs in various pediatric ...

journal_title：International journal of cancer

authors： Jacobs JF,Brasseur F,Hulsbergen-van de Kaa CA,van de Rakt MW,Figdor CG,Adema GJ,Hoogerbrugge PM,Coulie PG,de Vries IJ

更新日期：2007-01-01 00:00:00

abstract：:We have surveyed the incidence of adult T-cell leukemia/lymphoma (ATLL) in an endemic area of 290,464 inhabitants for 7 years. We now revise our previous results on the basis of additional findings and estimate the age- and sex-specific cumulative rate for HTLV-I carriers, the adoption of which is recommended by curre...

journal_title：International journal of cancer

authors： Kondo T,Kono H,Miyamoto N,Yoshida R,Toki H,Matsumoto I,Hara M,Inoue H,Inatsuki A,Funatsu T

更新日期：1989-06-15 00:00:00

abstract：:The APTIMA HPV Assay (AHPV) allows detection of 14 high-risk human papillomavirus (HPV) RNA types in cervical specimens. Until present, the assay has been compared to HPV DNA tests only in triage settings. Herein, we compare AHPV with a DNA assay (Hybrid Capture 2; HC2) and liquid-based cytology (LBC; using PreservCyt...

journal_title：International journal of cancer

authors： Monsonego J,Hudgens MG,Zerat L,Zerat JC,Syrjänen K,Halfon P,Ruiz F,Smith JS

更新日期：2011-08-01 00:00:00

abstract：:Lysine-specific demethylase 1 (LSD1), a histone lysine demethylase with the main specificity for H3K4me2, has been shown to be overexpressed in rhabdomyosarcoma (RMS) tumor samples. However, its role in RMS biology is not yet well understood. Here, we identified a new role of LSD1 in regulating adhesion of RMS cells. ...

journal_title：International journal of cancer

authors： Haydn T,Kehr S,Willmann D,Metzger E,Schüle R,Fulda S

更新日期：2020-06-15 00:00:00

abstract：:By transmission and scanning electron microscopic studies of MC-29 virus-infected CEC cultures, C-type virus particles were detected in the medium of infected cultures, in infected cells and in intracellular vacuoles. Virus budding was also observed. In the scanning electron microscope (SEM) so-called blebs appeared o...

journal_title：International journal of cancer

authors： Podmaniczky E,Szende B,Lapis K,Ferenc G

更新日期：1976-10-15 00:00:00

abstract：:The MYH gene has recently been shown to be associated with a recessive form of colorectal adenomatous polyposis. Two common mutations in the MYH gene have been identified that lend themselves to rapid screening. We have examined a series of 302 individuals comprising 120 control subjects, 120 patients diagnosed with a...

journal_title：International journal of cancer

authors： Kairupan CF,Meldrum CJ,Crooks R,Milward EA,Spigelman AD,Burgess B,Groombridge C,Kirk J,Tucker K,Ward R,Williams R,Scott RJ

更新日期：2005-08-10 00:00:00

abstract：:The study of the relationship between dietary intake of fatty acids and the risk of breast cancer has not yielded definite conclusions with respect to causality, possibly because of methodological issues inherent to nutritional epidemiology. To evaluate the hypothesis of possible protection of n-3 polyunsaturated fatt...

journal_title：International journal of cancer

authors： Chajès V,Hultén K,Van Kappel AL,Winkvist A,Kaaks R,Hallmans G,Lenner P,Riboli E

更新日期：1999-11-26 00:00:00

abstract：:It has been established that disturbances in intracellular signaling pathways play a considerable part in the oncologic process. Phosphatidylinositol-3-kinase (PI3K) has become of key interest in cancer therapy because of its high mutation frequency and/or gain in function of its catalytic subunits in cancer cells. We...

journal_title：International journal of cancer

authors： Gobin B,Huin MB,Lamoureux F,Ory B,Charrier C,Lanel R,Battaglia S,Redini F,Lezot F,Blanchard F,Heymann D

更新日期：2015-02-15 00:00:00

abstract：:Polyclonal and monoclonal antibodies were used to characterize human milk fat globule (HMFG) membrane antigens, using gel filtration, ion exchange chromatography and western blotting. Although originally generated against HMFG, monoclonal antibodies also reacted with skim milk. In western blotting, several antigen mol...

journal_title：International journal of cancer

authors： Ashorn P,Krohn K

更新日期：1985-02-15 00:00:00

abstract：:The distribution of aminoterminal propeptides of type-III procollagen (indicating the presence of type-III pN-collagen, i.e., type-III collagen molecule with a non-cleaved aminoterminal propeptide), laminin and type-IV collagen was studied by immunohistochemical methods. The results were compared with the distribution...

journal_title：International journal of cancer

authors： Karttunen T,Alavaikko M,Apaja-Sarkkinen M,Autio-Harmainen H

更新日期：1988-01-15 00:00:00

abstract：:Tumorigenic clonal lines derived from soft agar colonies induced by DMBA-transformed feline embryo cells were isolated and characterized. The morphologically altered clonal cells formed large aggregates, growing in this aggregate form when suspended in liquid growth medium above an agar base and forming colonies in so...

journal_title：International journal of cancer

authors： Rhim JS,Koh KS,Chen A,Essex M

更新日期：1981-07-15 00:00:00

abstract：:We have analysed expression of the first 7 members of the family of heparin-binding fibroblast growth factor (FGFs) and their 4 high-affinity receptors (FGFRs) in human pancreatic carcinoma cell lines, both at the mRNA and protein levels. In cell lines expressing FGFRs, 2 typical patterns were observed: (i) expression...

journal_title：International journal of cancer

authors： Leung HY,Gullick WJ,Lemoine NR

更新日期：1994-12-01 00:00:00

abstract：:The recently identified cell adhesion regulator (CAR) modulates the process of integrin-mediated cell adhesion. The CAR gene is located on 16q, a locus at which high levels of allelic losses have been demonstrated in advanced human hepatocellular carcinoma (HCC). We studied the possible involvement of the CAR gene in ...

journal_title：International journal of cancer

authors： Yamamoto H,Itoh F,Sakamoto H,Nakajima Y,Une Y,Hinoda Y,Imai K

更新日期：1997-06-20 00:00:00

abstract：:Human 8-oxoguanine DNA glycosylase 1 (hOGG1) plays a major role in the repair of 8-hydroxyguanine, one of the major forms of DNA damage generated by reactive oxygen species in tobacco smoke. If left unrepaired by hOGG1, 8-hydroxyguanine can produce G:C-to-T:A transversions. Recent studies have suggested that the hOGG1...

journal_title：International journal of cancer

authors： Hu YC,Ahrendt SA

更新日期：2005-04-10 00:00:00

abstract：:Effects of therapeutic and supratherapeutic concentrations of bosutinib, a dual Src/Abl tyrosine kinase inhibitor, on the corrected QT interval (QTc) in 60 healthy adults were assessed, according to ICH-E14 guidelines, in this 2-part, randomized, single-dose, double-blind, crossover, placebo- and open-label moxifloxac...

journal_title：International journal of cancer

authors： Abbas R,Hug BA,Leister C,Sonnichsen D

更新日期：2012-08-01 00:00:00

abstract：:A highly immunogenic variant of the murine L1210 leukemia cell (L1210/LN-1) for generation of tumor immunity has been obtained from culture of L1210 cells originally fused with human Lesch-Nyhan fibroblasts. In L1210/LN-1 cells, no human chromosomes were identified and chromosomes M1 and No. 1 carried by the parent L1...

journal_title：International journal of cancer

authors： Kawashima K,Nagura E,Watanabe E,Mizoguchi K,Saga S,Isobe K,Nakashima I,Yamada K,Oikawa T,Kojima K

更新日期：1983-10-15 00:00:00

abstract：:We transduced a human gastric carcinoma cell line, HR, with the interleukin 2 (IL-2) gene. Stable HR transfectants secreted nanogram quantities of biologically active IL-2 and had significantly increased expression of IL-2 mRNA relative to that in parental cells. Expression of intracellular IL-2 protein was not quanti...

journal_title：International journal of cancer

authors： Nagashima S,Kashii Y,Reichert TE,Suminami Y,Suzuki T,Whiteside TL

更新日期：1997-07-03 00:00:00

abstract：:To study the drug delivery to tumor by utilization of an oligopeptide transport activity, we examined the accumulation of dipeptides and the peptide-mimetic anti-cancer drug, bestatin, a substrate of oligopeptide transporter PepT1. Firstly, we established HeLa cells stably expressing human peptide transporter (hPepT1)...

journal_title：International journal of cancer

authors： Nakanishi T,Tamai I,Takaki A,Tsuji A

更新日期：2000-10-15 00:00:00

abstract：:Corpus uteri cancer is the most common gynecological malignancy in most developed countries. The disease is typically diagnosed at an early stage, is of endometrioid histologic subtype, and has a fairly good prognosis. Here, we describe hysterectomy-corrected mortality rates of corpus uteri cancer, overall and stratif...

journal_title：International journal of cancer

authors： Gustafson LW,Booth BB,Kahlert J,Ørtoft G,Mejlgaard E,Clarke MA,Wentzensen N,Rositch AF,Hammer A

更新日期：2021-02-01 00:00:00

abstract：:The International Classification of Childhood Cancer (ICCC) updates the widely used Birch and Marsden classification scheme. ICCC is based on the second edition of the International Classification of Diseases for Oncology (ICD-O-2). The purpose of the new classification is to accommodate important changes in recogniti...

journal_title：International journal of cancer

authors： Kramárová E,Stiller CA

更新日期：1996-12-11 00:00:00

abstract：:Desmoids represent the most important cause of death, after colorectal cancer, in patients affected with familial adenomatous polyposis (FAP), an inherited disease due to mutations in the APC gene. The aims of our study were to estimate the risk of developing desmoids in FAP patients and to evaluate the association be...

journal_title：International journal of cancer

authors： Bertario L,Russo A,Sala P,Eboli M,Giarola M,D'amico F,Gismondi V,Varesco L,Pierotti MA,Radice P,Hereditary Colorectal Tumours Registry.

更新日期：2001-03-20 00:00:00

abstract：:ERK and RSK2 drive proliferation and invasion of many cancers. Phosphoprotein enriched in astrocytes 15 (PEA15) binds ERK and RSK2 and high PEA15 levels can impair ERK- and RSK2-dependent transcription. PEA15 expression also inversely correlates with cell motility and invasiveness. We therefore tested PEA15 effects on...

journal_title：International journal of cancer

authors： Gawecka JE,Geerts D,Koster J,Caliva MJ,Sulzmaier FJ,Opoku-Ansah J,Wada RK,Bachmann AS,Ramos JW

更新日期：2012-10-01 00:00:00

abstract：:We obtained Thy-I-positive cells directly from growing methylcholanthrene-induced (MCA-1510) sarcomas using fluorescence-activated cell sorting, then cultured these lymphocytes in medium containing Interleukin-2 and tested their activity in vivo against various MCA-sarcoma lines with the Winn assay. We found that cult...

journal_title：International journal of cancer

authors： Mulé JJ,Forstrom JW,George E,Hellström I,Hellström KE

更新日期：1981-11-15 00:00:00

abstract：:Blood lipids have been associated with the development of a range of cancers, including breast, lung and colorectal cancer. For endometrial cancer, observational studies have reported inconsistent associations between blood lipids and cancer risk. To reduce biases from unmeasured confounding, we performed a bidirectio...

journal_title：International journal of cancer

authors： Kho PF,Amant F,Annibali D,Ashton K,Attia J,Auer PL,Beckmann MW,Black A,Brinton L,Buchanan DD,Chanock SJ,Chen C,Chen MM,Cheng THT,Cook LS,Crous-Bous M,Czene K,De Vivo I,Dennis J,Dörk T,Dowdy SC,Dunning AM,Dürst

更新日期：2021-01-15 00:00:00

abstract：:Early detection, clinical management and disease recurrence monitoring are critical areas in cancer treatment in which specific biomarker panels are likely to be very important in each of these key areas. We have previously demonstrated that levels of alpha-2-heremans-schmid-glycoprotein (AHSG), complement component C...

journal_title：International journal of cancer

authors： Dowling P,Clarke C,Hennessy K,Torralbo-Lopez B,Ballot J,Crown J,Kiernan I,O'Byrne KJ,Kennedy MJ,Lynch V,Clynes M

更新日期：2012-08-15 00:00:00

abstract：:In our previous experiments in Syrian hamsters the in vivo semiquantitative method of determination of the natural resistance-depressing (NRD) activity of tumor cells was described. It was demonstrated that inactivated cells of different tissue culture cell lines derived from in vivo tumors in contrast to normal, or i...

journal_title：International journal of cancer

authors： Deichman GI,Kluchareva TE,Kashkina LM,Matveeva VA,Vendrov EL,Zemtsova VI

更新日期：1982-09-15 00:00:00

abstract：:Loss of imprinting (LOI) of insulin-like growth factor 2 (IGF2) is a common event in many cancers and typically activates the maternally silenced allele. The resulting biallelic IGF2 expression correlates strongly with the hypomethylation of a differentially methylated region (DMR) near its promoter. It has also been ...

journal_title：International journal of cancer

authors： Cheng YW,Idrees K,Shattock R,Khan SA,Zeng Z,Brennan CW,Paty P,Barany F

更新日期：2010-08-01 00:00:00

abstract：:The activity of ecto-nucleotidases has been determined on intact cells from Burkitt lymphoma (BL) and lymphoblastoid cell lines established in vitro (LCLs). BL cells never express ecto-5'-nucleotidase (5'-N) and exhibit only low levels of ecto-ATPase activity, whereas LCL-cells usually express both enzymes to varying ...

journal_title：International journal of cancer

authors： Gutensohn W,Jahn H

更新日期：1988-03-15 00:00:00