Does polycystic ovary syndrome increase the disparity in metabolic syndrome and cardiovascular-related health for African-American women?


:There have been few formal studies of differences in the phenotype of PCOS among women of African-American ancestry. Generally, African-American women tend to have an adverse cardiovascular risk profile when compared with women of other racial groups. The metabolic syndrome is a clinical disorder that identifies individuals at risk for diabetes and cardiovascular disease. Preliminary studies support that both African-American and White women with PCOS have similar prevalences of the metabolic syndrome, suggesting that the diagnosis may not be associated with racial differences in cardiovascular risk factors.


Semin Reprod Med


Coney P,Ladson G,Sweet S,Legro RS




Has Abstract


2008-01-01 00:00:00












  • Endometriosis and Female Pelvic Pain.

    abstract::Endometriosis is a nonmalignant gynecologic disorder that can have a significant impact on a woman's quality of life with pelvic pain and possible lasting effects on one's fertility. Symptoms, when present, can be severe and affect many organ systems including the gastrointestinal and urinary systems. Other etiologies...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Kim JH,Han E

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  • Uterine receptivity and the ramifications of ovarian stimulation on endometrial function.

    abstract::Controlled ovarian stimulation (COS) is widely used in assisted reproduction techniques (ART). However, hormonal treatment induces endometrial alterations that may alter implantation rates compared with natural cycles. Endometrial alterations have been observed by histological and biochemical techniques. The recent de...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Horcajadas JA,Díaz-Gimeno P,Pellicer A,Simón C

    更新日期:2007-11-01 00:00:00

  • Contraceptive vaginal rings.

    abstract::Contraceptive vaginal rings (CVRs) contain sex steroids that diffuse through a plastic polymer ring at a constant rate and are absorbed directly through the vaginal epithelium into the systemic circulation. This delivery system provides many advantages over oral contraceptives (OCs), including avoidance of the first-p...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Harwood B,Mishell DR Jr

    更新日期:2001-12-01 00:00:00

  • Human embryo cryopreservation-methods, timing, and other considerations for optimizing an embryo cryopreservation program.

    abstract::The contribution of embryo cryopreservation to the birth rate per in vitro fertilization cycle has escalated from a rare subsidy to a vital tool that is called upon to augment the cycle outcome. Embryology laboratories must identify the embryo stage, quality criteria and methodology that will optimize their ability to...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Sparks AE

    更新日期:2015-03-01 00:00:00

  • Management of abnormal uterine bleeding in low- and high-resource settings: consideration of cultural issues.

    abstract::In non industrialized countries the incidence of heavy menstrual bleeding (HMB) appears to be similar to that of industrialized countries, although data is scanty. In low-resource settings, women with abnormal uterine bleeding (AUB) often delay seeking medical care because of cultural beliefs that a heavy red menstrua...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Haththotuwa R,Goonewardene M,Desai S,Senanayake L,Tank J,Fraser IS

    更新日期:2011-09-01 00:00:00

  • The Impact and Management of Subclinical Hypothyroidism for Improving Reproductive Outcomes such as Fertility and Miscarriage.

    abstract::Subclinical hypothyroidism has been found to be associated with adverse reproductive outcomes, such as infertility, miscarriage, preterm birth, and complications of pregnancy. Multiple studies have investigated the relationships between thyroid function, thyroid antibodies, fertility, and pregnancy. Thyroid autoimmuni...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Seungdamrong A

    更新日期:2016-11-01 00:00:00

  • Robot-assisted laparoscopy, natural orifice transluminal endoscopy, and single-site laparoscopy in reproductive surgery.

    abstract::Minimally invasive gynecologic surgery is continuously pushing its limits by embracing ever more sophisticated technology. This is also true for reproductive surgery, arguably the birthplace of gynecologic endoscopy, where minimally invasive treatment of uterine, tubal, ovarian, and peritoneal pathology has long becom...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Gargiulo AR,Nezhat C

    更新日期:2011-03-01 00:00:00

  • Evaluation of a Center of Research Excellence in Polycystic Ovary Syndrome as a Large-Scale Collaborative Research Translation Initiative, Including Evaluating Translation of Guideline Impact.

    abstract::Research translation and evaluation are often underconsidered in research design and implementation thus limiting research benefit to the end user. In this article, we first describe a best practice approach to evaluation, for a center of research excellence in polycystic ovary syndrome. Within this, we outline a comp...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章


    authors: Garad R,Kozica-Olenski S,Teede HJ

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  • Noncommunicable diseases.

    abstract::Noncommunicable diseases (NCDs), long considered diseases of little significance to global health, represent the greatest threat to economic development and human health. The main NCDs-diabetes, cancer, cardiovascular disease, and chronic respiratory disease-are the world's number one killer and bear the greatest burd...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章


    authors: Marrero S,Adashi EY

    更新日期:2015-01-01 00:00:00

  • In vitro maturation for patients with polycystic ovary syndrome.

    abstract::In vitro fertilization (IVF) with ovarian stimulation is an effective treatment for couples needing treatment with assisted reproductive technologies (ART) where polycystic ovary syndrome (PCOS) is coexisting. However, it is also associated with an increased risk of ovarian hyperstimulation syndrome. In vitro maturati...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Reinblatt SL,Buckett W

    更新日期:2008-01-01 00:00:00

  • Insights from the Women's Health Initiative: individualizing risk assessment for hormone therapy decisions.

    abstract::Identifying appropriate candidates for menopausal hormone therapy (HT) is challenging given the complex profile of risks and benefits associated with treatment. Most professional societies agree that HT should not be used for chronic disease prevention. Recent findings from the Women's Health Initiative and other rand...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Wild RA,Manson JE

    更新日期:2014-11-01 00:00:00

  • Epigenetic transgenerational effects of endocrine disruptors on male reproduction.

    abstract::Endocrine-disrupting chemicals generally function as steroid receptor signaling antagonists or agonists that influence development to promote adult-onset disease. Exposure to the endocrine disruptors during the initiation of male reproductive tract development interferes with the normal hormonal signaling and formatio...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Guerrero-Bosagna CM,Skinner MK

    更新日期:2009-09-01 00:00:00

  • In vitro maturation of oocytes.

    abstract::In vitro maturation of oocytes is a safe and effective treatment offered in some fertility centers for assisted reproduction, where immature oocytes are retrieved from unstimulated ovaries. Therefore, the procedure avoids ovarian stimulation with expensive gonadotropins, side effects of the medications, and risks such...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Rao GD,Tan SL

    更新日期:2005-08-01 00:00:00

  • Infertility and the environment: the medical context.

    abstract::Approximately 10 to 15% of the population experiences infertility. Although 85 to 90% of couples or individuals who experience infertility have a diagnosis for their infertility, underlying causes of infertility rarely are found. Extensive literature reporting adverse effects of environmental contaminants on wildlife ...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Giudice LC

    更新日期:2006-07-01 00:00:00

  • Discovery, chemistry, and reproductive pharmacology of asoprisnil and related 11beta-benzaldoxime substituted selective progesterone receptor modulators (SPRMs).

    abstract::Asoprisnil (J 867; benzaldehyde, 4-[(11beta, 17beta)-17-methoxy-17-(methoxymethyl)-3-oxoestra-4, 9-dien-11beta-yl]-, 1-oxime) is the prototype of a novel class 11beta-benzaldoxime-substituted selective progesterone receptor modulators (SPRMs) and the first-in-class SPRM to reach an advanced stage of clinical developme...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Schubert G,Elger W,Kaufmann G,Schneider B,Reddersen G,Chwalisz K

    更新日期:2005-02-01 00:00:00

  • Life plans and family-building options for women with primary ovarian insufficiency.

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    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Baker V

    更新日期:2011-07-01 00:00:00

  • Medical Management of Endometriosis in Patients with Chronic Pelvic Pain.

    abstract::Endometriosis is a common cause of pelvic pain in women of reproductive age. Traditional medical therapies are hormonal in nature, including estrogen-progestin contraceptives, progestins, and gonadotropin-releasing hormone (GnRH) agonists. Other hormonal options are androgens and aromatase inhibitors, with research al...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Bedaiwy MA,Allaire C,Yong P,Alfaraj S

    更新日期:2017-01-01 00:00:00

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    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Tan O,Carr BR

    更新日期:2012-12-01 00:00:00

  • Pelvic pain, adnexal masses, and ultrasound.

    abstract::Pelvic pain, acute or chronic, accounts for more than 10% of referrals to gynecologists. Pain accounts for more than 40% of gynecologic diagnostic laparoscopies. Predicting operative findings is critical in planning surgical interventions, as well as preoperative and postoperative medical therapy. Ultrasound is useful...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Shwayder JM

    更新日期:2008-05-01 00:00:00

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    abstract::Prior to the advent of modern minimally invasive surgery techniques, the primary surgical management of symptomatic leiomyomata for women desiring future fertility or uterine conservation was through laparotomy. Today, many cases of intramural and subserous leiomyomata are managed with laparoscopic myomectomy and sele...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Advincula AP,Song A

    更新日期:2004-05-01 00:00:00

  • Management of Endometriosis Involving the Urinary Tract.

    abstract::Endometriosis is a common cause of infertility and disabling pelvic pain in reproductive age women. The most widely accepted theory of its pathogenesis is the retrograde flow of menstrual products, although extra-abdominal and extrapelvic diagnoses have been made. After the pelvic peritoneum and gynecologic structures...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Ajao MO,Einarsson JI

    更新日期:2017-01-01 00:00:00

  • Aromatase and endometriosis.

    abstract::Aromatase p450 (p450arom) is the key enzyme for biosynthesis of estrogen, which is an essential hormone for the establishment and growth of endometriosis. There is no detectable aromatase enzyme activity in normal endometrium; therefore, estrogen is not locally produced in endometrium. Endometriosis tissue, however, c...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Bulun SE,Fang Z,Imir G,Gurates B,Tamura M,Yilmaz B,Langoi D,Amin S,Yang S,Deb S

    更新日期:2004-02-01 00:00:00

  • Microbiota and pelvic inflammatory disease.

    abstract::Female genital tract microbiota play a crucial role in maintaining health. Disequilibrium of the microbiota has been associated with increased risk of pelvic infections. In recent years, culture-independent molecular techniques have expanded understanding of the composition of genital microbiota and the dynamic nature...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Sharma H,Tal R,Clark NA,Segars JH

    更新日期:2014-01-01 00:00:00

  • Impact of extracellular matrix remodeling on ovulation and the folliculo-luteal transition.

    abstract::Follicular rupture and the transformation of an estrogenic preovulatory follicle into a highly vascularized corpus luteum capable of producing large quantities of progesterone are required for the establishment of pregnancy. These processes are dependent upon the precise remodeling of the ovarian extracellular matrix ...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Curry TE Jr,Smith MF

    更新日期:2006-09-01 00:00:00

  • Developmental Origins of Hypothalamic Cells Controlling Reproduction.

    abstract::The hypothalamus-pituitary-gonadal (HPG) axis is the most critical modulator of reproductive function. Genetic or environmental insults to the HPG axis during developmental windows can persist into adulthood, and processes such as gonadal hormone synthesis, timing of puberty, and fertility can be affected. At the leve...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Biehl MJ,Raetzman LT

    更新日期:2017-03-01 00:00:00

  • Wnt Signaling in Stem Cells and Tumor Stem Cells.

    abstract::The Wnt signaling cascade is critically important in stem cell biology, both in homeostatic maintenance and repair and regeneration of tissues and organs, through their respective somatic stem cells (SSCs). However, aberrant Wnt signaling is associated with a wide array of tumor types and Wnt signaling is important in...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Kahn M

    更新日期:2015-09-01 00:00:00

  • Anejaculation: an electrifying approach.

    abstract::Anejaculation within the context of a male infertility evaluation can be a distressing condition for patients. A variety of causes for anejaculation have been identified, and although the condition cannot be reversed, in many cases a minimally invasive treatment is feasible, allowing the patient to pursue his desire f...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Ohl DA,Quallich SA,Sønksen J,Brackett NL,Lynne CM

    更新日期:2009-03-01 00:00:00

  • Neuroendocrine changes with reproductive aging in women.

    abstract::Aging has dramatic effects on the reproductive system in women. Undoubtedly, the most notable changes in the neuroendocrine axis arise from the loss of ovarian function, and thus, the loss of negative feedback on the hypothalamus and pituitary. Progressive decreases in inhibin B and inhibin A result in an early increa...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Hall JE

    更新日期:2007-09-01 00:00:00

  • A new function for the LH/CG receptor: transcytosis of hormone across the endothelial barrier in target organs.

    abstract::Gonadotropins cross the vascular endothelial barrier to reach their target organs. Hormone concentrations in blood are very low and fluctuate rapidly to give sharp biological effects. Nonspecific transendothelial transport mechanisms are slow and markedly concentration dependent. There is thus a need for specific tran...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Ghinea N,Milgrom E

    更新日期:2001-01-01 00:00:00

  • Complementary Therapies and Medicines and Reproductive Medicine.

    abstract::Complementary therapies and medicines are a broad and diverse range of treatments, and are frequently used by women and their partners during the preconception period to assist with infertility, and to address pregnancy-related conditions. Despite frequent use, the evidence examining the efficacy, effectiveness, and s...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审


    authors: Smith CA,Armour M,Ee C

    更新日期:2016-03-01 00:00:00