Ovarian hyperstimulation syndrome prevention strategies: Luteal support strategies to optimize pregnancy success in cycles with gonadotropin-releasing hormone agonist ovulatory trigger.

abstract：:The birth of a child with ambiguous genitalia is a challenging and distressing event for the family and physician and one with life-long consequences. Most disorders of sexual differentiation (DSD) associated with ambiguous genitalia are the result either of inappropriate virilization of girls or incomplete virilizati...

journal_title：Seminars in reproductive medicine

authors： Wilson JD,Rivarola MA,Mendonca BB,Warne GL,Josso N,Drop SL,Grumbach MM

更新日期：2012-10-01 00:00:00

abstract：:Couples experiencing recurrent pregnancy loss are often concerned that toxins within the environment have contributed to their reproductive difficulty. Questions posed by these couples to their health care providers are difficult to answer because scientifically accurate information regarding the reproductive impact o...

journal_title：Seminars in reproductive medicine

authors： Gardella JR,Hill JA 3rd

更新日期：2000-01-01 00:00:00

abstract：:Analysis of published series reveals that no more than a fourth of subfertile patients undergoing surgery for peritoneal endometriotic implants, rectovaginal endometriotic lesions, or recurrent endometriomas achieved conception spontaneously. First-line surgery for ovarian endometriotic cysts appears associated with a...

journal_title：Seminars in reproductive medicine

authors： Berlanda N,Vercellini P,Somigliana E,Frattaruolo MP,Buggio L,Gattei U

更新日期：2013-03-01 00:00:00

abstract：:This study reviews systematically the effectiveness of management strategies for carriers of a reciprocal translocation involving two chromosomes, ascertained on the basis of recurrent pregnancy loss. Subsequent pregnancy outcomes were tabulated based on whether management was medical or involved in vitro fertilizatio...

journal_title：Seminars in reproductive medicine

authors： Hirshfeld-Cytron J,Sugiura-Ogasawara M,Stephenson MD

更新日期：2011-11-01 00:00:00

abstract：:Noncommunicable diseases (NCDs), long considered diseases of little significance to global health, represent the greatest threat to economic development and human health. The main NCDs-diabetes, cancer, cardiovascular disease, and chronic respiratory disease-are the world's number one killer and bear the greatest burd...

journal_title：Seminars in reproductive medicine

authors： Marrero S,Adashi EY

更新日期：2015-01-01 00:00:00

abstract：:The ability of glycerol to protect cells from freezing injury was discovered accidentally. The subsequent development of cryopreservation techniques has had a huge impact in many fields, most notably in reproductive medicine. Freezing injury has been shown to have two components, direct damage from the ice crystals an...

journal_title：Seminars in reproductive medicine

authors： Pegg DE

更新日期：2002-02-01 00:00:00

abstract：:Exposure to gonadotoxic agents for treating cancer and other diseases or postponement of maternity jeopardize the prospects of genetic parenthood and are major factors driving the development of fertility preservation technologies. Although its mainstays, cryopreservation and vitrification, have been adopted from infe...

journal_title：Seminars in reproductive medicine

authors： Gosden RG

更新日期：2009-11-01 00:00:00

abstract：:During the menstrual cycle, human endometrium undergoes extensive cyclic morphologic and biochemical modifications in preparation for embryo implantation. These processes are highly regulated by ovarian steroids and various locally expressed gene products and involve inflammatory reaction, apoptosis, cell proliferatio...

journal_title：Seminars in reproductive medicine

authors： Pan Q,Chegini N

更新日期：2008-11-01 00:00:00

abstract：:Old World monkeys display physiological responses to steroid hormones that are similar to those of women. In this review, we describe cyclic morphological changes that take place within the uterus of Old World primates during the menstrual cycle. In primates, estrogen stimulates endometrial growth in the follicular ph...

journal_title：Seminars in reproductive medicine

authors： Slayden OD

更新日期：2014-09-01 00:00:00

abstract：:There have been few formal studies of differences in the phenotype of PCOS among women of African-American ancestry. Generally, African-American women tend to have an adverse cardiovascular risk profile when compared with women of other racial groups. The metabolic syndrome is a clinical disorder that identifies indiv...

journal_title：Seminars in reproductive medicine

authors： Coney P,Ladson G,Sweet S,Legro RS

更新日期：2008-01-01 00:00:00

abstract：:Asoprisnil (J 867; benzaldehyde, 4-[(11beta, 17beta)-17-methoxy-17-(methoxymethyl)-3-oxoestra-4, 9-dien-11beta-yl]-, 1-oxime) is the prototype of a novel class 11beta-benzaldoxime-substituted selective progesterone receptor modulators (SPRMs) and the first-in-class SPRM to reach an advanced stage of clinical developme...

journal_title：Seminars in reproductive medicine

authors： Schubert G,Elger W,Kaufmann G,Schneider B,Reddersen G,Chwalisz K

更新日期：2005-02-01 00:00:00

abstract：:Puberty is a fundamental developmental event in the lifespan of any individual, when sexual and somatic maturation is completed, and reproductive capacity is achieved. While the tempo of puberty is under strong genetic determination, it is also modulated by a wide array of internal and environmental cues, including, p...

journal_title：Seminars in reproductive medicine

authors： Barroso A,Roa J,Tena-Sempere M

更新日期：2019-07-01 00:00:00

abstract：:Androgen receptors are present in numerous tissues throughout the female body, and knowledge of the specific actions of androgens at different sites is increasing, along with the understanding of their contribution to various pathophysiological states. This article reviews the physiology of androgens (testosterone and...

journal_title：Seminars in reproductive medicine

authors： Davison SL,Bell R

更新日期：2006-04-01 00:00:00

abstract：:Microfluidics is a young but established field that holds significant potential for scientific discovery. The utility of microfluidics can improve our knowledge of basic biology as well as expand our understanding in specialized areas such as assisted reproduction and stem cell developmental biology. This review descr...

journal_title：Seminars in reproductive medicine

authors： Smith GD,Swain JE,Bormann CL

更新日期：2011-01-01 00:00:00

abstract：:Whereas the importance of close monitoring and tight glycemic control in diabetic pregnancies cannot be ignored, the growing body of knowledge surrounding the different effects of diabetes mellitus on the earliest stages of reproduction underscores the need for aggressive screening among reproductive-aged women at ris...

journal_title：Seminars in reproductive medicine

authors： Jungheim ES,Moley KH

更新日期：2008-03-01 00:00:00

abstract：:Over the past decade there has been a resurgence of interest in the culture media used in clinical in vitro fertilization. Unfortunately, during this time more confusion than consensus appears to have developed regarding the composition of these media. In order to facilitate a clearer understanding of this field, it i...

journal_title：Seminars in reproductive medicine

authors： Gardner DK,Pool TB,Lane M

更新日期：2000-01-01 00:00:00

abstract：:Estrogens are frequently used in reproductive medicine. The Women's Health Initiative trial found that the risks of menopausal hormone therapy (MHT) exceed the benefits. The estrogens in MHT, however, were introduced prior to our understanding of the mechanism of action of estrogens. Estrogen signaling is highly compl...

journal_title：Seminars in reproductive medicine

authors： Leitman DC,Paruthiyil S,Yuan C,Herber CB,Olshansky M,Tagliaferri M,Cohen I,Speed TP

更新日期：2012-01-01 00:00:00

abstract：:Obesity is a pandemic and is associated with multiple medical problems including subfertility. Male obesity has been associated with altered semen parameters and reproductive hormonal levels, including a reduced testosterone:estradiol (T:E₂) ratio. Treatment methods employed for obesity-related male subfertility inclu...

journal_title：Seminars in reproductive medicine

authors： Stephens SM,Polotsky AJ

更新日期：2013-07-01 00:00:00

abstract：:The contribution of embryo cryopreservation to the birth rate per in vitro fertilization cycle has escalated from a rare subsidy to a vital tool that is called upon to augment the cycle outcome. Embryology laboratories must identify the embryo stage, quality criteria and methodology that will optimize their ability to...

journal_title：Seminars in reproductive medicine

authors： Sparks AE

更新日期：2015-03-01 00:00:00

abstract：:Randomized clinical trials (RCTs) have been used to assess interventions affecting health since biblical times. They provide the most valid means of measuring the true effects of intervention compared with no treatment or placebo. Although they can also be used to assess the value of diagnostic tests, this article foc...

journal_title：Seminars in reproductive medicine

authors： Hughes EG

更新日期：2003-02-01 00:00:00

abstract：:HOX genes, encoding homeodomain transcription factors, are dynamically expressed in endometrium, where they are necessary for endometrial growth, differentiation, and implantation. In human endometrium, the expression of HOXA10 and HOXA11 is driven by sex steroids, with peak expression occurring at time of implantatio...

journal_title：Seminars in reproductive medicine

authors： Cakmak H,Taylor HS

更新日期：2010-01-01 00:00:00

abstract：:Anejaculation within the context of a male infertility evaluation can be a distressing condition for patients. A variety of causes for anejaculation have been identified, and although the condition cannot be reversed, in many cases a minimally invasive treatment is feasible, allowing the patient to pursue his desire f...

journal_title：Seminars in reproductive medicine

authors： Ohl DA,Quallich SA,Sønksen J,Brackett NL,Lynne CM

更新日期：2009-03-01 00:00:00

abstract：:Intrauterine insemination (IUI) is a widely used fertility treatment for couples with male and/or non-male factor infertility and is a relatively simple and inexpensive procedure. When used for unexplained infertility, IUI combined with ovarian stimulation increases the pregnancy rates, but evidence does not support t...

journal_title：Seminars in reproductive medicine

authors： Kim YJ,Park CW,Ku SY

更新日期：2014-07-01 00:00:00

abstract：:Labor initiation is a complex process that remains to be fully elucidated. An area of active research involves the study of the different mechanisms that may lead to successful signaling for parturition. This review focuses on the fetal-derived signals that lead to the initiation of labor. These signals may also play ...

journal_title：Seminars in reproductive medicine

authors： Beshay VE,Carr BR,Rainey WE

更新日期：2007-01-01 00:00:00

abstract：:Since 2004, assisted conception is encompassed by the European Directive on the Quality and Safety of Tissues and Cells (2004/23/EC). The aim of a standard for quality and safety is to minimize risks of errors, contamination, and accidents and to maximize efficiency of use. This article presents a case study of the im...

journal_title：Seminars in reproductive medicine

authors： Willemen D,D'Hooghe T,Knoops I,De Neubourg D,Spiessens C

更新日期：2012-06-01 00:00:00

abstract：:Contraceptive vaginal rings (CVRs) contain sex steroids that diffuse through a plastic polymer ring at a constant rate and are absorbed directly through the vaginal epithelium into the systemic circulation. This delivery system provides many advantages over oral contraceptives (OCs), including avoidance of the first-p...

journal_title：Seminars in reproductive medicine

authors： Harwood B,Mishell DR Jr

更新日期：2001-12-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) has become increasingly common over recent years and is associated with reproductive features as well as cardiometabolic risk factors, including visceral obesity, dyslipidemia and impaired glucose homeostasis, and potentially cardiovascular disease. Emerging evidence suggests that thes...

journal_title：Seminars in reproductive medicine

authors： Shorakae S,Teede H,de Courten B,Lambert G,Boyle J,Moran LJ

更新日期：2015-07-01 00:00:00

abstract：:Follicular rupture and the transformation of an estrogenic preovulatory follicle into a highly vascularized corpus luteum capable of producing large quantities of progesterone are required for the establishment of pregnancy. These processes are dependent upon the precise remodeling of the ovarian extracellular matrix ...

journal_title：Seminars in reproductive medicine

authors： Curry TE Jr,Smith MF

更新日期：2006-09-01 00:00:00

abstract：:Induction and patterning of the testis occurs over a brief window of time. Before male-specific morphogenesis, the gonad primordium is bipotential and capable of developing into either an ovary or testis. However, expression of the transcription factor SRY initiates male development and induces patterning, proliferati...

journal_title：Seminars in reproductive medicine

authors： Cool J,Capel B

更新日期：2009-01-01 00:00:00

abstract：:Vasomotor symptoms, including hot flushes and night sweats, pose a significant symptomatic burden to women undergoing menopause, and negatively impact on both their physical and psychological well-being. Management of these symptoms can be challenging, with the use of conventional hormone replacement therapy limited b...

journal_title：Seminars in reproductive medicine

authors： Modi M,Dhillo WS

更新日期：2019-05-01 00:00:00