Contraceptive vaginal rings.

abstract：:Whereas the importance of close monitoring and tight glycemic control in diabetic pregnancies cannot be ignored, the growing body of knowledge surrounding the different effects of diabetes mellitus on the earliest stages of reproduction underscores the need for aggressive screening among reproductive-aged women at ris...

journal_title：Seminars in reproductive medicine

authors： Jungheim ES,Moley KH

更新日期：2008-03-01 00:00:00

abstract：:Aging has dramatic effects on the reproductive system in women. Undoubtedly, the most notable changes in the neuroendocrine axis arise from the loss of ovarian function, and thus, the loss of negative feedback on the hypothalamus and pituitary. Progressive decreases in inhibin B and inhibin A result in an early increa...

journal_title：Seminars in reproductive medicine

authors： Hall JE

更新日期：2007-09-01 00:00:00

abstract：:Analysis of published series reveals that no more than a fourth of subfertile patients undergoing surgery for peritoneal endometriotic implants, rectovaginal endometriotic lesions, or recurrent endometriomas achieved conception spontaneously. First-line surgery for ovarian endometriotic cysts appears associated with a...

journal_title：Seminars in reproductive medicine

authors： Berlanda N,Vercellini P,Somigliana E,Frattaruolo MP,Buggio L,Gattei U

更新日期：2013-03-01 00:00:00

abstract：:As fertility rates among women of advanced reproductive age have steadily increased, so has the utilization of fertility services. National health policies provide infertility treatment coverage in several developed countries; however, in the United States infertility treatment is largely privately funded, resulting i...

journal_title：Seminars in reproductive medicine

authors： Levens ED,Richter KS,Levy MJ

更新日期：2013-05-01 00:00:00

abstract：:Labor initiation is a complex process that remains to be fully elucidated. An area of active research involves the study of the different mechanisms that may lead to successful signaling for parturition. This review focuses on the fetal-derived signals that lead to the initiation of labor. These signals may also play ...

journal_title：Seminars in reproductive medicine

authors： Beshay VE,Carr BR,Rainey WE

更新日期：2007-01-01 00:00:00

abstract：:Premature ovarian failure (POF) is a disorder characterized by lack of ovulation and elevated levels of serum gonadotropins before the age of 40. The etiology of POF is not known but different environmental and genetic factors are involved, suggesting high heterogeneity of the disorder. The involvement of X-linked gen...

journal_title：Seminars in reproductive medicine

authors： Bione S,Toniolo D

更新日期：2000-01-01 00:00:00

abstract：:Inhibin is a dimeric glycoprotein that suppresses follicle-stimulating hormone (FSH) secretion from the pituitary. Two bioactive forms of inhibin exist, inhibin A and B. The availability of specific immunoassays for each of the isoforms has enabled the study of the individual inhibins and their physiological roles. In...

journal_title：Seminars in reproductive medicine

authors： O'Connor AE,De Kretser DM

更新日期：2004-08-01 00:00:00

abstract：:Endocrine-disrupting chemicals generally function as steroid receptor signaling antagonists or agonists that influence development to promote adult-onset disease. Exposure to the endocrine disruptors during the initiation of male reproductive tract development interferes with the normal hormonal signaling and formatio...

journal_title：Seminars in reproductive medicine

authors： Guerrero-Bosagna CM,Skinner MK

更新日期：2009-09-01 00:00:00

abstract：:Trophoblast cells of the murine placenta are derived from the trophectoderm (TE) cells of the preimplantation embryo. Establishment of the TE cell lineage is the result of a cell segregation event early in blastomere division. Models of cell lineage segregation suggest it is driven by the internalization of spatial in...

journal_title：Seminars in reproductive medicine

authors： Underhill LA,Robins JC

更新日期：2016-01-01 00:00:00

abstract：:Endometriosis is a common cause of pelvic pain in women of reproductive age. Traditional medical therapies are hormonal in nature, including estrogen-progestin contraceptives, progestins, and gonadotropin-releasing hormone (GnRH) agonists. Other hormonal options are androgens and aromatase inhibitors, with research al...

journal_title：Seminars in reproductive medicine

authors： Bedaiwy MA,Allaire C,Yong P,Alfaraj S

更新日期：2017-01-01 00:00:00

abstract：:Obesity is a pandemic and is associated with multiple medical problems including subfertility. Male obesity has been associated with altered semen parameters and reproductive hormonal levels, including a reduced testosterone:estradiol (T:E₂) ratio. Treatment methods employed for obesity-related male subfertility inclu...

journal_title：Seminars in reproductive medicine

authors： Stephens SM,Polotsky AJ

更新日期：2013-07-01 00:00:00

abstract：:In vitro fertilization (IVF) with ovarian stimulation is an effective treatment for couples needing treatment with assisted reproductive technologies (ART) where polycystic ovary syndrome (PCOS) is coexisting. However, it is also associated with an increased risk of ovarian hyperstimulation syndrome. In vitro maturati...

journal_title：Seminars in reproductive medicine

authors： Reinblatt SL,Buckett W

更新日期：2008-01-01 00:00:00

abstract：:Endometriosis is a common cause of infertility and disabling pelvic pain in reproductive age women. The most widely accepted theory of its pathogenesis is the retrograde flow of menstrual products, although extra-abdominal and extrapelvic diagnoses have been made. After the pelvic peritoneum and gynecologic structures...

journal_title：Seminars in reproductive medicine

authors： Ajao MO,Einarsson JI

更新日期：2017-01-01 00:00:00

abstract：:The hypothalamus-pituitary-gonadal (HPG) axis is the most critical modulator of reproductive function. Genetic or environmental insults to the HPG axis during developmental windows can persist into adulthood, and processes such as gonadal hormone synthesis, timing of puberty, and fertility can be affected. At the leve...

journal_title：Seminars in reproductive medicine

authors： Biehl MJ,Raetzman LT

更新日期：2017-03-01 00:00:00

abstract：:During most of gestation, the fetal adrenal gland is almost solely dedicated to the production of dehydroepiandrosterone sulfate (DHEA-S). This specialized ability of the fetal adrenal is unique to primates and occurs because of a specialized fetal zone that composes the bulk of the fetal adrenal gland. Morphologicall...

journal_title：Seminars in reproductive medicine

authors： Rainey WE,Rehman KS,Carr BR

更新日期：2004-11-01 00:00:00

abstract：:Subclinical hypothyroidism has been found to be associated with adverse reproductive outcomes, such as infertility, miscarriage, preterm birth, and complications of pregnancy. Multiple studies have investigated the relationships between thyroid function, thyroid antibodies, fertility, and pregnancy. Thyroid autoimmuni...

journal_title：Seminars in reproductive medicine

authors： Seungdamrong A

更新日期：2016-11-01 00:00:00

abstract：:Research translation and evaluation are often underconsidered in research design and implementation thus limiting research benefit to the end user. In this article, we first describe a best practice approach to evaluation, for a center of research excellence in polycystic ovary syndrome. Within this, we outline a comp...

journal_title：Seminars in reproductive medicine

authors： Garad R,Kozica-Olenski S,Teede HJ

更新日期：2018-01-01 00:00:00

abstract：:There have been few formal studies of differences in the phenotype of PCOS among women of African-American ancestry. Generally, African-American women tend to have an adverse cardiovascular risk profile when compared with women of other racial groups. The metabolic syndrome is a clinical disorder that identifies indiv...

journal_title：Seminars in reproductive medicine

authors： Coney P,Ladson G,Sweet S,Legro RS

更新日期：2008-01-01 00:00:00

abstract：:Anejaculation within the context of a male infertility evaluation can be a distressing condition for patients. A variety of causes for anejaculation have been identified, and although the condition cannot be reversed, in many cases a minimally invasive treatment is feasible, allowing the patient to pursue his desire f...

journal_title：Seminars in reproductive medicine

authors： Ohl DA,Quallich SA,Sønksen J,Brackett NL,Lynne CM

更新日期：2009-03-01 00:00:00

abstract：:In this article the role of LH receptor gene mutations in patients with aberrant sex differentiation is discussed. In a dominant autosomal familial form of precocious puberty in boys (familial male-limited precocious puberty) LH receptor gene mutations have been identified. These single amino acid changes, mostly foun...

journal_title：Seminars in reproductive medicine

authors： Themmen AP,Verhoef-Post M

更新日期：2002-08-01 00:00:00

abstract：:Old World monkeys display physiological responses to steroid hormones that are similar to those of women. In this review, we describe cyclic morphological changes that take place within the uterus of Old World primates during the menstrual cycle. In primates, estrogen stimulates endometrial growth in the follicular ph...

journal_title：Seminars in reproductive medicine

authors： Slayden OD

更新日期：2014-09-01 00:00:00

abstract：:Pregnancy results in major changes in the hypothalamo-pituitary-adrenal (HPA) axis, which in turn influence fetal growth and the timing of labor. From the beginning of the second trimester maternal cortisol secretion increases, and in late pregnancy the placenta, in large part mediated through corticotroph-releasing h...

journal_title：Seminars in reproductive medicine

authors： Trainer PJ

更新日期：2002-11-01 00:00:00

abstract：:Controlled ovarian stimulation (COS) is widely used in assisted reproduction techniques (ART). However, hormonal treatment induces endometrial alterations that may alter implantation rates compared with natural cycles. Endometrial alterations have been observed by histological and biochemical techniques. The recent de...

journal_title：Seminars in reproductive medicine

authors： Horcajadas JA,Díaz-Gimeno P,Pellicer A,Simón C

更新日期：2007-11-01 00:00:00

abstract：:Chromosome abnormalities are extremely common in human oocytes and embryos and are associated with a variety of negative outcomes for both natural cycles and those using assisted conception techniques. Embryos containing the wrong number of chromosomes (aneuploidy) may fail to implant in the uterus, miscarry, or lead ...

journal_title：Seminars in reproductive medicine

authors： Fragouli E,Wells D

更新日期：2012-08-01 00:00:00

abstract：:Obesity-related infertility is one of the most common problems of reproductive-age obese women who desire childbearing. The various types of bariatric surgeries have proved effective in controlling excessive weight gain, improving fertility, and preventing certain maternal and fetal complications in these women. This ...

journal_title：Seminars in reproductive medicine

authors： Tan O,Carr BR

更新日期：2012-12-01 00:00:00

abstract：:Androgen receptors are present in numerous tissues throughout the female body, and knowledge of the specific actions of androgens at different sites is increasing, along with the understanding of their contribution to various pathophysiological states. This article reviews the physiology of androgens (testosterone and...

journal_title：Seminars in reproductive medicine

authors： Davison SL,Bell R

更新日期：2006-04-01 00:00:00

abstract：:The constructs and the provision of preconception and obstetrical care have historically been based on the assumption of heterosexuality, and have often excluded lesbian women. However, due to significant strides in lesbian, gay, bisexual, transgender, and queer (LGBTQ) civil rights, more lesbian women desire to creat...

journal_title：Seminars in reproductive medicine

authors： Bushe S,Romero IL

更新日期：2017-09-01 00:00:00

abstract：:Primary ovarian insufficiency (POI) compromises a woman's chance of conceiving with her own oocytes. Although biomarkers such as serum follicle-stimulating hormone, serum antimüllerian hormone, and assessment of antral follicle count by transvaginal ultrasound can give some general idea about ovarian activity and perh...

journal_title：Seminars in reproductive medicine

authors： Baker V

更新日期：2011-07-01 00:00:00

abstract：:Reproductive performance may be an important variable in treatment selection for unruptured ectopic pregnancy. The impact of treatment choice on reproductive performance is not known. We searched the literature and then tabulated published case reports on laparoscopic salpingostomy, multiple-dose methotrexate, single-...

journal_title：Seminars in reproductive medicine

authors： Buster JE,Krotz S

更新日期：2007-03-01 00:00:00

abstract：:Soon after implantation, cell lineages bifurcate into future somatic and germ cells. Canonical expression of germ cell-specific genes continues during and after their migration to the gonadal ridge, where, after further cell cycles, they enter meiosis, form syncytial clusters, and arrest at diplotene for folliculogene...

journal_title：Seminars in reproductive medicine

authors： Gosden RG

更新日期：2013-11-01 00:00:00