Abstract：
:The effects of human alpha-, beta-, or gamma-interferon (IFN) on the replication and production of human T-lymphotrophic virus type-I (HTLV-I) were investigated in a human T-cell line, MT-2. Virus transmission and production estimated by syncytium formation and HTLV-I-associated reverse transcriptase (RT) activity were strongly suppressed in the presence of alpha- and beta-IFN, but not gamma-IFN. However, the expression of virus specific proteins gp46 but not p19, p24, p28, p36, and gp68 was affected with IFNs as revealed by Western blotting analysis. Electron microscopic observations showed that some of the HTLV-I particles were trapped in the intracellular vacuoles in the presence of high doses of alpha- or beta-IFN. Continuous supply of IFNs appeared to be essential for the constant suppression of RT activity. These results suggest that alpha- and beta-IFN do not inhibit HTLV-I gene expression strikingly but suppress processing or assembly of virus proteins and/or releasing of virions in the late phase of maturation.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Oka T,Ohtsuki Y,Sonobe H,Furihata M,Miyoshi Idoi
10.1007/BF01310623subject
Has Abstractpub_date
1990-01-01 00:00:00pages
63-73issue
1-2eissn
0304-8608issn
1432-8798journal_volume
115pub_type
杂志文章abstract：:Japanese encephalitis virus (JEV) is a zoonotic pathogen transmitted by Culex mosquitoes and is the leading cause of viral encephalitis in humans. JEV infection of swine, which are the main amplifying hosts for JEV, can cause reproductive failure in sows; in boars it can cause testitis and infertility. The prevalence ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-019-04218-9
更新日期：2019-06-01 00:00:00
abstract：:Coxsackievirus B (CVB) can cause aseptic meningitis, myocarditis and respiratory disease, especially in newborn infants. To compare the susceptibility to CVB infection of fetal and adult mice, we prepared primary alveolar epithelial cells (AECs) from lungs of BALB/c mice. In contrast to fetal mouse AECs, those of adul...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1254-6
更新日期：2012-06-01 00:00:00
abstract：:The nucleotide sequences of the SH gene of 45 new mumps virus isolates derived from different parts of Europe, Canada and USA were determined. A phylogenetic tree was constructed which confirmed the existence of three major clusters. While clustering according to geographical origin was clear in some cases each of the...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050073
更新日期：1997-01-01 00:00:00
abstract：:A flow cytometric virus binding assay that directly visualizes the binding of infectious bursal disease virus (IBDV) to its target cells was established. The chicken B lymphoblastoid cell line, LSCC-BK3, which is permissive for IBDV infection, bound high levels of the virus. Another B lymphoblastoid cell line, LSCC-11...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050464
更新日期：1998-01-01 00:00:00
abstract：:Chilo iridescent virus (CIV) belongs to the family Iridoviridae, which are icosahedral cytoplasmic DNA viruses with large, linear, and circularly permuted genomes. Previous studies on infected-cell-specific polypeptides suggested temporal regulation of CIV gene expression. Recently, we demonstrated three temporal clas...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-003-0232-4
更新日期：2004-04-01 00:00:00
abstract：:The contribution of expression of human cytomegalovirus (HCMV) immediate early (IE) genes to the rapid and transient increase in cellular (c)-oncogene (fos, jun, myc) transcription following HCMV infection was investigated. A partial temporal overlap was observed between the increases in c-oncogene RNA levels and the ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314027
更新日期：1991-01-01 00:00:00
abstract：:A virus isolated from sorghum in Nigeria has been partially characterized. It was tested by enzyme-linked immunosorbent assay (ELISA) using antisera to Maize dwarf mosaic virus, Johnsongrass mosaic virus (JGMV), Sugarcane mosaic virus strain-MDB, Sorghum mosaic virus, and Zea mosaic virus. A partial host range, sympto...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-004-0411-y
更新日期：2005-03-01 00:00:00
abstract：:Pigeon circovirus (PiCV) is taxonomically classified as a member of the Circovirus genus, family Circoviridae. The virus contains a single stranded DNA genome of approximately 2 kb, with minor length variations among different isolates. The occurrence of PiCV infections in pigeons (Columba livia) has been documented w...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-3990-8
更新日期：2018-11-01 00:00:00
abstract：:Immunofluorescence assay using monospecific and monoclonal antibodies to the 65 K major protein of human cytomegalovirus (HCMV) was carried out to monitor the expression of this protein in infected cells. Regardless of differences in the reactivity of the monoclonal antibodies, as determined by immunoblotting and immu...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314653
更新日期：1988-01-01 00:00:00
abstract：:Morphological studies of EIAV reveal knobs on the surface of the particles, conically and tubularly shaped cores, budding particles with dense crescents directly underlying the plasma membrane, and distinct intracytoplasmic structures in infected cells. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315055
更新日期：1977-01-01 00:00:00
abstract：:11 African and two German IBDV strains isolated in the mid '80s from field outbreaks in vaccinated and unvaccinated chicken flocks displayed features of very virulent (vv) IBDV strains. The sequence data of the VP2 variable region and phylogenetic analysis confirm that these strains can be grouped within vv IBDV strai...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050009
更新日期：2000-01-01 00:00:00
abstract：:Serologic and virologic prevalence of infection with different swine influenza virus (SIV) subtypes was investigated using swine sera, nasal swabs and lung samples that had been submitted for a diagnosis to the Minnesota Veterinary Diagnostic Laboratory. A total of 111,418 pig sera were tested for SIV antibody between...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-002-0788-4
更新日期：2002-06-01 00:00:00
abstract：:Cumulative studies have demonstrated that dengue virus infection results in the induction of apoptosis of certain cells in vitro. Moreover, apoptosis of microvascular endothelial cells in the brain and in the intestinal serosa has been demonstrated postmortem in dengue virus (DENV)-infected patients. In this work, hum...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-009-0396-7
更新日期：2009-01-01 00:00:00
abstract：:The movement protein (MP) of tobacco mosaic virus (TMV) mediates the transport of viral RNA from infected cells to neighboring uninfected cells via plasmodesmata by interacting with putative host factors. To find such host factors, we screened tobacco proteins using the yeast two-hybrid system. NtMPIP1, a novel subset...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-009-0397-6
更新日期：2009-01-01 00:00:00
abstract：:We constructed a recombinant baculovirus encoding a dengue (DEN)-2 virus envelope glycoprotein truncated of 102 amino acids (aa) at its C-terminus (D2E delta 102). The production, processing and transportation of the recombinant protein in baculovirus-infected Spodoptera frugiperda (Sf9) cells and its immunogenic prop...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309465
更新日期：1994-01-01 00:00:00
abstract：:Sera and bronchial washings from normal mice and from mice previously infected with influenza virus were analyzed for their concentration of four immunoglobulin (Ig) classes by the method of single radial immunodiffusion and for their content of specific antibody of these Ig classes by the immunofluorescent method. Ig...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314846
更新日期：1977-01-01 00:00:00
abstract：:This report describes the first isolation and partial characterization of a herpesvirus from the harbor seal (Phoca vitulina). The virus was isolated during a disease outbreak in a group of young seals nursed in a seal orphanage in The Netherlands. Almost half of the seals died with symptoms of acute pneumonia and foc...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309828
更新日期：1985-01-01 00:00:00
abstract：:Virus isolate Y3V, obtained from tobacco showing leaf curl symptoms in Yunnan, China, had particles with the size and morphology typical of geminiviruses. In reactions with a set of monoclonal antibodies raised against begomoviruses, Y3V was readily differentiated from two previously studied Chinese Begomovirus isolat...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050170081
更新日期：2001-08-01 00:00:00
abstract：:MicroRNAs (miRNAs) are a new class of well-conserved small noncoding RNAs that mediate posttranscriptional gene regulation. Hepatitis B virus (HBV) causes various liver diseases, including chronic hepatitis, liver cirrhosis and hepatocellular cancer. Recent data have indicated HBV alters miRNAs expression patterns, bu...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2286-x
更新日期：2015-03-01 00:00:00
abstract：:Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alphaherpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neurotropic, they differ...
journal_title：Archives of virology
pub_type： 杂志文章,评审
doi：10.1007/s00705-019-04494-5
更新日期：2020-02-01 00:00:00
abstract：:Recently, a novel reassortant virus, influenza A(H3N2)v [A(H3N2)v], was identified as the causative pathogen in 307 human cases of influenza in the United States. A(H3N2)v contains the matrix gene from the 2009 pandemic H1N1 (pH1N1) virus, while its other genes originate from H3N2 viruses with triple-reassorted intern...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1571-9
更新日期：2013-11-01 00:00:00
abstract：:Bovine leukemia virus (BLV) causes enzootic bovine leucosis (EBL) and is responsible for substantial economic losses in cattle globally. However, information in Africa on the disease is limited. Here, based on clinical, hematological, pathological and molecular analyses, two clinical cases of EBL were confirmed in a d...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3205-0
更新日期：2017-04-01 00:00:00
abstract：:Cocksfoot mottle sobemovirus (CfMV) has a monopartite single-stranded positive-sense RNA genome. In wheat germ extract, in vitro translation of CfMV virion RNA resulted in the production of four major proteins of 100, 71, 34 and 12 kDa. In this paper we show the individual genes from which these polypeptides are synth...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050610
更新日期：1999-01-01 00:00:00
abstract：:Changes in the NP gene of H5N1 highly pathogenic avian influenza (HPAI) viruses have previously been shown to affect viral replication, alter host gene expression levels and affect mean death times in infected chickens. Five amino acids at positions 22, 184, 400, 406, and 423 were different between the two recombinant...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-009-0399-4
更新日期：2009-01-01 00:00:00
abstract：:Although viral protein 3 (VP3) of chicken anaemia virus (CAV) has been well recognised as an inducer of apoptosis, viral protein 2 (VP2) of the virus has only been speculated to have apoptotic activity. This has not been verified because the open reading frame (ORF) encoding VP2 completely encompasses that encoding VP...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2542-8
更新日期：2015-10-01 00:00:00
abstract：:A comparison of 15 field isolates of grapevine leafroll-associated virus 5 (GLRaV-5) was conducted, based on the analysis of nucleotide sequences of two viral ORFs: the coat protein (CP) and the heat shock protein 90 homolog (HSP90h). After amplification and cloning, the population of viral sequences was analyzed for ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1371-2
更新日期：2012-09-01 00:00:00
abstract：:The recent H5N1 avian influenza outbreaks in Asia spread over more than 8 countries. It has caused enormous economic loss and grand challenges for the public health. During these breakouts we isolated three strains of H5N1 Avian Influenza Virus (AIV) from chickens and one from duck in different farms of Southern China...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-004-0474-9
更新日期：2005-06-01 00:00:00
abstract：:During infection host histo-blood group antigens (HBGAs) act as attachment factors that interact with rabbit hemorrhagic disease virus (RHDV) and participate in the infectious process. In the present study, baculovirus expressing recombinant RHDV capsid protein (VP60r) as a vaccine immunogen was used to test its antig...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3509-8
更新日期：2017-11-01 00:00:00
abstract：:The complete bipartite genome (RNA1 and RNA2) of a new nepovirus infecting potato was obtained using small RNA sequencing and assembly complemented by Sanger sequencing. Each RNA encodes a single polyprotein, flanked by 5' and 3' untranslate regions (UTR) and followed by a poly (A) tail. The putative polyproteins enco...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3147-6
更新日期：2017-03-01 00:00:00
abstract：:Oxidative stress is the process by which reactive molecules and free radicals are formed in cells. In this study, we report the blood-based gene expression profile of oxidative stress and antioxidant genes for identifying surrogate markers of liver tissue in chronic hepatitis C (CHC) patients by using real-time PCR. A...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04564-z
更新日期：2020-04-01 00:00:00
