Distinctive features of bovine alphaherpesvirus types 1 and 5 and the virus-host interactions that might influence clinical outcomes.

Abstract:

:Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alphaherpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neurotropic, they differ in their neuropathogenic potential. This review summarizes the findings on the specific mechanisms and pathways known to modulate the pathogenesis of BoHV-1 and BoHV-5, particularly in relation to respiratory and neurological syndromes, which characterize BoHV-1 and BoHV-5 infections, respectively.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Marin M,Burucúa M,Rensetti D,Rosales JJ,Odeón A,Pérez S

doi

10.1007/s00705-019-04494-5

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

285-301

issue

2

eissn

0304-8608

issn

1432-8798

pii

10.1007/s00705-019-04494-5

journal_volume

165

pub_type

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