Abstract：
:The effects of systemic hypothermia (33.5 degrees C) on the ischemia-evoked release of the neurotransmitter amino acids, glutamate, aspartate, gamma-amino-butyric acid (GABA) and glycine into rat cerebral cortical superfusates were evaluated in the rat four vessel occlusion model. Glutamate, aspartate and GABA, but not glycine, levels were enhanced during and following a 20 min period of ischemia. However, when compared with normothermic ischemic animals, no reductions in glutamate, aspartate or GABA levels in the superfusates were apparent either prior to, during or following forebrain ischemic episodes. Indeed, the superfusate levels of aspartate and GABA were transiently increased immediately following ischemia. Glycine levels were significantly depressed, both pre- and post-ischemia, in cortical superfusates from hypothermic animals in comparison with normothermic rats.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Simpson RE,Walter GA,Phillis JWdoi
10.1016/0304-3940(91)90827-gsubject
Has Abstractpub_date
1991-03-11 00:00:00pages
83-6issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(91)90827-Gjournal_volume
124pub_type
杂志文章abstract：:We studied the effect of synthetic rat alpha-atrial natriuretic polypeptide (1-28) (ANF-(99-126)) and related atrial natriuretic polypeptides on the accumulation of cyclic GMP (cGMP) in isolated rat choroid plexus in vitro, the objective being to determine whether ANF-(99-126) binding sites are physiologically active ...
journal_title：Neuroscience letters
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doi：10.1016/0304-3940(87)90692-6
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journal_title：Neuroscience letters
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更新日期：1998-10-02 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(91)90810-g
更新日期：1991-03-11 00:00:00
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journal_title：Neuroscience letters
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更新日期：2004-07-29 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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更新日期：2016-10-28 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：
更新日期：1996-10-18 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 杂志文章
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更新日期：2009-10-30 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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pub_type： 杂志文章
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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更新日期：1985-03-15 00:00:00
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journal_title：Neuroscience letters
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更新日期：2014-02-21 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
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更新日期：2001-02-16 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(93)90452-q
更新日期：1993-06-25 00:00:00
