Abstract：
:The injection of oxytocin into the third ventricle during suckling in lactating rats not only enhances neurosecretory bursts but also the background activity of oxytocin cells. However, removing the young rats 10 min after the oxytocin injection is immediately followed by a decrease in background activity, while injecting oxytocin alone (i.e. without suckling) or suckling alone (i.e. without oxytocin injection) has no effect. These results, which show that the facilitatory effect of oxytocin on oxytocin cell background activity is suckling-dependent, suggest that oxytocin could act either on the afferent pathways for milk ejection or on oxytocin cells themselves, but only if they received inputs from mammary glands. Various hypotheses on the site and mode of action of oxytocin are discussed.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Meyer C,Freund-Mercier MJ,Richard Pdoi
10.1016/0304-3940(87)90079-6subject
Has Abstractpub_date
1987-03-20 00:00:00pages
80-4issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(87)90079-6journal_volume
75pub_type
杂志文章abstract：:myo-Inositol monophosphatase (E.C.3.1.3.25) catalyzes the hydrolysis of myo-inositol 1-phosphate in the presence of Mg2+ at a physiologic pH to form free myo-inositol, maintaining a supply that represents the precursor for inositol phospholipid second messenger signaling systems. In the present study the activity and ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(98)00209-2
更新日期：1998-04-10 00:00:00
abstract：:Several genes expressed in the suprachiasmatic nucleus (SCN) are induced by light and are candidate links in the photic entrainment pathway of the SCN's circadian clock. Since the cAMP response element binding protein (CREB) and CRE-mediated gene transcription in the SCN appears to be crucial for light-induced phase s...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2005.05.018
更新日期：2005-09-02 00:00:00
abstract：:Cutaneous Meissner corpuscles depend for development and survival exclusively on the NT system TrkB/BDNF/NT-4 unlike other types of sensory corpuscles and nerve endings, which have very complex neuronal and growth factor dependence. However, the pattern of expression of TrkB in human Meissner corpuscles is not known. ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2009.10.076
更新日期：2010-01-04 00:00:00
abstract：:Alpha-2 macroglobulin (A2M) is a component of Lewy bodies, a hallmark of Parkinson's disease (PD). In 159 PD patients and 190 normal controls, we studied two A2M polymorphisms by the polymerase chain reaction-restriction fragment length polymorphism method: a five-nucleotide deletion at the 5' splice site of exon 18; ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(02)00003-4
更新日期：2002-08-02 00:00:00
abstract：:The retrofacial nucleus project bilaterally to the ventrolateral nucleus of the tractus solitarius (vlNTS) as revealed by means of retrograde transport of the fluorescent markers, Fast blue (FB) and Diamidino yellow (DY), in the cat. Some of the neurons of the retrofacial nucleus send axonal ramifications to both vlNT...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(87)90415-0
更新日期：1987-05-19 00:00:00
abstract：:The present study has employed in vitro autoradiography to study the distribution and density of [3H]zolpidem binding sites, which are regarded as an index of ethanol-sensitive gamma-aminobutyric acid (GABA)A receptors, in the brains of alcohol-preferring Fawn-Hooded (FH) rats compared to non-alcohol preferring Wistar...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(97)00867-7
更新日期：1997-12-05 00:00:00
abstract：:Alpha-synuclein has been implicated in the pathology of certain neurodegenerative diseases, including Parkinson disease (PD) and dementia with Lewy bodies (LBs). Overexpression of human alpha-synuclein in neuronal cells reduces cell viability, but the precise cellular and molecular mechanisms remain poorly understood....
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2007.02.025
更新日期：2007-04-18 00:00:00
abstract：:In mammals, methyl-CpG binding proteins play a significant role in the control of gene expression through their association with chromatin-remodeling complexes. Mutations in the gene coding for methyl-CpG-binding protein 2 (MECP2) cause Rett syndrome and have also been reported in a number of X-linked mental retardati...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2004.12.036
更新日期：2005-04-29 00:00:00
abstract：:In freshly dissociated viable cells of early postnatal mouse cerebellum, O1 antigen-positive oligodendrocytes have been eliminated by complement dependent immunocytolysis. Before seeding residual cells in culture, O4 antigen-positive cells were immunolabeled by O4 antibody which had been directly conjugated with rhoda...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(82)90351-2
更新日期：1982-04-16 00:00:00
abstract：:In neurodegenerative diseases, such as Alzheimer's disease or HIV encephalitis, neuronal DNA fragmentation has been observed at unexpected high frequencies, without definitive evidence for activation of an irreversible apoptotic pathway. The wobbler mouse is a suggested genetic model of neurodegenerative disease. The ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(01)01741-4
更新日期：2001-06-15 00:00:00
abstract：:The effects of glutamate uptake inhibitors on the L-glutamate-induced increase in intracellular calcium concentrations were assessed in rat primary cortical cultures. The glutamate (10 microM)-induced rise in intracellular calcium concentrations was strongly and dose dependently increased and prolonged by simultaneous...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(95)11395-d
更新日期：1995-03-16 00:00:00
abstract：:The somatosensory system is capable of functional reorganization following peripheral denervation or training. Studies on human amputees with phantom limb pain provided evidence that these reorganizational changes are modulated through nociceptive input. In the present study we used magnetoencephalographic recordings ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(00)01752-3
更新日期：2001-02-09 00:00:00
abstract：:Cerebral ischemia/reperfusion involves inflammatory process and naloxone is able to reduce infarct volume and has been used as a therapeutic agent for brain injury. Hypoxia induces the immediate early genes (IEGs) rapidly and transiently that may initiate a cascade of cellular responses that are necessary for survival...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2008.04.036
更新日期：2008-06-20 00:00:00
abstract：:The non-invasive imaging technique of diffusion tensor imaging (DTI) has been used to investigate the microstructural properties of white matter (WM). The present study investigated whether individual differences in the WM structure of normal subjects as measured by fractional anisotropy (FA) values correlate with cog...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2010.04.031
更新日期：2010-06-21 00:00:00
abstract：:Variation in AKT1 has been associated with schizophrenia, bipolar disease and type II diabetes. The aim of the present study was to investigate the potential role of variability within AKT1 as a risk factor for Parkinson's disease (PD). We performed a case-control association analysis of AKT1 in a Greek cohort of PD u...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2008.03.026
更新日期：2008-05-09 00:00:00
abstract：:Brain content of leucine-enkephalin and methionine-enkephalin changes independently during kindling of the amygdala. Both peptides were measured after 4, 8, 15 and 21 days of stimulation. Leu-enkephalin showed a progressive increase during the kindling: the results on the 4th day did not differ significantly from the ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(81)90337-2
更新日期：1981-10-23 00:00:00
abstract：:Intracellular recordings were made from rat striatal neurones in vitro. In the presence of intracellular caesium and extracellular tetraethylammonium chloride (TEA) (5 mM) and barium (3 mM), long-lasting plateau potentials developed followed by a prominent voltage independent hyperpolarization which lasted several sec...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(87)90384-3
更新日期：1987-08-05 00:00:00
abstract：:Previous research has revealed the existence of perceptual mechanisms that compensate for slight temporal asynchronies between auditory and visual signals. We investigated whether temporal recalibration would also occur between auditory and tactile stimuli. Participants were exposed to streams of brief auditory and ta...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2006.11.027
更新日期：2007-02-08 00:00:00
abstract：:Glufosinate ammonium, a structural analogue of glutamate, is an active herbicidal ingredient. The neuronal activities of this compound were investigated by use of a microdialysis system that allowed us to measure nitric oxide production in the rat cerebellum in vivo. Kainate (0.3-30 nmol/10 microliter), N-methyl-D-asp...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(00)01363-x
更新日期：2000-09-01 00:00:00
abstract：:The action of glycine (Gly) on rat cortical neurons was studied. Gly, iontophoretically applied, hyperpolarized the membrane potential, blocked the firing rate and decreased the amplitude of EPSP-IPSP sequences. Generally the membrane resistance during the aminoacid ejection decreased. The role of Gly in the rat corti...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(79)96085-3
更新日期：1979-05-01 00:00:00
abstract：:Synthetic soluble Aβ oligomers are often used as a surrogate for biologic material in a number of model systems. We compared the activity of Aβ oligomers (synthetic and cell culture media derived) on the human SH-SY5Y neuroblastoma and C2C12 mouse myoblast cell lines in a novel, modified MTT assay. Separating oligomer...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2011.03.082
更新日期：2011-06-15 00:00:00
abstract：:Schisandra chinensis is commonly used for food and as a traditional remedy for the treatment of neuronal disorders. However, it is unclear which component of S. chinensis is responsible for its neuropharmacological effects. To answer this question, we isolated α-iso-cubebene, a dibenzocyclooctadiene lignin, from S. ch...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2013.09.053
更新日期：2013-10-25 00:00:00
abstract：:During early postnatal phase, the environment deeply affects developmental trajectories through epigenetic mechanisms that control the levels of key molecules for brain function, such as neurotrophins. Indeed, it has been shown that adverse early experiences induce epigenetic modifications leading to decreased brain d...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2011.03.038
更新日期：2011-05-20 00:00:00
abstract：:An abnormal distribution of phosphorylated neurofilaments is present in some human neurodegenerative disorders including Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis. This study reports the changes of phosphorylated neurofilaments observed in rat spinal cord after intrathecal injection o...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(90)90751-t
更新日期：1990-10-30 00:00:00
abstract：:The effect of a chronic 17 beta-estradiol (10 micrograms, b.i.d.) treatment of 2 weeks to ovariectomized rats was investigated on lateral and medial caudate-putamen dopamine receptors. Dopamine D2 receptors were assayed with [3H]spiperone binding to caudate-putamen homogenates or by autoradiography of forebrain sectio...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(87)90048-6
更新日期：1987-02-10 00:00:00
abstract：:Galanin (GAL) is distributed in sympathetic nerves in the cat, and exogenous GAL inhibits cardiac vagal action and lowers blood pressure in this species. This study on anaesthetised cats compares the effects on cardiac vagal action and blood pressure of human, rat and porcine GAL. Human GAL has only recently been sequ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(92)90659-u
更新日期：1992-02-17 00:00:00
abstract：:We examined the effects of ibotenic acid induced unilateral lesion of the nucleus basalis magnocellularis (nBM) on carbachol- and serotonin-stimulated phosphoinositide (PI) breakdown in miniprisms obtained from rat fronto-parietal cortex 1 week following the lesion. Lesion-side muscarinic and serotoninergic receptor r...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(95)11658-j
更新日期：1995-06-23 00:00:00
abstract：:By means of a new photographic method to quantitate catecholamine fluorescence in tissue sections it has been possible to demonstrate a high dopamine (DA) turnover within the DA cell bodies of the midbrain. The medially located small-sized DA cell bodies of the A10 DA cell group has a very high DA turnover which was s...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(80)90211-6
更新日期：1980-05-15 00:00:00
abstract：:Daily administration of clonidine for 5 weeks (approx. 300 micrograms/kg/day, p.o.) produced significant decreases in blood pressure and renal sympathetic efferent activity in spontaneously hypertensive rats (SHR). After cessation of clonidine administration, blood pressure and sympathetic nerve activity recovered rap...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(79)96121-4
更新日期：1979-12-01 00:00:00
abstract：:Agmatine (decarboxylated arginine) has been proposed as an endogenous ligand for non-adrenoceptor, imidazoline binding sites, but also binds to alpha 2-adrenoceptors. The interaction of agmatine with alpha 2-adrenoceptors was evaluated by studying the effect of agmatine on the firing rate of locus coeruleus (LC) neuro...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(96)13180-3
更新日期：1996-11-22 00:00:00
