Infection, autoimmunity, and glycolipids: T cells detect microbes through self-recognition.

Abstract:

:De Libero et al. (2005) demonstrate in this issue of Immunity that bacterial infection leads to increased synthesis of autologous glycolipids that are recognized by CD1-restricted human T cells, indicating that recognition of inducible self-glycolipids could be a mechanism for microbial detection. This mechanism also may provide a connection between infection and autoimmunity.

journal_name

Immunity

journal_title

Immunity

authors

Kronenberg M,Kinjo Y

doi

10.1016/j.immuni.2005.06.001

keywords:

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

657-9

issue

6

eissn

1074-7613

issn

1097-4180

pii

S1074-7613(05)00166-4

journal_volume

22

pub_type

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