Abstract:
:The amino acid sequence of ubiquitin from Entamoeba histolytica, as deduced from a cDNA nucleotide sequence, deviated at six positions from the consensus of all other known ubiquitins (ranging from Trypanosoma cruzi to Homo sapiens). The corresponding residues were scattered over the primary sequence, but came close together on the surface of the folded protein structure. We conclude that (i) E. histolytica branched off very early from the main eukaryotic line, and (ii) this organism may yield clues as to the evolutionary development of the ubiquitin system.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Wöstmann C,Tannich E,Bakker-Grunwald Tdoi
10.1016/0014-5793(92)81049-rkeywords:
subject
Has Abstractpub_date
1992-08-10 00:00:00pages
54-8issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(92)81049-Rjournal_volume
308pub_type
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