Femoral osteomyelitis due to Aspergillus nidulans in a patient with chronic granulomatous disease.

Abstract:

:13 cases of osteomyelitis caused by Aspergillus nidulans have been previously reported in patients with chronic granulomatous disease (CGD). All of them have been associated with simultaneous pulmonary infection and have had an extremely poor outcome. We report an unusual case of femoral osteomyelitis due to A. nidulans in a 16-year-old male with CGD, without pulmonary involvement. Treatment with liposomal amphotericin B and granulocyte colony-stimulating factor as well as extensive surgical debridement followed by prolonged treatment with itraconazole resulted in an excellent clinical response.

journal_name

Infection

journal_title

Infection

authors

Dotis J,Panagopoulou P,Filioti J,Winn R,Toptsis C,Panteliadis C,Roilides E

doi

10.1007/s15010-002-2167-1

keywords:

subject

Has Abstract

pub_date

2003-03-01 00:00:00

pages

121-4

issue

2

eissn

0300-8126

issn

1439-0973

journal_volume

31

pub_type

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