Abstract:
:The aminoglycosides play a central role in the treatment of infectious diseases caused by gram-negative bacteria. During the period of January to June 1984, 45 clinical specimens collected in our neonatal intensive care unit grew Enterobacter cloacae; 41 of them were gentamicin resistant. One neonate developed septicemia. The routine antibiotic protocol was then changed from gentamicin-ampicillin to amikacin-ampicillin for a period of six months. During this period the resistance to gentamicin declined to a minimum. Only eight of 122 specimens proved to harbor gram-negative organisms resistant to gentamicin. The gentamicin-resistant E. cloacae vanished. No isolate was resistant to amikacin. The gentamicin-ampicillin regimen was then reintroduced.
journal_name
Infectionjournal_title
Infectionauthors
Raz R,Sharir R,Shmilowitz L,Kenes I,Ephros Mdoi
10.1007/BF01646115subject
Has Abstractpub_date
1987-01-01 00:00:00pages
32-4issue
1eissn
0300-8126issn
1439-0973journal_volume
15pub_type
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