Benefit and advantage to clinicians of a computer-assisted microbiological diagnosis and database system.

Abstract:

:Computer-assisted diagnostic systems may accelerate transmission of microbiological reports and facilitate evaluation of the epidemiological situation and thus improve the collaboration between microbiologists and clinicians. This possible benefit is demonstrated by four examples. It became evident that incidences of pathogens in urinary tract and respiratory tract infections varied within a great range, depending on patient groups and clinical departments involved. Even within a department, different incidences of penicillin G and oxacillin-resistant coagulase-negative staphylococci were demonstrated. An apparent homogeneity of distribution of pathogenic bacteria in a hospital tends to be the result of a nondiscriminating overall evaluation, thus necessarily misleading the clinician especially in empirical chemotherapy. In the last example the evaluation of susceptibility testing revealed changing patterns of some pathogens during the observation period. By rapid exchange of data between the laboratories and the clinical departments supplying the clinicians with information relevant for actual therapeutical decisions, an empiric therapy may change into a so-called calculated therapy based upon data directly related to the site of infection, department and susceptibility patterns.

journal_name

Infection

journal_title

Infection

authors

Manncke K,Heizmann W

doi

10.1007/BF01646938

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

75-80

issue

1

eissn

0300-8126

issn

1439-0973

journal_volume

16

pub_type

杂志文章
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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-007-6273-y

    authors: Hansen D,Patzke PI,Werfel U,Benner D,Brauksiepe A,Popp W

    更新日期:2007-06-01 00:00:00

  • Thrombotic microangiopathies and HIV infection: report of two typical cases, features of HUS and TTP, and review of the literature.

    abstract::Haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are thrombotic microangiopathies increasingly reported in patients with HIV infection. However, characteristic features of thrombotic microangiopathies associated with HIV disease have not been defined yet. The typical courses of HUS and T...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF02565164

    authors: Sutor GC,Schmidt RE,Albrecht H

    更新日期:1999-01-01 00:00:00

  • Optimal duration of antimicrobial therapy for uncomplicated Gram-negative bloodstream infections.

    abstract:PURPOSE:Optimal antimicrobial treatment duration for Gram-negative bloodstream infection (BSI) remains unclear. This retrospective cohort study examined effectiveness of short (7-10 days) and long (>10 days) courses of antimicrobial therapy for uncomplicated Gram-negative BSI. METHODS:Hospitalized adults with uncompli...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-017-1020-5

    authors: Nelson AN,Justo JA,Bookstaver PB,Kohn J,Albrecht H,Al-Hasan MN

    更新日期:2017-10-01 00:00:00

  • IFN-alpha: therapeutic options in HIV and HIV/HCV, HIV/HBV dual infection.

    abstract::The antiviral effects of interferon-alpha (IFN-alpha) are well documented for the treatment of hepatitis B or C infections, whereas antiretroviral effects for treatment of HIV-1 infection have been investigated up to now only in small-sized preclinical studies. New preclinical and clinical data on IFN-alpha for HIV, H...

    journal_title:Infection

    pub_type:

    doi:

    authors: Jablonowski H

    更新日期:2003-03-01 00:00:00

  • In-vitro activity of lomefloxacin (SC-47111) and other quinolones.

    abstract::The in vitro activity of lomefloxacin, a new difluorinated quinolone, was compared to that of ciprofloxacin, ofloxacin, norfloxacin and other relevant antibacterial agents. Lomefloxacin and norfloxacin shared similar activity, whereas ofloxacin and in particular ciprofloxacin showed superior activity. Most gram-negati...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644019

    authors: Sun ZM,Maskell JP,Sehgal SC,Williams JD

    更新日期:1989-05-01 00:00:00

  • Family outbreak of an infection with a recombinant Coxsackie A virus in eastern Switzerland.

    abstract:PURPOSE:We report on an unusual familial outbreak of a coxsackie virus infection in Switzerland in which five family members were affected. Most of the patients presented with signs of meningitis, and four were hospitalized. METHODS:In three individuals, the virus was detected in the cerebrospinal fluid, pharynx, and ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-012-0340-8

    authors: Butsch R,Tapparel C,Keller P,Herzog K,Krause M,Wunderli W,Kaiser L,Bossart W

    更新日期:2013-02-01 00:00:00

  • Analysis of the specific immune response against capsular polysaccharides of two patients with systemic enterococcal infections.

    abstract::Systemic enterococcal infections often lead to life-threatening disease. By analyzing the immune response of two patients with systemic enterococcal infections against enterococcal polysaccharide antigens, we found that both patients had antibodies against all four of the capsular serotypes identified to date. Antibod...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-005-5062-8

    authors: Hufnagel M,Huebner J

    更新日期:2005-10-01 00:00:00

  • Chlamydia trachomatis: serological diagnosis.

    abstract::Satisfactory methods for the serodiagnosis of Chlamydia trachomatis have been widely discussed in recent years. Until a decade ago, the complement-fixation test measuring group-specific antibody was the most widely applied technique. However, despite showing relatively high diagnostic sensitivity in systemic chlamydia...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01640711

    authors: Treharne JD

    更新日期:1982-01-01 00:00:00

  • Quantitative antibiotic use in hospitals: comparison of measurements, literature review, and recommendations for a standard of reporting.

    abstract:BACKGROUND:Reports on antibiotic use often lack complete definitions of the units of measurement, hampering the comparison of data between hospitals or hospital units. PATIENTS AND METHODS:To compare methods of measures of in-hospital antimicrobial use, we determined aggregate in-hospital consumption data at a tertiar...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-008-7462-z

    authors: Kuster SP,Ruef C,Ledergerber B,Hintermann A,Deplazes C,Neuber L,Weber R

    更新日期:2008-12-01 00:00:00

  • Hospital at home for the management of COVID-19: preliminary experience with 63 patients.

    abstract::Alternatives to conventional hospitalization are needed to increase health systems resilience in the face of COVID-19 pandemic. Herein, we describe the characteristics and outcomes of 63 patients admitted to a single HaH during the peak of COVID-19 in Barcelona. Our results suggest that HaH seems to be a safe and effi...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-020-01527-z

    authors: Pericàs JM,Cucchiari D,Torrallardona-Murphy O,Calvo J,Serralabós J,Alvés E,Agelet A,Hidalgo J,Alves E,Castells E,Seijas N,Hernández C,Bodro M,Cardozo C,Coloma E,Nicolás D,Hospital Clínic 4H Team (Hospital at Home-Health H

    更新日期:2020-09-29 00:00:00

  • Prophylactic chemotherapy with fosfomycin trometamol during transurethral surgery and urological manoeuvres. Results of a multicentre study.

    abstract::The aim of the present open prospective study is to evaluate the efficacy and safety profile of fosfomycin trometamol in the chemoprophylaxis of urinary tract infections following transurethral diagnostic and/or therapeutic manoeuvres. 712 patients were enrolled in 72 urological surgical centres. All the enrolled pati...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1007/BF01643436

    authors: di Silverio F,Ferrone G,Carati L

    更新日期:1990-01-01 00:00:00

  • Infections in intraabdominal surgery. The EURESI Project. European Research Network on Surgical Infections.

    abstract::The situation of clinical research in Europe must be improved substantially according to statements of scientists, managers and politicians. The analysis of requirements is available; however, there are no indications that the conclusion of the analysis is being converted into actual facts. Government programs, althou...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF02962265

    authors: Holzheimer RG

    更新日期:1998-09-01 00:00:00

  • Immunoglobulin prophylaxis against hepatitis A among Swedish UN soldiers in an endemic region.

    abstract::Six hundred and fifteen Swedish soldiers (X = 24.9 years) serving with the UN forces in Cyprus were tested for antibody against hepatitis A (anti-HAV) before and after six months' service. Before the service, a high susceptibility to hepatitis A was found, as only 2.3% (14/615) had anti-HAV. In comparison, the prevale...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01648930

    authors: Weiland O,Berg JV,Bäck E,Lundbergh P

    更新日期:1979-01-01 00:00:00

  • Pharmacokinetics of ampicillin, sulbactam and cefotiam in patients undergoing orthopedic surgery.

    abstract::As perioperative prophylaxis for major orthopedic operations 81 patients were given the fixed combination of ampicillin (1 g)/sulbactam (0.5 g) or cefotiam (2 g) as short infusions. The three beta-lactams were rapidly distributed into the different tissues and their pharmacokinetic profiles were found to be very simil...

    journal_title:Infection

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF01713160

    authors: Wildfeuer A,Mallwitz J,Gotthardt H,Hille E,Gruber H,Dahmen G,Pfaff G,Göbel C

    更新日期:1997-07-01 00:00:00

  • Ciprofloxacin concentrations in tonsils following a single intravenous infusion.

    abstract::Penetration of ciprofloxacin into human tonsils was studied following an intravenous infusion of 200 mg over 15 minutes to adult humans undergoing tonsillectomy. Samples were taken one-and-a-half to four hours after dosing. Generally, tissue levels exceeded corresponding serum concentrations by 50% (range of intraindi...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01651152

    authors: Falser N,Dalhoff A,Weuta H

    更新日期:1984-09-01 00:00:00

  • Serological biomarkers of candidemia: a retrospective evaluation of three assays.

    abstract:PURPOSE:Serologic testing allows for rapid detection of candidemia. More data are needed for the Virion\Serion ELISA antigen test (Ag), Hemkit Candida IHA antibody test (Ab), and Wako β-1,3-D-glucan assay (BDG). METHODS:Tests were performed on serum samples from 120 cases of culture-confirmed candidemia and 44 Candida...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-018-1224-3

    authors: Dichtl K,Seybold U,Wagener J

    更新日期:2019-04-01 00:00:00

  • Comparison in a laboratory model between the performance of a urinary closed system bag with double non-return valve and that of a single valve system.

    abstract:BACKGROUND:Catheter-associated urinary tract infection is the most common nosocomial infection in clinical settings. For bacteria ascending to the bladder the most common route is the extraluminal, but the intraluminal route also plays a role. For this reason, we compared two urinary closed system bags (CSB), one with ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-006-5626-2

    authors: Wenzler-Röttele S,Dettenkofer M,Schmidt-Eisenlohr E,Gregersen A,Schulte-Mönting J,Tvede M

    更新日期:2006-08-01 00:00:00

  • The pharmacokinetics of trimethoprim and trimethoprim/sulphonamide combinations, including penetration into body tissues.

    abstract::In this review the pharmacokinetic properties of trimethoprim (TMP) and TMP/sulphonamide combinations are discussed. The concentration of both substances in the various body fluids and tissues differ considerably from the concentrations in blood due to the different distribution of TMP and sulphonamides in the body. A...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01639009

    authors: Reeves DS,Wilkinson PJ

    更新日期:1979-01-01 00:00:00

  • [In vitro effect of acylureido penicillins and mezlocillin on anaerobic sporeless gram-negative rods of genus Bacteroides].

    abstract::313 anaerobic gram-negative rods of the Bacteroides genus isolated from 295 clinical specimens were tested for their sensitivity to azlocillin and mezlocillin using the dilution method with agar plates. 25 mg/l of azlocillin inhibited 80.2% of the strains and the same concentration of mezlocillin inhibited 86.9%. The ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01640681

    authors: Höhne C

    更新日期:1982-01-01 00:00:00

  • Lymphocyte apoptosis, caspase activation and inflammatory response in septic shock.

    abstract:BACKGROUND:We examined lymphocyte apoptosis, activity of caspases-1, -3, -8 and -9 and the relationship between those two events and inflammation response in septic shock. MATERIALS AND METHODS:Blood samples were obtained within 24 h after diagnosis of septic shock from 16 patients to measure apoptosis, caspases-3, -8...

    journal_title:Infection

    pub_type: 信件

    doi:10.1007/s15010-008-7070-y

    authors: Delogu G,Famularo G,Tellan G,Marandola M,Antonucci A,Signore M,Marcellini S,Moretti S

    更新日期:2008-10-01 00:00:00

  • Candidemia in intensive care unit patients: risk factors for mortality.

    abstract::Aim of this study was to evaluate whether risk factors which predict the development of candidemia may also predict death in ICU patients with candidemia. During an 8-year-period all ICU patients whose blood cultures yielded Candida species (n = 40) were retrospectively evaluated in a case-control fashion. The average...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF02113499

    authors: Voss A,le Noble JL,Verduyn Lunel FM,Foudraine NA,Meis JF

    更新日期:1997-01-01 00:00:00

  • Urine bactericidal activity of pefloxacin versus norfloxacin in healthy female volunteers after a single 800-mg oral dose.

    abstract::In an open randomised crossover study the antibacterial activity of pefloxacin and norfloxacin was assessed in the urine after a single 800-mg oral dose in 14 healthy female volunteers. Pefloxacin demonstrated lower peak concentrations in the urine than norfloxacin (mean, 217.2 mg/l versus 492.9 mg/l as determined by ...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF02113592

    authors: Hofbauer H,Naber KG,Kinzig-Schippers M,Sörgel F,Rustige-Wiedemann C,Wiedemann B,Reiz A,Kresken M

    更新日期:1997-03-01 00:00:00

  • Reactivation of hepatitis C virus superinfection in a patient seropositive for hepatitis B e antigen.

    abstract::During the course of chronic hepatitis B virus (HBV) infection, a patient seropositive for hepatitis B e antigen experienced four episodes of acute hepatic necroinflammation. Serum HBV-DNA concentration elevated immediately before the first and third exacerbations, whereas serum hepatitis C virus (HCV) RNA was detecte...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-001-1195-6

    authors: Chen LW,Yeh CT,Fang KM,Chu CM,Liaw YF

    更新日期:2001-12-01 00:00:00

  • Transitory ventricular tachycardia associated with influenza A infection of cardiac conduction tissue.

    abstract:PURPOSE:To describe the influence of cardiac conduction tissue infection by Influenza A virus. METHODS AND RESULTS:A 54-year-old man with non-sustained ventricular tachycardia underwent noninvasive and invasive cardiac studies including left ventricular endomyocardial biopsy (LVEMB). Non-invasive studies showed normal...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-016-0892-0

    authors: Frustaci A,Petrosillo N,Ippolito G,Chimenti C

    更新日期:2016-06-01 00:00:00

  • Pneumopericardium complicating invasive pulmonary aspergillosis: case report and review.

    abstract::Pneumopericardium, the presence of air in the pericardial space, is a rare disorder that is usually caused by trauma. We describe a patient given induction chemotherapy for acute myelogenous leukemia who developed pulmonary aspergillosis that resulted in pericarditis and pneumopericardium. He responded to antifungal t...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01739015

    authors: van Ede AE,Meis JF,Koot RA,Heystraten FM,de Pauw BE

    更新日期:1994-03-01 00:00:00

  • Infection in immunodepressed patients. The approach to diagnosis and treatment.

    abstract::Infection is an important cause of death in patients receiving cytostatic drugs or with any other impairment of host resistance. Such infections are frequently due to opportunist micro-organisms usually belonging to the endogenous flora of the patient. It is often difficult to obtain an exact diagnosis of the cause an...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01642766

    authors: Nauta EH,van Furth R

    更新日期:1975-01-01 00:00:00

  • [Erythromycin determination in organ tissues (author's transl)].

    abstract::The recovery rates of erythromycin after in vitro and in vivo administration were studied comparatively in liver, lung, and kidney. Using buffer standards the recovery rate in homogenates of in vitro administered erythromycin decreased with increasing protein concentration. At constant protein concentration the erythr...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641124

    authors: Dette GA,Finke U

    更新日期:1979-01-01 00:00:00

  • [Use and risk of antibacterial chemotherapy from the medical point of view].

    abstract::The evaluation of the efficacy and possible intolerance of an antibacterial chemotherapy is based on the exact analysis of patient specific signs and symptoms, pathogenetic factors of the specific bacteria and parameters of the specific substance. One has to differentiate between usefulness of the antibiotics (effect)...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644740

    authors: Lode H

    更新日期:1991-01-01 00:00:00

  • Chlamydia trachomatis in andrologic patients--direct and indirect detection.

    abstract:BACKGROUND:Chlamydia trachomatis is considered to be the most common sexually transmitted disease in Germany. It is currently unclear whether chlamydial infection causes pathological conditions of the male accessory glands with consequences for male infertility. PATIENTS AND METHODS:Within the framework of several pro...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-001-0088-z

    authors: Bollmann R,Engel S,Petzoldt R,Göbel UB

    更新日期:2001-05-01 00:00:00

  • Influence of intimal Chlamydophila pneumoniae persistence on cardiovascular complications after coronary intervention.

    abstract:PURPOSE:Chlamydophila pneumoniae has been implicated in atherosclerosis/restenosis; however, clear evidence is missing. Therefore, the aim of our study was to examine the influence of intimal infection and systemic inflammation on cardiovascular complications after coronary intervention. METHODS:45 atheroma specimens ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-014-0694-1

    authors: Tuleta I,Reek D,Braun P,Bauriedel G,Nickenig G,Skowasch D,Andrié R

    更新日期:2015-02-01 00:00:00