Abstract:
:Infection is an important cause of death in patients receiving cytostatic drugs or with any other impairment of host resistance. Such infections are frequently due to opportunist micro-organisms usually belonging to the endogenous flora of the patient. It is often difficult to obtain an exact diagnosis of the cause and localization of the infection. The problems associated with the prevention of infection are manifold. Exogenous infections can be prevented by proper isolation and a sterile diet. Endogenous infections can only be prevented by eradication of the patient's endogeous flora, so-called decontamination. Special attention should be given to treatment of foci of chronic infection and of the carrier state of certain microorganisms. However, the prophylactic use of antibiotics should be avoided. The curative use of antibiotics should be based on the most probable micro-organism. We consider the inventory of the patient's microflora, repeated weekly, of great help in the choice of antibiotics in cases of septicaemia of unknown aetiology. The initial therapy usually consists of a broad-spectrum combination of antibiotics, which should be bactericidal. When the causative bacteria have been isolated and the sensitivity is known, antibiotic therapy should be adjusted to the narrowest spectrum possible.
journal_name
Infectionjournal_title
Infectionauthors
Nauta EH,van Furth Rdoi
10.1007/BF01642766subject
Has Abstractpub_date
1975-01-01 00:00:00pages
202-8issue
4eissn
0300-8126issn
1439-0973journal_volume
3pub_type
杂志文章相关文献
INFECTION文献大全abstract::Twenty-eight patients who underwent open-heart surgery were divided into three groups, each of which received a different antibiotic from the cephalosporin series (cephalotin, cefazolin or cefamandole) in order to prevent infection. All antibiotics were given via intravenous infusion in a dosage of 2 g prior to surger...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01641087
更新日期:1978-01-01 00:00:00
abstract::The concentrations of ciprofloxacin produced in bone, cartilage and menisci after a single administration of 200 mg were determined at different intervals in a group of patients with an average age of 80 years. Concentrations of 0.11 to 0.94 mg/kg bone tissue were measured after 0.5 to 5 hours. In the cartilage a conc...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01642108
更新日期:1990-05-01 00:00:00
abstract::Erythromycin ethylsuccinate was given orally (30-60 mg/kg/day) to 72 otherwise healthy children for different intervals before adenoidectomy. The concentration of erythromycin was assessed in homogenized tissue, in whole blood and in plasma, making it possible to calculate blood-free tissue levels. The tissue levels (...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01640866
更新日期:1982-01-01 00:00:00
abstract::The original version of this article unfortunately contained a mistake. In the author list, the first and last names were tagged incorrectly. The corrected author list is given above. ...
journal_title:Infection
pub_type: 已发布勘误
doi:10.1007/s15010-020-01490-9
更新日期:2020-10-01 00:00:00
abstract::The original version of this article unfortunately contained a mistake. ...
journal_title:Infection
pub_type: 已发布勘误
doi:10.1007/s15010-020-01465-w
更新日期:2020-08-01 00:00:00
abstract::The penicillins, the tetracyclines and the sulfonamides have often been used in the last few decades in spite of their well-known side effects. Hypersensitivity reactions to penicillins are among the most important adverse reactions in these antibiotics; in every case a careful medical history has to be taken before a...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/BF01644730
更新日期:1991-01-01 00:00:00
abstract::Polymorphonuclear leukocyte (PMNL) chemotaxis was evaluated in ten healthy volunteers who had received 600 mg of clindamycin intramuscularly. Serum obtained 3 hours after the administration of clindamycin significantly increased PMNL chemotaxis. Serum obtained at 12 and 24 hours after the administration of the drug di...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01712455
更新日期:1993-09-01 00:00:00
abstract::The concentration of imipenem in organic bone, determined in 16 patients by bioassay after short infusion (15 min) of 1 g imipenem/cilastatin was 4.3 +/- 2.06 mg/kg (geometric mean +/- standard deviation, n = 13) after 45 minutes, and 2.8 +/- 1.86 mg/kg (n = 26) after 88 minutes. Imipenem penetrates into inorganic hyd...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01647497
更新日期:1986-01-01 00:00:00
abstract::Antibiotic activity against common respiratory pathogens can be affected by the pH of the medium (in vitro) or the bodily fluid (in vivo) in which bacteria are present. The ionized fraction of an antibiotic is not able to efficiently penetrate bacterial or mammalian membranes, reducing the quantity of molecules able t...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-005-8206-y
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:To evaluate the impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional approach on the reduction of ventilator-associated pneumonia (VAP) in adult patients hospitalized in 11 intensive care units (ICUs), from 10 hospitals, members of the INICC, in 10 cities of Turkey. METH...
journal_title:Infection
pub_type: 杂志文章,多中心研究
doi:10.1007/s15010-013-0407-1
更新日期:2013-04-01 00:00:00
abstract::Intestinal infection by Escherichia coli O157 and other verotoxin (VT) producing E. coli has been increasingly recognized as an important factor for the causation of classic (enteropathic) hemolytic uremic syndrome (HUS) and hemorrhagic colitis (HC). Toxins most frequently involved are VT1 and VT2. As with other toxin...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01710530
更新日期:1993-05-01 00:00:00
abstract::The in vitro activity of clarithromycin alone and in combination with its primary human metabolite, 14-hydroxy-clarithromycin, was determined against 203 strains of Haemophilus influenzae. Microdilution broth MICs and MBCs of both clarithromycin and 14-hydroxy-clarithromycin were determined. The clarithromycin MIC50 w...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01704612
更新日期:1992-05-01 00:00:00
abstract::Thrombocytosis is rarely observed during infection. We are describing a patient with acute osteomyelitis and bacteremia who developed thrombocytosis. In the patient described the platelet count paralleled the activity of the infection and the response to therapy. The causes of thrombocytosis and its implications are b...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01645220
更新日期:1984-11-01 00:00:00
abstract::Pre-existing occlusion of the inferior vena cava may complicate renal transplantation. Suppurative abdominal wall phlebitis following renal transplantation was diagnosed in a patient with pre-existing thrombosis of the inferior vena cava of unknown cause. The phlebitis developed in the subcutaneous collateral veins of...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-012-0335-5
更新日期:2013-02-01 00:00:00
abstract::From the microbiological point of view a variety of highly active compounds has contributed to improved efficacy of antibacterial chemotherapy during the last few decades. In some cases, however, resistance has increased due to different molecular mechanisms. Resistance to the new generation of broad-spectrum beta-lac...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/BF01644735
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Screening for staphylococci among various patient populations has become important for appropriate therapeutic management and for control of nosocomial infections. The purpose of this study is to evaluate the in vitro sensitivity and specificity of a chromogenic agar medium, S. aureus ID (bioMérieux, France)...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-006-5094-8
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVES:There is increasing evidence indicating an association between invasive non-typeable Haemophilus influenzae (NTHi) infection in pregnancy and early pregnancy loss. As the diagnosis relies on microbiological investigation of post-mortem placental and foetal samples, a significant proportion of NTHi-related pr...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-019-01359-6
更新日期:2020-04-01 00:00:00
abstract::To assess the in vitro activity of cefpodoxime against anaerobic respiratory tract and oropharyngeal pathogens 77 strains belonging to 18 gram-negative and 7 gram-positive species were studied by means of agar dilution tests. For comparison cefuroxime, amoxicillin, amoxicillin + clavulanic acid and clindamycin were al...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01645372
更新日期:1991-09-01 00:00:00
abstract::Haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are thrombotic microangiopathies increasingly reported in patients with HIV infection. However, characteristic features of thrombotic microangiopathies associated with HIV disease have not been defined yet. The typical courses of HUS and T...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/BF02565164
更新日期:1999-01-01 00:00:00
abstract::A case of appendicitis followed by reactive arthritis in an HLA B27-positive, 29-year-old man after infection with Yersinia enterocolitica is reported. Infection with Y. enterocolitica was diagnosed by determination of serotype specific antibodies and antibodies to Yersinia outer membrane proteins. Bacteriological cul...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01720409
更新日期:1997-09-01 00:00:00
abstract::Mycoplasma hominis is a commensal of the genitourinary tract, which is infrequently associated with urogenital infections. Extra-urogenital infections due to M. hominis are rare. Here, we report an unusual case of M. hominis subdural empyema in a woman occurring shortly after delivery. The patient presented with sympt...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-014-0713-2
更新日期:2015-04-01 00:00:00
abstract::The minimum duration of continuous amphotericin B irrigation (50 mg/liter/day) required to clear the candida colonizing the urinary bladder was investigated. Eleven in vitro experiments revealed a consistent candidicidal effect within 48 hours with 25 and 5 mg/l of amphotericin B concentrations attainable in the bladd...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01647004
更新日期:1990-09-01 00:00:00
abstract::Bacterial meningitis of infants and children exact a major toll worldwide. Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis continue to be the major causes, and efforts to reduce the incidence of this disease have had limited success. Major advances in rapid diagnosis, such as antigen detect...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/BF01641744
更新日期:1984-01-01 00:00:00
abstract::In this open study the efficacy and tolerability of rufloxacin in a single dose of 400 mg the first day and 200 mg the nine consecutive days was studied in 26 patients with an acute exacerbation of chronic bronchitis. Twenty-two patients were evaluable for efficacy. Four patients stopped treatment prematurely after fi...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01644971
更新日期:1991-07-01 00:00:00
abstract::Dysbiosis does not necessarily mean disease. Typical clinical picture of disease caused by metabolic activity of dysbiotic microflora is the microbial over-growth syndrome. We studied case histories of 434 patients without consideration of their basic illnesses and correlated them with types of dysbioses of duodenal j...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01639535
更新日期:1989-07-01 00:00:00
abstract::Cefoperazone, an antibiotic commonly used for prophylaxis of infection, has been associated with hypoprothrombinemia and bleeding. To reduce the risk of bleeding, co-administration of vitamin K has been advised. We reassessed the need for vitamin K use in a retrospective analysis of 50 patients undergoing urologic pro...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01704604
更新日期:1992-05-01 00:00:00
abstract:PURPOSE:SARS-CoV-2 is a recently emerged ß-coronavirus. Here we present the current knowledge on its epidemiologic features. METHODS:Non-systematic review. RESULTS:SARS-CoV-2 replicates in the upper and lower respiratory tract. It is mainly transmitted by droplets and aerosols from asymptomatic and symptomatic infect...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-020-01531-3
更新日期:2020-10-08 00:00:00
abstract::The antibiotic most appropriate for prophylaxis of postoperative infections depends on the nature of the operation. In aseptic (clean) operations, gram-positive postoperative infections are the primary concern, and cefazolin is recommended because of its excellent pharmacokinetics and good activity against gram-positi...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/BF01715775
更新日期:1991-01-01 00:00:00
abstract::A 67-year-old patient died of Legionella bozemanii pneumonia with negative urinary antigen and negative serology. Cystic lesions in pneumonia of unknown origin should lead to the differential diagnosis of L. bozemanii infections. ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6251-4
更新日期:2007-06-01 00:00:00
abstract::The original version of this article unfortunately contained a mistake. ...
journal_title:Infection
pub_type: 已发布勘误
doi:10.1007/s15010-020-01463-y
更新日期:2020-08-01 00:00:00