Prophylaxis of postoperative infections.

Abstract:

:The antibiotic most appropriate for prophylaxis of postoperative infections depends on the nature of the operation. In aseptic (clean) operations, gram-positive postoperative infections are the primary concern, and cefazolin is recommended because of its excellent pharmacokinetics and good activity against gram-positive pathogens, including staphylococci. In those operations where violation of the digestive tract creates a contaminated field, a cefotaxime-generation cephalosporin is the agent of choice because of the excellent safety profiles and the capability of agents of this class to kill essentially all pathogenic gram-negative aerobes as well as a substantial portion of anaerobes. Selection of resistant bacteria has not been significant and is unlikely to become so with single-dose prophylaxis. Occasionally, if there is a high probability that the operative field may be heavily contaminated by anaerobes, metronidazole should be added. Dosing should be sufficient to cover the operative period. Only a single prophylactic dose is necessary, given at the time of induction of anesthesia. For particularly long operations, a second dose of those antibiotics with half-lives shorter than 60 min is required two hours after the first. Single-injection prophylaxis is effective, inexpensive, has no side effects and does not induce bacterial resistance.

journal_name

Infection

journal_title

Infection

authors

Wittmann DH,Condon RE

doi

10.1007/BF01715775

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

S337-44

eissn

0300-8126

issn

1439-0973

journal_volume

19 Suppl 6

pub_type

杂志文章,评审
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    pub_type: 杂志文章

    doi:10.1007/BF01659751

    authors: Paul E

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  • [Erythromycin determination in organ tissues (author's transl)].

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641124

    authors: Dette GA,Finke U

    更新日期:1979-01-01 00:00:00

  • [Use and risk of antibacterial chemotherapy from the medical point of view].

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644740

    authors: Lode H

    更新日期:1991-01-01 00:00:00

  • Kinetics and correlation with body temperature of circulating interleukin-6, interleukin-8, tumor necrosis factor alpha and interleukin-1 beta in patients with fever and neutropenia.

    abstract::Interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), interleukin-8 (IL-8) and tumor necrosis factor alpha (TNF) are important mediators of fever and inflammation, and are involved in the pathogenesis of sepsis. There is only limited data on serum concentrations of these proinflammatory cytokines in patients with feve...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01716695

    authors: Engel A,Kern WV,Mürdter G,Kern P

    更新日期:1994-05-01 00:00:00

  • Burrowing bug pigmentation.

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    doi:10.1007/s15010-020-01481-w

    authors: Chakraborty S,Sil A,Panigrahi A

    更新日期:2020-07-11 00:00:00

  • First report of chronic implant-related septic arthritis and osteomyelitis due to Kytococcus schroeteri and a review of human K. schroeteri infections.

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-012-0250-9

    authors: Chan JF,Wong SS,Leung SS,Fan RY,Ngan AH,To KK,Lau SK,Yuen KY,Woo PC

    更新日期:2012-10-01 00:00:00

  • Benefit and advantage to clinicians of a computer-assisted microbiological diagnosis and database system.

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01646938

    authors: Manncke K,Heizmann W

    更新日期:1988-01-01 00:00:00

  • Correction to: Mucormycosis in hospitalized patients at a tertiary care center in Lebanon: a case series.

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    journal_title:Infection

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s15010-018-1203-8

    authors: El Zein S,El-Sheikh J,Zakhem A,Ibrahim D,Bazarbachi A,Kanj SS

    更新日期:2018-12-01 00:00:00

  • Correction to: Clinical management of ageing people living with HIV in Europe: the view of the care providers.

    abstract::The original version of this article unfortunately contained a mistake. ...

    journal_title:Infection

    pub_type: 已发布勘误

    doi:10.1007/s15010-020-01463-y

    authors: Boffito M,Ryom L,Spinner C,Martinez E,Behrens G,Rockstroh J,Hohenauer J,Lacombe K,Psichogyiou M,Voith N,Mallon P,Branco T,Svedhem V,dÁrminio Monforte A

    更新日期:2020-08-01 00:00:00

  • Effective treatment of urinary tract infections.

    abstract::In prescribing any particular antimicrobial agent for the treatment of urinary tract infection decisions have to be made on the choice of drug, on the basis of bacteriological findings, the dosage and the duration of administration. These problems are reviewed below in conjunction with the criteria of successful thera...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644939

    authors: Acar JF

    更新日期:1980-01-01 00:00:00

  • Spontaneous spondylodiscitis caused by Klebsiella pneumoniae.

    abstract::A rare case of spontaneous spondylodiscitis caused by Klebsiella pneumoniae in a 55-year-old man who presented with thoracolumbar pain is described. Increased erythrocyte sedimentation rate and C-reactive protein level were pertinent laboratory findings. Computed tomography revealed a paravertebral mass and destructio...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s150100050046

    authors: Kouroussis C,Georgoulias V,Souglakos J,Simvoulakis E,Karabekios S,Samonis G

    更新日期:1999-11-01 00:00:00

  • Clinical evaluation of the antifungal effect of sertraline in the treatment of cryptococcal meningitis in HIV patients: a single Mexican center experience.

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    journal_title:Infection

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s15010-017-1059-3

    authors: Villanueva-Lozano H,Treviño-Rangel RJ,González GM,Hernández-Rodríguez PA,Camacho-Ortiz A,Castillo-Reyna L,Galindo-Alvarado SG,Martínez-Reséndez MF

    更新日期:2018-02-01 00:00:00

  • Safety and immunogenicity of early vaccination with two doses of tetravalent measles-mumps-rubella-varicella (MMRV) vaccine in healthy children from 9 months of age.

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    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s15010-007-6337-z

    authors: Goh P,Lim FS,Han HH,Willems P

    更新日期:2007-10-01 00:00:00

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    abstract::In a randomized study, 42 patients undergoing extensive maxillo-facial surgery (correction of the position of the mandible or maxilla by using autologous bone transplants) received prophylactically ten-day courses of either flucloxacillin or amoxicillin with clavulanic acid. Patients were comparable with regard to age...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01644122

    authors: Vlaspolder F,de Zeeuw G,Rozenberg-Arska M,Egyedi P,Verhoef J

    更新日期:1987-07-01 00:00:00

  • 'Lost in Nasal Space': Staphylococcus aureus sepsis associated with Nasal Handkerchief Packing.

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-018-1221-6

    authors: Koehler P,Jung N,Kochanek M,Lohneis P,Shimabukuro-Vornhagen A,Böll B

    更新日期:2019-04-01 00:00:00

  • Were all carbapenemases created equal? Treatment of NDM-producing extensively drug-resistant Enterobacteriaceae: a case report and literature review.

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    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-017-1070-8

    authors: Chibabhai V,Nana T,Bosman N,Thomas T,Lowman W

    更新日期:2018-02-01 00:00:00

  • Detection of legionella species in clinical samples: Comparison of polymerase chain reaction and urinary antigen detection kits.

    abstract:BACKGROUND:Recently, two excellent methods have been used for the diagnosis of Legionnaires' disease: urinary antigen detection and PCR. The purpose of the present study is to analyze and evaluate the sensitivity and specificity of three different urinary antigen detection kits as well as PCR. MATERIALS AND METHODS:A ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-006-6639-6

    authors: Koide M,Higa F,Tateyama M,Nakasone I,Yamane N,Fujita J

    更新日期:2006-10-01 00:00:00

  • [Bactericidal activity of enoxacin and ciprofloxacin in body fluids].

    abstract::Until present studies are lacking which investigate the bactericidal activity of new quinolones in body fluids. Therefore, we determined bactericidal titers of enoxacin (en) and ciprofloxacin (cip) against a typical pathogen in urinary tract infections (Escherichia coli) in urine and against a typical pathogen in resp...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01643629

    authors: Roos R,Jäger A,Kraeft H,Adam D

    更新日期:1989-01-01 00:00:00

  • [Pseudomonas aeruginosa immunoglobulin in experimental pneumonia].

    abstract::A guinea pig model of experimental Pseudomonas aeruginosa pneumonia was used to evaluate factors affecting the efficacy of passive immune therapy with Psomaglobin N, a hyperimmune P. aeruginosa globulin. Animals treated 2 h after infection with a single intravenous infusion of Psomaglobin N, 500 mg/kg, demonstrated 33...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644192

    authors: Pennington JE,Pier GB

    更新日期:1987-01-01 00:00:00

  • ELISA for antibodies to lipid A, lipopolysaccharides and other hydrophobic antigens.

    abstract::A simple, sensitive and rapid ELISA method for the quantification and characterization of antibodies to lipid A has been developed, which can also be applied to other hydrophobic antigens. For coating, antigens were applied to the wells of ELISA plates as solutions in a mixture of chloroform and ethanol 1:9 (v/v), and...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01650719

    authors: Freudenberg MA,Fomsgaard A,Mitov I,Galanos C

    更新日期:1989-09-01 00:00:00

  • Clinical features of liver involvement in adult patients with listeriosis. Review of the literature.

    abstract::Clinical features of liver involvement due to Listeria monocytogenes infection in adults are rarely reported in literature. This is surprising, regarding the current opinion that the portal system is extensively involved in the first stages of pathogenesis in invasive L. monocytogenes disease. A literature search in t...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-007-6006-2

    authors: Scholing M,Schneeberger PM,van den Dries P,Drenth JP

    更新日期:2007-06-01 00:00:00

  • Placental Schistosoma haematobium infection in a German returnee from Malawi.

    abstract::Schistosomiasis is a widespread helminthic infection which sometimes may affect travelers to endemic areas. We report on a case of urogenital and placental schistosomiasis in a 28-year-old German woman who had been exposed to schistosomiasis in Lake Malawi one year earlier. She experienced painless macrohaematuria in ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-014-0684-3

    authors: Schleenvoigt BT,Gajda M,Baier M,Groten T,Oppel-Heuchel H,Grimm MO,Pfister W,Richter J,Pletz MW

    更新日期:2014-12-01 00:00:00

  • In vitro activity of new cephalosporins against multi-resistant gram-negative bacteria.

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641100

    authors: Fainstein V,Le Blanc B,Bodey GP

    更新日期:1983-01-01 00:00:00

  • Haemophilus aphrophilus meningitis complicated by hydrocephalus in an immunocompetent adult.

    abstract::A case of meningitis due to an unusual organism, Haemophilus aphrophilus in an adult is described. In spite of rapid clearance of the organism from the cerebrospinal fluid with intravenous cefotaxime, fever persisted over 8 days of therapy and infection was complicated by hydrocephalus. H. aphrophilus meningitis is un...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF02770846

    authors: Adeyemi-Doro FA,Hui AC,Ho FN,Ip M

    更新日期:1998-11-01 00:00:00

  • Chlamydia trachomatis in andrologic patients--direct and indirect detection.

    abstract:BACKGROUND:Chlamydia trachomatis is considered to be the most common sexually transmitted disease in Germany. It is currently unclear whether chlamydial infection causes pathological conditions of the male accessory glands with consequences for male infertility. PATIENTS AND METHODS:Within the framework of several pro...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-001-0088-z

    authors: Bollmann R,Engel S,Petzoldt R,Göbel UB

    更新日期:2001-05-01 00:00:00

  • The effects of ciprofloxacin on human chondrocytes in cell culture.

    abstract::Ciprofloxacin is a highly potent antibacterial agent that is used extensively in bone and joint infections. Because of reports of potential chondro-toxicity in animals, the effects of this drug on cells derived from human cartilage were tested in liquid micromass and agarose gel cultures. An inhibition of cell prolife...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01713325

    authors: Mont MA,Mathur SK,Frondoza CG,Hungerford DS

    更新日期:1996-03-01 00:00:00

  • Thyroiditis due to Brucella melitensis--report of two cases.

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01642110

    authors: von Graevenitz A,Colla F

    更新日期:1990-05-01 00:00:00

  • A survey of ATRIPLA use in clinical practice as first-line therapy in HIV-positive persons in Europe.

    abstract::ATRIPLA is licensed for use only in HIV-positive persons whose viral loads <50 for ≥ 3 months. We investigated the use of ATRIPLA as first-line antiretroviral therapy (ART) in EuroSIDA using a web-based survey performed in Autumn 2012. 96/112 clinics (85.7 %) completed the survey. Recommendations when initiating first...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-014-0630-4

    authors: Mocroft A,Reiss P,Rakhmanova A,Banhegyi D,Phillips AN,De Wit S,Ristola M,Lundgren JD,Grarup J,Kirk O,EuroSIDA in EuroCOORD.

    更新日期:2014-08-01 00:00:00

  • Recommendations for the management of acute hepatitis B: position paper of the Italian Society for the Study of Infectious and Tropical Diseases (SIMIT).

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    journal_title:Infection

    pub_type: 杂志文章,实务指引,评审

    doi:10.1007/s15010-014-0642-0

    authors: Bruno R,Carosi G,Coppola N,Gaeta GB,Puoti M,Santantonio T,Taliani G,Armignacco O,Sagnelli E,Andreoni M,Angarano G,Di Perri G,D'Offizi G,Galli M,Rizzardini G,Italian Society for the Study of Infectious and Tropical Diseases.

    更新日期:2014-10-01 00:00:00

  • Subacute invasive pulmonary aspergillosis as a rare cause of pneumothorax in immunocompetent patient: brief report.

    abstract::Subacute invasive pulmonary aspergillosis (IPA) represents a form of chronic pulmonary aspergillosis which affects immunocompetent individuals or mildly immunocompromised persons with underlying pulmonary disease. Pneumothorax can be a rare complication of subacute IPA due to a leakage of air from an air-filled lung c...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-017-0994-3

    authors: Vukicevic TA,Dudvarski-Ilic A,Zugic V,Stevanovic G,Rubino S,Barac A

    更新日期:2017-06-01 00:00:00