Abstract:
PURPOSE:There is currently a paucity of published literature focused on the treatment of infections caused by NDM-producing organisms. METHODS:We describe a case of a bacteraemia caused by an extensively drug-resistant (XDR) New Delhi metallo-β-lactamase (NDM)-producing Serratia marcescens and review the treatment options for XDR NDM-producing Enterobacteriaceae. RESULTS:Infections caused by New Delhi beta-lactamase (NDM)-producing Enterobacteriaceae are becoming increasingly prevalent worldwide. The presence of the enzyme results in multidrug-resistant and extensively drug-resistant phenotypes which often pose a treatment challenge. Despite this challenge, case reports and series have demonstrated good clinical outcomes with numerous treatment options in comparison to infections due to KPC-producing Enterobacteriaceae. CONCLUSIONS:Further good-quality research focused on the treatment of NDM-producing Enterobacteriaceae is warranted.
journal_name
Infectionjournal_title
Infectionauthors
Chibabhai V,Nana T,Bosman N,Thomas T,Lowman Wdoi
10.1007/s15010-017-1070-8subject
Has Abstractpub_date
2018-02-01 00:00:00pages
1-13issue
1eissn
0300-8126issn
1439-0973pii
10.1007/s15010-017-1070-8journal_volume
46pub_type
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