[Erythromycin determination in organ tissues (author's transl)].

Abstract:

:The recovery rates of erythromycin after in vitro and in vivo administration were studied comparatively in liver, lung, and kidney. Using buffer standards the recovery rate in homogenates of in vitro administered erythromycin decreased with increasing protein concentration. At constant protein concentration the erythromycin administered recovered correlated linearly. Mincing the tissues with scissors was not found to be adequate, even when followed by a diffusion period of up to 24 hours. Similarly, shock freezing resulted in lower values. Even and optimal breaking down of tissues was found after homogenisation or ultrasonics. The recovery rates were not raised by treating the tissue with trypsin. There was no evidence of enzymatical erythromycin degradation in liver homogenates under the assay conditions.

journal_name

Infection

journal_title

Infection

authors

Dette GA,Finke U

doi

10.1007/BF01641124

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

S207-10

eissn

0300-8126

issn

1439-0973

journal_volume

7 Suppl 2

pub_type

杂志文章
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    abstract::Surgical principles in the management of intraabdominal infection have remained constant. Rather, it is the application of these principles in selected cases that has varied. Judgement, therefore, becomes paramount for the surgeon. In selected cases multiple planned relaparotomies may be the most effective means of cl...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01726464

    authors: Aprahamian C,Wittmann DH

    更新日期:1991-11-01 00:00:00

  • Were all carbapenemases created equal? Treatment of NDM-producing extensively drug-resistant Enterobacteriaceae: a case report and literature review.

    abstract:PURPOSE:There is currently a paucity of published literature focused on the treatment of infections caused by NDM-producing organisms. METHODS:We describe a case of a bacteraemia caused by an extensively drug-resistant (XDR) New Delhi metallo-β-lactamase (NDM)-producing Serratia marcescens and review the treatment opt...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-017-1070-8

    authors: Chibabhai V,Nana T,Bosman N,Thomas T,Lowman W

    更新日期:2018-02-01 00:00:00

  • High prevalence of latent tuberculosis infection in patients in end-stage renal disease on hemodialysis: Comparison of QuantiFERON-TB GOLD, ELISPOT, and tuberculin skin test.

    abstract:BACKGROUND:Individuals with end-stage renal disease (ESRD) are 10- to 25-fold more likely than immunocompetent people to develop active tuberculosis (TB) and are candidates for being treated for latent TB infection (LTBI). However, diagnosis using the tuberculin skin test (TST) is doubly difficult due to cutaneous aner...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-008-8082-3

    authors: Lee SS,Chou KJ,Su IJ,Chen YS,Fang HC,Huang TS,Tsai HC,Wann SR,Lin HH,Liu YC

    更新日期:2009-04-01 00:00:00

  • Acinetobacter septicemia: a threat to neonates? Special aspects in a neonatal intensive care unit.

    abstract::Acinetobacter is one of the organisms responsible for nosocomial infections in intensive care, neurosurgery, burn and hemodialysis units. There are only a few reports on Acinetobacter infections in neonatal intensive care units. Over a 31 month period, nine cases of Acinetobacter sepsis occurred in our unit, with four...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01728921

    authors: Regev R,Dolfin T,Zelig I,Givoni S,Wolach B

    更新日期:1993-11-01 00:00:00

  • The incidence of fulminant hepatic failure in acute viral hepatitis in Taiwan: increased risk in patients with pre-existing HBsAg carrier state.

    abstract::The incidence of fulminant hepatitis in Taiwan was studied in a series of consecutive 523 patients with acute viral hepatitis including 11 with acute hepatitis A, 67 with acute hepatitis B, 124 with acute hepatitis NANB and 321 acute hepatitis in HBsAg carriers (patients who were HBsAg positive but anti-HBc IgM negati...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01643385

    authors: Chu CM,Liaw YF

    更新日期:1990-07-01 00:00:00

  • [Fosfomycin concentrations in serum and bile (author's transl)].

    abstract::40 patients were given a single, short intravenous infusion of 4 g fosfomycin over a period of five to ten minutes. In 23 patients, the contents of the gall bladder were removed intra-operatively 30-105 minutes after the fosfomycin infusion. In 17 patients who had undergone cholecystectomy eight to ten days earlier, b...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01640831

    authors: Müller O,Rückert U,Walter W,Haag R,Sauer W

    更新日期:1982-01-01 00:00:00

  • Tuberculous meningitis in adults: review of 61 cases.

    abstract:BACKGROUND:Tuberculosis is still a major cause of serious illness in developing countries. The objective of this study was to assess the clinical, laboratory, radiological and prognostic features of tuberculous meningitis (TBM) in immuncompetent adult patients. PATIENTS AND METHODS:Sixty-one patients with confirmed or...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-003-3179-1

    authors: Sütlaş PN,Unal A,Forta H,Senol S,Kirbaş D

    更新日期:2003-12-01 00:00:00

  • Prevalence of antibodies to human herpesviruses and hepatitis B virus in patients at different stages of human immunodeficiency virus (HIV) infection.

    abstract::The results of antibody assays for viruses of the herpes group (HSV, EBV, VZV and CMV) and for hepatitis B virus (HBV) were retrospectively evaluated in 439 HIV-seropositive patients classified into different stages of HIV infection. The prevalence of specific IgG, IgM and IgA antibodies in these groups was compared w...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01643233

    authors: Enzensberger R,Braun W,July C,Helm EB,Doerr HW

    更新日期:1991-05-01 00:00:00

  • Protective effect of an outer membrane vaccine against Pseudomonas aeruginosa infection.

    abstract::The outer membrane proteins, F, H2 and I, from PA12 strain of Pseudomonas aeruginosa, were purified and used successfully for immunization of Balb/c mice. The immunized mice were protected against challenge with a 2-26 fold LD50 of all known 19 serogroups of P. aeruginosa. ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01647755

    authors: von Specht BU,Strigl G,Ehret W,Brendel W

    更新日期:1987-01-01 00:00:00

  • Assays of cephalosporin antibiotics administered prophylactically in open heart surgery. Determination of serum and tissue levels before, during and after cardiopulmonary bypass.

    abstract::Twenty-eight patients who underwent open-heart surgery were divided into three groups, each of which received a different antibiotic from the cephalosporin series (cephalotin, cefazolin or cefamandole) in order to prevent infection. All antibiotics were given via intravenous infusion in a dosage of 2 g prior to surger...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641087

    authors: Eigel P,Tschirkov A,Satter P,Knothe H

    更新日期:1978-01-01 00:00:00

  • A stringent preemptive protocol reduces cytomegalovirus disease in the first 6 months after kidney transplantation.

    abstract:BACKGROUND:The optimal strategy to prevent cytomegalovirus (CMV) disease after kidney transplantation continues to be open to debate. The preemptive approach requires regular determination of CMV viremia and prompt initiation of therapy. METHODS:We retrospectively compared the incidence of CMV disease during two perio...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-012-0343-5

    authors: Greiner M,Cusini A,Ruesch M,Schiesser M,Ledergerber B,Fehr T,Mueller NJ

    更新日期:2012-12-01 00:00:00

  • Development of sulphonamide-trimethoprim combinations for urinary tract infections. Part 2: Comparative pharmacokinetics of five sulphonamides.

    abstract::The pharmacokinetics and renal excretion of the sulphonamides sulphachloropyridazine, sulphadiazine, sulphaisodimidine, sulphamerazine, and sulphamethoxazole were investigated in a cross-over study with doses of 800 mg each. The serum half-life, urine levels, distribution volume, protein binding and potential antibact...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01639015

    authors: Ortengren B,Fellner H,Bergan T

    更新日期:1979-01-01 00:00:00

  • Efficacy and effects on pulmonary function tests of weekly 600 mg aerosol pentamidine as prophylaxis against Pneumocystis carinii pneumonia.

    abstract::A prospective study was designed to evaluate the efficacy and effects on pulmonary function tests of weekly 600 mg aerosolised pentamidine as prophylaxis against Pneumocystis carinii pneumonia (PCP) amongst two groups of patients infected with the human immunodeficiency virus. Group 1 (primary prophylaxis) consisted o...

    journal_title:Infection

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF01704600

    authors: Ong EL,Dunbar EM,Mandal BK

    更新日期:1992-05-01 00:00:00

  • Cefodizime given once daily for the treatment of upper urinary tract infections and complicated lower urinary tract infections.

    abstract::The efficacy of cefodizime (CDZ) in upper urinary tract infections (UUTI) and complicated lower urinary tract infections (LUTI) was assessed by analysis of the combined results of five clinical trials. Doses of CDZ 1 g i.m. daily, 1 x 2 g i.v. or i.m. and 2 x 2 g i.v. were investigated; comparative agents were cefurox...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01709945

    authors: Hofstetter AG

    更新日期:1992-01-01 00:00:00

  • In-vitro susceptibility of cefoperazone-susceptible and -resistant gram-negative rods to cefoperazone plus sulbactam, other beta-lactams, aminoglycosides and quinolone.

    abstract::We compared the in-vitro activity of cefoperazone-sulbactam (2:1), other beta-lactams, amino-glycosides and ciprofloxacin against cefoperazone-susceptible and -resistant nosocomial gram-negative bacilli. Resistant isolates including Pseudomonas aeruginosa were susceptible to cefoperazone-sulbactam; the susceptible iso...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01643761

    authors: Chandrasekar PH,Sluchak JA

    更新日期:1991-01-01 00:00:00

  • In vitro activity, pharmacokinetics, clinical safety and therapeutic efficacy of enoxacin in the treatment of patients with complicated urinary tract infections.

    abstract::Minimal inhibitory concentrations (MIC) of enoxacin, nalidixic acid, pipemidic acid, norfloxacin, ciprofloxacin, ofloxacin and pefloxacin against isolates from 400 urological in-patients with complicated urinary tract infections (UTI) were determined by means of an agar dilution technique (10(4) cfu, multipointer). 28...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01667215

    authors: Naber KG,Sörgel F,Gutzler F,Bartosik-Wich B

    更新日期:1985-09-01 00:00:00

  • Combination therapy with an aminoglycoside for Staphylococcus aureus endocarditis and/or persistent bacteremia is associated with a decreased rate of recurrent bacteremia: a cohort study.

    abstract:PURPOSE:Although limited data exist on the efficacy and potential risk of synergistic aminoglycoside therapy for persistent Staphylococcus aureus bacteremia and endocarditis, aminoglycosides are frequently used in clinical practice. METHODS:As our study population, we included subjects fulfilling the modified Duke cri...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0189-2

    authors: Lemonovich TL,Haynes K,Lautenbach E,Amorosa VK

    更新日期:2011-12-01 00:00:00

  • Correction to: Mucormycosis in hospitalized patients at a tertiary care center in Lebanon: a case series.

    abstract::The spelling of the name "Ali Bazarbachi" was incorrect. ...

    journal_title:Infection

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s15010-018-1203-8

    authors: El Zein S,El-Sheikh J,Zakhem A,Ibrahim D,Bazarbachi A,Kanj SS

    更新日期:2018-12-01 00:00:00

  • Chlamydia trachomatis in andrologic patients--direct and indirect detection.

    abstract:BACKGROUND:Chlamydia trachomatis is considered to be the most common sexually transmitted disease in Germany. It is currently unclear whether chlamydial infection causes pathological conditions of the male accessory glands with consequences for male infertility. PATIENTS AND METHODS:Within the framework of several pro...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-001-0088-z

    authors: Bollmann R,Engel S,Petzoldt R,Göbel UB

    更新日期:2001-05-01 00:00:00

  • Low rate of clinical consequences derived from results of blood cultures obtained in an internal medicine emergency department.

    abstract:BACKGROUND:Blood cultures detect bacteremia in individual patients and help define local pathogen and resistance spectra. At the same time, the benefits of blood culture results in the management of individual patients -- and therefore their cost-effectiveness -- are disputed. PATIENTS AND METHODS:During 1 calendar ye...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-005-5065-5

    authors: Ehrenstein BP,Jarry T,Linde HJ,Schölmerich J,Glück T

    更新日期:2005-10-01 00:00:00

  • The binding of Chlamydia trachomatis and zinc to McCoy cells (mouse fibroblasts).

    abstract::Zinc was found to have profoundly different effects upon the infection of McCoy cells (mouse fibroblasts) by two strains of Chlamydia trachomatis dependent upon the time and concentration of zinc exposure. Radiolabeled zinc-65 became McCoy cell-associated in a manner independent of incubation temperature, but highly d...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01646116

    authors: Sugarman B,Agbor P

    更新日期:1987-01-01 00:00:00

  • Oxacillin-susceptible methicillin-resistant Staphylococcus aureus (OS-MRSA), a hidden resistant mechanism among clinically significant isolates in the Wessex region/UK.

    abstract:PURPOSE:Methicillin-resistant Staphylococcus aureus (MRSA) is defined as S. aureus genetically having the mecA or mecC genes or phenotypically showing minimum inhibitory concentration (MIC) of oxacillin higher than 2 mg/L. However, recently, cefoxitin/oxacillin-susceptible mecA-positive S. aureus (OS-MRSA) has been rep...

    journal_title:Infection

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s15010-014-0641-1

    authors: Saeed K,Ahmad N,Dryden M,Cortes N,Marsh P,Sitjar A,Wyllie S,Bourne S,Hemming J,Jeppesen C,Green S

    更新日期:2014-10-01 00:00:00

  • Anti-V3 loop spectrotype in HIV-infected individuals during zidovudine therapy.

    abstract::In order to investigate the role played by zidovudine (ZDV) as immune modulator, particularly on B-cell response, the anti-V3 loop spectrotype in 115 sera from 26 HIV-infected individuals was evaluated, prior to and during treatment with ZDV, by isoelectric focusing and reverse blotting (IEF-RB), a technique useful fo...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01781097

    authors: Biselli R,Del Bono V,Anselmo M,Canessa A,Mazzarello G,D'Amelio R,Bassetti D

    更新日期:1996-05-01 00:00:00

  • Do antibody-coated bacteria prove bacterial prostatitis?

    abstract::Using the immunofluorescence technique in 187 patients with bacteriologically proven prostatitis according to the Meares-Stamey test demonstrated a significant amount of antibody-coated bacteria (ACB) in their ejaculates. The ACB test was useful to discriminate between chronic bacterial prostatitis and prostatodynia w...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01643684

    authors: Riedasch G,Möhring K,Ritz E

    更新日期:1991-01-01 00:00:00

  • Ceftizoxime (FK 749) in vitro antibacterial activity.

    abstract::The minimal inhibitory concentrations of ceftizoxime, cefotaxime, moxalactam, cefoperazone, cefotiam and cefamandole were determined against various species of gram-negative bacteria and against Staphylococcus aureus. Ceftizoxime was more active against Enterobacteriaceae than cefamandole, cefotiam and cefoperazone an...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641024

    authors: Husson MO,Courcol R,Izard D,Leclerc H

    更新日期:1984-01-01 00:00:00

  • Surgical Site Infections after glioblastoma surgery: results of a multicentric retrospective study.

    abstract:BACKGROUND:The effects of surgical site infections (SSI) after glioblastoma surgery on patient outcomes are understudied. The aim of this retrospective multicenter study was to evaluate the impact of SSI on the survival of glioblastoma patients. METHODS:Data from SSI cases after glioblastoma surgeries between 2009 and...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-020-01534-0

    authors: Salle H,Deluche E,Couvé-Deacon E,Beaujeux AC,Pallud J,Roux A,Dagain A,de Barros A,Voirin J,Seizeur R,Belmabrouk H,Lemnos L,Emery E,Fotso MJ,Engelhardt J,Jecko V,Zemmoura I,Le Van T,Berhouma M,Cebula H,Peyre M,Pr

    更新日期:2020-10-09 00:00:00

  • Socioeconomic impact on device-associated infections in limited-resource neonatal intensive care units: findings of the INICC.

    abstract:PURPOSE:To evaluate the impact of country socioeconomic status and hospital type on device-associated healthcare-associated infections (DA-HAIs) in neonatal intensive care units (NICUs). METHODS:Data were collected on DA-HAIs from September 2003 to February 2010 on 13,251 patients in 30 NICUs in 15 countries. DA-HAIs ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0136-2

    authors: Rosenthal VD,Lynch P,Jarvis WR,Khader IA,Richtmann R,Jaballah NB,Aygun C,Villamil-Gómez W,Dueñas L,Atencio-Espinoza T,Navoa-Ng JA,Pawar M,Sobreyra-Oropeza M,Barkat A,Mejía N,Yuet-Meng C,Apisarnthanarak A,International N

    更新日期:2011-10-01 00:00:00

  • Correction to: The diagnosis and treatment of urogenital schistosomiasis in Italy in a retrospective cohort of immigrants from Sub-Saharan Africa.

    abstract::The original version of this article unfortunately contained a mistake. The given name and family name of Filippo Parretti was transposed in the original publication. The correct name is as shown above. ...

    journal_title:Infection

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s15010-019-01283-9

    authors: Tilli M,Gobbi F,Rinaldi F,Testa J,Caligaris S,Magro P,Buonfrate D,Degani M,Minervini A,Carini M,Tuccio A,Sforza S,Gulletta M,Castelli F,Agostini S,Parretti F,Richter J,Olliaro P,Bisoffi Z,Bartoloni A,Zammarchi L

    更新日期:2019-06-01 00:00:00

  • Thyroiditis due to Brucella melitensis--report of two cases.

    abstract::Two cases of thyroiditis due to Brucella melitensis are reported. Both occurred in foreigners working in Switzerland and presented with characteristic symptoms of thyroiditis which masked those of brucellosis. Cultures were diagnostic. One patient had concomitant thyroid malignancy. Both showed normal thyroid function...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01642110

    authors: von Graevenitz A,Colla F

    更新日期:1990-05-01 00:00:00

  • Changes in lymphocyte subpopulations in patients treated with cefodizime for acute lower respiratory tract infections.

    abstract::The influence of cefodizime (CDZ) on CD4 and CD8 lymphocytes was investigated in patients with lower respiratory tract infection and underlying respiratory diseases. Ten men and one woman were treated with CDZ 1 g i.m. b.i.d. for ten days. The infecting organisms were Haemophilus influenzae (5), Streptococcus pneumoni...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01709955

    authors: Valcke Y,Van der Straeten M

    更新日期:1992-01-01 00:00:00