Abstract:
:The pharmacokinetics and renal excretion of the sulphonamides sulphachloropyridazine, sulphadiazine, sulphaisodimidine, sulphamerazine, and sulphamethoxazole were investigated in a cross-over study with doses of 800 mg each. The serum half-life, urine levels, distribution volume, protein binding and potential antibacterial activity in the urine renders sulphadiazine the preferred component in a combination tablet together with trimethoprim for the treatment of urinary tract infections.
journal_name
Infectionjournal_title
Infectionauthors
Ortengren B,Fellner H,Bergan Tdoi
10.1007/BF01639015subject
Has Abstractpub_date
1979-01-01 00:00:00pages
S367-70eissn
0300-8126issn
1439-0973journal_volume
7 Suppl 4pub_type
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