Basis and results of therapy with Beta-lactam antibiotics in experimental infections.

abstract：PURPOSE:This study aimed to describe the epidemiology of childhood group B streptococcus (GBS) disease including late late-onset disease (LLOD) and to clinically characterize recurrent cases and twin-sibling cases in Japan. METHODS:We collected information on infants (<1 year of age) with invasive GBS disease and inst...

journal_title：Infection

authors： Matsubara K,Hoshina K,Kondo M,Miyairi I,Yukitake Y,Ito Y,Minami K,Genkawa R

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:It is routine practice to provide chemoprophylaxis for close contacts of a patient infected with meningococci. PATIENTS:When a 17-year-old boy living in a boys' home was admitted to the hospital with septic shock caused by Neisseria meningitidis, we immediately identified contact persons in the boys' home. ...

journal_title：Infection

authors： Linde H,Glück T,Metz M,Reng C,Erlmeier S,Lehn N

更新日期：2000-05-01 00:00:00

abstract：:The results obtained during the investigation on the excretion of nine urinary antigens originating in the kidney and characterized by monoclonal antibodies and of the brush-border marker-enzyme alanine aminopeptidase in the urine of 12 volunteers before and during the administration of therapeutic doses of ciprofloxa...

journal_title：Infection

authors： Falkenberg FW,Mondorf AW

更新日期：1988-01-01 00:00:00

abstract：:Satisfactory methods for the serodiagnosis of Chlamydia trachomatis have been widely discussed in recent years. Until a decade ago, the complement-fixation test measuring group-specific antibody was the most widely applied technique. However, despite showing relatively high diagnostic sensitivity in systemic chlamydia...

journal_title：Infection

authors： Treharne JD

更新日期：1982-01-01 00:00:00

abstract：:A fatal guinea pig model of pneumococcal pneumonia was developed in order to evaluate the efficacy of amoxicillin combined with either pentoxifylline or dexamethasone. Parameters assessed were survival time and lung changes (alterations, bacterial colony counts, inducible nitric oxide synthase [iNOS] and cyclooxygenas...

journal_title：Infection

authors： Parra A,García-Olmos M,Nieto E,García-Calvo G,Ponte C,Soriano F

更新日期：2002-06-01 00:00:00

abstract：:In most cases of respiratory tract infection, antibiotic therapy has to be initiated before the results of microbiological examination are available. The four most common pathogens of acute exacerbations of chronic bronchitis are pneumococci, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus. Pne...

journal_title：Infection

authors： Vogel F

更新日期：1993-01-01 00:00:00

abstract：:Polymorphonuclear leukocyte (PMNL) chemotaxis was evaluated in ten healthy volunteers who had received 600 mg of clindamycin intramuscularly. Serum obtained 3 hours after the administration of clindamycin significantly increased PMNL chemotaxis. Serum obtained at 12 and 24 hours after the administration of the drug di...

journal_title：Infection

authors： Skoutelis AT,Lianou PE,Bassaris HP

更新日期：1993-09-01 00:00:00

abstract：:A prospective study was designed to evaluate the efficacy and effects on pulmonary function tests of weekly 600 mg aerosolised pentamidine as prophylaxis against Pneumocystis carinii pneumonia (PCP) amongst two groups of patients infected with the human immunodeficiency virus. Group 1 (primary prophylaxis) consisted o...

journal_title：Infection

authors： Ong EL,Dunbar EM,Mandal BK

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Infections caused by bacteria are a foremost cause of morbidity and mortality in the world. The common strategy of treating bacterial infections is by local or systemic administration of antimicrobial agents. Currently, the increasing antibiotic resistance is a serious and global problem. Since the most impo...

journal_title：Infection

authors： Asadi A,Razavi S,Talebi M,Gholami M

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Aspiration pneumonia (AP) and primary lung abscess (PLA), are diseases following aspiration of infectious material from the oropharynx or stomach. An antibiotic therapy, also covering anaerobic pathogens, is the treatment of choice. In this study we compared moxifloxacin (MXF) and ampicillin/sulbactam (AMP/S...

journal_title：Infection

authors： Ott SR,Allewelt M,Lorenz J,Reimnitz P,Lode H,German Lung Abscess Study Group.

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:In a study involving 200 patients, we previously found that 17.5% of patients developed viridans streptococcal (VS) bacteremia following autologous peripheral blood stem cell transplantation (aPBSCT) when ciprofloxacin or ciprofloxacin plus ampicillin was used for prophylaxis. PATIENTS AND METHODS:A retrosp...

journal_title：Infection

authors： Naqvi B,Dorsky D,Ali SA,Feingold JM,Edwards RL,Bona RD,Clive J,Tutschka PJ,Bilgrami S

更新日期：2001-08-01 00:00:00

abstract：:The MICs and MBCs of mecillinam, ticarcillin, mezlocillin, azlocillin and piperacillin were determined by the microdilution method in liquid medium using 700 strains of gram-negative bacilli and enterococci isolated from pathological sources and classified as a function of their sensitivity to ampicillin and carbenici...

journal_title：Infection

authors： Thabaut A,Durosoir JL,Saliou P

更新日期：1982-01-01 00:00:00

abstract：:Intestinal infection by Escherichia coli O157 and other verotoxin (VT) producing E. coli has been increasingly recognized as an important factor for the causation of classic (enteropathic) hemolytic uremic syndrome (HUS) and hemorrhagic colitis (HC). Toxins most frequently involved are VT1 and VT2. As with other toxin...

journal_title：Infection

authors： Bitzan M,Klemt M,Steffens R,Müller-Wiefel DE

更新日期：1993-05-01 00:00:00

abstract：:Efficacy of Oral Ofloxacin and Ciprofloxacin. Cross-over Study. The efficacy of the 4-quinolones ciprofloxacin (CPX) and ofloxacin (OFX) was studied in a cross-over study. Twenty out-patients with cystic fibrosis and chronic colonization of the respiratory tract with Pseudomonas aeruginosa were treated for ten days wi...

journal_title：Infection

authors： Kurz CC,Marget W,Harms K,Bertele RM

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:Limited data are available on immunologic responses to primary pandemic H1N1 (2009) vaccination in recipients of allogeneic hematopoietic stem cell transplantation (HSCT) recipients. In 2009 serologic responses to either pandemic H1N1 (2009) vaccine (n = 36) or pandemic H1N1 (2009) infection (n = 2) were studie...

journal_title：Infection

authors： Roll D,Ammer J,Holler B,Salzberger B,Schweiger B,Jilg W,Andreesen R,Edinger M,Wolff D,Holler E

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:In endemic countries with a high level of chloroquine resistance, Plasmodium vivax malaria is associated with high morbidity and mortality. In these areas, the dihydroartemisinin-piperaquine combination resulted in clinical response, a more rapid clearance of parasitaemia, compared to chloroquine therapies, ...

journal_title：Infection

authors： Corpolongo A,Pisapia R,Oliva A,Giancola ML,Mencarini P,Bevilacqua N,Ghirga P,Mariano A,Vulcano A,Paglia MG,Nicastri E

更新日期：2019-08-01 00:00:00

abstract：:As perioperative prophylaxis for major orthopedic operations 81 patients were given the fixed combination of ampicillin (1 g)/sulbactam (0.5 g) or cefotiam (2 g) as short infusions. The three beta-lactams were rapidly distributed into the different tissues and their pharmacokinetic profiles were found to be very simil...

journal_title：Infection

authors： Wildfeuer A,Mallwitz J,Gotthardt H,Hille E,Gruber H,Dahmen G,Pfaff G,Göbel C

更新日期：1997-07-01 00:00:00

abstract：:There is a correlation between tissue oxygen tension, incidence of infection and disturbance of wound healing. Scientific investigations in recent years have documented that infection and tissue repair are processes consuming oxygen. Animal experiments have shown that oxygenation of the tissue is essential for the eli...

journal_title：Infection

authors： Kühne HH,Ullmann U,Kühne FW

更新日期：1985-03-01 00:00:00

abstract：:To investigate the diagnostic value of a direct immunofluorescence test (DIF-test), urethral samples and first catch urine (FCU) from 153 male patients attending an outpatient clinic for sexually transmitted diseases (STD) were studied. Of the male patients, 40 (26.1%) had a positive urethral culture, 39 (25.5%) had a...

journal_title：Infection

authors： Stary A,Genç M,Heller-Vitouch C,Mårdh PA

更新日期：1992-03-01 00:00:00

abstract：:To assess the in vitro activity of cefpodoxime against anaerobic respiratory tract and oropharyngeal pathogens 77 strains belonging to 18 gram-negative and 7 gram-positive species were studied by means of agar dilution tests. For comparison cefuroxime, amoxicillin, amoxicillin + clavulanic acid and clindamycin were al...

journal_title：Infection

authors： Werner H,Heizmann WR,Höflsauer M

更新日期：1991-09-01 00:00:00

abstract：:A total of 208 patients underwent brain biopsy for presumptive herpes simplex encephalitis and were randomized to receive either vidarabine, vira-A, at 15 mg/kg/day, or acyclovir, at 30 mg/kg/day for ten days. 69 patients (33%) had biopsy-proven disease; 37 received vira-A and 32 acyclovir. With the exception of age, ...

journal_title：Infection

authors： Whitley RJ,Alford CA,Hirsch MS,Schooley RT,Luby JP,Aoki FY,Hanley D,Nahmias AJ,Soong SJ

更新日期：1987-01-01 00:00:00

abstract：:A follow-up study of mother to infant transmission of hepatitis B virus was conducted in the Philippines between 1981 and 1983. The prevalence of HBsAg among 527 mothers was 8.5%. Overall, seven out of 17 (41.2%) infants born to HBsAg carrier mothers became HBsAg positive within the first 12 months of life. The risk o...

journal_title：Infection

authors： Lingao AL,Torres NT,Muñoz N,Lansang MA,West SK,Bosch FX,Domingo EO

更新日期：1989-09-01 00:00:00

abstract：PURPOSE:Cryptococcal meningitis is a potentially fatal fungal infection associated with a significant attributable morbidity and mortality, especially among HIV/AIDS patients. The first-line therapy for the treatment of this clinical entity is the combinatory therapy of amphotericin B plus flucytosine. However, the hig...

journal_title：Infection

authors： Villanueva-Lozano H,Treviño-Rangel RJ,González GM,Hernández-Rodríguez PA,Camacho-Ortiz A,Castillo-Reyna L,Galindo-Alvarado SG,Martínez-Reséndez MF

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the efficacy of sustained release of vancomycin and teicoplanin from a resorbable gelatin glycerol sponge, in order to establish a new delivery system for local anti-infective therapy. MATERIALS AND METHODS:60 plasticized glycerol gelatin sponges containing either 10 or...

journal_title：Infection

authors： Drognitz O,Thorn D,Krüger T,Gatermann SG,Iven H,Bruch HP,Muhl E

更新日期：2006-02-01 00:00:00

abstract：PURPOSE:Chlamydophila pneumoniae has been implicated in atherosclerosis/restenosis; however, clear evidence is missing. Therefore, the aim of our study was to examine the influence of intimal infection and systemic inflammation on cardiovascular complications after coronary intervention. METHODS:45 atheroma specimens ...

journal_title：Infection

authors： Tuleta I,Reek D,Braun P,Bauriedel G,Nickenig G,Skowasch D,Andrié R

更新日期：2015-02-01 00:00:00

abstract：:Mediterranean spotted fever, caused by Rickettsia conorii, is a tick-borne infection. Serum samples for screening R. conorii antibodies of professionally exposed persons in the Antalya region, on the Mediterranean coast of Turkey, were analyzed. R. conorii IgG antibodies were detected in 13 of 98 (13.3%) serum samples...

journal_title：Infection

authors： Vural T,Ergin C,Sayin F

更新日期：1998-05-01 00:00:00

abstract：:The concentrations of ciprofloxacin produced in bone, cartilage and menisci after a single administration of 200 mg were determined at different intervals in a group of patients with an average age of 80 years. Concentrations of 0.11 to 0.94 mg/kg bone tissue were measured after 0.5 to 5 hours. In the cartilage a conc...

journal_title：Infection

authors： Wacha H,Wagner D,Schäfer V,Knothe H

更新日期：1990-05-01 00:00:00

abstract：:Penetration of ciprofloxacin into human tonsils was studied following an intravenous infusion of 200 mg over 15 minutes to adult humans undergoing tonsillectomy. Samples were taken one-and-a-half to four hours after dosing. Generally, tissue levels exceeded corresponding serum concentrations by 50% (range of intraindi...

journal_title：Infection

authors： Falser N,Dalhoff A,Weuta H

更新日期：1984-09-01 00:00:00

abstract：:Aztreonam was given intravenously at a dose of 1 g at induction of anaesthesia, followed by subsequent doses of 1 g at eight hour intervals during 48 hours to 20 patients undergoing colorectal surgery. A series of serum and faecal specimens were taken for analysis of aztreonam concentrations. Tissue samples from the g...

journal_title：Infection

authors： Kager L,Brismar B,Malmborg AS,Nord CE

更新日期：1985-05-01 00:00:00

abstract：:Primary hepatocellular carcinoma (PHC) has been linked etiologically to chronic hepatitis B virus (HBV) infection by epidemiologic and molecular lines of evidence. Serologic evidence of HBV and hepatitis delta virus (HDV) infection was assessed in sera from 47 Greek patients with PHC. Radioimmunoassays for the detecti...

journal_title：Infection

authors： Tassopoulos NC,Theodoropoulos G,Sjogren MH,Engle R,Purcell RH

更新日期：1989-01-01 00:00:00