Pharmacokinetics of ampicillin, sulbactam and cefotiam in patients undergoing orthopedic surgery.

abstract：:Indwelling urinary catheters play a very important part in urology. However, their use is accompanied by a considerable increase in the risk of nosocomial urinary tract infections. The pathophysiological cause is ascribed to pathogens that adhere to the catheter surface, proliferate and produce a biofilm. In addition ...

journal_title：Infection

authors： Rösch W,Lugauer S

更新日期：1999-01-01 00:00:00

abstract：:To quantify the relative antibacterial efficacy of beta-lactam antibiotics in vitro, a mathematical description of bacterial growth was developed. Curves of growth in the presence of the antibiotic are expressed as quadratic functions of time, with initial growth rate (ko) and rate of change of growth (a) as concentra...

journal_title：Infection

authors： Mattie H,van der Voet GB

更新日期：1979-01-01 00:00:00

abstract：:Surgical principles in the management of intraabdominal infection have remained constant. Rather, it is the application of these principles in selected cases that has varied. Judgement, therefore, becomes paramount for the surgeon. In selected cases multiple planned relaparotomies may be the most effective means of cl...

journal_title：Infection

authors： Aprahamian C,Wittmann DH

更新日期：1991-11-01 00:00:00

abstract：:The efficacy of different therapeutic regimens for Lyme arthritis is reviewed. The first treatment for Lyme arthritis, intramuscular benzathine penicillin 2.4 million units weekly for 3 weeks, had a success rate of 35%. Another study employed intravenous penicillin G at a dosage of 20 million units daily for 10 days, ...

journal_title：Infection

authors： Cimmino MA,Moggiana GL,Parisi M,Accardo S

更新日期：1996-01-01 00:00:00

abstract：:The great majority of individuals with human immunodeficiency virus type 1 (HIV-1) infection presents with no signs or symptoms, or only lymphadenopathy. To initiate prophylactic measures in time it is necessary to establish risk criteria. CD4+ cell counts are significant predictors. Supplementary methods to improve t...

journal_title：Infection

authors： Fuchs D,Krämer A,Reibnegger G,Werner ER,Dierich MP,Goedert JJ,Wachter H

更新日期：1991-01-01 00:00:00

abstract：:The ability of clavulanic acid to inactivate beta-lactamase was investigated using 47 amoxicillin-resistant bacteria. In the presence of 10 mg/l clavulanic acid most strains of staphylococci, Escherichia coli, Klebsiella and Proteus mirabilis became fully amoxicillin-sensitive. This effect of clavulanic acid was in mo...

journal_title：Infection

authors： Peters G,Pulverer G,Neugebauer M

更新日期：1980-01-01 00:00:00

abstract：:The original version of this article unfortunately contained a mistake. ...

journal_title：Infection

authors： Sagnelli C,Macera M,Pisaturo M,Zampino R,Coppola N,Sagnelli E

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:Optimal antimicrobial treatment duration for Gram-negative bloodstream infection (BSI) remains unclear. This retrospective cohort study examined effectiveness of short (7-10 days) and long (>10 days) courses of antimicrobial therapy for uncomplicated Gram-negative BSI. METHODS:Hospitalized adults with uncompli...

journal_title：Infection

authors： Nelson AN,Justo JA,Bookstaver PB,Kohn J,Albrecht H,Al-Hasan MN

更新日期：2017-10-01 00:00:00

abstract：:The main objective was to develop a scoring system for easy use by the physician in daily clinical practice in deciding the appropriate treatment for his herpes zoster patient. Data from 635 patients who did not receive antiviral therapy were included in this analysis. Of these, 131 developed postherpetic neuralgia (P...

journal_title：Infection

authors： Meister W,Neiss A,Gross G,Doerr HW,Höbel W,Malin JP,von Essen J,Reimann BY,Witke C,Wutzler P

更新日期：1998-11-01 00:00:00

abstract：:The assay described is an agar diffusion test using Bacillus stearothermophilus as test organism. Incubation is at 62 degrees C; results can be obtained rapidly within 2 to 3 hours. The test was developed for the determination of gentamicin concentrations in serum and other body fluids. Because of its high sensitivity...

journal_title：Infection

authors： Wahlig H

更新日期：1977-01-01 00:00:00

abstract：:Fusobacterium nucleatum is an anaerobic Gram-negative bacillus commensal to the human oropharynx and gastrointestinal tract which causes an array of human infection, yet it has never been associated with infection of prosthetic joints. We report the first case of prosthetic hip infection caused by F. nucleatum in a ma...

journal_title：Infection

authors： Verma K,McNabb PC,Kurtz W,Green J,Trabue CH

更新日期：2012-06-01 00:00:00

abstract：:Influenza viruses type A and B can cause a wide spectrum of illness, and they are responsible for considerable mortality and morbidity. With the new neuraminidase inhibitors, of which zanamivir was the first drug to be licensed, the physician has antivirals at his disposal which are safe and effective against both inf...

journal_title：Infection

authors： Wutzler P,Vogel G

更新日期：2000-09-01 00:00:00

abstract：:In a randomized study, 42 patients undergoing extensive maxillo-facial surgery (correction of the position of the mandible or maxilla by using autologous bone transplants) received prophylactically ten-day courses of either flucloxacillin or amoxicillin with clavulanic acid. Patients were comparable with regard to age...

journal_title：Infection

authors： Vlaspolder F,de Zeeuw G,Rozenberg-Arska M,Egyedi P,Verhoef J

更新日期：1987-07-01 00:00:00

abstract：:A time-dependent degree of immunosuppression or immunostimulation which may be correlated to pharmacokinetic variables was obtained by administering a single dose of ofloxacin, norfloxacin, pipemidic and piromidic acid to healthy volunteers. The plasma samples collected before drug administration and then at various t...

journal_title：Infection

authors： De Simone C,Vullo V,Grassi M,Di Fabio S,Baldinelli L,Sorice F

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:Data on non-fermentative Gram-negative rods (NFGNR) bacteremia in children with malignancies are limited. The aim of this study was to present clinical picture, antimicrobial susceptibility pattern, risk factors for resistance and outcome in NFGNR bacteremia in children with cancer. METHODS:All episodes of NFG...

journal_title：Infection

authors： Averbuch D,Avaky C,Harit M,Stepensky P,Fried I,Ben-Ami T,Temper V,Peled Y,Troen H,Masarwa R,Abu Ahmad W,Weintraub M,Revel-Vilk S,Engelhard D

更新日期：2017-06-01 00:00:00

abstract：:Non-infected standardized burns and those contaminated experimentally with a constant number of organisms of a selected Pseudomonas aeruginosa strain underwent varying forms of treatment with silver sulfadiazine, cefsulodin cream and povidone iodine ointment. Wound healing was controlled by evaluating the wound area. ...

journal_title：Infection

authors： Kaiser W,von der Lieth H,Potel J,Heymann H

更新日期：1984-01-01 00:00:00

abstract：PURPOSE:This retrospective study was performed in order to investigate the clinical characteristics and antibiotic susceptibility of viridans streptococcal bacteremia (VSB) in febrile neutropenic children in the context of the increase in incidence and antibiotic resistance of VSB. METHODS:We conducted this study amon...

journal_title：Infection

authors： Han SB,Bae EY,Lee JW,Lee DG,Chung NG,Jeong DC,Cho B,Kang JH,Kim HK

更新日期：2013-10-01 00:00:00

abstract：:Material from 50 patients with purulent otitis media was investigated. All patients had undergone surgical operation. The results indicate that anaerobic non spore-forming bacteria, especially gram-negative rods of the family Bacteroidaceae, may play an important role in the aetiology of purulent otitis media. In a fu...

journal_title：Infection

authors： Hudác A

更新日期：1980-01-01 00:00:00

abstract：:In an open randomised crossover study the antibacterial activity of pefloxacin and norfloxacin was assessed in the urine after a single 800-mg oral dose in 14 healthy female volunteers. Pefloxacin demonstrated lower peak concentrations in the urine than norfloxacin (mean, 217.2 mg/l versus 492.9 mg/l as determined by ...

journal_title：Infection

authors： Hofbauer H,Naber KG,Kinzig-Schippers M,Sörgel F,Rustige-Wiedemann C,Wiedemann B,Reiz A,Kresken M

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Aspiration pneumonia (AP) and primary lung abscess (PLA), are diseases following aspiration of infectious material from the oropharynx or stomach. An antibiotic therapy, also covering anaerobic pathogens, is the treatment of choice. In this study we compared moxifloxacin (MXF) and ampicillin/sulbactam (AMP/S...

journal_title：Infection

authors： Ott SR,Allewelt M,Lorenz J,Reimnitz P,Lode H,German Lung Abscess Study Group.

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:The Choosing Wisely® initiative is an international campaign addressing over- and underuse of diagnostic and therapeutic measures in infectious diseases among others. Since 2016, the German Society for Infectious Diseases (DGI) has constantly designed new items in this regard. Here we report the most recent rec...

journal_title：Infection

authors： Draenert R,Jung N,Choosing Wisely (Klug entscheiden) DGI Working Group.

更新日期：2020-06-01 00:00:00

abstract：:The minimum inhibitory concentrations (MIC) of ciprofloxacin were determined for 441 uropathogens from patients with complicated and/or hospital acquired urinary tract infections (UTI). None of the Enterobacteriaceae was resistant (MIC > or = 4 mg/l), but 21.7% of enterococci, 28.3% of Pseudomonas spp. and 38.5% of st...

journal_title：Infection

authors： Naber KG,Witte W,Bauernfeind A,Wiedemann B,Wagenlehner F,Klare I,Heisig P

更新日期：1994-01-01 00:00:00

abstract：:Polymerase chain reaction (PCR) analysis with primers for the pp65, a-sequence, glycoprotein B, and major immediate early genes of human cytomegalovirus (CMV) was used to study five congenitally-infected infants and their CMV-infected family members. Family members excreting CMV included three mothers and two siblings...

journal_title：Infection

authors： Souza IE,Gregg A,Pfab D,Dawson JD,Benson P,O'Neill ME,Murph JR,Petheram SJ,Bale JF Jr

更新日期：1997-05-01 00:00:00

abstract：:Recently, important advances have been made in the immunodiagnosis of tuberculosis. New T cell interferon-gamma release assays (TIGRA) are more specific and more sensitive than the tuberculin skin test (TST) for the diagnosis of Mycobacterium tuberculosis (MTB) infection. However, like the TST, TIGRA are unable to dis...

journal_title：Infection

authors： Jafari C,Lange C

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:The rise in the standard of living of the Israeli population during recent decades has been accompanied by a significant decline in the prevalence of various viral diseases including hepatitis A (HAV). This trend is not reflected in the seroprevalence of herpes simplex (HSV) infection, which has remained sta...

journal_title：Infection

authors： Katz J,Gdalevich M,Ashkenazi I,Chaushu G,Shemer J

更新日期：2000-07-01 00:00:00

abstract：PURPOSE:Peripheral facial nerve palsy (FP) is the most common single nerve affection. Most cases are idiopathic, but a relevant fraction is caused by potentially treatable aetiologies including infections. Not all current diagnosis and treatment guidelines recommend routine cerebrospinal fluid (CSF) analysis in the dia...

journal_title：Infection

authors： Henkel K,Lange P,Eiffert H,Nau R,Spreer A

更新日期：2017-04-01 00:00:00

abstract：:Dysbiosis does not necessarily mean disease. Typical clinical picture of disease caused by metabolic activity of dysbiotic microflora is the microbial over-growth syndrome. We studied case histories of 434 patients without consideration of their basic illnesses and correlated them with types of dysbioses of duodenal j...

journal_title：Infection

authors： Knoke M,Bernhardt H

更新日期：1989-07-01 00:00:00

abstract：PURPOSE:In January 2015, we noticed by rectal swab analyses that seven of 23 patients at an early rehabilitation ward had been colonized with carbapenem-resistant Klebsiella pneumoniae (CKP). Here, we describe risk factors for CKP acquisition. METHODS:In the present study, the outbreak is described and risk factors fo...

journal_title：Infection

authors： Borgmann S,Pfeifer Y,Becker L,Rieß B,Siegmund R,Sagel U

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Tuberculosis is still a major cause of serious illness in developing countries. The objective of this study was to assess the clinical, laboratory, radiological and prognostic features of tuberculous meningitis (TBM) in immuncompetent adult patients. PATIENTS AND METHODS:Sixty-one patients with confirmed or...

journal_title：Infection

authors： Sütlaş PN,Unal A,Forta H,Senol S,Kirbaş D

更新日期：2003-12-01 00:00:00

abstract：PURPOSE:Differential diagnosis between acute viral and bacterial infection is an emerging common challenge for a physician in the emergency department. Serum C-reactive protein (CRP) is used to support diagnosis of bacterial infection, but in patients admitted with low CRP, its ability to discriminate between viral and...

journal_title：Infection

authors： Coster D,Wasserman A,Fisher E,Rogowski O,Zeltser D,Shapira I,Bernstein D,Meilik A,Raykhshtat E,Halpern P,Berliner S,Shenhar-Tsarfaty S,Shamir R

更新日期：2020-04-01 00:00:00