Abstract:
BACKGROUND:Viral hepatitis is characterized by special clinical, biochemical and serological findings. This study was planned to determine the seroprevalence, epidemiological characteristics and clinical and biochemical findings of hepatitis A virus (HAV) and hepatitis E virus (HEV) infections during an outbreak of jaundice. MATERIALS AND METHODS:340 children aged 5-16 years were included. Clinical findings and alanine aminotransferase (ALT) levels were documented. Anti-HAV IgG and IgM in addition to anti-HEV IgG and IgM were determined by microELISA. RESULTS:Clinical findings, high levels of ALT, anti-HAV IgM and IgG, anti-HEV IgM and IgG were present in 6%, 23%, 17%, 100%, 7% and 9% of cases, respectively. The relationship between ALT levels and anti-HAV or anti-HEV IgM seropositivity was significant (p = 0.0001). CONCLUSION:HAV and HEV infection were both caused by a contaminated water supply.
journal_name
Infectionjournal_title
Infectionauthors
Yayli G,Kiliç S,Ormeci ARdoi
10.1007/s15010-002-2123-0keywords:
subject
Has Abstractpub_date
2002-12-01 00:00:00pages
334-7issue
6eissn
0300-8126issn
1439-0973journal_volume
30pub_type
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