Pharmacokinetics of quinolone derivatives in the prostate.

Abstract:

:The pharmacokinetics of six quinolone derivatives were investigated in the human and dog prostate. The possible therapeutic applications of these findings are discussed.

journal_name

Infection

journal_title

Infection

authors

Madsen PO,Aagaard J

doi

10.1007/BF01643687

keywords:

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

S154-6

eissn

0300-8126

issn

1439-0973

journal_volume

19 Suppl 3

pub_type

杂志文章
  • Renin-angiotensin system inhibitors and mortality in patients with COVID-19.

    abstract::Association of renin-angiotensin system inhibitors with risk of death in patients with hypertension (HTN) and coronavirus disease 2019 (COVID-19) is not well characterized. The aim of this study was to evaluate the outcomes of patients with HTN and COVID-19 with respect to different chronic antihypertensive drug intak...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-020-01550-0

    authors: Rossi L,Malagoli A,Biagi A,Zanni A,Sticozzi C,Comastri G,Pannone L,Gandolfi S,Vergara P,Villani GQ

    更新日期:2020-11-22 00:00:00

  • Correction to: Antiretroviral treatment indications and adherence to the German-Austrian treatment initiation guidelines in the German ClinSurv HIV Cohort between 1999 and 2016.

    abstract::In this article the cooperating partners of the ClinSurv HIV cohort were not listed in the acknowledgements. The correct paragraph appears below. ...

    journal_title:Infection

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s15010-019-01281-x

    authors: Stecher M,Schommers P,Schmidt D,Kollan C,Gunsenheimer-Bartmeyer B,Lehmann C,Platten M,Fätkenheuer G,Vehreschild JJ,ClinSurv Study Group.

    更新日期:2019-04-01 00:00:00

  • Bactericidal activity of ciprofloxacin, norfloxacin and ofloxacin in serum and urine after oral administration to healthy volunteers.

    abstract::A 200 mg oral dose of ciprofloxacin, norfloxacin or ofloxacin was administered to six healthy male volunteers in a three way cross-over study in order to examine the kinetics in humans in relation to the bactericidal activity in serum and urine. Serum concentrations for ciprofloxacin were similar to norfloxacin and lo...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01650502

    authors: Zeiler HJ,Beermann D,Wingender W,Förster D,Schacht P

    更新日期:1988-01-01 00:00:00

  • Prophylactic chemotherapy with fosfomycin trometamol during transurethral surgery and urological manoeuvres. Results of a multicentre study.

    abstract::The aim of the present open prospective study is to evaluate the efficacy and safety profile of fosfomycin trometamol in the chemoprophylaxis of urinary tract infections following transurethral diagnostic and/or therapeutic manoeuvres. 712 patients were enrolled in 72 urological surgical centres. All the enrolled pati...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1007/BF01643436

    authors: di Silverio F,Ferrone G,Carati L

    更新日期:1990-01-01 00:00:00

  • Acinetobacter septicemia: a threat to neonates? Special aspects in a neonatal intensive care unit.

    abstract::Acinetobacter is one of the organisms responsible for nosocomial infections in intensive care, neurosurgery, burn and hemodialysis units. There are only a few reports on Acinetobacter infections in neonatal intensive care units. Over a 31 month period, nine cases of Acinetobacter sepsis occurred in our unit, with four...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01728921

    authors: Regev R,Dolfin T,Zelig I,Givoni S,Wolach B

    更新日期:1993-11-01 00:00:00

  • Campylobacter Enteritis.

    abstract::Campylobacter jejuni (previously called "related vibrio") has recently become recognized as an important cause of acute diarrhoeal disease in many countries. As with other intestinal pathogens, the clinical picture of C. jejuni infection varies from symptomless excretion to severe disease. The incubation period averag...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01640857

    authors: Butzler JP

    更新日期:1982-01-01 00:00:00

  • Anti-V3 loop spectrotype in HIV-infected individuals during zidovudine therapy.

    abstract::In order to investigate the role played by zidovudine (ZDV) as immune modulator, particularly on B-cell response, the anti-V3 loop spectrotype in 115 sera from 26 HIV-infected individuals was evaluated, prior to and during treatment with ZDV, by isoelectric focusing and reverse blotting (IEF-RB), a technique useful fo...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01781097

    authors: Biselli R,Del Bono V,Anselmo M,Canessa A,Mazzarello G,D'Amelio R,Bassetti D

    更新日期:1996-05-01 00:00:00

  • A case of Capnocytophaga canimorsus sacral abscess in an immunocompetent patient.

    abstract::We report a unique case of sacral Capnocytophaga canimorsus abscess successfully treated with surgery and antibiotics. Close contact to a dog was assumed to be the most likely source of infection. Established risk factors for invasive C. canimorsus infection such as splenectomy, alcoholism or overt immunosuppression c...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-014-0681-6

    authors: Joswig H,Gers B,Dollenmaier G,Heilbronner R,Strahm C

    更新日期:2015-04-01 00:00:00

  • Disseminated zoster in an elderly patient.

    abstract::A 97-year-old lady was hospitalized for left leg cellulitis. Comorbidity included hypertension and congestive heart failure. While in hospital, she developed a painless vesicular rash localized to the territory of the left trigeminal nerve (third branch), which evolved to pustules and crusts (Figure 1). A chickenpox-l...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-008-8287-5

    authors: Capron J,Steichen O

    更新日期:2009-04-01 00:00:00

  • Antibacterial activity and kill kinetics of amoxicillin-clavulanic acid combinations against Escherichia coli and Klebsiella aerogenes.

    abstract::Combinations of amoxicillin and clavulanic acid were tested against 11 Escherichia coli strains and five Klebsiella aerogenes strains. Apart from one E. coli, the strains were highly resistant to amoxicillin due to beta-lactamase production. Synergy was demonstrated in all strains by agar dilution. Synergy was detecte...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641359

    authors: Fuglesang JE,Bergan T

    更新日期:1983-11-01 00:00:00

  • The effects of ciprofloxacin on human chondrocytes in cell culture.

    abstract::Ciprofloxacin is a highly potent antibacterial agent that is used extensively in bone and joint infections. Because of reports of potential chondro-toxicity in animals, the effects of this drug on cells derived from human cartilage were tested in liquid micromass and agarose gel cultures. An inhibition of cell prolife...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01713325

    authors: Mont MA,Mathur SK,Frondoza CG,Hungerford DS

    更新日期:1996-03-01 00:00:00

  • Investigation on renal tolerability of ciprofloxacin with tests based on monoclonal antibodies.

    abstract::The results obtained during the investigation on the excretion of nine urinary antigens originating in the kidney and characterized by monoclonal antibodies and of the brush-border marker-enzyme alanine aminopeptidase in the urine of 12 volunteers before and during the administration of therapeutic doses of ciprofloxa...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01650513

    authors: Falkenberg FW,Mondorf AW

    更新日期:1988-01-01 00:00:00

  • Peripheral oxygen availability within skeletal muscle in sepsis and septic shock: comparison to limited infection and cardiogenic shock.

    abstract::In 40 intensive care patients, tissue oxygen partial pressure distribution within skeletal muscle was measured in order to estimate peripheral oxygen availability. In septic patients with multiple organ failure (n = 20) mean skeletal muscle pO2 was abnormally high (48.8 +/- 8.5 mmHg, p less than 0.001) in contrast to ...

    journal_title:Infection

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF01645355

    authors: Boekstegers P,Weidenhöfer S,Pilz G,Werdan K

    更新日期:1991-09-01 00:00:00

  • Ceftizoxime (FK 749) in vitro antibacterial activity.

    abstract::The minimal inhibitory concentrations of ceftizoxime, cefotaxime, moxalactam, cefoperazone, cefotiam and cefamandole were determined against various species of gram-negative bacteria and against Staphylococcus aureus. Ceftizoxime was more active against Enterobacteriaceae than cefamandole, cefotiam and cefoperazone an...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641024

    authors: Husson MO,Courcol R,Izard D,Leclerc H

    更新日期:1984-01-01 00:00:00

  • Phlebitis rate and time kinetics of short peripheral intravenous catheters.

    abstract:BACKGROUND:An observational prospective cohort study was carried out on complication rates and time kinetics of phlebitis caused by short peripheral intravenous catheters (PIVCs) in inpatients on 15 hospital wards in four hospitals in Cologne, Germany. PATIENTS AND METHODS:We observed 1,582 patients with 2,495 PIVCs d...

    journal_title:Infection

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s15010-004-1037-4

    authors: Grüne F,Schrappe M,Basten J,Wenchel HM,Tual E,Stützer H,Cologne Quality Control Network.

    更新日期:2004-02-01 00:00:00

  • The binding of Chlamydia trachomatis and zinc to McCoy cells (mouse fibroblasts).

    abstract::Zinc was found to have profoundly different effects upon the infection of McCoy cells (mouse fibroblasts) by two strains of Chlamydia trachomatis dependent upon the time and concentration of zinc exposure. Radiolabeled zinc-65 became McCoy cell-associated in a manner independent of incubation temperature, but highly d...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01646116

    authors: Sugarman B,Agbor P

    更新日期:1987-01-01 00:00:00

  • Interobserver agreement on signs and symptoms of patients with acute febrile illness.

    abstract:PURPOSE:To assess the interobserver agreement on clinical history and physical examination when using a semi-structured questionnaire to evaluate patients with an acute febrile illness (AFI). METHODS:A cross-sectional study was conducted with outpatients aged 12 years and over, presenting with an AFI defined as fever ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0101-0

    authors: Daumas RP,Brasil P,Bressan CS,Oliveira RV,Carvalho BB,Carneiro DV,Passos SR

    更新日期:2011-04-01 00:00:00

  • Safety and immunogenicity of an inactivated hepatitis A vaccine in children 2 to 5 years old.

    abstract::The reactogenicity and immunogenicity of an inactivated hepatitis A vaccine were assessed. Seventy healthy children aged between 2 and 5 years old, who lacked antibodies against the hepatitis A virus, were enrolled in this study. With a 0-, 1-, and 6-month vaccination schedule, the children received three doses of 360...

    journal_title:Infection

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF01716302

    authors: Arístegui J,Morales JL,Dal-Ré R,González A,Gallego MS,Garrote E

    更新日期:1995-09-01 00:00:00

  • Update on the "Choosing Wisely" initiative in infectious diseases in Germany.

    abstract:PURPOSE:The Choosing Wisely® initiative is an international campaign addressing over- and underuse of diagnostic and therapeutic measures in infectious diseases among others. Since 2016, the German Society for Infectious Diseases (DGI) has constantly designed new items in this regard. Here we report the most recent rec...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-020-01400-z

    authors: Draenert R,Jung N,Choosing Wisely (Klug entscheiden) DGI Working Group.

    更新日期:2020-06-01 00:00:00

  • Short courses of intravenous empirical antibiotic treatment in selected febrile neutropenic children with cancer.

    abstract:BACKGROUND:Since the optimal duration of antibiotic therapy in febrile neutropenic patients is not clear, we evaluated the safety and efficacy of short courses of intravenous antibiotic treatment in selected pediatric cancer patients admitted for fever and neutropenia. PATIENTS AND METHODS:We retrospectively analyzed ...

    journal_title:Infection

    pub_type: 临床试验,杂志文章

    doi:10.1007/s15010-002-2094-1

    authors: Lehrnbecher T,Stanescu A,Kühl J

    更新日期:2002-01-01 00:00:00

  • Ototoxicity and nephrotoxicity of netilmicin.

    abstract::Comparative functional and histological tests were performed in eight groups of ten quinea pigs each, which were administered 50, 75, 100 and 150 mg of netilmicin respecitvely b.i.d. for 29 days, 15 and 25 mg of gentamicin and 50 and 100 mg of amikacin per kg body weight respecitvely b.i.d. and in one control group of...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01638926

    authors: Federspil P

    更新日期:1976-01-01 00:00:00

  • Socioeconomic impact on device-associated infections in limited-resource neonatal intensive care units: findings of the INICC.

    abstract:PURPOSE:To evaluate the impact of country socioeconomic status and hospital type on device-associated healthcare-associated infections (DA-HAIs) in neonatal intensive care units (NICUs). METHODS:Data were collected on DA-HAIs from September 2003 to February 2010 on 13,251 patients in 30 NICUs in 15 countries. DA-HAIs ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0136-2

    authors: Rosenthal VD,Lynch P,Jarvis WR,Khader IA,Richtmann R,Jaballah NB,Aygun C,Villamil-Gómez W,Dueñas L,Atencio-Espinoza T,Navoa-Ng JA,Pawar M,Sobreyra-Oropeza M,Barkat A,Mejía N,Yuet-Meng C,Apisarnthanarak A,International N

    更新日期:2011-10-01 00:00:00

  • Penetration of ampicillin and sulbactam into human costal cartilage.

    abstract::The question of whether ampicillin and sulbactam are able to penetrate sufficiently into costal cartilage tissue was investigated in 21 children undergoing surgery for funnel chest malformations. The concentrations of both compounds were determined in the core and mantle pieces of samples taken 45 min or 120 min after...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01739028

    authors: Meier H,Springsklee M,Wildfeuer A

    更新日期:1994-03-01 00:00:00

  • [Pseudomonas aeruginosa immunoglobulin in experimental pneumonia].

    abstract::A guinea pig model of experimental Pseudomonas aeruginosa pneumonia was used to evaluate factors affecting the efficacy of passive immune therapy with Psomaglobin N, a hyperimmune P. aeruginosa globulin. Animals treated 2 h after infection with a single intravenous infusion of Psomaglobin N, 500 mg/kg, demonstrated 33...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01646124

    authors: Pennington JE,Pier GB

    更新日期:1987-01-01 00:00:00

  • Group B streptococcal disease in infants in the first year of life: a nationwide surveillance study in Japan, 2011-2015.

    abstract:PURPOSE:This study aimed to describe the epidemiology of childhood group B streptococcus (GBS) disease including late late-onset disease (LLOD) and to clinically characterize recurrent cases and twin-sibling cases in Japan. METHODS:We collected information on infants (<1 year of age) with invasive GBS disease and inst...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-017-0995-2

    authors: Matsubara K,Hoshina K,Kondo M,Miyairi I,Yukitake Y,Ito Y,Minami K,Genkawa R

    更新日期:2017-08-01 00:00:00

  • Prolonged application of closed in-line suction catheters increases microbial colonization of the lower respiratory tract and bacterial growth on catheter surface.

    abstract:BACKGROUND:Microorganisms become attracted to polymer surfaces for a number of reasons including positive charge of biomaterial or concentration of nutrients on the biomaterial surface. Many bacteria additionally possess specific receptors for the interaction with extracellular host protein components that adhere on th...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s15010-002-3066-1

    authors: Freytag CC,Thies FL,König W,Welte T

    更新日期:2003-01-01 00:00:00

  • Partial in vivo response to corticosteroid treatment in common variable immune deficiency.

    abstract::The case of a 13-year-old girl with CVI is presented who required steroid treatment for myositis. After three weeks of treatment, the serum IgM level increased about ten-fold. Specific antibodies to vaccination antigens, which despite adequate vaccination were absent prior to any kind of treatment, could be synthesize...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01643615

    authors: Wahn V,Grosse-Wilde H,Rosin H,Carls C,Göbel U

    更新日期:1985-01-01 00:00:00

  • In vitro testing of clarithromycin in combination with ethambutol and rifampicin against Mycobacterium avium complex.

    abstract::The activity of clarithromycin in combination with ethambutol and rifampicin was tested at concentrations achievable in serum against 20 strains of Mycobacterium avium complex. The combination of clarithromycin plus rifampicin showed inhibition of 11 of the strains and bactericidal synergism against seven of the strai...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01645362

    authors: Stauffer F,Dörtbudak O,Lahonik E

    更新日期:1991-09-01 00:00:00

  • Is aciclovir prophylaxis necessary after bone marrow transplantation?

    abstract::To assess the cost-effect relationship of aciclovir prophylaxis versus early treatment, we performed a retrospective study in 44 allogeneic bone marrow transplant recipients, who had only received aciclovir for therapeutic purposes. After bone marrow transplantation 18 herpes simplex infections occurred in 15 of the 3...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01643475

    authors: Sinnige LG,van der Meer JW,Gratama JW,Versteeg J,Zwaan FE

    更新日期:1986-05-01 00:00:00

  • [The antibacterial efficacy of cefaclor in routine testing of clinical material from two Berlin hospitals (author's transl)].

    abstract::The agar diffusion method was used to test the antibacterial efficacy of cefaclor against bacterial strains isolated routinely from patients in two hospitals in Berlin. A comparison was made with the efficacy of oxacillin, azlocillin, amikacin, gentamicin, ampicillin, co-trimoxazole, tetracycline, penicillin, cefazoli...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01659732

    authors: Wagner J,Hahn H

    更新日期:1979-01-01 00:00:00