In vitro testing of clarithromycin in combination with ethambutol and rifampicin against Mycobacterium avium complex.

Abstract:

:The activity of clarithromycin in combination with ethambutol and rifampicin was tested at concentrations achievable in serum against 20 strains of Mycobacterium avium complex. The combination of clarithromycin plus rifampicin showed inhibition of 11 of the strains and bactericidal synergism against seven of the strains. When ethambutol was added, a bactericidal effect was observed against 16 strains. On the basis of these in vitro data it seems that clarithromycin in combination with rifampicin and ethambutol may be a promising drug for the effective treatment of infections caused by M. avium complex.

journal_name

Infection

journal_title

Infection

authors

Stauffer F,Dörtbudak O,Lahonik E

doi

10.1007/BF01645362

subject

Has Abstract

pub_date

1991-09-01 00:00:00

pages

343-5

issue

5

eissn

0300-8126

issn

1439-0973

journal_volume

19

pub_type

杂志文章
  • Vaccination against pandemic H1N1 (2009) in patients after allogeneic hematopoietic stem cell transplantation: a retrospective analysis.

    abstract:PURPOSE:Limited data are available on immunologic responses to primary pandemic H1N1 (2009) vaccination in recipients of allogeneic hematopoietic stem cell transplantation (HSCT) recipients. In 2009 serologic responses to either pandemic H1N1 (2009) vaccine (n = 36) or pandemic H1N1 (2009) infection (n = 2) were studie...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0206-5

    authors: Roll D,Ammer J,Holler B,Salzberger B,Schweiger B,Jilg W,Andreesen R,Edinger M,Wolff D,Holler E

    更新日期:2012-04-01 00:00:00

  • The effects of ciprofloxacin on human chondrocytes in cell culture.

    abstract::Ciprofloxacin is a highly potent antibacterial agent that is used extensively in bone and joint infections. Because of reports of potential chondro-toxicity in animals, the effects of this drug on cells derived from human cartilage were tested in liquid micromass and agarose gel cultures. An inhibition of cell prolife...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01713325

    authors: Mont MA,Mathur SK,Frondoza CG,Hungerford DS

    更新日期:1996-03-01 00:00:00

  • Effective treatment of urinary tract infections.

    abstract::In prescribing any particular antimicrobial agent for the treatment of urinary tract infection decisions have to be made on the choice of drug, on the basis of bacteriological findings, the dosage and the duration of administration. These problems are reviewed below in conjunction with the criteria of successful thera...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644939

    authors: Acar JF

    更新日期:1980-01-01 00:00:00

  • Effect of pH on the in vitro activity of and propensity for emergence of resistance to fluoroquinolones, macrolides, and a ketolide.

    abstract::Antibiotic activity against common respiratory pathogens can be affected by the pH of the medium (in vitro) or the bodily fluid (in vivo) in which bacteria are present. The ionized fraction of an antibiotic is not able to efficiently penetrate bacterial or mammalian membranes, reducing the quantity of molecules able t...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-005-8206-y

    authors: Dalhoff A,Schubert S,Ullmann U

    更新日期:2005-12-01 00:00:00

  • Thrombogenicity testing of central venous catheters in vitro.

    abstract::To date there have been no standard methods for assessing the thrombogenicity of central venous catheters. A procedure for testing the thrombogenicity of intravenous lines such as the silver-impregnated catheter by continuous blood flow in vitro was therefore developed. For this test, fresh blood was drawn from health...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF02561614

    authors: Böswald M,Lugauer S,Bechert T,Greil J,Regenfus A,Guggenbichler JP

    更新日期:1999-01-01 00:00:00

  • The course of cryptococcal capsular polysaccharide antigenemia/human cryptococcal polysaccharide elimination kinetics.

    abstract::The detection of cryptococcal polysaccharides in the serum is diagnostic of cryptococcosis in the absence of rheumatoid factor. The significance of the continued detection of this antigen in the serum during antifungal therapy is not known. Prolonged antigenemia might indicate ongoing active infection, delayed clearan...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641291

    authors: Eng R,Chmel H,Corrado M,Smith SM

    更新日期:1983-05-01 00:00:00

  • Pseudomonas vesicularis bacteraemia.

    abstract::A case of repeated episodes of Pseudomonas vesicularis bacteraemia, in a 54-year-old woman with a past history including systemic lupus erythematosus and chronic active autoimmune hepatitis is reported. She was treated with tobramycin and ceftazidime but bacteraemia persisted until surgical resection of the infected t...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01710687

    authors: Planes AM,Ramirez A,Fernandez F,Capdevila JA,Tolosa C

    更新日期:1992-11-01 00:00:00

  • Effect of dexamethasone and pentoxifylline in combination with amoxicillin in the treatment of penicillin-insensitive pneumococcal pneumonia in guinea pigs.

    abstract::A fatal guinea pig model of pneumococcal pneumonia was developed in order to evaluate the efficacy of amoxicillin combined with either pentoxifylline or dexamethasone. Parameters assessed were survival time and lung changes (alterations, bacterial colony counts, inducible nitric oxide synthase [iNOS] and cyclooxygenas...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-002-2098-x

    authors: Parra A,García-Olmos M,Nieto E,García-Calvo G,Ponte C,Soriano F

    更新日期:2002-06-01 00:00:00

  • Ventriculitis caused by Klebsiella pneumoniae successfully treated with pefloxacin in a neonate.

    abstract::Pefloxacin was applied to a newborn suffering from ventriculitis caused by Klebsiella pneumoniae after failure of routine antibiotics. Treatment was successful. Blood and CSF levels were high, thus documenting good CSF penetration. In addition to this case report, a review of the literature regarding seven neonates wi...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01716707

    authors: Linder N,Dagan R,Kuint J,Keler N,Keren G,Reichman B

    更新日期:1994-05-01 00:00:00

  • Infectious keratitis and orthokeratology lens use: a systematic review.

    abstract:PURPOSE:Myopia is a prevalent condition among Asians. Orthokeratology lens has gained popularity as a method of myopia control. This systematic review is to summarize the clinical profile of infectious keratitis in association with orthokeratology lens wear. METHODS:We searched in the PubMed and EMBASE for articles ad...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-017-1023-2

    authors: Kam KW,Yung W,Li GKH,Chen LJ,Young AL

    更新日期:2017-12-01 00:00:00

  • Actinobacillus actinomycetem-comitans endocarditis in a child with a prosthetic heart valve.

    abstract::The first case of Actinobacillus actinomycetem-comitans endocarditis in a child with a prosthetic cardiac valve is reported. Endocarditis was possibly caused by dental work done without antibiotic prophylaxis four weeks prior to admission. ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01645955

    authors: Felius A,Fleer A,Moulaert A

    更新日期:1984-07-01 00:00:00

  • The respiratory pathology in infants with sudden unexpected deaths in whom respiratory specimens were initially PCR-positive or PCR-negative for Bordetella pertussis.

    abstract:BACKGROUND:In a previous controlled study, we investigated the relationship between Bordetella pertussis infections and sudden unexpected deaths among German infants (sudden infant death syndrome, SIDS). In this present study, we investigated further the respiratory pathology in a subset of infants in the original stud...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0164-y

    authors: Cherry JD,Paddock CD,Greer PW,Heininger U

    更新日期:2011-12-01 00:00:00

  • Cerebrospinal fluid glucose levels and sensorineural hearing loss in bacterial meningitis.

    abstract:BACKGROUND:Low cerebrospinal fluid (CSF) glucose levels have been associated with sensorineural hearing loss (SNHL) in bacterial meningitis but systematic investigations are lacking. PATIENTS AND METHODS:A retrospective case control study was conducted comparing CSF glucose levels in 47 cases with and 145 controls wit...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-003-3208-0

    authors: Eisenhut M,Meehan T,Batchelor L

    更新日期:2003-08-01 00:00:00

  • Immunoglobulin prophylaxis against hepatitis A among Swedish UN soldiers in an endemic region.

    abstract::Six hundred and fifteen Swedish soldiers (X = 24.9 years) serving with the UN forces in Cyprus were tested for antibody against hepatitis A (anti-HAV) before and after six months' service. Before the service, a high susceptibility to hepatitis A was found, as only 2.3% (14/615) had anti-HAV. In comparison, the prevale...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01648930

    authors: Weiland O,Berg JV,Bäck E,Lundbergh P

    更新日期:1979-01-01 00:00:00

  • New fluoroquinolones in lower respiratory tract infections and emerging patterns of pneumococcal resistance.

    abstract::The increasing resistance of Streptococcus pneumoniae, the most important community respiratory pathogen, to beta-lactams and other first-line antimicrobial agents usually employed for the empirical treatment of lower respiratory tract infections has led to the inclusion, in several current guidelines, of a fluoroquin...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-005-4102-8

    authors: Ferrara AM

    更新日期:2005-06-01 00:00:00

  • Haemophilus aphrophilus meningitis complicated by hydrocephalus in an immunocompetent adult.

    abstract::A case of meningitis due to an unusual organism, Haemophilus aphrophilus in an adult is described. In spite of rapid clearance of the organism from the cerebrospinal fluid with intravenous cefotaxime, fever persisted over 8 days of therapy and infection was complicated by hydrocephalus. H. aphrophilus meningitis is un...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF02770846

    authors: Adeyemi-Doro FA,Hui AC,Ho FN,Ip M

    更新日期:1998-11-01 00:00:00

  • Synchronous multifocal necrotizing fasciitis prognostic factors: a retrospective case series study in a single center.

    abstract:PURPOSE:No reports have been published on synchronous multifocal necrotizing fasciitis (SMNF), a multifocal presence of necrotizing fasciitis in different extremities. We evaluated the clinical characteristics and outcomes of SMNF. METHODS:Eighteen patients (14 men, 4 women; mean age: 59 years) diagnosed with SMNF of ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-016-0932-9

    authors: Lee CY,Li YY,Huang TW,Huang TY,Hsu WH,Tsai YH,Huang JC,Huang KC

    更新日期:2016-12-01 00:00:00

  • Passive immunization against cytomegalovirus in allograft recipients. The Rotterdam Heart Transplant Program experience.

    abstract::We analyzed the results of passive immunization against CMV in 146 heart transplant recipients. The 65 seronegative recipients were prophylactically treated with anti-CMV immunoglobulins during and after the operation. Twenty-nine of these 65 patients received a seropositive donor heart. CMV infection occurred in 21/6...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01728886

    authors: Balk AH,Weimar W,Rothbarth PH,Meeter K,Metselaar HJ,Mochtar B,Simoons ML

    更新日期:1993-07-01 00:00:00

  • [A microbiological method for the rapid determination of antibiotic concentrations during therapy (author's transl)].

    abstract::The assay described is an agar diffusion test using Bacillus stearothermophilus as test organism. Incubation is at 62 degrees C; results can be obtained rapidly within 2 to 3 hours. The test was developed for the determination of gentamicin concentrations in serum and other body fluids. Because of its high sensitivity...

    journal_title:Infection

    pub_type: 杂志文章

    doi:

    authors: Wahlig H

    更新日期:1977-01-01 00:00:00

  • Burrowing bug pigmentation.

    abstract::Cydnidae bug (also termed the burrowing bug) are arthropods of the order Hemiptera, that are recognized by their morphological adaptations for digging. They release an odorous substance from special glands that serve as self-defense, causing pigmented macules when in contact with human skin, especially during the rain...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-020-01481-w

    authors: Chakraborty S,Sil A,Panigrahi A

    更新日期:2020-07-11 00:00:00

  • Clinical significance of Bacteroidaceae.

    abstract::Material from 50 patients with purulent otitis media was investigated. All patients had undergone surgical operation. The results indicate that anaerobic non spore-forming bacteria, especially gram-negative rods of the family Bacteroidaceae, may play an important role in the aetiology of purulent otitis media. In a fu...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01639899

    authors: Hudác A

    更新日期:1980-01-01 00:00:00

  • Non-typeable Haemophilus influenzae-associated early pregnancy loss: an emerging neonatal and maternal pathogen.

    abstract:OBJECTIVES:There is increasing evidence indicating an association between invasive non-typeable Haemophilus influenzae (NTHi) infection in pregnancy and early pregnancy loss. As the diagnosis relies on microbiological investigation of post-mortem placental and foetal samples, a significant proportion of NTHi-related pr...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-019-01359-6

    authors: Cevik M,Moncayo-Nieto OL,Evans MJ

    更新日期:2020-04-01 00:00:00

  • Oxacillin-susceptible methicillin-resistant Staphylococcus aureus (OS-MRSA), a hidden resistant mechanism among clinically significant isolates in the Wessex region/UK.

    abstract:PURPOSE:Methicillin-resistant Staphylococcus aureus (MRSA) is defined as S. aureus genetically having the mecA or mecC genes or phenotypically showing minimum inhibitory concentration (MIC) of oxacillin higher than 2 mg/L. However, recently, cefoxitin/oxacillin-susceptible mecA-positive S. aureus (OS-MRSA) has been rep...

    journal_title:Infection

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s15010-014-0641-1

    authors: Saeed K,Ahmad N,Dryden M,Cortes N,Marsh P,Sitjar A,Wyllie S,Bourne S,Hemming J,Jeppesen C,Green S

    更新日期:2014-10-01 00:00:00

  • Transintestinal elimination of ciprofloxacin in humans--concomitant assessment of its metabolites in serum, ileum and colon.

    abstract::Ciprofloxacin (200 mg) was infused to seven patients at the beginning of elective colorectal surgery. Thirty minutes after the end of infusion (i.e. 60 min after the start of the operation) ciprofloxacin reached concentrations of 1.60 mg/l in serum and of 3.42-6.07 mg/kg fresh weight in the ileum and colon. During the...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01710676

    authors: Viell B,Krause B,Vestweber KH,Schaaf S,Scholl H

    更新日期:1992-11-01 00:00:00

  • Comparative trial of trimethoprim and co-trimoxazole in recurrent urinary infections.

    abstract::Eighty-nine patients with a history of recurrent urinary infection who required immediate treatment for significant bacteriuria were treated with either trimethoprim (300 mg at night) or with the standard course of co-trimoxazole (two tablets 12-hourly) for seven days. Cure rates one week after the end of treatment we...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01640874

    authors: Brumfitt W,Hamilton-Miller JM,Ludlam H,Damjanovic V,Gargan R

    更新日期:1982-09-01 00:00:00

  • Lymphocyte apoptosis, caspase activation and inflammatory response in septic shock.

    abstract:BACKGROUND:We examined lymphocyte apoptosis, activity of caspases-1, -3, -8 and -9 and the relationship between those two events and inflammation response in septic shock. MATERIALS AND METHODS:Blood samples were obtained within 24 h after diagnosis of septic shock from 16 patients to measure apoptosis, caspases-3, -8...

    journal_title:Infection

    pub_type: 信件

    doi:10.1007/s15010-008-7070-y

    authors: Delogu G,Famularo G,Tellan G,Marandola M,Antonucci A,Signore M,Marcellini S,Moretti S

    更新日期:2008-10-01 00:00:00

  • [Effectiveness and tolerance of cefixime in bacterial infections in the ENT area].

    abstract::Clinical efficacy and tolerance of cefixime were investigated in an open, uncontrolled trial. 200 mg of cefixime were applied twice daily, duration of therapy was between eight and 14 days (mean value 10.1 days, standard deviation +/- 1.4 days). Ten male patients (mean age 42.7 years) and 19 female patients (mean age ...

    journal_title:Infection

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF01644629

    authors: Theopold M,Benner U,Bauernfeind A

    更新日期:1990-01-01 00:00:00

  • Correction to: Clinical management of ageing people living with HIV in Europe: the view of the care providers.

    abstract::The original version of this article unfortunately contained a mistake. ...

    journal_title:Infection

    pub_type: 已发布勘误

    doi:10.1007/s15010-020-01463-y

    authors: Boffito M,Ryom L,Spinner C,Martinez E,Behrens G,Rockstroh J,Hohenauer J,Lacombe K,Psichogyiou M,Voith N,Mallon P,Branco T,Svedhem V,dÁrminio Monforte A

    更新日期:2020-08-01 00:00:00

  • Qualitative and quantitative microbiological analysis of sputa of 102 patients with cystic fibrosis.

    abstract::A microbiological analysis of 102 patients suffering from cystic fibrosis was conducted over a 22 month period. 20 microbial species with the following incidence were identified: Pseudomonas aeruginosa: 83.4%; Candida albicans: 29.4%; Staphylococcus aureus: 24.5%; Staphylococcus epidermidis: 11.8%; Haemophilus influen...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644137

    authors: Bauernfeind A,Bertele RM,Harms K,Hörl G,Jungwirth R,Petermüller C,Przyklenk B,Weisslein-Pfister C

    更新日期:1987-07-01 00:00:00

  • Temporofacial zygomycosis in a pregnant woman.

    abstract::A 38-year-old Omani woman, seven months pregnant, developed extensive zygomycosis involving maxillary and temporal bones. No evidence of any underlying immune deficiency was detected except that which may be attributed to pregnancy. After delivery the patient was treated with repeated courses of amphotericin B, which ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF02033066

    authors: Buhl MR,Joseph TP,Snelling BE,Buhl L

    更新日期:1992-07-01 00:00:00