Comparative trial of trimethoprim and co-trimoxazole in recurrent urinary infections.

Abstract:

:Eighty-nine patients with a history of recurrent urinary infection who required immediate treatment for significant bacteriuria were treated with either trimethoprim (300 mg at night) or with the standard course of co-trimoxazole (two tablets 12-hourly) for seven days. Cure rates one week after the end of treatment were 74.4% and 80.4%, respectively. During the following month the relapse rate was lower in the group given trimethoprim than among those who had received co-trimoxazole. Consequently, the cure rates six weeks after the start of treatment were 71.4% in the trimethoprim group and 58.5% in the co-trimoxazole group. These results suggest that in this type of patient, it may be possible to reduce the incidence of bacteriological relapse by giving antibiotics in larger doses and at less frequent intervals than are at present generally recommended.

journal_name

Infection

journal_title

Infection

authors

Brumfitt W,Hamilton-Miller JM,Ludlam H,Damjanovic V,Gargan R

doi

10.1007/BF01640874

subject

Has Abstract

pub_date

1982-09-01 00:00:00

pages

280-4

issue

5

eissn

0300-8126

issn

1439-0973

journal_volume

10

pub_type

临床试验,杂志文章,随机对照试验
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    pub_type: 杂志文章

    doi:10.1007/BF01640866

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    更新日期:1982-01-01 00:00:00

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  • Guillain-Barré syndrome associated with autochthonous infection by hepatitis E virus subgenotype 3c.

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    journal_title:Infection

    pub_type: 杂志文章

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    authors: Scharn N,Ganzenmueller T,Wenzel JJ,Dengler R,Heim A,Wegner F

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    pub_type: 杂志文章

    doi:10.1007/BF01642766

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    更新日期:1975-01-01 00:00:00

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    pub_type: 杂志文章

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  • The influence of maternally derived antibody on the efficacy of further attenuated measles vaccine.

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    pub_type: 杂志文章

    doi:10.1007/BF01642310

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    更新日期:1978-01-01 00:00:00

  • Guidelines for medical research in children.

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    pub_type: 杂志文章,评审

    doi:10.1007/BF01645562

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    更新日期:1989-11-01 00:00:00

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641022

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    更新日期:1984-01-01 00:00:00

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    pub_type: 杂志文章

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    pub_type: 杂志文章

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    pub_type: 杂志文章,多中心研究

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    更新日期:1999-01-01 00:00:00

  • Ventriculitis caused by Klebsiella pneumoniae successfully treated with pefloxacin in a neonate.

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    pub_type: 杂志文章,评审

    doi:10.1007/BF01716707

    authors: Linder N,Dagan R,Kuint J,Keler N,Keren G,Reichman B

    更新日期:1994-05-01 00:00:00

  • Penetration of ampicillin and sulbactam into human costal cartilage.

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    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

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    更新日期:1994-03-01 00:00:00

  • Clinical significance of Bacteroidaceae.

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    pub_type: 杂志文章

    doi:10.1007/BF01639899

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    更新日期:1980-01-01 00:00:00

  • Secretory non-pancreatic phopholipase A2 in severe sepsis: relation to endotoxin, cytokines and thromboxane B2.

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    pub_type: 杂志文章

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    更新日期:1996-03-01 00:00:00

  • A retrospective analysis of weight changes in HIV-positive patients switching from a tenofovir disoproxil fumarate (TDF)- to a tenofovir alafenamide fumarate (TAF)-containing treatment regimen in one German university hospital in 2015-2017.

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  • Mycobacterium kansasii pericarditis as a presentation of AIDS.

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  • In vitro activity of clarithromycin and its 14-hydroxy-metabolite against 203 strains of Haemophilus influenzae.

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    pub_type: 杂志文章

    doi:10.1007/BF01704612

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    更新日期:1992-05-01 00:00:00

  • In vitro susceptibility of anaerobes to co-trimoxazole.

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    pub_type: 杂志文章

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    更新日期:1980-01-01 00:00:00

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    journal_title:Infection

    pub_type: 社论

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    更新日期:2019-02-01 00:00:00

  • Thyroiditis due to Brucella melitensis--report of two cases.

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    pub_type: 杂志文章

    doi:10.1007/BF01642110

    authors: von Graevenitz A,Colla F

    更新日期:1990-05-01 00:00:00

  • Pancreatic tuberculosis mimicking pancreatic head carcinoma: a case report and review of the literature.

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    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01739920

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    更新日期:1994-07-01 00:00:00

  • Anaerobic microbiology in the NASA space program.

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01639903

    authors: Brewer JH

    更新日期:1980-01-01 00:00:00

  • Rotavirus epidemiology and vaccine demand: considering Bangladesh chapter through the book of global disease burden.

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    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-017-1082-4

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    更新日期:2018-02-01 00:00:00

  • Staphylococcus aureus meningitis in adults: a clinical comparison of infections caused by methicillin-resistant and methicillin-sensitive strains.

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-001-1092-z

    authors: Chang WN,Lu CH,Wu JJ,Chang HW,Tsai YC,Chen FT,Chien CC

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    pub_type: 杂志文章

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-007-6108-x

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    更新日期:2007-10-01 00:00:00

  • Correction to: Time‑trend population analysis of the clinical and epidemiologic effect on pediatric infective endocarditis after change of antibiotic prophylaxis guidelines.

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    pub_type: 已发布勘误

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    authors: Knirsch W,Schuler SK,Christmann M,Weber R

    更新日期:2020-10-01 00:00:00