Guillain-Barré syndrome associated with autochthonous infection by hepatitis E virus subgenotype 3c.

Abstract:

:In this report, we present a case of a 50-year-old immunocompetent man with Guillain-Barré syndrome (GBS) associated with an autochthonous hepatitis E virus (HEV) infection. The patient presented with tetraparesis and elevated liver enzymes. HEV infection was confirmed serologically and by polymerase chain reaction (PCR) from blood and stool. Phylogenetic analysis revealed a novel HEV genotype 3 isolate closely related to other subgenotype 3c isolates from pig livers purchased in Germany. This indicates an autochthonous, potentially food-related hepatitis E and is, to our knowledge, the first report about a neurological syndrome associated with an HEV subgenotype 3c infection.

journal_name

Infection

journal_title

Infection

authors

Scharn N,Ganzenmueller T,Wenzel JJ,Dengler R,Heim A,Wegner F

doi

10.1007/s15010-013-0448-5

subject

Has Abstract

pub_date

2014-02-01 00:00:00

pages

171-3

issue

1

eissn

0300-8126

issn

1439-0973

journal_volume

42

pub_type

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