Abstract：
:Drug-induced anaphylaxis is an unpredictable adverse reaction. Although it may occur with any medication, antibiotics induce more cases of anaphylaxis than any other medication class with most cases being induced by β-lactam antibiotics. Clindamycin is an antibiotic with good gram-positive and anaerobe coverage which is often used in patients with β-lactam allergies. We report the case of a 46-year-old female who experienced anaphylaxis after a dose of intravenous (IV) clindamycin. Following treatment with methylprednisolone, epinephrine, diphenhydramine, and albuterol, the patient stabilized. The patient's score on the Naranjo's algorithm was 8 (probable); a score of 9 (definite) limited only by absence of drug re-challenge. To our knowledge, this is the first report of a clindamycin-induced anaphylaxis where the patient was not exposed to any other agent that may have triggered the response, the first case in the United States, and only the third documented case in the literature. Clinicians should be aware of the potential for drug-induced anaphylaxis in all medications.
journal_name
Infectionjournal_title
Infectionauthors
Bulloch MN,Baccas JT,Arnold Sdoi
10.1007/s15010-015-0826-2subject
Has Abstractpub_date
2016-06-01 00:00:00pages
357-9issue
3eissn
0300-8126issn
1439-0973pii
10.1007/s15010-015-0826-2journal_volume
44pub_type
杂志文章相关文献
INFECTION文献大全abstract：:The original version of this article unfortunately contained a mistake. In the author list, the first and last names were tagged incorrectly. The corrected author list is given above. ...
journal_title：Infection
pub_type： 已发布勘误
doi：10.1007/s15010-020-01490-9
更新日期：2020-10-01 00:00:00
abstract：:The case of an HIV-infected patient with low CD4+ cell count and localized pulmonary infection associated with Mycobacterium tilburgii, a recently recognized atypical mycobacterial species, is reported. Diagnosis was confirmed by repeated detection of mycobacterial DNA in lung biopsy specimens. After surgical removal ...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-005-4118-0
更新日期：2005-08-01 00:00:00
abstract：PURPOSE:To test a new assay based on an ex vivo cytokine release from whole blood for the monitoring of immune changes in human immunodeficiency virus (HIV)-infected patients. METHODS:A pilot study of outpatients with HIV infection (n = 9) at a large academic hospital who were divided into three groups: HIV-infected p...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-013-0445-8
更新日期：2013-06-01 00:00:00
abstract：:Intestinal microsporidiosis with Enterocytozoon bieneusi was diagnosed in three of 18 HIV-infected patients with chronic diarrhoea. In two cases all known stages of the life cycle of E. bieneusi (merogonial plasmodia, sporogonial plasmodia, sporoblasts, spores) were found in duodenal biopsies by electron microscopical...
journal_title：Infection
pub_type： 杂志文章,评审
doi：10.1007/BF01715501
更新日期：1994-11-01 00:00:00
abstract：BACKGROUND:Current data on the risk of transmission of 2009 H1N1 Influenza in public transportation systems (e.g., public trains, busses, airplanes) are conflicting. The main transmission route of this virus is thought to be via droplets, but airborne transmission has not been completely ruled out. METHODS:This is a c...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-011-0084-x
更新日期：2011-04-01 00:00:00
abstract：:The purpose of this study was to determine the effectiveness and tolerability of norfloxacin, cinoxacin and oxolinic acid in the treatment of urinary tract infections (UTI) in comparison to nalidixic acid. 125 patients were given the drugs in the appropriate doses for 10-14 days and 30 patients were treated for six we...
journal_title：Infection
pub_type： 临床试验,杂志文章
doi：10.1007/BF01645218
更新日期：1984-11-01 00:00:00
abstract：:Influenza viruses type A and B can cause a wide spectrum of illness, and they are responsible for considerable mortality and morbidity. With the new neuraminidase inhibitors, of which zanamivir was the first drug to be licensed, the physician has antivirals at his disposal which are safe and effective against both inf...
journal_title：Infection
pub_type： 杂志文章,评审
doi：10.1007/s150100070016
更新日期：2000-09-01 00:00:00
abstract：BACKGROUND:The diagnostic value of admission serum levels of procalcitonin (PCT) and C-reactive protein (CRP) as indicators of the etiology and prognosis was prospectively investigated. PATIENTS:96 patients, 50-85 years of age, treated in the hospital for community-acquired pneumonia (CAP). RESULTS:On admission, all ...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s150100050049
更新日期：2000-03-01 00:00:00
abstract：:A study on prevention of borreliosis in humans bitten by infected ticks was performed in 1992-1994 in the Perm' region of Russia. Adult Ixodes persulcatus ticks were removed from the study subjects, and live preparations made from the material obtained from the gut of each tick were microscopically analyzed (up to 250...
journal_title：Infection
pub_type： 临床试验,杂志文章
doi：10.1007/BF01713337
更新日期：1996-03-01 00:00:00
abstract：:Serum and sputum concentrations of ampicillin or amoxycillin were measured in patients admitted to hospital for acute exacerbations of chronic bronchitis with purulent sputum. Mean peak serum levels of nearly 12 mg/l were found after 1600 mg bacampicillin (mean peak level in sputum 0.85 mg/l). The serum and sputum con...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/BF01659773
更新日期：1979-01-01 00:00:00
abstract：:The aim of the present open prospective study is to evaluate the efficacy and safety profile of fosfomycin trometamol in the chemoprophylaxis of urinary tract infections following transurethral diagnostic and/or therapeutic manoeuvres. 712 patients were enrolled in 72 urological surgical centres. All the enrolled pati...
journal_title：Infection
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1007/BF01643436
更新日期：1990-01-01 00:00:00
abstract：:The penetration of ampicillin into middle ear effusions after oral administration of 800 mg bacampicillin to patients with acute otitis media was studied and compared with the serum levels. One hour after administration a mean (+/- SEM) concentration of 2.4 +/- 0.4 micrograms/ml ampicillin was found in the effusions a...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/BF01659775
更新日期：1979-01-01 00:00:00
abstract：:A 17-year-old boy presented with a severe form of an acute disseminated encephalomyelitis (ADEM) with hemiparesis and coma after initial symptoms of a flu-like febrile infection 1 week previously. Titers against Mycoplasma pneumoniae were significantly increased in serum and cerebrospinal fluid (CSF). Detection of M. ...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-001-1173-z
更新日期：2001-08-01 00:00:00
abstract：:Until present studies are lacking which investigate the bactericidal activity of new quinolones in body fluids. Therefore, we determined bactericidal titers of enoxacin (en) and ciprofloxacin (cip) against a typical pathogen in urinary tract infections (Escherichia coli) in urine and against a typical pathogen in resp...
journal_title：Infection
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF01643629
更新日期：1989-01-01 00:00:00
abstract：PURPOSE:Data on the systemic dissemination in Staphylococcus aureus bloodstream infection (SAB) remain sparse. We investigated the timing and the sequence of clinical symptoms, diagnostic confirmation, and occurrence of multiple infective foci in relation to three major infective foci. METHODS:From 2006 to 2011, all a...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-018-1165-x
更新日期：2018-10-01 00:00:00
abstract：:Nearly everyone agrees that violations in research occur. Nobody knows how often. But if Pediatrics is to progress children must be the subjects of research carried out in an acceptable way. The following guidelines should be followed in childhood experimentation: (1) Research should not be done on children if the sam...
journal_title：Infection
pub_type： 杂志文章,评审
doi：10.1007/BF01645562
更新日期：1989-11-01 00:00:00
abstract：:A case of meningitis due to an unusual organism, Haemophilus aphrophilus in an adult is described. In spite of rapid clearance of the organism from the cerebrospinal fluid with intravenous cefotaxime, fever persisted over 8 days of therapy and infection was complicated by hydrocephalus. H. aphrophilus meningitis is un...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/BF02770846
更新日期：1998-11-01 00:00:00
abstract：BACKGROUND:This study was undertaken to compare the clinical characteristics of adult methicillin-sensitive Staphylococcus aureus (MSSA) meningitis and adult methicillin-resistant S. aureus (MRSA) meningitis. PATIENTS AND METHODS:The clinical characteristics and therapeutic outcomes of 19 adult patients with S. aureus...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-001-1092-z
更新日期：2001-10-01 00:00:00
abstract：:In most cases of respiratory tract infection, antibiotic therapy has to be initiated before the results of microbiological examination are available. The four most common pathogens of acute exacerbations of chronic bronchitis are pneumococci, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus. Pne...
journal_title：Infection
pub_type： 杂志文章,评审
doi：10.1007/BF01710341
更新日期：1993-01-01 00:00:00
abstract：:A time-dependent degree of immunosuppression or immunostimulation which may be correlated to pharmacokinetic variables was obtained by administering a single dose of ofloxacin, norfloxacin, pipemidic and piromidic acid to healthy volunteers. The plasma samples collected before drug administration and then at various t...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/BF01661284
更新日期：1986-01-01 00:00:00
abstract：BACKGROUND:As the number of AIDS cases increases in India, information available among clinicians about the prevalence of opportunistic infections (OIs) is scarce. The aim of the present study was to document the characteristic OIs of HIV-infected North Indian patients along with their CD4+ counts. PATIENTS AND METHOD...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-003-3198-y
更新日期：2003-10-01 00:00:00
abstract：:Pneumopericardium, the presence of air in the pericardial space, is a rare disorder that is usually caused by trauma. We describe a patient given induction chemotherapy for acute myelogenous leukemia who developed pulmonary aspergillosis that resulted in pericarditis and pneumopericardium. He responded to antifungal t...
journal_title：Infection
pub_type： 杂志文章,评审
doi：10.1007/BF01739015
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND:In recent years, several reports have suggested, but never definitely demonstrated that dental units (DU) could be potential sources of viral cross-infections sustained by viral agents including HBV, HCV and HIV. This work aims at assessing the risk of HCV cross-infection by dental unit water lines (DUWLs). ...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-008-7246-5
更新日期：2008-10-01 00:00:00
abstract：:Ciprofloxacin (200 mg) was infused to seven patients at the beginning of elective colorectal surgery. Thirty minutes after the end of infusion (i.e. 60 min after the start of the operation) ciprofloxacin reached concentrations of 1.60 mg/l in serum and of 3.42-6.07 mg/kg fresh weight in the ileum and colon. During the...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/BF01710676
更新日期：1992-11-01 00:00:00
abstract：:Indwelling urinary catheters play a very important part in urology. However, their use is accompanied by a considerable increase in the risk of nosocomial urinary tract infections. The pathophysiological cause is ascribed to pathogens that adhere to the catheter surface, proliferate and produce a biofilm. In addition ...
journal_title：Infection
pub_type： 杂志文章,评审
doi：10.1007/BF02561624
更新日期：1999-01-01 00:00:00
abstract：:Schistosomiasis is a widespread helminthic infection which sometimes may affect travelers to endemic areas. We report on a case of urogenital and placental schistosomiasis in a 28-year-old German woman who had been exposed to schistosomiasis in Lake Malawi one year earlier. She experienced painless macrohaematuria in ...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-014-0684-3
更新日期：2014-12-01 00:00:00
abstract：PURPOSE:Giving advice about antibiotic prescription through dedicated consultations is a cornerstone of antibiotic stewardship programmes. Our objective was to explore practices, organisation, and regulatory requirements related to antibiotic advising. METHODS:We performed an international, exploratory, Internet-based...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-019-01298-2
更新日期：2019-10-01 00:00:00
abstract：INTRODUCTION:Human herpes virus 6 (HHV6) infection is a self-limiting illness occurring in early childhood. As with other herpes viruses, the encephalopathy associated with HHV6 is often attributable to the reactivation of a virus previously latent in human brain tissue. Previous reports on HHV6 encephalopathy dealt ma...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-012-0295-9
更新日期：2012-10-01 00:00:00
abstract：:A fatal guinea pig model of pneumococcal pneumonia was developed in order to evaluate the efficacy of amoxicillin combined with either pentoxifylline or dexamethasone. Parameters assessed were survival time and lung changes (alterations, bacterial colony counts, inducible nitric oxide synthase [iNOS] and cyclooxygenas...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-002-2098-x
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:In a previous controlled study, we investigated the relationship between Bordetella pertussis infections and sudden unexpected deaths among German infants (sudden infant death syndrome, SIDS). In this present study, we investigated further the respiratory pathology in a subset of infants in the original stud...
journal_title：Infection
pub_type： 杂志文章
doi：10.1007/s15010-011-0164-y
更新日期：2011-12-01 00:00:00
