Prophylactic chemotherapy with fosfomycin trometamol during transurethral surgery and urological manoeuvres. Results of a multicentre study.

Abstract:

:The aim of the present open prospective study is to evaluate the efficacy and safety profile of fosfomycin trometamol in the chemoprophylaxis of urinary tract infections following transurethral diagnostic and/or therapeutic manoeuvres. 712 patients were enrolled in 72 urological surgical centres. All the enrolled patients received an initial dose of fosfomycin trometamol (Monuril sachet containing 3 g of active drug in powder) 3 h before and a second dose 24 h after the transurethral manoeuvres. Clinical and microbiological examinations were carried out before the intervention, and then on the second and seventh days after the manoeuvres. 94 patients with positive baseline tests were excluded from the microbiological follow-up for non-compliance with the main inclusion criteria. Out of 618 patients with sterile urine or with bacteriuria less than 10(5) ml on baseline screening, 20 (3.2%) developed UTI on the second day and 22 (3.6%) on the seventh day after treatment. Clinical follow-up is in agreement with these microbiological data. Overall, a total of 24 side effects were observed (3.3%), 16 of which were associated with Monuril treatment. The results of this open study agree with the preliminary observations in the controlled studies.

journal_name

Infection

journal_title

Infection

authors

di Silverio F,Ferrone G,Carati L

doi

10.1007/BF01643436

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

S98-102

eissn

0300-8126

issn

1439-0973

journal_volume

18 Suppl 2

pub_type

临床试验,杂志文章,多中心研究
  • Short courses of intravenous empirical antibiotic treatment in selected febrile neutropenic children with cancer.

    abstract:BACKGROUND:Since the optimal duration of antibiotic therapy in febrile neutropenic patients is not clear, we evaluated the safety and efficacy of short courses of intravenous antibiotic treatment in selected pediatric cancer patients admitted for fever and neutropenia. PATIENTS AND METHODS:We retrospectively analyzed ...

    journal_title:Infection

    pub_type: 临床试验,杂志文章

    doi:10.1007/s15010-002-2094-1

    authors: Lehrnbecher T,Stanescu A,Kühl J

    更新日期:2002-01-01 00:00:00

  • Assays of cephalosporin antibiotics administered prophylactically in open heart surgery. Determination of serum and tissue levels before, during and after cardiopulmonary bypass.

    abstract::Twenty-eight patients who underwent open-heart surgery were divided into three groups, each of which received a different antibiotic from the cephalosporin series (cephalotin, cefazolin or cefamandole) in order to prevent infection. All antibiotics were given via intravenous infusion in a dosage of 2 g prior to surger...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641087

    authors: Eigel P,Tschirkov A,Satter P,Knothe H

    更新日期:1978-01-01 00:00:00

  • Non-fermentative Gram-negative rods bacteremia in children with cancer: a 14-year single-center experience.

    abstract:PURPOSE:Data on non-fermentative Gram-negative rods (NFGNR) bacteremia in children with malignancies are limited. The aim of this study was to present clinical picture, antimicrobial susceptibility pattern, risk factors for resistance and outcome in NFGNR bacteremia in children with cancer. METHODS:All episodes of NFG...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-017-0988-1

    authors: Averbuch D,Avaky C,Harit M,Stepensky P,Fried I,Ben-Ami T,Temper V,Peled Y,Troen H,Masarwa R,Abu Ahmad W,Weintraub M,Revel-Vilk S,Engelhard D

    更新日期:2017-06-01 00:00:00

  • Correction to: Clinical management of ageing people living with HIV in Europe: the view of the care providers.

    abstract::The original version of this article unfortunately contained a mistake. ...

    journal_title:Infection

    pub_type: 已发布勘误

    doi:10.1007/s15010-020-01463-y

    authors: Boffito M,Ryom L,Spinner C,Martinez E,Behrens G,Rockstroh J,Hohenauer J,Lacombe K,Psichogyiou M,Voith N,Mallon P,Branco T,Svedhem V,dÁrminio Monforte A

    更新日期:2020-08-01 00:00:00

  • Nosocomial pneumonia caused by carbapenem-resistant Raoultella planticola: a case report and literature review.

    abstract::Raoultella planticola is a rare opportunistic pathogen usually invaded immunocompromised patients and sometimes even causes fatal infections. Recently, there is growing concern about the emergence of carbapenem resistance in this species. Here, we describe one case of hospital-acquired pneumonia due to a carbapenem-re...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-015-0722-9

    authors: Xu M,Xie W,Fu Y,Zhou H,Zhou J

    更新日期:2015-04-01 00:00:00

  • Brucellosis: difficulties in diagnosis and a report on 38 cases.

    abstract::We have reviewed 38 patients with brucellosis who were admitted to the Chaim Sheba Medical Center between 1955 and 1977, i.e. during a 23-year period. The clinical manifestations varied greatly. Diagnosis was easy when brucellosis was suspected, as in cases presenting with fever of unknown origin. In nine of the 38 ca...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641353

    authors: Samra Y,Shaked Y,Hertz M,Altman G

    更新日期:1983-11-01 00:00:00

  • Diagnosis and treatment of chlamydial venereal disease.

    abstract::We examined patients attending an STD clinic (Department of Dermatology, Lasarettet, Lund). Chlamydia trachomatis was demonstrated in 26% of 2021 male patients by culture from the urethra (using cyclo-heximide-treated McCoy cells). The corresponding figure for Neisseria gonorrhoeae was 15%. Both organisms were found i...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01640715

    authors: Thelin I

    更新日期:1982-01-01 00:00:00

  • [Ceftazidime versus cefotaxime in the therapy of severe infections in intensive care patients].

    abstract::In a randomized controlled, clinical study the efficacy of ceftazidime at a dosage of 2 g b. i. d. was compared to that of cefotaxime at a dosage of 2 g t. i. d. or more in the treatment of pneumonia or peritonitis in intensive care patients. 61 of 67 assessable cases were evaluable. In the ceftazidime group ten out o...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01645865

    authors: Müller E,Heinkelein J

    更新日期:1987-01-01 00:00:00

  • An outbreak of rubella aboard a ship of the German Navy.

    abstract:BACKGROUND:During May and June 1996, an outbreak of rubella occurred offshore aboard a ship of the German Navy. The outbreak spread among 330 crew members over a period of 9 weeks, ending 2 days after the ship's return. This is the first detailed epidemiological investigation of a rubella outbreak on a ship, describing...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-003-3048-y

    authors: Ziebold C,Hassenpflug B,Wegner-Bröse H,Wegner K,Schmitt HJ

    更新日期:2003-06-01 00:00:00

  • Recommendations for the management of acute hepatitis B: position paper of the Italian Society for the Study of Infectious and Tropical Diseases (SIMIT).

    abstract:PURPOSE:To develop recommendations for the management of acute hepatitis B by the Italian Society for the Study of Infectious and Tropical Diseases. METHODS:Development of the recommendations divided into three levels of evidence according to the GRADE system: A (high), B (medium) and C (low experts opinion), together...

    journal_title:Infection

    pub_type: 杂志文章,实务指引,评审

    doi:10.1007/s15010-014-0642-0

    authors: Bruno R,Carosi G,Coppola N,Gaeta GB,Puoti M,Santantonio T,Taliani G,Armignacco O,Sagnelli E,Andreoni M,Angarano G,Di Perri G,D'Offizi G,Galli M,Rizzardini G,Italian Society for the Study of Infectious and Tropical Diseases.

    更新日期:2014-10-01 00:00:00

  • Ciprofloxacin concentrations in tonsils following a single intravenous infusion.

    abstract::Penetration of ciprofloxacin into human tonsils was studied following an intravenous infusion of 200 mg over 15 minutes to adult humans undergoing tonsillectomy. Samples were taken one-and-a-half to four hours after dosing. Generally, tissue levels exceeded corresponding serum concentrations by 50% (range of intraindi...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01651152

    authors: Falser N,Dalhoff A,Weuta H

    更新日期:1984-09-01 00:00:00

  • Concentration of ciprofloxacin in bone tissue after single parenteral administration to patients older than 70 years.

    abstract::The concentrations of ciprofloxacin produced in bone, cartilage and menisci after a single administration of 200 mg were determined at different intervals in a group of patients with an average age of 80 years. Concentrations of 0.11 to 0.94 mg/kg bone tissue were measured after 0.5 to 5 hours. In the cartilage a conc...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01642108

    authors: Wacha H,Wagner D,Schäfer V,Knothe H

    更新日期:1990-05-01 00:00:00

  • [A microbiological method for the rapid determination of antibiotic concentrations during therapy].

    abstract::The assay described is an agar diffusion test using Bacillus stearothermophilus as test organism. Incubation is at 62° C; results can be obtained rapidly within 2 to 3 hours. The test was developed for the determination of gentamicin concentrations in serum and other body fluids. Because of its high sensitivity the te...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01642093

    authors: Wahlig H

    更新日期:1977-06-01 00:00:00

  • Thrombotic microangiopathies and HIV infection: report of two typical cases, features of HUS and TTP, and review of the literature.

    abstract::Haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are thrombotic microangiopathies increasingly reported in patients with HIV infection. However, characteristic features of thrombotic microangiopathies associated with HIV disease have not been defined yet. The typical courses of HUS and T...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF02565164

    authors: Sutor GC,Schmidt RE,Albrecht H

    更新日期:1999-01-01 00:00:00

  • A review on anti-adhesion therapies of bacterial diseases.

    abstract:BACKGROUND:Infections caused by bacteria are a foremost cause of morbidity and mortality in the world. The common strategy of treating bacterial infections is by local or systemic administration of antimicrobial agents. Currently, the increasing antibiotic resistance is a serious and global problem. Since the most impo...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-018-1222-5

    authors: Asadi A,Razavi S,Talebi M,Gholami M

    更新日期:2019-02-01 00:00:00

  • Susceptibility of frequent urinary pathogens to fosfomycin trometamol and eight other antibiotics: results of an Italian multicenter survey.

    abstract::In order to assess the resistance profile for fosfomycin trometamol after several years of clinical use in Italy, this study has explored the susceptibility to fosfomycin and eight other antibacterial drugs of 6,021 strains isolated from 23,816 urines during 1990 in three teaching hospitals located in Genoa, Parma and...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1007/BF01710017

    authors: Schito GC,Chezzi C,Nicoletti G,Moreddu M,Arcangeletti MC,Stefani S,Albini E,Del Bono GP

    更新日期:1992-01-01 00:00:00

  • Pharmacokinetics of imipenem in patients undergoing major colon surgery.

    abstract::Ten patients about to undergo a colorectal operation lasting an average of three hours received 500 mg each of imipenem and cilastatin i.v. preoperatively. During the operation blood and tissue samples were taken in order to determine the serum kinetics of the substances as well as the levels of imipenem in the cutis,...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01646409

    authors: Erttmann M,Krausse R,Ullmann U

    更新日期:1990-11-01 00:00:00

  • Oxacillin-susceptible methicillin-resistant Staphylococcus aureus (OS-MRSA), a hidden resistant mechanism among clinically significant isolates in the Wessex region/UK.

    abstract:PURPOSE:Methicillin-resistant Staphylococcus aureus (MRSA) is defined as S. aureus genetically having the mecA or mecC genes or phenotypically showing minimum inhibitory concentration (MIC) of oxacillin higher than 2 mg/L. However, recently, cefoxitin/oxacillin-susceptible mecA-positive S. aureus (OS-MRSA) has been rep...

    journal_title:Infection

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s15010-014-0641-1

    authors: Saeed K,Ahmad N,Dryden M,Cortes N,Marsh P,Sitjar A,Wyllie S,Bourne S,Hemming J,Jeppesen C,Green S

    更新日期:2014-10-01 00:00:00

  • The optimal management of lower urinary tract infections.

    abstract::Lower urinary tract infection is a common problem for women, and tends to be recurrent. It is not associated with significant long term morbidity. Optimal management for symptomatic infection is short course antimicrobial therapy. For women with frequent, symptomatic, recurrent infection a number of therapeutic option...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01643426

    authors: Nicolle LE

    更新日期:1990-01-01 00:00:00

  • Findings from an outbreak of carbapenem-resistant Klebsiella pneumoniae emphasize the role of antibiotic treatment for cross transmission.

    abstract:PURPOSE:In January 2015, we noticed by rectal swab analyses that seven of 23 patients at an early rehabilitation ward had been colonized with carbapenem-resistant Klebsiella pneumoniae (CKP). Here, we describe risk factors for CKP acquisition. METHODS:In the present study, the outbreak is described and risk factors fo...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-017-1103-3

    authors: Borgmann S,Pfeifer Y,Becker L,Rieß B,Siegmund R,Sagel U

    更新日期:2018-02-01 00:00:00

  • Effective treatment of urinary tract infections.

    abstract::In prescribing any particular antimicrobial agent for the treatment of urinary tract infection decisions have to be made on the choice of drug, on the basis of bacteriological findings, the dosage and the duration of administration. These problems are reviewed below in conjunction with the criteria of successful thera...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644939

    authors: Acar JF

    更新日期:1980-01-01 00:00:00

  • The "Choosing Wisely" initiative in infectious diseases.

    abstract:OBJECTIVE:"Choosing Wisely" is a growing international campaign aiming at practice changes to improve patient health and safety by both, conduct of essential and avoidance of unnecessary diagnostic, preventive and therapeutic procedures. The goal is to create an easily recognizable and distributable list ("Choosing Wis...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-017-0997-0

    authors: Lehmann C,Berner R,Bogner JR,Cornely OA,de With K,Herold S,Kern WV,Lemmen S,Pletz MW,Ruf B,Salzberger B,Stellbrink HJ,Suttorp N,Ullmann AJ,Fätkenheuer G,Jung N

    更新日期:2017-06-01 00:00:00

  • Staphylococcus aureus meningitis in adults: a clinical comparison of infections caused by methicillin-resistant and methicillin-sensitive strains.

    abstract:BACKGROUND:This study was undertaken to compare the clinical characteristics of adult methicillin-sensitive Staphylococcus aureus (MSSA) meningitis and adult methicillin-resistant S. aureus (MRSA) meningitis. PATIENTS AND METHODS:The clinical characteristics and therapeutic outcomes of 19 adult patients with S. aureus...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-001-1092-z

    authors: Chang WN,Lu CH,Wu JJ,Chang HW,Tsai YC,Chen FT,Chien CC

    更新日期:2001-10-01 00:00:00

  • [Erythromycin determination in organ tissues (author's transl)].

    abstract::The recovery rates of erythromycin after in vitro and in vivo administration were studied comparatively in liver, lung, and kidney. Using buffer standards the recovery rate in homogenates of in vitro administered erythromycin decreased with increasing protein concentration. At constant protein concentration the erythr...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641124

    authors: Dette GA,Finke U

    更新日期:1979-01-01 00:00:00

  • Group B streptococcal disease in infants in the first year of life: a nationwide surveillance study in Japan, 2011-2015.

    abstract:PURPOSE:This study aimed to describe the epidemiology of childhood group B streptococcus (GBS) disease including late late-onset disease (LLOD) and to clinically characterize recurrent cases and twin-sibling cases in Japan. METHODS:We collected information on infants (<1 year of age) with invasive GBS disease and inst...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-017-0995-2

    authors: Matsubara K,Hoshina K,Kondo M,Miyairi I,Yukitake Y,Ito Y,Minami K,Genkawa R

    更新日期:2017-08-01 00:00:00

  • Lymphocyte apoptosis, caspase activation and inflammatory response in septic shock.

    abstract:BACKGROUND:We examined lymphocyte apoptosis, activity of caspases-1, -3, -8 and -9 and the relationship between those two events and inflammation response in septic shock. MATERIALS AND METHODS:Blood samples were obtained within 24 h after diagnosis of septic shock from 16 patients to measure apoptosis, caspases-3, -8...

    journal_title:Infection

    pub_type: 信件

    doi:10.1007/s15010-008-7070-y

    authors: Delogu G,Famularo G,Tellan G,Marandola M,Antonucci A,Signore M,Marcellini S,Moretti S

    更新日期:2008-10-01 00:00:00

  • Association in the seroprevalence of hepatitis A and herpes simplex-1 viruses in young adults in Israel.

    abstract:BACKGROUND:The rise in the standard of living of the Israeli population during recent decades has been accompanied by a significant decline in the prevalence of various viral diseases including hepatitis A (HAV). This trend is not reflected in the seroprevalence of herpes simplex (HSV) infection, which has remained sta...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s150100070042

    authors: Katz J,Gdalevich M,Ashkenazi I,Chaushu G,Shemer J

    更新日期:2000-07-01 00:00:00

  • Duration of posaconazole therapy for Aspergillus fumigatus osteomyelitis dictated by serial monitoring of 1,3-beta-D glucan.

    abstract::Here, we present a case of an immunocompetent 37-year old male who developed Aspergillus fumigatus osteomyelitis 16 years after extensive chest wall reconstructive surgery for Ewing sarcoma. His treatment course was complicated by a severe adverse drug reaction to voriconazole, requiring the use of oral posaconazole t...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-020-01489-2

    authors: Doub JB,Mathur P

    更新日期:2020-12-01 00:00:00

  • Success of MRSA eradication in hospital routine: depends on compliance.

    abstract:BACKGROUND:To prevent transmission of MRSA, eradication by antiseptic washings and nasal ointment is recommended. There are few studies, which investigated the success of eradication of MRSA carriage during everyday clinical working conditions and results are controversial. We wanted to assess the effectiveness of MRSA...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-007-6273-y

    authors: Hansen D,Patzke PI,Werfel U,Benner D,Brauksiepe A,Popp W

    更新日期:2007-06-01 00:00:00

  • A before-after study of multi-resistance and cost of selective decontamination of the digestive tract.

    abstract:BACKGROUND:We compared standard antibiotic use with an antibiotic policy based on selective decontamination of the digestive tract (SDD) for cost and microbiology. PATIENTS AND METHODS:A 2-year before-after observational study was performed in an 11-bed, mixed medical and surgical intensive care unit (ICU). We include...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-004-3170-5

    authors: van der Voort PH,van Roon EN,Kampinga GA,Boerma EC,Gerritsen RT,Egbers PH,Kuiper MA

    更新日期:2004-10-01 00:00:00