Ciprofloxacin concentrations in tonsils following a single intravenous infusion.

Abstract:

:Penetration of ciprofloxacin into human tonsils was studied following an intravenous infusion of 200 mg over 15 minutes to adult humans undergoing tonsillectomy. Samples were taken one-and-a-half to four hours after dosing. Generally, tissue levels exceeded corresponding serum concentrations by 50% (range of intraindividual ratios between tonsil and serum concentrations 100% to 288%). Ciprofloxacin distribution was homogeneous and independent of sampling time.

journal_name

Infection

journal_title

Infection

authors

Falser N,Dalhoff A,Weuta H

doi

10.1007/BF01651152

subject

Has Abstract

pub_date

1984-09-01 00:00:00

pages

355-7

issue

5

eissn

0300-8126

issn

1439-0973

journal_volume

12

pub_type

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