Femoral osteomyelitis due to Cladophialophora arxii in a patient with chronic granulomatous disease.

Abstract:

:Fungal infections in patients with chronic granulomatous disease (CGD) are a poor prognostic factor. We describe the first case of CGD with femoral osteomyelitis due to Cladophialophora arxii, which is a member of the dematiaceous group. The causative fungus was identified on the basis of its morphological characteristics, growth temperature profile, and nucleotide sequence on the internal transcribed space region of the ribosomal gene. The patient was successfully treated with surgical debridement, subsequent administration of itraconazolem and interferon-gamma.

journal_name

Infection

journal_title

Infection

authors

Shigemura T,Agematsu K,Yamazaki T,Eriko K,Yasuda G,Nishimura K,Koike K

doi

10.1007/s15010-009-8238-9

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

469-73

issue

5

eissn

0300-8126

issn

1439-0973

journal_volume

37

pub_type

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