Abstract:
:Fungal infections in patients with chronic granulomatous disease (CGD) are a poor prognostic factor. We describe the first case of CGD with femoral osteomyelitis due to Cladophialophora arxii, which is a member of the dematiaceous group. The causative fungus was identified on the basis of its morphological characteristics, growth temperature profile, and nucleotide sequence on the internal transcribed space region of the ribosomal gene. The patient was successfully treated with surgical debridement, subsequent administration of itraconazolem and interferon-gamma.
journal_name
Infectionjournal_title
Infectionauthors
Shigemura T,Agematsu K,Yamazaki T,Eriko K,Yasuda G,Nishimura K,Koike Kdoi
10.1007/s15010-009-8238-9subject
Has Abstractpub_date
2009-10-01 00:00:00pages
469-73issue
5eissn
0300-8126issn
1439-0973journal_volume
37pub_type
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