Abstract:
:ATRIPLA is licensed for use only in HIV-positive persons whose viral loads <50 for ≥ 3 months. We investigated the use of ATRIPLA as first-line antiretroviral therapy (ART) in EuroSIDA using a web-based survey performed in Autumn 2012. 96/112 clinics (85.7 %) completed the survey. Recommendations when initiating first-line ART was TRUVADA plus efavirenz in 36 (37.5 %), ATRIPLA in 35 (36.5 %), a different first-line regimen in 12 clinics (12.5 %), and no recommendation in 7 clinics (7.3 %). ATRIPLA was commonest in Northern (15/21 clinics; 71.4 %), and least common in Eastern Europe (2/31 clinics; 6.5 %; p < 0.0001). Over one-third of the participating clinics in this survey were using ATRIPLA as first-line antiretroviral therapy, despite EMA recommendations.
journal_name
Infectionjournal_title
Infectionauthors
Mocroft A,Reiss P,Rakhmanova A,Banhegyi D,Phillips AN,De Wit S,Ristola M,Lundgren JD,Grarup J,Kirk O,EuroSIDA in EuroCOORD.doi
10.1007/s15010-014-0630-4subject
Has Abstractpub_date
2014-08-01 00:00:00pages
757-62issue
4eissn
0300-8126issn
1439-0973journal_volume
42pub_type
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